disopyramide has been researched along with quinidine in 244 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 182 (74.59) | 18.7374 |
| 1990's | 28 (11.48) | 18.2507 |
| 2000's | 18 (7.38) | 29.6817 |
| 2010's | 14 (5.74) | 24.3611 |
| 2020's | 2 (0.82) | 2.80 |
| Authors | Studies |
|---|---|
| Barcelon-Yang, C; Brown, BS; Matier, WL; Reynolds, RD; Stout, DM | 2 |
| Haruna, M; Kida, S; Kimoto, S; Matsumoto, H; Ogata, M; Shimizu, S; Takahashi, K; Ueda, M | 1 |
| Bernhart, CA; Condamine, C; Demarne, H; Gagnol, JP; Gautier, PJ; Roncucci, R; Serre, MA | 1 |
| Bourgery, G; Dostert, P; Lacour, A; Langlois, M; Pourrias, B; Tisne-Versailles, J | 1 |
| Hershenson, FM; Novotney, RL; Prodan, KA; Woo, CM; Yonan, PK | 1 |
| Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE | 1 |
| Giacomini, KM; Schaner, ME; Zhang, L | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R | 1 |
| Theisen, K | 2 |
| Donaldson, RM | 1 |
| Nisbet, T | 1 |
| Grewe, N; Nissen, H; Stauch, M | 1 |
| Smith, WS | 1 |
| Ruffy, R; Zipes, DP | 1 |
| Oshrain, C | 1 |
| Romankiewicz, JA | 1 |
| Singh, BN | 1 |
| Shand, DG; Woosley, RL | 1 |
| Koch-Weser, J | 1 |
| Breithardt, G; Jochum, E; Kuhn, H; Seipel, L | 1 |
| Forester, D | 1 |
| Federman, J; Vlietstra, RE | 1 |
| Tri, TB | 1 |
| Horwitz, LD; Walsh, RA | 1 |
| Kus, T; Sasyniuk, BI | 1 |
| Pennock, RS | 1 |
| Anderson, JL; Harrison, DC; Meffin, PJ; Winkle, RA | 1 |
| Lagerström, PO; Persson, BA | 1 |
| Bellows, JG | 1 |
| Ankier, SI; Grant, AM; Marshall, RJ | 1 |
| Castellanos, A; Myerburg, RJ; Rozanski, JJ; Sung, RJ | 1 |
| Mason, JW; Winkle, RA | 1 |
| Farshidi, A; Greenspan, AM; Horowitz, LN; Josephson, ME; Michelson, EL; Spielman, SR | 1 |
| Martin, RP; McMorrow, M; Meltzer, RS; Robert, EW | 1 |
| Danilo, P; Rosen, MR | 1 |
| Barrillon, A; Grand, A | 1 |
| Boyd, RB; Harner, RH | 1 |
| Loogen, F | 1 |
| Kidner, PH | 1 |
| Scholz, H | 1 |
| Cusic, JW; Ellefson, CR | 1 |
| Hohansson, BW; Persson, S | 1 |
| Fowler, NO | 1 |
| Dreifus, LS | 1 |
| Befeler, B | 1 |
| Dean, RR | 1 |
| Araú, A; Bonhorst, D; Bordalo, A; De Azevedo, JG; Ferreira, M; Ferreira, R; Inês, L; Lacximy, I; Longo, A; Luis Martins, J; Melo, M; Nunes Diogo, A; Ribeiro, C; Sanches, C; Teixeira, J | 1 |
| Aliot, E; Gilgenkrantz, JM; Maureira, JJ | 1 |
| Honda, Y; Kawai, H; Kawashima, T; Nakatani, M; Shite, J; Takeuchi, Y; Tsumura, Y; Ueno, H; Yokota, Y | 1 |
| Furukawa, T; Hiraoka, M; Marumo, F; Nitta, J; Sawanobori, T; Sunami, A | 1 |
| Hayakawa, H; Hisatome, I; Katori, R; Koumi, S; Nagasawa, K; Sato, R | 1 |
| Kanno, M; Nakaya, H; Oyama, Y; Shishido, Y | 1 |
| Hanano, M; Iga, T; Okudaira, K; Sawada, Y; Sugiyama, Y; Yamazaki, M | 1 |
| Fomina, IG; Iankin, VV | 1 |
| Abdalla, A; Mazur, NA; Nazarenko, VA | 1 |
| Akaike, N; Inomata, N; Ishihara, T | 1 |
| Boudoulas, H; Coyle, JD; Lewis, RP; Lima, JL; Mackichan, JJ | 1 |
| Anderson, JL | 1 |
| Fisher, JD; Kim, SG; Matos, JA; Seiden, SW; Waspe, LE | 1 |
| Podrid, PJ | 3 |
| Honerjäger, P; Loibl, E; Schönsteiner, G; Steidl, I; Ulm, K | 1 |
| Keefe, DL; Miura, D; Somberg, JC | 1 |
| Greenspan, AM; Horowitz, LN; Spielman, SR | 1 |
| Au, PK; Bhandari, AK; Bream, R; Rahimtoola, SH; Schreck, D; Siddiqi, R | 1 |
| Abdalla, A; Iavorskaia, NV; Mazur, NA; Sumarokov, AB | 1 |
| Hasegawa, J; Hirokane, Y; Kotake, H; Mashiba, H; Nawada, T; Noguchi, N | 1 |
| Hoffmeister, HM; Krämer, B; Pflug, A; Seipel, L | 1 |
| Manito, N; Oriol, A; Roca, J | 1 |
| Somberg, J | 1 |
| Roden, DM; Siddoway, LA; Woosley, RL | 1 |
| Roy, D | 1 |
| Ito, H; Kurachi, Y; Nakajima, T; Sugimoto, T; Takikawa, R | 1 |
| Belhassen, B; Laniado, S; Pines, A | 1 |
| Amiel, A; Boutaud, P; Ciber, M; Demange, J; Guillem, JP; Herpin, D; Maarek-Charbit, M | 1 |
| Brachmann, J; Gao, TL; Senges, J | 1 |
| Echt, DS; Roden, DM; Woosley, RL | 1 |
| Morganroth, J; Nestico, PF | 3 |
| Huang, SK; Marcus, FI | 1 |
| Wood, M | 1 |
| Proelss, HF; Townsend, TB | 1 |
| Light, RT; Onrot, J; Robertson, D; Robertson, RM; Tantengco, MV | 1 |
| Kates, RE | 2 |
| Hepp, A; Hoffmeister, HM; Seipel, L | 2 |
| Cody, DV; Denniss, AR; Richards, DA; Ross, DL; Russell, PA; Uther, JB; Young, AA | 1 |
| Hashimoto, S; Horie, M; Ikeguchi, S; Kadoya, M; Kawai, C; Konishi, T | 1 |
| Garan, H; McElroy, M; McGovern, B; Newell, JB; Ruskin, JN; Schoenfeld, MH; Whitford, EG | 1 |
| Lundström, T; Rydén, L | 1 |
| Bauma, W; Bauman, JL; Beckman, KJ; Berry, NS; Gallastegui, JL; Hariman, RJ | 1 |
| Heger, JJ; Miles, WM; Minardo, JD; Prystowsky, EN; Zipes, DP | 1 |
| Duff, HJ; Mitchell, LB; Wyse, DG | 1 |
| Brachmann, J; Kübler, W; Lengfelder, W; Rizos, I; Schmitt, C; Senges, J; von Olshausen, K | 1 |
| Bardy, GH; Fahrenbruch, CE; Graham, EL; Greene, HL; Poole, JE; Pulaski, WP; Werner, JA | 1 |
| Akioka, K; Horiguchi, T; Ikuno, Y; Inoue, E; Oku, H; Takeda, T; Takeuchi, K; Teragaki, M; Toda, I; Yasuda, M | 1 |
| Belhassen, B; Laniado, S; Miller, H; Paredes, A; Shapira, I; Shoshani, D | 1 |
| Gardner, MJ; Josephson, ME; McCarthy, DM | 1 |
| Fossati, C | 1 |
| Hirosawa, K; Kasanuki, H; Onishi, S | 1 |
| Collignon, P; Legrand, V | 1 |
| Atarashi, H; Hayakawa, H | 1 |
| Hashimoto, S; Kanazawa, T; Miura, M; Ono, Y | 1 |
| Hauswirth, O; Singh, BN | 1 |
| Mathur, PP | 1 |
| Carlier, J; Lisin, N | 2 |
| Casagrande, C; Ferrari, G; Ferrini, R; Galli, A; Miragoli, G | 1 |
| Chien, YW; Karim, A; Lambert, HJ | 1 |
| Lomanto, B; Rossi, A; Sanna, GP | 1 |
| Combre, A; Duchêne-Marullaz, P; Lapalus, P; Lavarenne, J | 1 |
| Scherlag, BJ; Sung, PK; Yeh, BK | 1 |
| Aquaro, G; D'Arrigo, A; Pavia, M; Poletti, T | 1 |
| Opie, LH | 1 |
| Schmitz, W | 1 |
| DiBianco, R; Fletcher, RD; Gottdiener, JS | 1 |
| Attuel, P; Coumel, P; Georgiopoulos, G; Halkidis, H; Leclercq, JF; Maisonblanche, P | 1 |
| Elkayam, U; Frishman, W; Rotmensch, HH | 1 |
| Hillis, WS; Whiting, B | 1 |
| Kuch, J | 1 |
| Prystowsky, EN | 1 |
| Somberg, JC | 1 |
| Doherty, JU; Josephson, ME; Kienzle, MG; Williams, PD; Zygmont, D | 1 |
| Jahrmärker, H; Theisen, K | 1 |
| Lalka, D; McNamara, PJ; Pieper, JA; Slaughter, RL; Wyman, MG | 1 |
| Halawa, B; Mazurek, W | 1 |
| Lasky, FD; Wesley, JF | 2 |
| Garson, A; Gillette, PC | 1 |
| Howanitz, JH; Howanitz, PJ | 1 |
| Barnay, C; Bricaud, H; Clémenty, J; Denis, B; Dimitrio, R; Egre, A; Machecourt, J; Medvedowsky, JL; Pellet, J; Wolf, JE | 1 |
| Roden, DM; Woosley, RL | 1 |
| Mirro, MJ | 1 |
| Bexton, RS; Camm, AJ | 1 |
| Forman, R; Gersh, BJ; Lloyd, EA | 1 |
| Bobba, P; Chimienti, M; Cristiani, D; Panciroli, C; Previtali, M; Regazzi-Bonora, M; Rondanelli, R; Salerno, JA | 1 |
| Arif, M; Karim, A; Laidlaw, JC; McDermott, DJ; Nissen, CH; Oshrain, C; Smith, WS; Willis, PW; Wilson, RR | 1 |
| Rosen, MR; Wit, AL | 1 |
| Block, PJ; Winkle, RA | 1 |
| DePace, NL; Morganroth, J; Nestico, PF | 1 |
| Fuster, V; Goldman, ME; Kupersmith, J; Schweitzer, P; Squire, A; Stern, EH | 1 |
| Cerskus, I; Roden, DM; Siddoway, LA; Thompson, K; Woosley, RL | 1 |
| Gebhardt, VA; Goddard, MD; Gryfe-Becker, B; Nichol, PM; Prato, FS; Rechnitzer, PA; Wisenberg, G; Zawadowski, AG | 1 |
| Chiba, S; Kobayashi, M; Shimotori, M | 1 |
| Bricaud, H; Lévy, RH; Lévy, S | 1 |
| Flouvat, B | 1 |
| Bailey, JC; Nattel, S | 1 |
| Buxton, AE; Josephson, ME; Sadowski, LM; Waxman, HL | 1 |
| Baker, BJ; Doherty, JE; Gammill, J; Karin, A; Massengill, J; Schubert, E | 1 |
