dipyrone has been researched along with morphine in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (8.00) | 18.7374 |
| 1990's | 14 (18.67) | 18.2507 |
| 2000's | 33 (44.00) | 29.6817 |
| 2010's | 19 (25.33) | 24.3611 |
| 2020's | 3 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brasseur, L; Charpak, Y; Larue, F | 1 |
| Drenska, D | 1 |
| Gastmeier, K; Hass, M; Kuteifan, K; Schott, H | 1 |
| Richter, R; Sittl, R | 1 |
| Bantoutova, I; Sourcheva, S; Vlaskovska, M | 1 |
| Carlsson, KH; Jurna, I; Monzel, W | 1 |
| Carlsson, KH; Jurna, I | 1 |
| Coelho, JC; Herfarth, C; Messmer, K; Runkel, N; Senninger, N | 1 |
| Carlsson, KH; Helmreich, J; Jurna, I | 1 |
| Ivanov, K; Nikolov, R | 1 |
| Heino, A; Rosenberg, PH; Scheinin, B | 1 |
| Abdu-Aguye, I; Abdurahman, EM; Hussaini, IM; Johnson, PB; Okolo, CO | 1 |
| Hofstetter, B; Jokisch, D; Lange, V; Misera, A; Schulte-Steinberg, H; Stein, C; Weninger, E | 1 |
| Lopez-Muñoz, FJ; Salazar, LA; Terron, JA; Villalon, CM | 1 |
| Aliaga, L; Barutell, C; Gálvez, R; Moreno, J; Ortiz, P; Pallarés, J; Puerta, J; Rodríguez, M; Rull, M; Vidal, F | 1 |
| Bischof, C; Börstinghaus, D; Georgieff, M; Rockemann, MG; Seeling, W; Steffen, P | 1 |
| Reeker, W; Tempel, G; von Hundelshausen, B | 1 |
| Coudert, P; Couquelet, J; Rohet, F; Rubat, C | 1 |
| Fernaud, I; Mellström, B; Naranjo, JR; Taylor, J | 1 |
| Aguirre-Bañuelos, P; Granados-Soto, V | 2 |
| Alpert, I; Itskovitz-Eldor, J; Jakobi, P; Solt, I; Weiner, Z; Zimmer, EZ | 1 |
| Tortorici, V; Vanegas, H | 1 |
| Abbott, FV; Saddi, GM | 1 |
| Czarnecka, E; Pakulska, W | 2 |
| Pontes, RM; Prado, WA | 1 |
| Díaz Reval, MI; Domínguez Ramírez, AM; Hernández-Delgadillo, GP; López-Muñoz, FJ; Ventura Martínez, R | 1 |
| Berlese, DB; Mello, CF; Rubin, MA; Sauzem, PD; Tabarelli, Z | 1 |
| Cunha, FQ; Ferreira, SH; Parada, CA; Tambeli, CH; Vivancos, GG | 1 |
| Cordón, C; Hernando, F; Moreno, A; Perez, E; Portolés, A; Terleira, A; Vargas, E | 1 |
| Diéguez Fernández, M; Fernández Goti, C; Figueira Moure, A; Pensado Castiñeiras, A; Portela Torrón, F; Ramil Fraga, C; Sánchez Galindo, A; Sanduende Otero, Y; Vázquez Fidalgo, A; Zavanella Botta, C | 1 |
| Cruz, SL; Hernández-Delgadillo, GP; López-Muñoz, FJ; Salazar, LA | 1 |
| Cruz, SL; Hernández-Delgadillo, GP | 2 |
| Coelho, LP; Coelho, MG; da Costa e Silva, MC; da Silva Lopes, C; de Carvalho Sabino, KC; de Castro, FL; Gayer, CR; Reis, PA; Todeschini, AR | 1 |
| Bertollo, CM; Coelho, MM; Costa, KA; Glória, MB; Moraes-Santos, T; Nascimento, EB; Oliveira, AC; Rocha, LT; Souza, AL | 1 |
| Curatolo, M; Eichenberger, U; Sveticic, G | 1 |
| Ivanova, T; Kasakov, L; Pavlova, E; Philipova, T; Vlaskovska, M | 1 |
| Déciga-Campos, M; Guerrero-Analco, JA; Mata, R; Quijano, L | 1 |
| Caba Barrientos, F; Echevarría Moreno, M; Hernández García, D; Lara Vila, I; Núñez García, A; Ramos Curado, P | 1 |
| Martínez, E; Rodríguez Huertas, E; Rodríguez, R; Santana, M | 1 |
| Del Giglio, A; Duarte Souza, JF; Lajolo, PP; Pinczowski, H | 1 |
