disopyramide and atropine

disopyramide has been researched along with atropine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199018 (47.37)18.7374
1990's6 (15.79)18.2507
2000's8 (21.05)29.6817
2010's6 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Both, A; Breithardt, G; Höhfeld, E; Loogen, F; Seipel, L1
Landmark, K; Storstein, O1
Coma Canella, I; García Fernández, F; González Maqueda, I; López Sendon, JL; Martin Jadraque, L1
Horwitz, LD; Walsh, RA1
Birkhead, JS; Vaughan Williams, EM1
Both, A; Breithardt, G; Loogen, F; Seipel, L1
Boucher, M; Cazes, M; Chassaing, C; Cloarec, A; Duchêne-Marullaz, P; Martinet, M; Provost, D1
Fujiwara, M; Ishida, Y; Mizukami, M; Satake, N; Shibata, S; Taniguchi, T1
Brembilla-Perrot, B; Vaur, L1
Antiu'fev, VF; Arkhipov, MV1
Barvais, L; Baurain, M; d'Hollander, A; Hennart, D1
Augsten, G; Pfeiffer, D; Rathgen, K; Rostock, KJ1
Aaltonen, L; Iisalo, E1
Bexton, RS; Camm, AJ1
Jordan, J; Karagueuzian, HS; Katoh, T; Mandel, WJ1
Bailey, JC; Manalan, AS; Mirro, MJ; Watanabe, AM1
Marshall, RJ; Muir, AW; Winslow, E1
Godin, D; Guimond, C; LeBlanc, RA; Nadeau, R; Pelletier, B1
Bailey, JC; Mirro, MJ; Watanabe, AM1
Kashani, IA; Shakibi, JG; Siassi, B1
Eichler, HG; Gouya, G; Schmetterer, L; Wolzt, M; Zanaschka, G1
Chemtob, S; Deng, XF; Mulay, S; Varma, DR1
Camm, AJ; de Jonghe, D; Debbas, NM; Jackson, SH; Robert, A1
Elliott, RA; Hudman, D; Norman, RI; Sandhu, D; Terry, T1

Reviews

2 review(s) available for disopyramide and atropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Efficacy and tolerance of disopyramide in arrhythmia associated with sinus node dysfunction].
    Archives des maladies du coeur et des vaisseaux, 1991, Volume: 84, Issue:6

    Topics: Aged; Arrhythmias, Cardiac; Atropine; Bradycardia; Disopyramide; Electrocardiography, Ambulatory; Electrophysiology; Female; Humans; Male; Middle Aged; Sinoatrial Block; Sinoatrial Node

1991

Trials

2 trial(s) available for disopyramide and atropine

ArticleYear
[The effect of drugs on "sino-atrial conduction time" and on sinus-node automaticity in man].
    Zeitschrift fur Kardiologie, 1975, Volume: 64, Issue:10

    Topics: Atropine; Bundle of His; Cardiac Catheterization; Cardiac Complexes, Premature; Disopyramide; Electric Stimulation; Electrocardiography; Heart Atria; Heart Rate; Humans; Propiophenones; Pyridines; Sinoatrial Node; Stimulation, Chemical; Time Factors

1975
Is the ECG measure RSh a promising technique for detecting class I antiarrhythmic drug action in men?
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: Adenosine; Adult; Ajmaline; Anti-Arrhythmia Agents; Atropine; Disopyramide; Electrocardiography; Humans; Injections, Intravenous; Isoproterenol; Male; Norepinephrine; Propranolol; Reproducibility of Results; Sodium Channel Blockers; Verapamil

1995

Other Studies

34 other study(ies) available for disopyramide and atropine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Ectopic atrial tachycardia on swallowing. Report on favourable effect of verapamil.
    Acta medica Scandinavica, 1979, Volume: 205, Issue:3

    Topics: Atrioventricular Node; Atropine; Cardiac Complexes, Premature; Deglutition; Disopyramide; Edrophonium; Electrocardiography; Female; Heart Atria; Heart Block; Hernia, Diaphragmatic; Hernia, Hiatal; Humans; Middle Aged; Practolol; Tachycardia; Verapamil