| Bauernfeind, RA; Coelho, A; Gallastegui, J; Petropoulos, AT; Rosen, KM; Swiryn, S | 1 |
| Bauernfeind, RA; Duffy, CE; Palileo, E; Rosen, KM; Strasberg, B; Swiryn, S | 1 |
| Arensberg, D; Felner, JM; Stanford, JL | 1 |
| Hunt, D; Manolas, EG; Sloman, G | 1 |
| Bowers, GN; Flood, JG; McComb, RB | 1 |
| Dreifus, LS; Morganroth, J | 1 |
| Moses, HW; Yu, PN | 1 |
| Witkowska, M | 1 |
| McAnulty, JH; Metcalfe, J; Ueland, FR; Ueland, K | 1 |
| Garfein, OB | 1 |
| Drake, CE | 1 |
| Benhorin, J; Gottlieb, S; Keren, A; Stern, S; Tzivoni, D | 1 |
| Basseches, PJ; DiGregorio, GJ; Piraino, AJ; Ruch, EK | 1 |
| Bauernfeind, RA; Palileo, E; Rosen, KM; Scagliotti, D; Strasberg, B; Swiryn, SP | 1 |
| Coelho, A; Rosen, KM; Strasberg, B; Welch, WJ | 1 |
| Bauernfeind, RA; Iverson, N; Levy, PS; Palileo, E; Rosen, KM; Strasberg, B; Swiryn, S | 1 |
| Gulamhusein, S; Klein, GJ; Ko, PT; Kostuk, WJ | 1 |
| Ahokas, JT; Norris, RL; Ravenscroft, PJ | 1 |
| Beck, OA; Günther, R; Hochrein, H | 1 |
| Ashkenazi, J; Feigl, D; Schwarzmann, H | 1 |
| Bailey, JC; Manalan, AS; Mirro, MJ; Watanabe, AM | 1 |
| Bailey, JC; Mirro, MJ; Watanabe, AM | 2 |
| Chen, SH; Kabra, PM; Marton, LJ | 1 |
| Affrime, MB; Lowenthal, DT | 1 |
| Benfey, BG | 1 |
| McEniry, DW; Skorton, DJ | 1 |
| Hasin, Y; Rogel, S; Sarel, O | 1 |
| Colman, JM; Wald, RW; Waxman, MB | 1 |
| Benhorin, J; Corcos, P; Golhman, JM; Keren, A; Stern, S; Tzivoni, D | 1 |
| Benhorin, J; Gavish, D; Gottlieb, S; Keren, A; Levi, J; Stern, S; Tzivoni, D | 1 |
| Chiavarelli, V; Milazzotto, F; Vajola, SF | 1 |
| Engler, RL | 1 |
| Abbott, JA; Cheitlin, MD; Desai, J; Holford, N; Peters, RW; Remedios, P; Scheinman, MM | 1 |
| Bigger, JT; Giardina, EG; Leahey, EB; Reiffel, JA | 1 |
| Ahokas, JT; Davies, C; Ravenscroft, PJ | 1 |
| Breithardt, G; Haerten, K; Seipel, L | 1 |
| Grey, E; Silverman, DI | 1 |
| Bursill, JA; Campbell, TJ; Wyse, KR | 2 |
| Ishii, K; Taira, N; Yamagishi, T | 1 |
| Campbell, TJ; Wyse, KR; Ye, V | 2 |
| Bridal, TR; de Lorenzi, FG; Spinelli, W | 1 |
| Grant, AO; Starmer, CF; Zilberter, YI | 1 |
| Lüderitz, B; Manz, M | 1 |
| Fromm, BS; Lehmann, MH; Makkar, RR; Meissner, MD; Steinman, RT | 1 |
| Brechenmacher, C; Chauvin, M; Koenig, A; Theolade, R | 1 |
| Chemtob, S; Deng, XF; Mulay, S; Varma, DR | 1 |
| Matsumori, A; Nishio, R; Nose, Y; Ono, K; Sasayama, S | 1 |
| Beurrier, D; Brembilla-Perrot, B; Danchin, N; Houplon, P; Jacquemin, L; Louis, P; Terrier de la Chaise, A | 1 |
| Fernández del Pozo, B; Fernández, C; Pérez-Vizcaíno, F; Tamargo, J; Zaragozá, F | 1 |
| Ruskin, JN | 1 |
| Iost, N; Papp, JG; Varró, A; Virág, L | 1 |
| Benest, AV; Hancox, JC; Masters, JD; Milnes, JT; Ridley, JM; Witchel, HJ | 1 |
| Buszman, E; Rózańska, R | 1 |
| SEKIYA, A; VAUGHANWILLIAMS, EM | 1 |
| Endou, H; Enomoto, A; Hasannejad, H; Huang, XL; Jung, SH; Narikawa, S; Niwa, T; Onozato, ML; Takeda, M; Taki, K; Tojo, A | 1 |
| Scharf, C | 1 |
| Borggrefe, M; Gaita, F; Giustetto, C; Schimpf, R; Veltmann, C; Wolpert, C | 1 |
| Kodama, S; Maruyama, S; Miyoshi, K; Shiga, Y; Sumi, S; Tojou, H; Urata, H; Yamanouchi, Y | 1 |
| Ghias, M; Jackman, WM; Lazzara, R; Lu, Z; Moers, AM; Niu, G; Po, SS; Scherlag, BJ | 1 |
| Luo, C; Wang, K; Zhang, H | 2 |
| Brignole, M; Deharo, JC; Franceschi, F; Guieu, R; Hourdain, J; Koutbi, L; Perrin, T | 1 |
| Bai, J; Gao, M; Lo, A; Lu, Y; Zhang, H; Zhao, J; Zhu, Y | 1 |
45 review(s) available for disopyramide and quinidine
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Rational basis of antiarrhythmic therapy: clinical pharmacology of commonly used antiarrhythmic drugs.
Topics: Action Potentials; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Disopyramide; Heart; Humans; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine; Sympatholytics; Time Factors | 1978 |
Pharmacokinetics of antiarrhythmic drugs.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Glycine; Half-Life; Injections, Intravenous; Kinetics; Lidocaine; Procainamide; Quinidine | 1978 |
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Disopyramide; Drug Evaluation; Humans; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Time Factors; Ventricular Fibrillation | 1978 |
Cardiac effects of disopyramide.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Atrioventricular Node; Clinical Trials as Topic; Disopyramide; Dogs; Heart; Heart Block; Heart Conduction System; Hemodynamics; Humans; Myocardial Contraction; Pyridines; Quinidine; Rabbits | 1976 |
[Incompatibility and interference of the major cardiologic drugs. Their undesirable effects].
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antihypertensive Agents; Bradycardia; Cardiac Glycosides; Digitalis Glycosides; Disopyramide; Drug Interactions; Drug Synergism; Humans; Hypertension; Hypokalemia; Isoproterenol; Lidocaine; Monoamine Oxidase Inhibitors; Ouabain; Phenytoin; Prenylamine; Procainamide; Quinidine | 1976 |
Comparisons of efficacy and tolerance of moricizine with other antiarrhythmic agents in the treatment of chronic ventricular arrhythmias.
Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Double-Blind Method; Encainide; Female; Flecainide; Humans; Male; Moricizine; Phenothiazines; Propranolol; Quinidine; Randomized Controlled Trials as Topic | 1990 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Death, Sudden; Disopyramide; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Random Allocation; Tocainide | 1985 |
The treatment of ventricular rhythm disturbances.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Electric Countershock; Electric Stimulation; Electrocardiography; Exercise Test; Flecainide; Heart Ventricles; Humans; Lidocaine; Phenytoin; Piperidines; Procainamide; Quinidine; Risk; Tachycardia; Tocainide; United States; Ventricular Fibrillation; Verapamil | 1986 |
Combination antiarrhythmic drug therapy for ventricular tachyarrhythmias.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Heart Conduction System; Heart Ventricles; Humans; Monitoring, Physiologic; Procainamide; Quinidine; Tachycardia | 1986 |
[Physiopathology of the transplanted heart. Review and clinical implications].
Topics: Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Catecholamines; Coronary Circulation; Digoxin; Disopyramide; Dogs; Electrocardiography; Exercise Test; Follow-Up Studies; Heart; Heart Transplantation; Hemodynamics; Humans; Quinidine; Time Factors | 1989 |
Antiarrhythmic drug therapy. Recent advances and current status.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil | 1985 |
Clinical pharmacology of old and new antiarrhythmic drugs.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide | 1985 |
Antiarrhythmic drugs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium Channel Blockers; Cell Membrane; Disopyramide; Electrophysiology; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide | 1986 |
Effects of congestive heart failure on the pharmacokinetics and pharmacodynamics of antiarrhythmic agents.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Digitalis; Disopyramide; Drug Interactions; Encainide; Flecainide; Half-Life; Heart Failure; Hemodynamics; Humans; Kidney; Kinetics; Lidocaine; Liver; Piperidines; Plants, Medicinal; Plants, Toxic; Potassium; Procainamide; Quinidine; Regional Blood Flow; Tocainide | 1986 |
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment.
Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil | 1986 |
Antiarrhythmic drug therapy of ventricular arrhythmias.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil | 1986 |
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Cardiac Surgical Procedures; Chlorpromazine; Dipyridamole; Disopyramide; Etidocaine; Female; Fentanyl; Half-Life; Humans; Imipramine; Kidney Diseases; Lidocaine; Liver; Mathematics; Meperidine; Methadone; Myocardial Infarction; Orosomucoid; Prazosin; Pregnancy; Propranolol; Protein Binding; Quinidine; Serum Albumin; Sex Factors | 1986 |
Antiarrhythmic agents for chronic ventricular arrhythmias.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide | 1987 |
[Pharmacologic problems with teratogenic drugs].
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anesthetics; Anti-Arrhythmia Agents; Anticonvulsants; Disopyramide; Female; Humans; Phenytoin; Pregnancy; Propranolol; Quinidine; Solvents; Teratogens | 1985 |
[Treatment of extrasystole (ventricular and atrial extrasystoles)].
Topics: Adrenergic beta-Antagonists; Ajmaline; Aniline Compounds; Benzyl Compounds; Cardiac Complexes, Premature; Disopyramide; Hemodynamics; Humans; Imidazoles; Lidocaine; Phenytoin; Procainamide; Propanolamines; Propranolol; Quinidine | 1974 |
Comparative mechanisms of action of antiarrhythmic drugs.
Topics: Action Potentials; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Benzyl Compounds; Bretylium Compounds; Calcium; Carbamazepine; Chemical Phenomena; Chemistry; Diethylamines; Disopyramide; Heart; Humans; Imidazoles; Iodobenzoates; Lidocaine; Membrane Potentials; Phenyl Ethers; Phenytoin; Procainamide; Propylamines; Quinidine; Verapamil | 1974 |
[Electrophysiological classification of newer antiarrhythmic drugs (author's transl)].
Topics: Action Potentials; Adrenergic beta-Antagonists; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Quinidine; Sodium; Tocainide | 1980 |
Effects of antiarrhythmic agents on cardiac function.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Dogs; Encainide; Hemodynamics; Humans; Myocardial Contraction; Quinidine; Verapamil | 1982 |
Antiarrhythmic drug therapy during pregnancy.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Breast Feeding; Digitalis Glycosides; Disopyramide; Female; Fetus; Humans; Infant, Newborn; Lidocaine; Maternal-Fetal Exchange; Phenytoin; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Tachycardia; Verapamil | 1983 |
Pharmacologic therapy of tachyarrhythmias in patients with Wolff-Parkinson-White syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Ajmaline; Amiodarone; Anilides; Aprindine; Atrial Fibrillation; Benzofurans; Digitalis Glycosides; Disopyramide; Encainide; Female; Humans; Lidocaine; Male; Middle Aged; Procainamide; Quinidine; Tachycardia; Verapamil; Wolff-Parkinson-White Syndrome | 1983 |
Antiarrhythmic drug therapy for sustained ventricular tachycardia.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bethanidine; Calcium Channel Blockers; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Encainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Phenytoin; Piperidines; Procainamide; Quinidine; Tachycardia; Tocainide | 1984 |
[Medical treatment of extrasystole and tachycardia (author's transl)].
Topics: Action Potentials; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Digoxin; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1980 |
Antiarrhythmic drug monitoring.
Topics: Acecainide; Anti-Arrhythmia Agents; Disopyramide; Humans; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine | 1981 |
Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide.
Topics: Acecainide; Animals; Anti-Arrhythmia Agents; Disopyramide; Drug Interactions; Electrocardiography; Electrophysiology; Humans; Kinetics; Procainamide; Quinidine | 1983 |
Electropharmacology of antiarrhythmic drugs.
Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Electric Conductivity; Heart Atria; Heart Ventricles; Humans; Lidocaine; Membrane Potentials; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Procainamide; Propranolol; Purkinje Fibers; Quinidine; Tocainide; Verapamil | 1983 |
Hemodynamic effects of antiarrhythmic drugs.
Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Dose-Response Relationship, Drug; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Myocardial Contraction; Phenytoin; Piperidines; Procainamide; Quinidine; Tocainide | 1983 |
Therapy with conventional antiarrhythmic drugs for ventricular arrhythmias.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Heart Ventricles; Humans; Lidocaine; Procainamide; Propranolol; Quinidine; Tocainide | 1984 |
New insights into the drug treatment of ventricular arrhythmias.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Disopyramide; Humans; Kinetics; Lidocaine; Procainamide; Propranolol; Quinidine; Tocainide | 1984 |
Metabolites of cardiac antiarrhythmic drugs: their clinical role.
Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Disopyramide; Encainide; Humans; Lidocaine; Piperidines; Procainamide; Quinidine | 1984 |
Antiarrhythmic agents and their use in therapy.
Topics: Acebutolol; Animals; Anti-Arrhythmia Agents; Digitalis Glycosides; Disopyramide; Humans; Lidocaine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1980 |
Antiarrhythmic drugs.
Topics: Anti-Arrhythmia Agents; Bretylium Tosylate; Disopyramide; Humans; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine | 1980 |
[Clinical pharmacology of anti-arrhythmia agents. I. Quinidine, procainamide and disopyramide].
Topics: Arrhythmias, Cardiac; Biological Availability; Disopyramide; Half-Life; Humans; Intestinal Absorption; Kinetics; Procainamide; Pyridines; Quinidine | 1981 |
Special considerations in the use of cardiovascular drugs.
Topics: Anti-Arrhythmia Agents; Anticoagulants; Cardiac Glycosides; Cardiovascular Agents; Disopyramide; Diuretics; Female; Fetus; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Propranolol; Quinidine | 1981 |
Pharmacology of commonly used antiarrhythmic drugs and comments on the use of therapeutic drug monitoring.
Topics: Anti-Arrhythmia Agents; Disopyramide; Humans; Kinetics; Lidocaine; Procainamide; Propranolol; Quinidine | 1982 |
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy.
Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Flecainide; Humans; Imidazoles; Pre-Excitation Syndromes; Propafenone; Quinidine; Sotalol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Verapamil | 1993 |
Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Bepridil; Cardiovascular Agents; Disopyramide; Female; Humans; Male; Middle Aged; Prenylamine; Procainamide; Quinidine; Risk Factors; Sex; Sotalol; Syncope; Tachycardia, Ventricular; Torsades de Pointes | 1993 |
[Antiarrhythmic treatment after reduction of atrial fibrillation by external shock].
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Disopyramide; Electric Countershock; Flecainide; Humans; Propafenone; Quinidine; Recurrence; Sotalol | 1993 |
[Atrial flutter and fibrillation].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Calcium Channel Blockers; Catheter Ablation; Clinical Trials as Topic; Disopyramide; Electric Countershock; Electrocardiography; Emergencies; Flecainide; Heart Rate; Humans; Middle Aged; Pacemaker, Artificial; Propafenone; Quinidine; Recurrence; Sotalol; Sulfonamides; Treatment Outcome; Vasodilator Agents | 2005 |
25 trial(s) available for disopyramide and quinidine
| Article | Year |
|---|---|
Clinical studies of Norpace (Part XI).
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Disopyramide; Drug Evaluation; Female; Humans; Male; Middle Aged; Parasympathetic Nervous System; Placebos; Pyridines; Quinidine; Tachycardia | 1975 |
[The effect of disopyramide phosphate in extrasystole at rest and on exercise (author's transl)].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Exercise Test; Female; Heart; Humans; Male; Middle Aged; Placebos; Pyridines; Quinidine; Rest | 1976 |
[Clinical studies of the antiarrhythmic efficacy of disopyramide phosphate (Norpace) (author's transl)].
Topics: Administration, Oral; Cardiac Complexes, Premature; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Humans; Placebos; Pyridines; Quinidine; Tachycardia, Paroxysmal | 1978 |
Clinical studies of Norpace (Part IX).
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Diarrhea; Disopyramide; Drug Eruptions; Drug Evaluation; Female; Humans; Male; Myxedema; Purpura, Thrombocytopenic; Pyridines; Quinidine; Tachycardia | 1975 |
Prevention of sudden coronary death by chronic antiarrhythmic therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Disopyramide; Drug Evaluation; Humans; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Time Factors; Ventricular Fibrillation | 1978 |
[The effect of some antiarrhythmic drugs on systolic time intervals in normal subjects (author's transl)].
Topics: Adult; Ajmaline; Anti-Arrhythmia Agents; Atenolol; Blood Pressure; Clinical Trials as Topic; Depression, Chemical; Disopyramide; Humans; Myocardial Contraction; Propiophenones; Propranolol; Quinidine; Systole; Time Factors | 1978 |
Cardiac effects of disopyramide.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Atrioventricular Node; Clinical Trials as Topic; Disopyramide; Dogs; Heart; Heart Block; Heart Conduction System; Hemodynamics; Humans; Myocardial Contraction; Pyridines; Quinidine; Rabbits | 1976 |
Disopyramide in patients with ventricular premature beats: an experimental model and preliminary results.
Topics: Adult; Aged; Arrhythmias, Cardiac; Disopyramide; Electrocardiography; Heart Ventricles; Humans; Methods; Middle Aged; Monitoring, Physiologic; Pyridines; Quinidine; Tape Recording | 1976 |
Clinical studies of Norpace. Summarizing remarks.
Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Clinical Trials as Topic; Disopyramide; Drug Evaluation; Exercise Test; Female; Heart Block; Humans; Injections, Intravenous; Male; Middle Aged; Placebos; Pyridines; Quinidine; Riboflavin | 1975 |
[Prospective course of therapy arresting attacks of atrial fibrillation in patients with preexcitation syndromes].
