Page last updated: 2024-09-04

disopyramide, (s)-isomer and amitriptyline

disopyramide, (s)-isomer has been researched along with amitriptyline in 1 studies

Compound Research Comparison

Studies (disopyramide, (s)-isomer)	Trials (disopyramide, (s)-isomer)	Recent Studies (post-2010) (disopyramide, (s)-isomer)	Studies (amitriptyline)	Trials (amitriptyline)	Recent Studies (post-2010) (amitriptyline)
5	0	0	6,935	1,381	1,060

Protein Interaction Comparison

Protein	Taxonomy	amitriptyline (IC50)
5-hydroxytryptamine receptor 4	Cavia porcellus (domestic guinea pig)	0.006
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	0.023
Muscarinic acetylcholine receptor M2	Homo sapiens (human)	0.081
Muscarinic acetylcholine receptor M4	Homo sapiens (human)	0.0053
Muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	0.3
Muscarinic acetylcholine receptor M3	Rattus norvegicus (Norway rat)	0.3
Muscarinic acetylcholine receptor M4	Rattus norvegicus (Norway rat)	0.3
5-hydroxytryptamine receptor 2C	Rattus norvegicus (Norway rat)	0.044
Muscarinic acetylcholine receptor M5	Rattus norvegicus (Norway rat)	0.3
Muscarinic acetylcholine receptor M5	Homo sapiens (human)	0.008
Alpha-2A adrenergic receptor	Homo sapiens (human)	0.1755
Muscarinic acetylcholine receptor M2	Rattus norvegicus (Norway rat)	0.3
Muscarinic acetylcholine receptor M1	Homo sapiens (human)	0.011
D(2) dopamine receptor	Homo sapiens (human)	1.009
5-hydroxytryptamine receptor 2A	Rattus norvegicus (Norway rat)	0.044
Alpha-2B adrenergic receptor	Homo sapiens (human)	0.004
Alpha-2C adrenergic receptor	Homo sapiens (human)	0.0295
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	1.02
Muscarinic acetylcholine receptor M3	Homo sapiens (human)	0.026
D(1A) dopamine receptor	Homo sapiens (human)	0.355
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	1.0324
Histamine H2 receptor	Homo sapiens (human)	0.73
Alpha-1D adrenergic receptor	Homo sapiens (human)	0.105
5-hydroxytryptamine receptor 2A	Homo sapiens (human)	0.015
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	0.006
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	1.02
5-hydroxytryptamine receptor 1D	Rattus norvegicus (Norway rat)	0.044
5-hydroxytryptamine receptor 1F	Rattus norvegicus (Norway rat)	0.044
5-hydroxytryptamine receptor 2B	Rattus norvegicus (Norway rat)	0.044
5-hydroxytryptamine receptor 6	Rattus norvegicus (Norway rat)	0.044
Sodium-dependent serotonin transporter	Homo sapiens (human)	0.2756
5-hydroxytryptamine receptor 7	Rattus norvegicus (Norway rat)	0.044
5-hydroxytryptamine receptor 5A	Rattus norvegicus (Norway rat)	0.044
5-hydroxytryptamine receptor 5B	Rattus norvegicus (Norway rat)	0.044
Histamine H1 receptor	Homo sapiens (human)	0.0048
D(3) dopamine receptor	Homo sapiens (human)	0.182
5-hydroxytryptamine receptor 3A	Rattus norvegicus (Norway rat)	0.044
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	0.07
Histamine H2 receptor	Cavia porcellus (domestic guinea pig)	0.66
5-hydroxytryptamine receptor 6	Homo sapiens (human)	0.14
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	7.2446
Sodium channel protein type 5 subunit alpha	Homo sapiens (human)	1.6
Sodium channel protein type 9 subunit alpha	Homo sapiens (human)	4
5-hydroxytryptamine receptor 4	Rattus norvegicus (Norway rat)	0.044
Sodium channel protein type 2 subunit alpha	Homo sapiens (human)	3.1
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	1.031
5-hydroxytryptamine receptor 3B	Rattus norvegicus (Norway rat)	0.044

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1

Other Studies

1 other study(ies) available for disopyramide, (s)-isomer and amitriptyline

Article	Year
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008

Article

Year

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008