1979
Drugs used in the care of the cardiac patient.
    The Nursing clinics of North America, 1978, Volume: 13, Issue:3

    Topics: Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Atropine; Bretylium Tosylate; Cardiac Glycosides; Cardiovascular Diseases; Digitalis Glycosides; Disopyramide; Diuretics; Dose-Response Relationship, Drug; Humans; Isoproterenol; Lidocaine; Myocardial Contraction; Propranolol; Quinidine

1978
[Electrophysiological interrelations of disopyramide with atropine].
    Revista espanola de cardiologia, 1979, Volume: 32, Issue:2

    Topics: Arrhythmias, Cardiac; Atropine; Disopyramide; Drug Evaluation; Drug Interactions; Electrophysiology; Heart Conduction System; Humans; Pyridines

1979
Adverse hemodynamic effects of intravenous disopyramide compared with quinidine in conscious dogs.
    Circulation, 1979, Volume: 60, Issue:5

    Topics: Animals; Atropine; Autonomic Nervous System; Blood Pressure; Disopyramide; Dogs; Heart Rate; Hemodynamics; Injections, Intravenous; Propranolol; Pyridines; Quinidine; Stroke Volume

1979
Dual effect of disopyramide on atrial and atrioventricular conduction and refractory periods.
    British heart journal, 1977, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Atrioventricular Node; Atropine; Disopyramide; Female; Heart; Heart Atria; Heart Conduction System; Heart Ventricles; Humans; Male; Middle Aged; Neural Conduction; Parasympathetic Nervous System; Pyridines; Refractory Period, Electrophysiological

1977
[Effect of atropine, propafenon and disopyramide on "sino-atrial conduction time" in man].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1975, Volume: 81

    Topics: Anti-Arrhythmia Agents; Atropine; Disopyramide; Heart Rate; Humans; Propiophenones; Pyridines; Sinoatrial Node; Time Factors

1975
Comparison of anticholinergic effects of cibenzoline, disopyramide, and atropine.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:2

    Topics: Animals; Atropine; Brain; Cerebral Cortex; Disopyramide; Dogs; Electric Stimulation; Female; Heart; Heart Rate; Imidazoles; In Vitro Techniques; Infusions, Intravenous; Injections, Intravenous; Male; Membranes; Myocardium; Parasympatholytics; Rats; Rats, Inbred Strains; Vagus Nerve

1990
Anticholinergic action of disopyramide in intestinal smooth muscle of the guinea pig: inhibition of muscarinic receptors (M1 and M2).
    Japanese journal of pharmacology, 1990, Volume: 52, Issue:2

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Binding, Competitive; Carbachol; Cecum; Disopyramide; Guinea Pigs; Heart; Histamine; Ileum; In Vitro Techniques; Intestines; Male; Muscle, Smooth; Parasympatholytics; Quinuclidinyl Benzilate; Receptors, Muscarinic

1990
[Anti-arrhythmic activity of atropine, ritmilen, obsidan and cordarone in patients with ventricular allorhythmia].
    Klinicheskaia meditsina, 1989, Volume: 67, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Atropine; Cardiac Complexes, Premature; Disopyramide; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Propranolol

1989
Impairment of the antagonism of vecuronium-induced paralysis and intra-operative disopyramide administration.
    Anaesthesia, 1989, Volume: 44, Issue:1

    Topics: Atropine; Disopyramide; Drug Interactions; Humans; Intraoperative Care; Male; Middle Aged; Muscle Contraction; Neostigmine; Time Factors; Vecuronium Bromide

1989
[Differential therapeutic problems in sinus node syndrome--drug or electrical therapy?].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1986, Apr-01, Volume: 41, Issue:7

    Topics: Anti-Arrhythmia Agents; Atropine; Bundle of His; Cardiac Glycosides; Disopyramide; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Metaproterenol; Middle Aged; Pacemaker, Artificial; Prognosis; Sick Sinus Syndrome; Sinoatrial Node; Verapamil

1986
Antimuscarinic side-effects of disopyramide.
    Lancet (London, England), 1983, Apr-30, Volume: 1, Issue:8331

    Topics: Atropine; Biological Assay; Disopyramide; Humans; Parasympatholytics; Pyridines; Receptors, Muscarinic