Topics: Adult; Aged; Aged, 80 and over; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Female; Humans; Male; Mexiletine; Middle Aged; Moricizine; Pre-Excitation Syndromes; Procainamide; Propranolol; Quinidine; Time Factors; Verapamil | 1992 |
[Comparative effectiveness of class I anti-arrhythmia drugs and the algorithms of their selection in patients with ventricular arrhythmia].
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Heart Conduction System; Heart Ventricles; Humans; Mexiletine; Middle Aged; Quinidine | 1991 |
Comparisons of efficacy and tolerance of moricizine with other antiarrhythmic agents in the treatment of chronic ventricular arrhythmias.
Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Double-Blind Method; Encainide; Female; Flecainide; Humans; Male; Moricizine; Phenothiazines; Propranolol; Quinidine; Randomized Controlled Trials as Topic | 1990 |
Discordance between ambulatory monitoring and programmed stimulation in assessing efficacy of class IA antiarrhythmic agents in patients with ventricular tachycardia.
Topics: Aged; Ambulatory Care; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Clinical Trials as Topic; Disopyramide; Electrocardiography; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Procainamide; Quinidine; Tachycardia; Time Factors; Ventricular Fibrillation | 1985 |
The role of antiarrhythmic drugs in prevention of sudden cardiac death.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Death, Sudden; Disopyramide; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Random Allocation; Tocainide | 1985 |
Combination antiarrhythmic drug therapy for ventricular tachyarrhythmias.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Heart Conduction System; Heart Ventricles; Humans; Monitoring, Physiologic; Procainamide; Quinidine; Tachycardia | 1986 |
[Comparative study of the effectiveness of allapinin in patients with frequent and stable extrasystole].
Topics: Aconitine; Aconitum; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Clinical Trials as Topic; Disopyramide; Female; Humans; Male; Mexiletine; Middle Aged; Moricizine; Phenothiazines; Placebos; Propranolol; Quinidine | 1988 |
Randomized controlled trial of prophylactic antiarrhythmic therapy in patients with inducible ventricular tachyarrhythmias after recent myocardial infarction.
Topics: Actuarial Analysis; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Electric Stimulation; Electrocardiography; Heart Ventricles; Humans; Mexiletine; Myocardial Infarction; Prognosis; Quinidine; Random Allocation | 1988 |
[Comparison of the effects of disopyramide and hydroquinidine in animals].
Topics: Animals; Anti-Arrhythmia Agents; Clinical Trials as Topic; Disopyramide; Dogs; Drug Tolerance; Electrocardiography; Heart; Heart Conduction System; Heart Rate; Hemodynamics; Injections, Intravenous; Methods; Pyridines; Quinidine | 1973 |
[Comparative study of quinidine and disopyramide in the treatment of stable ventricular extrasystole].
Topics: Adult; Aged; Cardiac Complexes, Premature; Disopyramide; Female; Heart Ventricles; Humans; Longitudinal Studies; Male; Middle Aged; Quinidine; Random Allocation | 1983 |
The efficacy of quinidine and disopyramide in the maintenance of sinus rhythm after electroconversion from atrial fibrillation. A double-blind study comparing quinidine, disopyramide and placebo.
Topics: Adolescent; Adult; Aged; Atrial Fibrillation; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Electric Countershock; Female; Humans; Male; Middle Aged; Quinidine; Random Allocation; Sinoatrial Node; Time Factors | 1984 |
Dihydroquinidine versus disopyramide: efficacy in patients with chronic stable ventricular ectopy.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Chronic Disease; Clinical Trials as Topic; Disopyramide; Electrocardiography; Female; Humans; Kinetics; Male; Middle Aged; Monitoring, Physiologic; Placebos; Quinidine | 1984 |
A randomized, double-blind, parallel group comparison of disopyramide phosphate and quinidine in patients with cardiac arrhythmias.
Topics: Administration, Oral; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Disopyramide; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Pyridines; Quinidine; Random Allocation | 1983 |
Effects on ventricular function of disopyramide, procainamide and quinidine as determined by radionuclide angiography.
Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Output; Disopyramide; Female; Heart; Hemodynamics; Humans; Male; Middle Aged; Procainamide; Quinidine; Radionuclide Imaging; Stroke Volume | 1984 |
Effects of quinidine and disopyramide on serum digoxin concentrations.
Topics: Adult; Aged; Arrhythmias, Cardiac; Digoxin; Disopyramide; Drug Interactions; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pyridines; Quinidine; Syncope | 1980 |
[Conversion of chronic atrial fibrillation or flutter with disopyramide and a verapamil-quinidine combination: a comparative study ].
Topics: Aged; Atrial Flutter; Disopyramide; Drug Combinations; Female; Humans; Male; Middle Aged; Pyridines; Quinidine; Verapamil | 1982 |
179 other study(ies) available for disopyramide and quinidine
| Article | Year |
|---|---|
Synthesis and antiarrhythmic and parasympatholytic properties of substituted phenols. 3. Modifications to the linkage region (region 3).
Topics: Animals; Anti-Arrhythmia Agents; Dogs; Guinea Pigs; In Vitro Techniques; Male; Parasympatholytics; Phenols; Structure-Activity Relationship | 1985 |
Synthesis and antiarrhythmic activity of new 1-[1-[2-[3-(alkylamino)-2-hydroxypropoxy]phenyl]vinyl]-1 H-imidazoles and related compounds.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Dogs; Guinea Pigs; Imidazoles; Mice; Propanolamines; Structure-Activity Relationship | 1984 |
Synthesis and antiarrhythmic and parasympatholytic properties of substituted phenols. 2. Amides.
Topics: Amides; Animals; Anti-Arrhythmia Agents; Chemical Phenomena; Chemistry; Dogs; Electric Stimulation; Guinea Pigs; Heart Rate; Ileum; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Parasympatholytics; Structure-Activity Relationship | 1984 |
Synthesis and antiarrhythmic activity of new [(dialkylamino)alkyl]pyridylacetamides.
Topics: Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Electrocardiography; Female; Male; Pyridines; Structure-Activity Relationship | 1983 |
Synthesis and antiarrhythmic activity of new benzofuran derivatives.
Topics: Animals; Anti-Arrhythmia Agents; Benzofurans; Dogs; Heart Rate | 1981 |
Synthesis and antiarrhythmic activity of alpha, alpha-bis[(dialkylamino)alkyl]phenylacetamides.
Topics: Acetamides; Animals; Anti-Arrhythmia Agents; Blood Pressure; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Heart Rate; Ligation; Structure-Activity Relationship | 1980 |
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship | 1993 |
Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa).
Topics: Carrier Proteins; Corticosterone; HeLa Cells; Humans; Membrane Proteins; Midazolam; Organic Cation Transporter 1; Permeability; Recombinant Proteins; Structure-Activity Relationship; Tetraethylammonium Compounds; Transfection | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of an
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic | 2021 |
[Drug therapy of tachyarrhythmias (author's transl)].
Topics: Action Potentials; Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Procainamide; Quinidine; Tachycardia; Verapamil | 1978 |
The treatment of supraventricular arrhythmias.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Digoxin; Disopyramide; Electric Countershock; Humans; Phenytoin; Procainamide; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1979 |
Preventing ventricular arrhythmias in ischemic heart disease.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Coronary Disease; Disopyramide; Humans; Lidocaine; Nitroglycerin; Procainamide; Quinidine | 1979 |
Drugs used in the care of the cardiac patient.
Topics: Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Atropine; Bretylium Tosylate; Cardiac Glycosides; Cardiovascular Diseases; Digitalis Glycosides; Disopyramide; Diuretics; Dose-Response Relationship, Drug; Humans; Isoproterenol; Lidocaine; Myocardial Contraction; Propranolol; Quinidine | 1978 |
Pharmacology update: oral antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Disopyramide; Humans; Procainamide; Quinidine | 1979 |
Treatment of arrhythmias in the Wolff-Parkinson-White syndrome.
Topics: Administration, Oral; Atrial Fibrillation; Disopyramide; Humans; Injections, Intravenous; Lidocaine; Procainamide; Pyridines; Quinidine; Tachycardia; Ventricular Fibrillation; Wolff-Parkinson-White Syndrome | 1979 |
Series on pharmacology in practice. 2. Antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Bretylium Compounds; Disopyramide; Humans; Lidocaine; Metoprolol; Procainamide; Propranolol; Quinidine; Verapamil | 1979 |
Disopyramide-induced syncope.
Topics: Arrhythmias, Cardiac; Disopyramide; Female; Humans; Pyridines; Quinidine; Syncope | 1979 |
Adverse hemodynamic effects of intravenous disopyramide compared with quinidine in conscious dogs.
Topics: Animals; Atropine; Autonomic Nervous System; Blood Pressure; Disopyramide; Dogs; Heart Rate; Hemodynamics; Injections, Intravenous; Propranolol; Pyridines; Quinidine; Stroke Volume | 1979 |
Disopyramide phosphate: is it just another quinidine.
Topics: Action Potentials; Animals; Disopyramide; Dogs; Heart; In Vitro Techniques; Lidocaine; Membrane Potentials; Papillary Muscles; Purkinje Fibers; Pyridines; Quinidine | 1978 |
How useful are serum levels of cardiac drugs?
Topics: Anti-Arrhythmia Agents; Digitalis Glycosides; Disopyramide; Heart Diseases; Humans; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine | 1978 |
Antiarrhythmic drugs: clinical pharmacology and therapeutic uses.
Topics: Acebutolol; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Humans; Kinetics; Lidocaine; Mexiletine; Oxytocin; Phenytoin; Procainamide; Propranolol; Quinidine; Verapamil | 1978 |
Liquid chromatography in the monitoring of plasma levels of antiarrhythmic drugs.
Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Chromatography, High Pressure Liquid; Disopyramide; Lidocaine; Procainamide; Quinidine | 1978 |
Cardiac dysrhythmias.
Topics: Arrhythmias, Cardiac; Disopyramide; Humans; Quinidine; Sulfinpyrazone | 1978 |
Some effects of disopyramide and its N-dealkylated metabolite on isolated nerve and cardiac muscle.