| de Madaria, E; Horga, JF; Llorens, P; Martínez, E; Martínez, J; Peiró, AM; Pérez-Mateo, M | 1 |
| Gehling, M; Tryba, M | 1 |
| Gurtskaia, G; Tsagareli, M; Tsiklauri, N | 1 |
| Cortés-Arroyo, AR; Domínguez-Ramírez, AM; Godínez-Chaparro, B; Guevara-López, U; Huerta-Cruz, JC; López-Muñoz, FJ | 1 |
| Bonjardim, LR; da Silva, AP; Ferraz de Arruda Veiga, MC; Gameiro, GH; Tambeli, CH | 1 |
| Beck, P; Bonacorso, HG; Drewes, C; Ferreira, J; Machado, P; Martins, MA; Mello, CF; Milano, J; Oliveira, SM; Rossato, MF; Rubin, MA; Zanatta, N | 1 |
| Acevedo, H; Aponte, Y; Nogueira, L; Tortorici, V; Vanegas, H | 1 |
| Gehling, MH; Kulka, PJ; Luesebrink, T; Tryba, M | 1 |
| Bein, B; Francksen, H; Hanss, R; Mayer, L; Ohnesorge, H; Scholz, J; Tonner, PH | 1 |
| Bahar, M; Cakmakkaya, OS; Korkmaz Dilmen, O; Tunali, Y; Tureci, E; Tutuncu, AC; Yentur, E | 1 |
| Cortés-Arroyo, AR; Domínguez-Ramírez, AM; López, JR; López-Muñoz, FJ; Y de la Peña, MH | 1 |
| Arslan, R; Bektas, N | 1 |
| Barth, J; Eichhorn, A | 1 |
| Abzianidze, E; Gurtskaia, G; Nozadze, I; Tsagareli, MG; Tsiklauri, N | 1 |
| Alvarez, HD; Chaparro, LE; Joaqui, W; Lezcano, W | 1 |
| Chuchracki, M; Gaca, M; Michalska, M; Mojs, E; Samulak, D; Wilczak, M | 1 |
| Beckmann, MW; Dittrich, R; Geisler, K; Hoffmann, I; Künzel, J; Müller, A | 1 |
| Alexandre-Moreira, MS; Alves, MA; Barreiro, EJ; Beraldo, H; Castellano, EE; Júnior, WB; Lima, LM; Parrilha, GL; Perez-Rebolledo, A; Piro, OE | 1 |
| Knapik, P; Korlacki, W; Misiolek, H; Walaszczyk, M | 1 |
| Calzadilla, PC; Cortés-Arroyo, AR; Domínguez-Ramírez, AM; Gómez-Hernández, M; Hurtado Y de la Peña, M; López, JR; López-Muñoz, FJ | 1 |
| Alexandre-Moreira, MS; Barbosa Brito da Matta, C; Barbosa-Filho, JM; Cavalcante-Silva, LHA; De Araújo, MV; De Miranda, GEC; De Oliveira Santos, BV; Pereira de Lira, D | 1 |
| Barthó, L; Benkó, R; Bölcskei, K; Boros, M; Pethő, G; Szolcsányi, J | 1 |
| Bicanic, G; Delimar, D; Hrabac, P; Oreskovic, Z; Tripkovic, B | 1 |
| Konopka-Filippow, M; Sierko, E; Skalij, P; Wójtowicz, A; Wojtukiewicz, MZ; Zabrocka, E | 1 |
| Beck, V; Duarte, MM; Duarte, T; Godoy, JP; Godoy, MC; Menezes, MS; Ortiz, MP; Ortiz, RP; Rigo, FK; Santiago, ES; Schlosser, RS | 1 |
| Carrillo-Calzadilla, PE; Cortés-Arroyo, AR; Domínguez-Ramírez, AM; López-Muñoz, FJ; Medina-López, JR; Moreno-Rocha, LA | 1 |
| Castilla Parrilla, EM; Castilla Peinado, G; García Dueñas, C; Gironés Camarasa, B; Liceras Liceras, E; Mattar Sattuf, K | 1 |
| Balk, M; Gostian, AO; Gostian, M; Heindl, LM; Loeser, J; Otte, M; Schwarz, D; Tholen, C; Wolber, P | 1 |
| Bonn, GK; Fiegl-Lechner, A; Harder, M; Horvath, UEI; Jeske, M; Kerndler, S; Oberacher, H; Rainer, M; Schlager, A; Schüllner, F | 1 |
| Dorau, W; Eppler, F; Häske, D; Heinemann, N; Schempf, B; Schopp, T | 1 |
18 trial(s) available for dipyrone and morphine
| Article | Year |
|---|---|
Comparison of intramuscular analgesia, intercostal block, epidural morphine and on-demand-i.v.-fentanyl in the control of pain after upper abdominal surgery.
