disodium cantharidin has been researched along with cantharidin in 7 studies
*Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally. [MeSH]
*Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally. [MeSH]
Studies (disodium cantharidin) | Trials (disodium cantharidin) | Recent Studies (post-2010) (disodium cantharidin) | Studies (cantharidin) | Trials (cantharidin) | Recent Studies (post-2010) (cantharidin) |
---|---|---|---|---|---|
7 | 1 | 5 | 875 | 27 | 307 |
Protein | Taxonomy | disodium cantharidin (IC50) | cantharidin (IC50) |
---|---|---|---|
Protein phosphatase 1B | Homo sapiens (human) | 1.78 | |
Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | 3.6 | |
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | Homo sapiens (human) | 1.78 | |
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B | Gallus gallus (chicken) | 0.63 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (28.57) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (57.14) | 24.3611 |
2020's | 1 (14.29) | 2.80 |
Authors | Studies |
---|---|
Chen, X; Zhang, YH | 1 |
Fu, NW; Quan, LP; Zhang, LS | 1 |
Hong, G; Luo, X; Shao, H | 1 |
Cui, J; Wang, B | 1 |
Song, J; Wang, LZ; Zhang, HJ | 1 |
Chen, L; Chen, Y; Ding, J; Feng, J; Gong, Q; Hu, S; Li, X; Liu, H; Liu, S; Tan, Z; Tang, F; Wang, C; Xiao, Z; Zhou, M | 1 |
Li, J; Liu, X; Zhou, C; Zhu, M | 1 |
1 review(s) available for disodium cantharidin and cantharidin
Article | Year |
---|---|
Clinical efficacy and safety of sodium cantharidinate plus chemotherapy in non-small-cell lung cancer: A systematic review and meta-analysis of 38 randomized controlled trials.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cantharidin; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Quality of Life; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome | 2019 |
1 trial(s) available for disodium cantharidin and cantharidin
Article | Year |
---|---|
Treatment of mid-late stage NSCLC using sodium cantharidinate/vitamin B6/GP regimen in clinic.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cantharidin; Carcinoma, Non-Small-Cell Lung; China; Drug-Related Side Effects and Adverse Reactions; Humans; Neoplasm Staging; Quality of Life; Treatment Outcome; Vitamin B 6 | 2014 |
5 other study(ies) available for disodium cantharidin and cantharidin
Article | Year |
---|---|
[Effect of disodium cantharidate and injectable herbal medicine on energy and cyclic nucleotide metabolism in hepatoma 22 cells and liver tissues of tumor-bearing mice].
Topics: Animals; Antineoplastic Agents; Cantharidin; Cyclic AMP; Cyclic GMP; Energy Metabolism; Liver Neoplasms, Experimental; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Mice; Plant Extracts; Plants, Medicinal | 1985 |
[The antitumor effect and a pharmacological study of disodium cantharidate (author's transl)].
Topics: Animals; Antineoplastic Agents; Blood Cells; Bone Marrow; Cantharidin; Liver Neoplasms, Experimental; Mice | 1980 |
Evaluation of sodium cantharidinate/vitamin B6 in the treatment of primary liver cancer.
Topics: Adult; Cantharidin; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Treatment Outcome; Vitamin B 6 | 2014 |
Efficacy of mannatide combined with sodium cantharidate vitamin B6 in the treatment of malignant pleural effusions.
Topics: Adult; Aged; Antineoplastic Agents; Cantharidin; Case-Control Studies; Cisplatin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Mannose; Middle Aged; Neoplasm Staging; Neoplasms; Pleural Effusion, Malignant; Prognosis; Vitamin B 6; Vitamin B Complex | 2015 |
Effect of sodium cantharidinate/vitamin B6 injection on survival, liver function, immune function, and quality of life in patients with hepatocellular carcinoma: Protocol for a meta-analysis.
Topics: Cantharidin; Carcinoma, Hepatocellular; China; Drug Therapy, Combination; Humans; Immune System; Injections; Liver; Liver Neoplasms; Medicine, Chinese Traditional; Meta-Analysis as Topic; Prospective Studies; Quality of Life; Randomized Controlled Trials as Topic; Safety; Survival; Systematic Review as Topic; Treatment Outcome; Vitamin B 6; Vitamin B Complex | 2020 |