Topics: Action Potentials; Animals; Dealkylation; Disopyramide; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Lidocaine; Myocardial Contraction; Nervous System; Neural Conduction; Procainamide; Propranolol; Pyridines; Quinidine; Rats | 1978 |
Disopyramide and quinidine.
Topics: Arrhythmias, Cardiac; Disopyramide; Female; Humans; Middle Aged; Pyridines; Quinidine | 1978 |
Electrode-catheter arrhythmia induction in the selection and assessment of antiarrhythmic drug therapy for recurrent ventricular tachycardia.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Drug Evaluation; Electric Countershock; Electrocardiography; Female; Follow-Up Studies; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Monitoring, Physiologic; Phenytoin; Procainamide; Propranolol; Quinidine; Recurrence; Tachycardia | 1978 |
Recurrent sustained ventricular tachycardia 3. Role of the electrophysiologic study in selection of antiarrhythmic regimens.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Drug Evaluation; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Female; Follow-Up Studies; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Phenytoin; Procainamide; Quinidine; Recurrence; Tachycardia | 1978 |
Treatment of cardiac arrhythmias. Part II--The drugs.
Topics: Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Electric Countershock; Humans; Lidocaine; Pacemaker, Artificial; Phenytoin; Procainamide; Propranolol; Quinidine | 1978 |
Atypical ventricular tachycardia as a manifestation of disopyramide toxicity.
Topics: Administration, Oral; Cardiac Pacing, Artificial; Disopyramide; Electrocardiography; Female; Heart Conduction System; Humans; Middle Aged; Procainamide; Propranolol; Pyridines; Quinidine; Tachycardia | 1978 |
Resistant ventricular tachycardias and recurrent cardiac arrests. 96 episodes.
Topics: Aged; Disopyramide; Electric Countershock; Heart Aneurysm; Humans; Male; Myocardial Infarction; Propranolol; Quinidine; Recurrence; Tachycardia; Ventricular Fibrillation | 1977 |
[Sino-atrial conduction time].
Topics: Ajmaline; Disopyramide; Heart Conduction System; Humans; Phenytoin; Quinidine; Time Factors; Verapamil | 1977 |
Prevention of ventricular arrhythmias after myocardial infarction.
Topics: Disopyramide; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Procainamide; Propranolol; Quinidine; Ventricular Fibrillation | 1977 |
[Disopyramide phosphate: electrophysiological and inotropic effects in isolated cat papillary muscles and comparison with quinidine (author's transl)].
Topics: Action Potentials; Animals; Cats; Disopyramide; Female; Male; Membrane Potentials; Myocardial Contraction; Papillary Muscles; Pyridines; Quinidine; Refractory Period, Electrophysiological | 1976 |
Some 10-substituted 5-ethyl-10-dialkylaminoalkyl-10,11-dihydro-5H-dibenz[b,f]azepines as potential antiarrhythmic agents.
Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Coronary Vessels; Dibenzazepines; Disopyramide; Dogs; Female; In Vitro Techniques; Ligation; Male; Ouabain; Quinidine; Rabbits; Structure-Activity Relationship | 1976 |
The electrophysiology of Norpace (Part I).
Topics: Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Bundle of His; Disopyramide; Drug Evaluation, Preclinical; Electrocardiography; Heart Conduction System; Microelectrodes; Purkinje Fibers; Pyridines; Quinidine; Rabbits | 1975 |
The electrophysiology of Norpace (Part II).
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrioventricular Node; Disopyramide; Drug Evaluation; Heart Atria; Heart Block; Heart Conduction System; Humans; Pyridines; Quinidine | 1975 |
The pharmacology of Norpace.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Atrioventricular Node; Autonomic Nervous System; Chemical Phenomena; Chemistry; Disopyramide; Dogs; Drug Evaluation, Preclinical; Electrocardiography; Heart Conduction System; Hemodynamics; Injections, Intravenous; Myocardial Infarction; Purkinje Fibers; Pyridines; Quinidine | 1975 |
Mechanism of action of antidysrhythmic drugs on ventricular conduction as studied with intramural electrodes.
Topics: Ajmaline; Animals; Disopyramide; Dogs; Electrocardiography; Heart Conduction System; Hydroxyzine; Lidocaine; Oxprenolol; Phenytoin; Propranolol; Purkinje Fibers; Quinidine; Verapamil | 1975 |
[Indications and surveillance of quinidine and disopyramide treatments].
Topics: Arrhythmias, Cardiac; Disopyramide; Humans; Pyridines; Quinidine | 1975 |
[Clinical and echocardiographic evaluation of the effects of atrial defibrillation in patients with idiopathic cardiomyopathy].
Topics: Adult; Atrial Fibrillation; Blood Pressure; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiography; Electric Countershock; Female; Heart Rate; Humans; Male; Middle Aged; Quinidine; Ventricular Function, Left | 1992 |
Combined class I antiarrhythmic agents have differential effects on tonic and use dependent block of maximum rate of depolarisation of action potentials in guinea pig cardiac muscle.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Aprindine; Disopyramide; Drug Combinations; Guinea Pigs; Lidocaine; Mexiletine; Myocardium; Quinidine; Sodium Channels | 1992 |
Sodium channel states control binding and unbinding behaviour of antiarrhythmic drugs in cardiac myocytes from the guinea pig.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Disopyramide; Dose-Response Relationship, Drug; Guinea Pigs; Myocardium; Quinidine; Sodium Channels; Time Factors | 1992 |
Voltage-dependent modification of Vmax recovery from use-dependent block by pirmenol in guinea pig papillary muscles: comparison with other class I drugs.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Flecainide; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Mexiletine; Microelectrodes; Neuromuscular Depolarizing Agents; Papillary Muscles; Piperidines; Propylamines; Pyridines; Quinidine; Sodium Channels | 1992 |
Correlation between the inhibitory effects of basic drugs on the uptake of cardiac glycosides and taurocholate by isolated rat hepatocytes.
Topics: Animals; Chlorpromazine; Dipyridamole; Disopyramide; Drug Interactions; In Vitro Techniques; Lidocaine; Liver; Male; Nifedipine; Ouabain; Propranolol; Quinidine; Rats; Rats, Wistar; Sodium; Taurocholic Acid; Verapamil | 1992 |
Mechanisms of the anticholinergic effect of SUN 1165 in comparison with flecainide, disopyramide and quinidine in single atrial myocytes isolated from guinea-pig.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Disopyramide; Flecainide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Myocardium; Parasympatholytics; Potassium Channels; Quinidine; Receptors, Cholinergic | 1991 |
Differential effect of class 1A antiarrhythmic drugs on the relationship between electrical and electromechanical systole.
Topics: Disopyramide; Electrocardiography; Humans; Procainamide; Quinidine; Systole | 1991 |
Negative inotropic effects of tetrodotoxin and seven class 1 antiarrhythmic drugs in relation to sodium channel blockade.
Topics: Action Potentials; Androstanols; Animals; Anti-Arrhythmia Agents; Aprindine; Calcium; Depression, Chemical; Disopyramide; Dose-Response Relationship, Drug; Female; Guinea Pigs; Ion Channels; Isoquinolines; Kinetics; Male; Membrane Potentials; Mexiletine; Microelectrodes; Myocardial Contraction; Myocardium; Potassium; Quinidine; Sodium; Sodium-Potassium-Exchanging ATPase; Sparteine; Tetrodotoxin | 1986 |
Proarrhythmic effects of antiarrhythmic drugs during programmed ventricular stimulation in patients without ventricular tachycardia.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Disopyramide; Female; Heart Diseases; Humans; Male; Middle Aged; Procainamide; Prospective Studies; Quinidine; Tachycardia | 1987 |
Transient increase in the contractile force induced by antiarrhythmic drugs in guinea pig cardiac muscles.
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Disopyramide; Guinea Pigs; Imidazoles; In Vitro Techniques; Myocardial Contraction; Quinidine | 1989 |
Circulatory and myocardial effects of different sodium antagonistic drugs in comparison to the calcium antagonist verapamil.
Topics: Animals; Cardiac Output; Disopyramide; Flecainide; Heart; Hemodynamics; In Vitro Techniques; Injections, Intravenous; Male; Quinidine; Rats; Rats, Inbred Strains; Sodium; Verapamil | 1989 |
Antiarrhythmic drug therapy (Part 1). Benefits and hazards.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Electrocardiography; Electrophysiology; Heart; Humans; Lidocaine; Procainamide; Quinidine | 1985 |
Anti-cholinergic effects of quinidine, disopyramide, and procainamide in isolated atrial myocytes: mediation by different molecular mechanisms.
Topics: Animals; Biomechanical Phenomena; Disopyramide; Guanosine Triphosphate; Guinea Pigs; Heart; In Vitro Techniques; Myocardium; Parasympatholytics; Potassium Channels; Procainamide; Quinidine; Receptors, Muscarinic; Receptors, Purinergic | 1989 |
Failure of corticosteroid therapy to prevent induction of ventricular tachycardia in sarcoidosis.
Topics: Adult; Amiodarone; Cardiac Pacing, Artificial; Cardiomyopathies; Disopyramide; Drug Therapy, Combination; Electrophysiology; Fluocortolone; Humans; Male; Mexiletine; Quinidine; Sarcoidosis; Tachycardia | 1989 |
[Anti-arrhythmia efficacy of propafenone per os in the prevention of paroxysmal supraventricular arrhythmia resistant to class Ia agents].
Topics: Administration, Oral; Aged; Disopyramide; Drug Evaluation; Drug Resistance; Female; Humans; Male; Middle Aged; Propafenone; Quinidine; Tachycardia, Paroxysmal; Tachycardia, Supraventricular | 1989 |
[Effects of disopyramide and quinidine on action potentials of canine ventricular myocardium and Purkinje fibers after myocardial infarction].
Topics: Action Potentials; Animals; Disopyramide; Dogs; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Myocardial Infarction; Purkinje Fibers; Quinidine | 1987 |
Simultaneous liquid-chromatographic determination of five antiarrhythmic drugs and their major active metabolites in serum.
Topics: Anti-Arrhythmia Agents; Buffers; Chromatography, High Pressure Liquid; Disopyramide; Ethylamines; Heart Diseases; Humans; Hydrogen-Ion Concentration; Lidocaine; Procainamide; Quinidine; Temperature; Tocainide | 1986 |
Orthostatic hypotension: clinical spectrum and approach to treatment.