1983
Cardiac transplantation--the ideal model for electrophysiologic drug testing?
    International journal of cardiology, 1983, Volume: 4, Issue:3

    Topics: Animals; Atropine; Cardiovascular Agents; Digoxin; Disopyramide; Edrophonium; Electrophysiology; Heart; Heart Conduction System; Heart Rate; Heart Transplantation; Humans; Norepinephrine; Quinidine

1983
The cellular electrophysiologic mechanism of the dual actions of disopyramide on rabbit sinus node function.
    Circulation, 1982, Volume: 66, Issue:6

    Topics: Action Potentials; Animals; Atrial Function; Atropine; Carbachol; Disopyramide; Dose-Response Relationship, Drug; Electrophysiology; Heart Atria; Pyridines; Rabbits; Sinoatrial Node

1982
Anticholinergic effects of disopyramide and quinidine on guinea pig myocardium. Mediation by direct muscarinic receptor blockade.
    Circulation research, 1980, Volume: 47, Issue:6

    Topics: Animals; Atropine; Disopyramide; Female; Guinea Pigs; Heart Atria; Male; Myocardium; Parasympatholytics; Physostigmine; Procainamide; Pyridines; Quinidine; Receptors, Muscarinic; Time Factors

1980
Development of a severe model of early coronary artery ligation-induced dysrhythmias in the anaesthetized rat.
    British journal of pharmacology, 1981, Volume: 73, Issue:4

    Topics: Androstanols; Angiotensin II; Animals; Arrhythmias, Cardiac; Atropine; Catecholamines; Coronary Vessels; Disease Models, Animal; Disopyramide; Epinephrine; Isoproterenol; Norepinephrine; Phenylephrine; Practolol; Rats; Ventricular Fibrillation

1981
Supernormal conduction and atrial echo beats in the dog.
    European heart journal, 1981, Volume: 2, Issue:6

    Topics: Action Potentials; Animals; Atrial Function; Atropine; Disopyramide; Dogs; Electric Stimulation; Heart Conduction System; Refractory Period, Electrophysiological; Sympathectomy, Chemical; Time Factors

1981
Electrophysiological effects of disopyramide and quinidine on guinea pig atria and canine cardiac purkinje fibers. Dependence on underlying cholinergic tone.
    Circulation research, 1980, Volume: 46, Issue:5

    Topics: Action Potentials; Animals; Atropine; Disopyramide; Dogs; Electrophysiology; Female; Guinea Pigs; Heart Atria; Heart Conduction System; Heart Rate; Male; Parasympatholytics; Physostigmine; Procainamide; Purkinje Fibers; Pyridines; Quinidine

1980
Electrophysiologic effects of disopyramide in children.
    Japanese heart journal, 1980, Volume: 21, Issue:4

    Topics: Adolescent; Arrhythmias, Cardiac; Atropine; Child; Child, Preschool; Disopyramide; Female; Heart Conduction System; Humans; Infant; Male; Parasympathetic Nervous System; Pyridines; Refractory Period, Electrophysiological

1980
Mechanisms of the atrium-specific positive inotropic activities of quinidine- and atropine-like agents in rats.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Bupivacaine; Catecholamines; Dimethylphenylpiperazinium Iodide; Disopyramide; Heart Atria; Isoproterenol; Male; Myocardial Contraction; Propranolol; Quinidine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Stimulation, Chemical

1997
Human atrial repolarization: effects of sinus rate, pacing and drugs on the surface electrocardiogram.
    Journal of the American College of Cardiology, 1999, Volume: 33, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atropine; Cardiac Pacing, Artificial; Disopyramide; Electrocardiography; Female; Flecainide; Heart Atria; Heart Block; Heart Rate; Humans; Injections, Intravenous; Male; Middle Aged; Propranolol; Reproducibility of Results

1999
Inhibition of isolated rat and human detrusor muscle contraction by disopyramide.
    Journal of autonomic pharmacology, 2000, Volume: 20, Issue:4

    Topics: Aged; Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Disopyramide; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Potassium; Rats; Rats, Wistar; Urinary Bladder

2000