Topics: Abdomen; Adult; Analgesia; Benzilates; Benzophenones; Bupivacaine; Dipyrone; Drug Combinations; Epidural Space; Female; Fentanyl; Humans; Infusions, Parenteral; Injections; Injections, Intramuscular; Intercostal Muscles; Male; Middle Aged; Morphine; Nerve Block; Oxycodone; Pain, Postoperative; Respiration | 1984 |
Intraperitoneal versus interpleural morphine or bupivacaine for pain after laparoscopic cholecystectomy.
Topics: Bupivacaine; Cholecystectomy; Dipyrone; Double-Blind Method; Humans; Injections, Intraperitoneal; Laparoscopy; Morphine; Pain Management; Pleura; Tramadol | 1995 |
Efficacy and tolerance of oral dipyrone versus oral morphine for cancer pain.
Topics: Adult; Aged; Dipyrone; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Pain; Pain Measurement | 1994 |
Prophylactic use of epidural mepivacaine/morphine, systemic diclofenac, and metamizole reduces postoperative morphine consumption after major abdominal surgery.
Topics: Abdomen; Adult; Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dipyrone; Female; Humans; Kidney; Male; Mepivacaine; Middle Aged; Morphine; Pain, Postoperative; Respiration | 1996 |
The opiate-sparing effect of dipyrone in post-operative pain therapy with morphine using a patient-controlled analgesic system.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Blood Coagulation; Dipyrone; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Respiration; Single-Blind Method | 1996 |
[Cost-effectiveness analysis of patient-controlled analgesia compared to continuous elastomeric pump infusion of tramadol and metamizole].
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Cost-Benefit Analysis; Dipyrone; Drug Costs; Elastomers; Equipment Design; Female; Gynecologic Surgical Procedures; Hospital Costs; Humans; Infusion Pumps; Infusions, Intravenous; Laparotomy; Middle Aged; Morphine; Nausea; Ondansetron; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Tramadol; Vomiting | 2007 |
[Stress response under continuous infusion of remifentanil compared to bolus doses of fentanyl assessed by levels of cytokines, C-reactive protein, and cortisol during and after abdominal hysterectomy].
Topics: Aged; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; C-Reactive Protein; Dipyrone; Double-Blind Method; Drug Administration Schedule; Female; Fentanyl; Humans; Hydrocortisone; Hysterectomy; Inflammation; Infusions, Intravenous; Injections, Intravenous; Interleukin-10; Interleukin-6; Intraoperative Complications; Kinetics; Middle Aged; Morphine; Narcotics; Pain, Postoperative; Piperidines; Postoperative Complications; Remifentanil; Stress, Physiological | 2007 |
Adjunct dipyrone in association with oral morphine for cancer-related pain: the sooner the better.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Brazil; Dipyrone; Double-Blind Method; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Pain; Placebos | 2007 |
Efficacy and tolerance of metamizole versus morphine for acute pancreatitis pain.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Female; Humans; Male; Middle Aged; Morphine; Pain; Pancreatitis; Pilot Projects | 2008 |
[Intrathecal morphine in orthopaedic surgery patients. Optimised dose in patients receiving dipyrone].