Topics: Adult; Aged; Amiodarone; Disopyramide; Female; Flecainide; Humans; Hypotension, Orthostatic; Lidocaine; Male; Middle Aged; Piperidines; Procainamide; Quinidine; Sympathomimetics; Tocainide | 1986 |
Metabolites of antiarrhythmic drugs: are they clinically important?
Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Procainamide; Quinidine | 1986 |
Negative inotropic effect of class-I-antiarrhythmic drugs: comparison of flecainide with disopyramide and quinidine.
Topics: Animals; Cardiac Volume; Depression, Chemical; Disopyramide; Flecainide; Male; Myocardial Contraction; Pressure; Quinidine; Rats; Rats, Inbred Strains | 1987 |
Electrophysiological effects of melperone on isolated rabbit heart muscles.
Topics: Action Potentials; Animals; Butyrophenones; Disopyramide; Electric Stimulation; Electrophysiology; Female; Heart; In Vitro Techniques; Kinetics; Male; Potassium; Quinidine; Rabbits; Refractory Period, Electrophysiological | 1988 |
Long-term efficacy of mexiletine alone and in combination with class Ia antiarrhythmic drugs for refractory ventricular arrhythmias.
Topics: Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Mexiletine; Middle Aged; Procainamide; Quinidine; Tachycardia; Time Factors | 1988 |
Chronic atrial fibrillation. Long-term results of direct current conversion.
Topics: Adult; Aged; Atrial Fibrillation; Chronic Disease; Disopyramide; Electric Countershock; Female; Follow-Up Studies; Humans; Male; Middle Aged; Quinidine; Retrospective Studies; Time Factors | 1988 |
Analysis of antiarrhythmic drug concentrations determined during electrophysiologic drug testing in patients with inducible tachycardias.
Topics: Anti-Arrhythmia Agents; Disopyramide; Electric Stimulation; Electrophysiology; Humans; Procainamide; Quinidine; Tachycardia; Tachycardia, Supraventricular | 1988 |
[Experimental studies of the hemodynamics of disopyramide in comparison with quinidine].
Topics: Animals; Disopyramide; Dose-Response Relationship, Drug; Hemodynamics; Infusions, Intravenous; Quinidine; Rats; Rats, Inbred Strains | 1988 |
Clinical characteristics of patients with ventricular fibrillation during antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitalis Glycosides; Disopyramide; Diuretics; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Middle Aged; Procainamide; Quinidine; Recurrence; Retrospective Studies; Stroke Volume; Ventricular Fibrillation | 1988 |
Procainamide, disopyramide and quinidine: discordant antiarrhythmic effects during crossover comparison in patients with inducible ventricular tachycardia.
Topics: Adult; Aged; Disopyramide; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Male; Middle Aged; Procainamide; Quinidine; Tachycardia; Ventricular Fibrillation | 1987 |
Effects of intravenous disopyramide and quinidine on normal myocardium and on the characteristics of arrhythmias: intraindividual comparison in patients with sustained ventricular tachycardia.
Topics: Adult; Aged; Aged, 80 and over; Cardiac Pacing, Artificial; Coronary Disease; Disopyramide; Electrocardiography; Female; Heart Aneurysm; Heart Ventricles; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Quinidine; Tachycardia; Ventricular Fibrillation | 1987 |
Intolerance and ineffectiveness of mexiletine in patients with serious ventricular arrhythmias.
Topics: Cardiac Pacing, Artificial; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Female; Humans; Male; Mexiletine; Middle Aged; Monitoring, Physiologic; Nausea; Procainamide; Propylamines; Quinidine; Recurrence; Tachycardia; Tremor; Ventricular Fibrillation | 1986 |
[Three cases of torsades de pointes due to anti-arrhythmic agents].
Topics: Aged; Aged, 80 and over; Disopyramide; Electrocardiography; Female; Humans; Middle Aged; Procainamide; Quinidine; Tachycardia | 1986 |
Idiopathic ventricular fibrillation: inducibility and beneficial effects of class I antiarrhythmic agents.
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiac Pacing, Artificial; Disopyramide; Drug Evaluation; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Quinidine; Ventricular Fibrillation | 1987 |
Effect of myocardial ischemia and type I antiarrhythmic drug therapy on exercise QT intervals.
Topics: Anti-Arrhythmia Agents; Coronary Disease; Disopyramide; Electrocardiography; Exercise Test; Heart Conduction System; Humans; Long QT Syndrome; Male; Middle Aged; Procainamide; Quinidine | 1985 |
The usefulness of electrophysiological-pharmacologic studies in the long-term therapy of paroxysmal tachycardias.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathies; Chromatography, High Pressure Liquid; Disopyramide; Electric Stimulation; Electrocardiography; Female; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Myocardial Infarction; Propafenone; Propiophenones; Quinidine; Tachycardia, Paroxysmal; Time Factors; Tocainide; Verapamil | 1985 |
Aggravation of ventricular arrhythmia. A drug-induced complication.
Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine | 1985 |
Haemodynamic effects of class I antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Disopyramide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide | 1985 |
[Anti-arrhythmia agents (I): Quinidine, procainamide, disopyramide, encainide, propafenone and flecainide].
Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine | 1985 |
[Panel discussion: Evaluation of the antiarrhythmic drugs and current problems associated with their use in clinical practice (author's transl)].
Topics: Administration, Oral; Ajmaline; Aniline Compounds; Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Diethylamines; Disopyramide; Dogs; Heart Ventricles; Humans; Indans; Injections; Injections, Intravenous; Myocardial Infarction; Practolol; Procainamide; Propranolol; Quinidine; Tachycardia | 1974 |
Cardiovascular effects of a newer antiarrhythmic agent, disopyramide phosphate.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiomegaly; Catheterization; Coronary Circulation; Disopyramide; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Femoral Artery; Femoral Vein; Heart; Heart Rate; Hemodynamics; Humans; Isoproterenol; Male; Norepinephrine; Pyridines; Quinidine; Tyramine | 1972 |
Synthesis and antiarrhythmic activity of 5,5-disubstituted-3-aminoalkylhydantions and some heterocyclic and noncyclic analogues.
Topics: Alkylation; Amides; Animals; Arrhythmias, Cardiac; Diethylamines; Dimethylamines; Disopyramide; Heterocyclic Compounds; Hydantoins; Isomerism; Mice; Piperidines; Quinidine; Structure-Activity Relationship; Urea; Ventricular Fibrillation | 1974 |
Comparative binding of disopyramide phosphate and quinidine sulfate to human plasma proteins.
Topics: Binding Sites; Binding, Competitive; Blood Proteins; Disopyramide; Humans; In Vitro Techniques; Organophosphorus Compounds; Protein Binding; Pyridines; Quinidine; Serum Albumin; Solubility; Spectrophotometry, Ultraviolet; Sulfuric Acids | 1974 |
[Electrophysiological principles of the action of antiarrhythmia agents].
Topics: Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Electrophysiology; Heart; Humans; Lidocaine; Procainamide; Quinidine | 1974 |
[Comparison of the effects of quinidine, diphenylhydantoin and disopyramide on the auricular refractory period in the anesthetized dog].
Topics: Animals; Atrial Function; Disopyramide; Dogs; Electric Stimulation; Female; Heart Atria; Heart Block; Male; Neural Conduction; Phenytoin; Pyridines; Quinidine; Refractory Period, Electrophysiological | 1974 |
[Toxic and hemodynamic effects of aprindine in the dog. Comparison with other anti-arrhythmia agents].
Topics: Ajmaline; Aniline Compounds; Animals; Anti-Arrhythmia Agents; Aorta; Blood Pressure; Cardiac Output; Diethylamines; Disopyramide; Dogs; Heart Rate; Heart Ventricles; Hemodynamics; Indans; Indenes; Injections, Intravenous; Phenytoin; Procainamide; Pulmonary Artery; Quinidine; Respiration; Vascular Resistance | 1974 |
Effects of disopyramide on electrophysiological and mechanical properties of the heart.
Topics: Action Potentials; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Catheterization; Disopyramide; Electric Stimulation; Electrocardiography; Heart Conduction System; Heart Rate; Heart Ventricles; Membrane Potentials; Papillary Muscles; Pyridines; Quinidine; Sinoatrial Node; Time Factors | 1973 |
[Anti-arrhythmic action of disopyramide in comparison with that of quinidine].
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Pyridines; Quinidine | 1971 |
Drugs and the heart. IV. Antiarrhythmic agents.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Heart Conduction System; Hemodynamics; Humans; Lidocaine; Mexiletine; Procainamide; Quinidine; Verapamil | 1980 |
[Effects of anti-arrhythmia agents on heart rate. Significance and importance].
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Disopyramide; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Lidocaine; Propafenone; Propiophenones; Quinidine; Verapamil | 1981 |
Antiarrhythmic drugs.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide; Verapamil | 1983 |
[Pharmacotherapy of paroxysmal tachycardia].
Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Atrial Flutter; Digitalis Glycosides; Disopyramide; Heart Failure; Humans; Quinidine; Tachycardia, Paroxysmal; Verapamil | 1983 |
[Pharmacological treatment of arrhythmia].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Disopyramide; Drug Evaluation; Heart Conduction System; Humans; Procainamide; Quinidine | 1983 |
New directions in antiarrhythmic drug therapy.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil | 1984 |
Factors influencing serum protein binding of lidocaine in humans.
Topics: Acecainide; Blood Proteins; Bupivacaine; Disopyramide; Humans; Lidocaine; Orosomucoid; Procainamide; Propranolol; Protein Binding; Quinidine; Serum Albumin | 1981 |
[Effect of various anti-arrhythmia drugs on serum digoxin level].
Topics: Aged; Anti-Arrhythmia Agents; Biological Availability; Cardiac Complexes, Premature; Digoxin; Disopyramide; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Phenytoin; Procainamide; Quinidine | 1981 |
High performance liquid chromatographic analysis of the antiarrhythmic drugs procainamide, disopyramide, quinidine, propranolol and metabolites from serum extracts.
Topics: Acecainide; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Disopyramide; Humans; Procainamide; Propranolol; Pyridines; Quinidine; Spectrophotometry, Ultraviolet | 1981 |
Treatment of chronic ventricular dysrhythmias in the young.
