Page last updated: 2024-09-03

disodium cantharidin and cantharidin

disodium cantharidin has been researched along with cantharidin in 7 studies

*Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally. [MeSH]

*Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally. [MeSH]

Compound Research Comparison

Studies
(disodium cantharidin)
Trials
(disodium cantharidin)
Recent Studies (post-2010)
(disodium cantharidin)
Studies
(cantharidin)
Trials
(cantharidin)
Recent Studies (post-2010) (cantharidin)
71587527307

Protein Interaction Comparison

ProteinTaxonomydisodium cantharidin (IC50)cantharidin (IC50)
Protein phosphatase 1BHomo sapiens (human)1.78
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)3.6
Serine/threonine-protein phosphatase PP1-gamma catalytic subunitHomo sapiens (human)1.78
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B Gallus gallus (chicken)0.63

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Chen, X; Zhang, YH1
Fu, NW; Quan, LP; Zhang, LS1
Hong, G; Luo, X; Shao, H1
Cui, J; Wang, B1
Song, J; Wang, LZ; Zhang, HJ1
Chen, L; Chen, Y; Ding, J; Feng, J; Gong, Q; Hu, S; Li, X; Liu, H; Liu, S; Tan, Z; Tang, F; Wang, C; Xiao, Z; Zhou, M1
Li, J; Liu, X; Zhou, C; Zhu, M1

Reviews

1 review(s) available for disodium cantharidin and cantharidin

ArticleYear
Clinical efficacy and safety of sodium cantharidinate plus chemotherapy in non-small-cell lung cancer: A systematic review and meta-analysis of 38 randomized controlled trials.
    Journal of clinical pharmacy and therapeutics, 2019, Volume: 44, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cantharidin; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Quality of Life; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome

2019

Trials

1 trial(s) available for disodium cantharidin and cantharidin

ArticleYear
Treatment of mid-late stage NSCLC using sodium cantharidinate/vitamin B6/GP regimen in clinic.
    Journal of cancer research and therapeutics, 2014, Volume: 10 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cantharidin; Carcinoma, Non-Small-Cell Lung; China; Drug-Related Side Effects and Adverse Reactions; Humans; Neoplasm Staging; Quality of Life; Treatment Outcome; Vitamin B 6

2014

Other Studies

5 other study(ies) available for disodium cantharidin and cantharidin

ArticleYear
[Effect of disodium cantharidate and injectable herbal medicine on energy and cyclic nucleotide metabolism in hepatoma 22 cells and liver tissues of tumor-bearing mice].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1985, Volume: 5, Issue:11

    Topics: Animals; Antineoplastic Agents; Cantharidin; Cyclic AMP; Cyclic GMP; Energy Metabolism; Liver Neoplasms, Experimental; Male; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Mice; Plant Extracts; Plants, Medicinal

1985
[The antitumor effect and a pharmacological study of disodium cantharidate (author's transl)].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1980, Volume: 2, Issue:2

    Topics: Animals; Antineoplastic Agents; Blood Cells; Bone Marrow; Cantharidin; Liver Neoplasms, Experimental; Mice

1980
Evaluation of sodium cantharidinate/vitamin B6 in the treatment of primary liver cancer.
    Journal of cancer research and therapeutics, 2014, Volume: 10 Suppl 1

    Topics: Adult; Cantharidin; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Humans; Liver Neoplasms; Male; Middle Aged; Treatment Outcome; Vitamin B 6

2014
Efficacy of mannatide combined with sodium cantharidate vitamin B6 in the treatment of malignant pleural effusions.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Cantharidin; Case-Control Studies; Cisplatin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Mannose; Middle Aged; Neoplasm Staging; Neoplasms; Pleural Effusion, Malignant; Prognosis; Vitamin B 6; Vitamin B Complex

2015
Effect of sodium cantharidinate/vitamin B6 injection on survival, liver function, immune function, and quality of life in patients with hepatocellular carcinoma: Protocol for a meta-analysis.
    Medicine, 2020, Aug-21, Volume: 99, Issue:34

    Topics: Cantharidin; Carcinoma, Hepatocellular; China; Drug Therapy, Combination; Humans; Immune System; Injections; Liver; Liver Neoplasms; Medicine, Chinese Traditional; Meta-Analysis as Topic; Prospective Studies; Quality of Life; Randomized Controlled Trials as Topic; Safety; Survival; Systematic Review as Topic; Treatment Outcome; Vitamin B 6; Vitamin B Complex

2020