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Dipyrone; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Spinal; Male; Middle Aged; Morphine; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Prospective Studies | 2008 |
The effective duration of analgesia after intrathecal morphine in patients without additional opioid analgesia: a randomized double-blind multicentre study on orthopaedic patients.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double-Blind Method; Female; Hemodynamics; Humans; Injections, Spinal; Kaplan-Meier Estimate; Male; Middle Aged; Morphine; Orthopedic Procedures; Oxygen; Pain Measurement; Pain, Postoperative; Pruritus; Respiratory Mechanics; Sample Size; Time Factors | 2009 |
Paracetamol versus metamizol in the treatment of postoperative pain after breast surgery: a randomized, controlled trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Breast; Dipyrone; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Middle Aged; Morphine; Pain, Postoperative; Postoperative Nausea and Vomiting; Treatment Outcome | 2009 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double-Blind Method; Female; Humans; Lumbar Vertebrae; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Piroxicam; Prospective Studies; Treatment Outcome | 2010 |
Analgesic effectiveness of dipyrone (metamizol) for postoperative pain after herniorrhaphy: a randomized, double-blind, dose-response study.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Dipyrone; Double-Blind Method; Female; Herniorrhaphy; Humans; Male; Middle Aged; Morphine; Pain, Postoperative; Young Adult | 2012 |
Efficiency of postoperative pain management after gynecologic oncological surgeries with the use of morphine + acetaminophen + ketoprofen versus morphine + metamizol + ketoprofen.
Topics: Acetaminophen; Analgesics; Carcinoma; Dipyrone; Drug Therapy, Combination; Endometrial Neoplasms; Female; Gynecologic Surgical Procedures; Humans; Ketoprofen; Morphine; Ovarian Neoplasms; Pain Measurement; Pain, Postoperative; Treatment Outcome; Uterine Cervical Neoplasms | 2011 |
Treatment of postoperative pain after total hip arthroplasty: comparison between metamizol and paracetamol as adjunctive to opioid analgesics-prospective, double-blind, randomised study.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arthroplasty, Replacement, Hip; Dipyrone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies | 2014 |
Effect of endovenous lidocaine on analgesia and serum cytokines: double-blinded and randomized trial.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; Cytokines; Dipyrone; Double-Blind Method; Female; Humans; Ileus; Infusions, Intravenous; Length of Stay; Lidocaine; Male; Middle Aged; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Perioperative Care; Prospective Studies | 2016 |
[Comparative study of the effect of two analgesic techniques in postoperative pain control in pediatric surgery].
Topics: Abdomen; Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Dipyrone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Time Factors; Tramadol | 2018 |
57 other study(ies) available for dipyrone and morphine
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[Postoperative analgesia in France. A study of the prescribing doctor's approach].
Topics: Acetaminophen; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Drug Prescriptions; Drug Therapy, Combination; Female; France; Humans; Male; Middle Aged; Morphine; Morphine Derivatives; Pain, Postoperative; Postoperative Care; Postoperative Period; Surveys and Questionnaires | 1992 |
[Anthocyanins and analgesics or a possibility of a new analgetic combination].
Topics: Analgesics; Animals; Anthocyanins; Dipyrone; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Male; Mice; Morphine; Pain | 1991 |
[Pain therapy for urologic cancer patients at the Potsdam district hospital--initial results].
Topics: Aged; Amitriptyline; Analgesics; Analgesics, Opioid; Aspirin; Carbamazepine; Codeine; Dipyrone; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Indomethacin; Meperidine; Morphine; Pain; Pain Measurement; Prospective Studies; Urologic Neoplasms | 1990 |
[Cancer pain therapy in children and adolescents using morphine].
Topics: Adolescent; Child; Child, Preschool; Dipyrone; Drug Therapy, Combination; Humans; Infant; Morphine; Neoplasms; Pain | 1991 |
Participation of the POMC-system in the effects of morphine on the avoidance reaction in albino rats.
Topics: Adrenalectomy; Animals; Aspirin; Avoidance Learning; Dexamethasone; Dipyrone; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Pro-Opiomelanocortin; Rats; Rats, Inbred Strains; Stress, Psychological | 1990 |
Depression by morphine and the non-opioid analgesic agents, metamizol (dipyrone), lysine acetylsalicylate, and paracetamol, of activity in rat thalamus neurones evoked by electrical stimulation of nociceptive afferents.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Dipyrone; Electric Stimulation; Female; Lysine; Male; Morphine; Neurons; Nociceptors; Rats; Rats, Inbred Strains; Thalamus | 1988 |
The role of descending inhibition in the antinociceptive effects of the pyrazolone derivatives, metamizol (dipyrone) and aminophenazone ("Pyramidon").
