disopyramide has been researched along with metoprolol in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.00) | 18.7374 |
| 1990's | 8 (26.67) | 18.2507 |
| 2000's | 12 (40.00) | 29.6817 |
| 2010's | 7 (23.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Jolivette, LJ; Ward, KW | 1 |
| Jolivette, LJ; Nagilla, R; Ward, KW | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Federman, J; Vlietstra, RE | 1 |
| Korsukewitz, J; Schmutzler, H; Wegscheider, K | 1 |
| Delise, P; Di Pede, F; Piccolo, E; Raviele, A | 1 |
| Carlsson, B; Drvota, V; Häggblad, J; Sylvén, C | 1 |
| Grubb, BP; Kip, K; Kosinski, D; Lorton, M; Pothoulakis, A; Samoil, D | 1 |
| Camm, AJ; Frenneaux, MP; McKenna, WJ; Scalia, G; Sneddon, JF; Ward, DE | 1 |
| Bobrov, VA; Frolov, AI; Galichansky, IV; Mitchenko, EI | 1 |
| Akhtar, M; Avitall, B; Blanck, Z; Deshpande, S; Dhala, A; Jazayeri, MR; Sra, JS | 1 |
| Cobbe, SM; Cooper, JP; Pentousis, D | 1 |
| Auld, D; Benson, DW; Campbell, R; Deal, BJ; Hulse, E; Scagliotti, D; Strasburger, JF; Strieper, M | 1 |
| Horvat, M; Pernat, A; Pohar, B | 1 |
| Durkin, D; Foley, JP | 1 |
| Buszman, E; Rózańska, R | 1 |
1 review(s) available for disopyramide and metoprolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for disopyramide and metoprolol
| Article | Year |
|---|---|
[Idiopathic ventricular tachyarrhythmia. Spontaneous variability and effect of various antiarrhythmic agents].
Topics: Adult; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Clinical Trials as Topic; Disopyramide; Dose-Response Relationship, Drug; Drug Evaluation; Electrocardiography; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Propafenone; Propiophenones; Tachycardia | 1985 |
28 other study(ies) available for disopyramide and metoprolol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution | 2005 |
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human.
Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Series on pharmacology in practice. 2. Antiarrhythmic drug therapy.
Topics: Anti-Arrhythmia Agents; Bretylium Compounds; Disopyramide; Humans; Lidocaine; Metoprolol; Procainamide; Propranolol; Quinidine; Verapamil | 1979 |
[Value of a serial electropharmacologic study in survivors of a cardiac arrest secondary to ventricular tachycardia or ventricular fibrillation].
Topics: Adult; Aged; Amiodarone; Death, Sudden; Disopyramide; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Heart Arrest; Humans; Male; Metoprolol; Middle Aged; Pindolol; Propafenone; Propiophenones; Tachycardia; Ventricular Fibrillation | 1984 |
Amiodarone is a dose-dependent noncompetitive and competitive inhibitor of T3 binding to thyroid hormone receptor subtype beta 1, whereas disopyramide, lignocaine, propafenone, metoprolol, dl-sotalol, and verapamil have no inhibitory effect.
Topics: Amiodarone; Anti-Arrhythmia Agents; Binding, Competitive; Disopyramide; Dose-Response Relationship, Drug; Humans; Lidocaine; Metoprolol; Propafenone; Receptors, Thyroid Hormone; Sotalol; Triiodothyronine; Verapamil | 1995 |
Postpartum syncope.
Topics: 1-Naphthylamine; Administration, Oral; Adolescent; Adult; Diagnosis, Differential; Disopyramide; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fludrocortisone; Humans; Hypotension; Metoprolol; Puerperal Disorders; Selective Serotonin Reuptake Inhibitors; Sertraline; Syncope; Tilt-Table Test | 1995 |
Exercise induced vasodepressor syncope.
Topics: Adolescent; Adult; Aged; Cardiac Output; Disopyramide; Exercise; Exercise Test; Female; Heart Rate; Humans; Hypotension; Hypotension, Orthostatic; Male; Metoprolol; Syncope; Vascular Resistance | 1994 |
Comparative analysis of electrophysiologic effect of metoprolol and disopyramide, acting alone or in combination in patients with supraventricular tachycardia and Wolff-Parkinson-White syndrome.
Topics: Adult; Disopyramide; Drug Therapy, Combination; Electrophysiology; Female; Humans; Male; Metoprolol; Tachycardia, Supraventricular; Wolff-Parkinson-White Syndrome | 1994 |
Comparison of cardiac pacing with drug therapy in the treatment of neurocardiogenic (vasovagal) syncope with bradycardia or asystole.
Topics: Adolescent; Adult; Aged; Bradycardia; Cardiac Pacing, Artificial; Disopyramide; Female; Follow-Up Studies; Heart Arrest; Humans; Hypotension; Male; Metoprolol; Middle Aged; Posture; Recurrence; Syncope; Theophylline | 1993 |
Prolonged asystole induced by head up tilt test. Report of four cases and brief review of the prognostic significance and medical management.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Disopyramide; Female; Heart Arrest; Humans; Male; Metoprolol; Middle Aged; Prognosis; Syncope, Vasovagal; Tilt-Table Test | 1997 |
The medical therapy of cardioinhibitory syncope in pediatric patients.
Topics: Adrenergic Agonists; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Child; Cohort Studies; Disopyramide; Drug Combinations; Ephedrine; Fludrocortisone; Fluid Therapy; Follow-Up Studies; Heart Arrest; Humans; Incidence; Metoprolol; Pacemaker, Artificial; Recurrence; Safety; Sodium Chloride, Dietary; Syncope, Vasovagal; Tilt-Table Test; Time Factors; Treatment Outcome; Treatment Refusal | 1997 |
Heart conduction disturbances and cardiovascular collapse after disopyramide and low-dose metoprolol in a patient with hypertrophic obstructive cardiomyopathy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiomyopathy, Hypertrophic; Disopyramide; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Humans; Male; Metoprolol; Middle Aged; Shock | 1997 |
Dual-opposite injection electrokinetic chromatography for the unbiased, simultaneous separation of cationic and anionic compounds.
Topics: Anions; Benzoates; Bupivacaine; Cations; Chromatography; Disopyramide; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Metoprolol; Sensitivity and Specificity; Surface-Active Agents | 2000 |
Interaction of quinidine, disopyramide and metoprolol with melanin in vitro in relation to drug-induced ocular toxicity.
Topics: Anti-Arrhythmia Agents; Binding Sites; Dihydroxyphenylalanine; Disopyramide; Eye Diseases; Kinetics; Melanins; Metoprolol; Quinidine; Spectrophotometry, Ultraviolet | 2003 |