Topics: Administration, Oral; Adolescent; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Child, Preschool; Chronic Disease; Disopyramide; Follow-Up Studies; Heart Ventricles; Hemodynamics; Humans; Infant; Infant, Newborn; Injections, Intravenous; Male; Phenytoin; Propranolol; Quinidine; Tachycardia | 1981 |
Effects of quinidine, procainamide and disopyramide on automaticity and cyclic AMP content of guinea-pig atria.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Function; Cyclic AMP; Depression, Chemical; Disopyramide; Guinea Pigs; Heart; Heart Rate; Male; Procainamide; Pyridines; Quinidine | 1981 |
Cardiac transplantation--the ideal model for electrophysiologic drug testing?
Topics: Animals; Atropine; Cardiovascular Agents; Digoxin; Disopyramide; Edrophonium; Electrophysiology; Heart; Heart Conduction System; Heart Rate; Heart Transplantation; Humans; Norepinephrine; Quinidine | 1983 |
Long-term antiarrhythmic therapy. Problem of low drug levels and patient noncompliance.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Disopyramide; Female; Heart Diseases; Humans; Male; Middle Aged; Patient Compliance; Procainamide; Quinidine; Self Administration; Time Factors | 1984 |
Potential applications of free drug level monitoring in cardiovascular therapy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Binding Sites; Blood Proteins; Cardiovascular Agents; Disopyramide; Humans; Orosomucoid; Protein Binding; Quinidine | 1984 |
Effects of 4 antiarrhythmic drugs on sinoatrial conduction time in isolated and blood-perfused dog atria.
Topics: Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Electric Stimulation; Heart Rate; In Vitro Techniques; Myocardial Contraction; Procainamide; Propranolol; Quinidine; Sinoatrial Node | 1984 |
Simultaneous analysis of antiarrhythmic drugs and metabolites by high performance liquid chromatography: interference studies and comparisons with other methods.
Topics: Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Cross Reactions; Disopyramide; Immunoenzyme Techniques; Propranolol; Quinidine | 1982 |
[Pharmacokinetics of anti-arrhythmics. 2. Clinical applications].
Topics: Administration, Oral; Anti-Arrhythmia Agents; Disopyramide; Humans; Kinetics; Lidocaine; Perfusion; Phenytoin; Procainamide; Propranolol; Quinidine | 1980 |
[Determination of plasma concentrations of anti-arrhythmia agents].
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biological Availability; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine | 1981 |
Time course of the electrophysiological effects of quinidine on canine cardiac Purkinje fibers: concentration dependence and comparison with lidocaine and disopyramide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Dose-Response Relationship, Drug; Electrophysiology; Female; Heart Conduction System; Kinetics; Lidocaine; Male; Purkinje Fibers; Quinidine | 1983 |
The response to procainamide during electrophysiologic study for sustained ventricular tachyarrhythmias predicts the response to other medications.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Female; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Phenytoin; Procainamide; Quinidine; Tachycardia | 1983 |
Concurrent use of quinidine and disopyramide: evaluation of serum concentrations and electrocardiographic effects.
Topics: Adult; Disopyramide; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Female; Heart; Humans; Male; Pyridines; Quinidine | 1983 |
Concordance and discordance of drug responses in atrioventricular reentrant tachycardia.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Atrioventricular Node; Cardiac Pacing, Artificial; Child; Disopyramide; Drug Evaluation; Drug Therapy, Combination; Electrophysiology; Female; Humans; Male; Middle Aged; Ouabain; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal | 1983 |
Inducible sustained ventricular tachycardia refractory to individual class I drugs: effect of adding a second class I drug.
Topics: Aged; Anti-Arrhythmia Agents; Disopyramide; Drug Therapy, Combination; Electric Stimulation; Electrophysiology; Female; Humans; Male; Middle Aged; Procainamide; Quinidine; Tachycardia, Paroxysmal | 1983 |
Antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digitalis Glycosides; Disopyramide; Heart Conduction System; Humans; Lidocaine; Phenytoin; Procainamide; Quinidine | 1980 |
Simultaneous liquid-chromatographic determination of three antiarrhythmic drugs: disopyramide, lidocaine, and quinidine.
Topics: Chromatography, High Pressure Liquid; Disopyramide; Drug Interactions; Fluorometry; Humans; Immunoenzyme Techniques; Lidocaine; Pyridines; Quinidine | 1980 |
Cardiac drug overdose.
Topics: Arrhythmias, Cardiac; Bretylium Compounds; Cardiovascular Agents; Cardiovascular Diseases; Digoxin; Disopyramide; Humans; Hypotension; Lidocaine; Liver; Phenytoin; Procainamide; Propranolol; Quinidine; Vasodilator Agents | 1982 |
Atypical ventricular tachycardia (torsade de pointes) induced by amiodarone: arrhythmia previously induced by quinidine and disopyramide.
Topics: Adult; Amiodarone; Atrial Fibrillation; Benzofurans; Disopyramide; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Ventricles; Humans; Prajmaline; Pyridines; Quinidine; Tachycardia | 1982 |
Investigation of digoxin, quinidine, and disopyramide interactions in rats utilizing parotid saliva, blood, and other tissues.
Topics: Animals; Digoxin; Disopyramide; Drug Interactions; Male; Pyridines; Quinidine; Rats; Rats, Inbred Strains; Saliva; Tissue Distribution | 1982 |
Electrophysiologic drug testing in prophylaxis of sporadic paroxysmal atrial fibrillation: technique, application, and efficacy in severely symptomatic preexcitation patients.
Topics: Administration, Oral; Adolescent; Adult; Aprindine; Atrial Fibrillation; Cardiac Pacing, Artificial; Disopyramide; Electrophysiology; Heart Conduction System; Humans; Male; Middle Aged; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal; Time Factors; Wolff-Parkinson-White Syndrome | 1982 |
Sustained macroreentrant ventricular tachycardia.
Topics: Aged; Amiodarone; Disopyramide; Electrocardiography; Heart Conduction System; Humans; Male; Procainamide; Quinidine; Recurrence; Tachycardia | 1982 |
Prediction of response to class I antiarrhythmic drugs during electrophysiologic study of ventricular tachycardia.
Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Electrophysiology; Female; Heart Failure; Humans; Male; Middle Aged; Procainamide; Quinidine; Regression Analysis; Syncope; Tachycardia | 1982 |
Torsades de pointes, a common arrhythmia, induced by medication.
Topics: Aged; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Female; Humans; Male; Middle Aged; Phenothiazines; Procainamide; Quinidine; Syncope; Ventricular Fibrillation | 1982 |
Simultaneous high-performance liquid chromatographic assay for quinidine, disopyramide and the mono-N-dealkylated metabolite of disopyramide.
Topics: Arrhythmias, Cardiac; Chromatography, High Pressure Liquid; Disopyramide; Humans; Pyridines; Quinidine; Reference Values | 1982 |
[Atypical ventricular tachycardia due to disopyramide].
Topics: Aged; Disopyramide; Female; Humans; Isoproterenol; Pyridines; Quinidine; Tachycardia | 1982 |
Anticholinergic effects of disopyramide and quinidine on guinea pig myocardium. Mediation by direct muscarinic receptor blockade.
Topics: Animals; Atropine; Disopyramide; Female; Guinea Pigs; Heart Atria; Male; Myocardium; Parasympatholytics; Physostigmine; Procainamide; Pyridines; Quinidine; Receptors, Muscarinic; Time Factors | 1980 |
Electrophysiological effects of the optical isomers of disopyramide and quinidine in the dog. Dependence on stereochemistry.
Topics: Action Potentials; Animals; Disopyramide; Dogs; Electrophysiology; Female; Male; Purkinje Fibers; Pyridines; Quinidine; Quinine; Stereoisomerism; Time Factors | 1981 |
Liquid-chromatographic determination of antidysrhythmic drugs: procainamide, lidocaine, quinidine, disopyramide, and propranolol.
Topics: Anti-Arrhythmia Agents; Chromatography, Liquid; Disopyramide; Humans; Lidocaine; Procainamide; Propranolol; Quinidine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1981 |
Cardiovascular drugs for the geriatric patient.
Topics: Aged; Aging; Antihypertensive Agents; Cardiovascular Agents; Cardiovascular Physiological Phenomena; Digoxin; Disopyramide; Humans; Intestinal Absorption; Kidney; Lidocaine; Phenytoin; Procainamide; Propranolol; Quinidine | 1981 |
Comments on: "anticholinergic effects of disopyramide and quinidine on guinea pig myocardium--mediation by direct muscarinic receptor blockade".
Topics: Animals; Cholinergic Antagonists; Disopyramide; Guinea Pigs; Muscarinic Antagonists; Parasympatholytics; Pyridines; Quinidine | 1981 |
Adverse reactions to cardiovascular drugs (Part II--Antiarrhythmic agents).
Topics: Anti-Arrhythmia Agents; Disopyramide; Lidocaine; Procainamide; Quinidine | 1981 |
Myocardial conduction time and antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disopyramide; Dogs; Electrophysiology; Heart Conduction System; Lidocaine; Quinidine; Ventricular Function; Verapamil | 1981 |
Torsade de pointes ventricular tachycardia. A complication of disopyramide shared with quinidine.
Topics: Aged; Disopyramide; Electrocardiography; Female; Heart Ventricles; Humans; Middle Aged; Pyridines; Quinidine; Tachycardia | 1981 |
Ventricular pacing in atypical ventricular tachycardia.
Topics: Aged; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Disopyramide; Electrocardiography; Female; Humans; Isoproterenol; Male; Quinidine; Tachycardia | 1981 |
Etiology, warning signs and therapy of torsade de pointes. A study of 10 patients.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Disopyramide; Electrocardiography; Female; Heart Ventricles; Humans; Male; Middle Aged; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Time Factors | 1981 |
[Pharmacological therapy and prevention of recurrent ventricular tachycardia].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Bunaftine; Disopyramide; Humans; Male; Middle Aged; Procainamide; Propranolol; Quinidine; Tachycardia | 1981 |
Comparison of i.v. quinidine and disopyramide.