Topics: Aminopyrine; Analgesics; Animals; Axons; Dipyrone; Female; Male; Microinjections; Morphine; Periaqueductal Gray; Procaine; Rats; Rats, Inbred Strains; Reaction Time; Substantia Nigra | 1987 |
Effect of analgesic drugs on the electromyographic activity of the gastrointestinal tract and sphincter of Oddi and on biliary pressure.
Topics: Ampulla of Vater; Analgesics; Animals; Aspirin; Biliary Tract; Dipyrone; Electromyography; Female; Gastrointestinal Motility; Hydrostatic Pressure; Male; Meperidine; Morphine; Opossums; Pentazocine; Sphincter of Oddi; Tramadol | 1986 |
Activation of inhibition from the periaqueductal grey matter mediates central analgesic effect of metamizol (dipyrone).
Topics: Action Potentials; Aminopyrine; Animals; Dipyrone; Female; Male; Morphine; Naloxone; Nerve Fibers; Neural Inhibition; Pain; Pain Measurement; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substantia Nigra | 1986 |
[The feasibility of assessing analgesia using the Randell-Selitto method].
Topics: Analgesics; Animals; Dipyrone; Female; Morphine; Pentazocine; Rats | 1974 |
Analgesic effect of Irvingia gabonensis stem bark extract.
Topics: Analgesics; Animals; Dipyrone; Dose-Response Relationship, Drug; Ethanol; Hot Temperature; Male; Mice; Morphine; Nigeria; Pain; Pain Measurement; Plant Extracts; Plant Stems; Water | 1995 |
Analgesic interactions produced by combinations of dipyrone and morphine in the rat.
Topics: Analgesics; Animals; Dipyrone; Female; Hindlimb; Morphine; Pain; Pain Measurement; Rats; Rats, Wistar; Uric Acid | 1994 |
Synthesis and analgesic effects of 3-substituted 4,6-diarylpyridazine derivatives of the arylpiperazine class.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoquinones; Dipyrone; Dose-Response Relationship, Drug; Drug Design; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Neurotoxins; Pain; Pyrazolones; Pyridazines; Receptors, Opioid; Reference Standards; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Trazodone | 1997 |
Metamizol potentiates morphine effects on visceral pain and evoked c-Fos immunoreactivity in spinal cord.
Topics: Acetic Acid; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Drug Synergism; Immunohistochemistry; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Morphine; Naloxone; Narcotic Antagonists; Pain; Proto-Oncogene Proteins c-fos; Spinal Cord; Visceral Afferents | 1998 |
Evidence for a peripheral mechanism of action for the potentiation of the antinociceptive effect of morphine by dipyrone.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclic GMP; Dipyrone; Drug Synergism; Female; Morphine; Naloxone; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar | 1999 |
Oral analgesia in the treatment of post-cesarean pain.
Topics: Adult; Analgesia; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Dipyrone; Female; Humans; Morphine; Pain, Postoperative; Patient Satisfaction; Pregnancy; Prospective Studies | 2000 |
Peripheral antinociceptive interaction of dipyrone and morphine in the formalin test.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Formaldehyde; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Measurement; Peripheral Nervous System; Rats; Rats, Wistar | 2000 |
Opioid tolerance induced by metamizol (dipyrone) microinjections into the periaqueductal grey of rats.
Topics: Animals; Dipyrone; Drug Tolerance; Hot Temperature; Male; Mesencephalon; Microinjections; Morphine; Naloxone; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Time Factors; Wakefulness | 2000 |
The formalin test in the mouse: a parametric analysis of scoring properties.
Topics: Acepromazine; Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Amphetamine; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Dipyrone; Dose-Response Relationship, Drug; Habituation, Psychophysiologic; Indomethacin; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Pain Measurement; Pentobarbital; Pimozide; Sensitivity and Specificity; Xylazine | 2000 |
Effect of diazepam and midazolam on the antinociceptive effect of morphine, metamizol and indomethacin in mice.
