disopyramide and theophylline

disopyramide has been researched along with theophylline in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's3 (14.29)18.2507
2000's9 (42.86)29.6817
2010's7 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Draper, P; Lemieux, B; Shapcott, D1
Bryson, SM; Kelman, AW; Whiting, B1
Akhtar, M; Blanck, Z; Deshpande, S; Dhala, A; Jazayeri, M; Natale, A; Sra, J; Wase, A1
Akhtar, M; Avitall, B; Blanck, Z; Deshpande, S; Dhala, A; Jazayeri, MR; Sra, JS1
Grubb, BP; Kosinski, D; Mouhaffel, A; Pothoulakis, A1
Cadman, CS1
Freeman, R; Kaufmann, H1
Brignole, M; Deharo, JC; Franceschi, F; Guieu, R; Hourdain, J; Koutbi, L; Perrin, T1

Reviews

3 review(s) available for disopyramide and theophylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Medical therapy of neurocardiogenic syncope.
    Cardiology clinics, 2001, Volume: 19, Issue:2

    Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Child; Cholinergic Antagonists; Disopyramide; Fluid Therapy; Humans; Mineralocorticoids; Parasympathetic Nervous System; Selective Serotonin Reuptake Inhibitors; Sodium Chloride, Dietary; Sympathetic Nervous System; Syncope, Vasovagal; Theophylline; Tilt-Table Test

2001
Pharmacological treatment of reflex syncope.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2004, Volume: 14 Suppl 1

    Topics: Adrenergic Agents; Anti-Arrhythmia Agents; Cholinergic Antagonists; Disopyramide; Humans; Selective Estrogen Receptor Modulators; Syncope, Vasovagal; Theophylline

2004

Trials

1 trial(s) available for disopyramide and theophylline

ArticleYear
Efficacy of different treatment strategies for neurocardiogenic syncope.
    Pacing and clinical electrophysiology : PACE, 1995, Volume: 18, Issue:4 Pt 1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Disopyramide; Ephedrine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Syncope; Theophylline

1995

Other Studies

17 other study(ies) available for disopyramide and theophylline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Single column high pressure liquid chromatographic determination of drugs in blood.
    Clinical biochemistry, 1979, Volume: 12, Issue:2

    Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Disopyramide; Humans; Pyridines; Theophylline

1979
OPT: a package of computer programs for parameter optimisation in clinical pharmacokinetics.
    British journal of clinical pharmacology, 1982, Volume: 14, Issue:2

    Topics: Administration, Oral; Biological Availability; Computers; Disopyramide; Gentamicins; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Models, Biological; Pharmaceutical Preparations; Theophylline

1982
Comparison of cardiac pacing with drug therapy in the treatment of neurocardiogenic (vasovagal) syncope with bradycardia or asystole.
    The New England journal of medicine, 1993, Apr-15, Volume: 328, Issue:15

    Topics: Adolescent; Adult; Aged; Bradycardia; Cardiac Pacing, Artificial; Disopyramide; Female; Follow-Up Studies; Heart Arrest; Humans; Hypotension; Male; Metoprolol; Middle Aged; Posture; Recurrence; Syncope; Theophylline

1993
The use of methylphenidate in the treatment of refractory neurocardiogenic syncope.
    Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:5

    Topics: Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Adult; Bradycardia; Central Nervous System Stimulants; Disopyramide; Female; Fludrocortisone; Follow-Up Studies; Humans; Hypotension; Methylphenidate; Middle Aged; Posture; Recurrence; Selective Serotonin Reuptake Inhibitors; Syncope; Theophylline; Tilt-Table Test; Vasoconstrictor Agents

1996
Theophylline as an adjunct to control malignant ventricular arrhythmia associated with early repolarization.
    Pacing and clinical electrophysiology : PACE, 2018, Volume: 41, Issue:5

    Topics: Anti-Arrhythmia Agents; Child; Defibrillators, Implantable; Disopyramide; Humans; Male; Quinidine; Recurrence; Tachycardia, Ventricular; Theophylline; Vasodilator Agents

2018