Topics: Animals; Disopyramide; Dogs; Infusions, Parenteral; Myocardial Contraction; Pyridines; Quinidine | 1980 |
Electrophysiological effects of disopyramide and quinidine on guinea pig atria and canine cardiac purkinje fibers. Dependence on underlying cholinergic tone.
Topics: Action Potentials; Animals; Atropine; Disopyramide; Dogs; Electrophysiology; Female; Guinea Pigs; Heart Atria; Heart Conduction System; Heart Rate; Male; Parasympatholytics; Physostigmine; Procainamide; Purkinje Fibers; Pyridines; Quinidine | 1980 |
Effects of antiarrhythmic drugs on atrioventricular conduction in patients with acute myocardial infarction.
Topics: Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Digoxin; Disopyramide; Heart Block; Heart Conduction System; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Procainamide; Propranolol; Quinidine; Time Factors | 1980 |
The effect of quinidine and other oral antiarrhythmic drugs on serum digoxin. A prospective study.
Topics: Aged; Anorexia; Anti-Arrhythmia Agents; Digoxin; Disopyramide; Drug Interactions; Female; Humans; Male; Mexiletine; Middle Aged; Nausea; Procainamide; Prospective Studies; Quinidine; Vomiting | 1980 |
Simultaneous analysis of disopyramide and quinidine in plasma by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Disopyramide; Humans; Pyridines; Quinidine; Spectrophotometry, Ultraviolet | 1980 |
[Paradoxic response to disopyramide and quinidine (author's transl)].
Topics: Adult; Aged; Disopyramide; Female; Heart Valve Diseases; Humans; Male; Middle Aged; Mitral Valve; Pyridines; Quinidine; Quinine; Tachycardia; Ventricular Fibrillation | 1980 |
Efficacy of type 1C antiarrhythmic agents for treatment of resistant atrial fibrillation.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Encainide; Female; Flecainide; Heart Rate; Humans; Male; Middle Aged; Procainamide; Propafenone; Quinidine; Recurrence; Retrospective Studies | 1993 |
Quinidine but not disopyramide prolongs cardiac Purkinje fiber action potentials after a pause.
Topics: Action Potentials; Animals; Disopyramide; Dogs; Dose-Response Relationship, Drug; Electrodes, Implanted; In Vitro Techniques; Purkinje Fibers; Quinidine; Torsades de Pointes | 1994 |
Antiarrhythmic and bradycardic drugs inhibit currents of cloned K+ channels, KV1.2 and KV1.4.
Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Cloning, Molecular; Disopyramide; Dose-Response Relationship, Drug; Mathematics; Oocytes; Potassium Channels; Quaternary Ammonium Compounds; Quinidine; Verapamil; Xenopus laevis | 1995 |
Action potential prolongation exhibits simple dose-dependence for sotalol, but reverse dose-dependence for quinidine and disopyramide: implications for proarrhythmia due to triggered activity.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cesium; Disopyramide; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Microelectrodes; Purkinje Fibers; Quinidine; Sotalol | 1993 |
Voltage-dependent inhibition of the ATP-sensitive K+ current by the class Ia agent disopyramide in cat ventricular myocytes.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Cats; Disopyramide; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Myocardial Ischemia; Potassium Channel Blockers; Quinidine | 1995 |
Open Na+ channel blockade: multiple rest states revealed by channel interactions with disopyramide and quinidine.
Topics: Animals; Disopyramide; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Ion Channel Gating; Kinetics; Mathematics; Membrane Potentials; Quinidine; Rabbits; Sodium Channel Blockers; Sodium Channels | 1994 |
Effects of hyperkalaemia on the depression of maximum rate of depolarization by class I antiarrhythmic agents in guinea-pig myocardium.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Female; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Male; Mexiletine; Microelectrodes; Potassium; Quinidine | 1993 |
Differential effects of antiarrhythmic agents on post-pause repolarization in cardiac Purkinje fibres.
Topics: Action Potentials; Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Dose-Response Relationship, Drug; Phenethylamines; Potassium Channels; Purkinje Fibers; Quaternary Ammonium Compounds; Quinidine; Sodium Channels; Sotalol; Sulfonamides | 1996 |
Mechanisms of the atrium-specific positive inotropic activities of quinidine- and atropine-like agents in rats.
Topics: Animals; Anti-Arrhythmia Agents; Atropine; Bupivacaine; Catecholamines; Dimethylphenylpiperazinium Iodide; Disopyramide; Heart Atria; Isoproterenol; Male; Myocardial Contraction; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stimulation, Chemical | 1997 |
Amiodarone inhibits production of tumor necrosis factor-alpha by human mononuclear cells: a possible mechanism for its effect in heart failure.
Topics: Amiodarone; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Heart Failure; Humans; Interleukin-1; Interleukin-6; Lidocaine; Monocytes; Osmolar Concentration; Quinidine; Tumor Necrosis Factor-alpha | 1997 |
[Can 1/1 atrial flutter be foreseen by class I anti-arrhythmics?].
Topics: Aged; Anti-Arrhythmia Agents; Atrial Flutter; Disopyramide; Electrocardiography; Female; Flecainide; Heart Conduction System; Humans; Imidazoles; Male; Middle Aged; Predictive Value of Tests; Propafenone; Quinidine; Risk Factors | 1997 |
Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle.
Topics: Animals; Anti-Arrhythmia Agents; Aorta; Desipramine; Disopyramide; Flecainide; Imipramine; In Vitro Techniques; Lidocaine; Male; Mexiletine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Quinidine; Rats; Rats, Sprague-Dawley | 1997 |
Idiopathic ventricular fibrillation: is there a role for electrophysiologic-guided antiarrhythmic drug therapy?
Topics: Anti-Arrhythmia Agents; Disopyramide; Echocardiography; Humans; Procainamide; Quinidine; Ventricular Fibrillation | 1999 |
Comparison of the effect of class IA antiarrhythmic drugs on transmembrane potassium currents in rabbit ventricular myocytes.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Delayed Rectifier Potassium Channels; Disopyramide; Female; In Vitro Techniques; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Potassium Channels, Voltage-Gated; Procainamide; Quinidine; Rabbits | 2003 |
Characterisation of recombinant HERG K+ channel blockade by the Class Ia antiarrhythmic drug procainamide.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cell Line; Cell Membrane; Disopyramide; DNA-Binding Proteins; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Inhibitory Concentration 50; Long QT Syndrome; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Procainamide; Quinidine; Time Factors; Trans-Activators; Transcriptional Regulator ERG | 2003 |
Interaction of quinidine, disopyramide and metoprolol with melanin in vitro in relation to drug-induced ocular toxicity.
Topics: Anti-Arrhythmia Agents; Binding Sites; Dihydroxyphenylalanine; Disopyramide; Eye Diseases; Kinetics; Melanins; Metoprolol; Quinidine; Spectrophotometry, Ultraviolet | 2003 |
A COMPARISON OF THE ANTIFIBRILLATORY ACTIONS AND EFFECTS ON INTRACELLULAR CARDIAC POTENTIALS OF PRONETHALOL, DISOPYRAMIDE AND QUINIDINE.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Electrophysiology; Ethanolamines; Heart; Heart Atria; Pharmacology; Quinidine; Rabbits; Research; Sympatholytics | 1963 |
Atrial fibrillation: rate control often better than rhythm control.
Topics: Adult; Aged; Amiodarone; Anticoagulants; Arrhythmia, Sinus; Atrial Fibrillation; Canada; Disopyramide; Electric Countershock; Flecainide; Heart Rate; Humans; Netherlands; Platelet Aggregation Inhibitors; Propafenone; Quinidine; Sotalol; United States | 2004 |
Human organic cation transporter 3 mediates the transport of antiarrhythmic drugs.
Topics: Animals; Anti-Arrhythmia Agents; Biological Transport; Cell Line; Disopyramide; Dose-Response Relationship, Drug; Histamine; Humans; Lidocaine; Mice; Organic Cation Transport Proteins; Phenytoin; Procainamide; Quinidine | 2004 |
In vivo effects of mutant HERG K+ channel inhibition by disopyramide in patients with a short QT-1 syndrome: a pilot study.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diarrhea; Disopyramide; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Exercise Test; Female; Humans; Mutation; Pilot Projects; Quinidine; Treatment Outcome | 2007 |
High efficacy of disopyramide in the management of ventricular fibrillation storms in a patient with Brugada syndrome.
Topics: Anti-Arrhythmia Agents; Brugada Syndrome; Defibrillators, Implantable; Disopyramide; Electrocardiography; Humans; Male; Middle Aged; Quinidine; Ventricular Fibrillation | 2010 |
Pharmacological prevention and termination of focal atrial fibrillation.
Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Atrial Appendage; Atrial Fibrillation; Disopyramide; Dogs; Drug Therapy, Combination; Pulmonary Veins; Quinidine; Sodium Channel Blockers | 2012 |
In silico assessment of the effects of quinidine, disopyramide and E-4031 on short QT syndrome variant 1 in the human ventricles.
Topics: Action Potentials; Arrhythmias, Cardiac; Cell Line; Disopyramide; Electrocardiography; ERG1 Potassium Channel; Heart Ventricles; Humans; Models, Biological; Piperidines; Polymorphism, Single Nucleotide; Pyridines; Quinidine | 2017 |
Modelling the effects of quinidine, disopyramide, and E-4031 on short QT syndrome variant 3 in the human ventricles.
Topics: Action Potentials; Arrhythmias, Cardiac; Disopyramide; Heart Conduction System; Heart Defects, Congenital; Heart Ventricles; Humans; Models, Biological; Piperidines; Pyridines; Quinidine | 2017 |
Theophylline as an adjunct to control malignant ventricular arrhythmia associated with early repolarization.
Topics: Anti-Arrhythmia Agents; Child; Defibrillators, Implantable; Disopyramide; Humans; Male; Quinidine; Recurrence; Tachycardia, Ventricular; Theophylline; Vasodilator Agents | 2018 |
In Silico Assessment of Class I Antiarrhythmic Drug Effects on
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Computer Simulation; Disopyramide; Heart Atria; Homeobox Protein PITX2; Homeodomain Proteins; Humans; Mice; Propafenone; Quinidine; Transcription Factors | 2021 |