Topics: Analgesics; Animals; Anti-Anxiety Agents; Diazepam; Dipyrone; Dose-Response Relationship, Drug; Drug Interactions; Indomethacin; Male; Mice; Midazolam; Morphine; Pain Measurement; Reaction Time | 2001 |
Presurgical ketoprofen, but not morphine, dipyrone, diclofenac or tenoxicam, preempts post-incisional mechanical allodynia in rats.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dipyrone; Ketoprofen; Male; Mechanoreceptors; Morphine; Pain Threshold; Pain, Postoperative; Physical Stimulation; Piroxicam; Postoperative Care; Preoperative Care; Rats; Rats, Wistar | 2002 |
Metamizol potentiates morphine antinociception but not constipation after chronic treatment.
Topics: Analgesics; Animals; Constipation; Dipyrone; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Male; Morphine; Naloxone; Pain Measurement; Rats; Rats, Wistar | 2002 |
Influence of mianserin on the antinociceptive effect of morphine, metamizol and indomethacin in mice.
Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Dipyrone; Drug Synergism; Drug Therapy, Combination; Indomethacin; Injections, Intraperitoneal; Male; Mianserin; Mice; Models, Animal; Morphine; Pain; Pain Measurement | 2002 |
Antinociceptive effects of Cremophor EL orally administered to mice.
Topics: Administration, Oral; Analgesics; Animals; Castor Oil; Dipyrone; Glycerol; Male; Mice; Morphine; Pain Measurement | 2003 |
Activation of presynaptic NMDA receptors coupled to NaV1.8-resistant sodium channel C-fibers causes retrograde mechanical nociceptor sensitization.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dose-Response Relationship, Drug; Ganglia, Spinal; Glutamates; Inflammation; Morphine; NAV1.8 Voltage-Gated Sodium Channel; Neuropeptides; Nociceptors; Oligonucleotides, Antisense; Pain Measurement; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Channels; Spinal Cord; Time Factors | 2003 |
Effect of adverse drug reactions on length of stay in surgical intensive care units.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; APACHE; Dipyrone; Drug-Related Side Effects and Adverse Reactions; Female; Hospital Costs; Hospitals, Urban; Humans; Intensive Care Units; Length of Stay; Male; Meperidine; Middle Aged; Morphine; Multivariate Analysis; Postoperative Care; Prospective Studies; Regression Analysis; Severity of Illness Index; Spain; Surgical Procedures, Operative | 2003 |
[Early extubation with caudal morphine after pediatric heart surgery].
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Caudal; Anesthesia, General; Child; Child, Preschool; Critical Care; Dipyrone; Extracorporeal Membrane Oxygenation; Female; Heart Defects, Congenital; Humans; Infant; Intensive Care Units, Pediatric; Intubation, Intratracheal; Length of Stay; Male; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies | 2003 |
Morphine and dipyrone co-administration delays tolerance development and potentiates antinociception.
Topics: Analgesics; Animals; Dipyrone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Male; Morphine; Pain Measurement; Rats; Rats, Wistar | 2003 |
Dipyrone potentiates morphine-induced antinociception in dipyrone-treated and morphine-tolerant rats.
Topics: Analgesics; Animals; Dipyrone; Drug Synergism; Drug Tolerance; Male; Morphine; Pain Measurement; Rats; Rats, Wistar | 2004 |
Antinociceptive properties of ethanolic extract and fractions of Pterodon pubescens Benth. seeds.
Topics: Abdomen; Administration, Oral; Analgesics; Animals; Aspirin; Chemical Fractionation; Dipyrone; Diterpenes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethanol; Fabaceae; Formaldehyde; Gas Chromatography-Mass Spectrometry; Inflammation; Male; Mice; Morphine; Pain Measurement; Plant Extracts; Plant Oils; Seeds; Sesquiterpenes; Tail; Temperature | 2005 |
Pharmacological investigation of the nociceptive response and edema induced by venom of the scorpion Tityus serrulatus.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cyproheptadine; Dipyrone; Edema; Indomethacin; Injections, Subcutaneous; Male; Mice; Morphine; Pain; Pain Threshold; Promethazine; Rats; Rats, Wistar; Scorpion Venoms; Scorpions; Serotonin | 2005 |
Safety of mixture of morphine with ketamine for postoperative patient-controlled analgesia: an audit with 1026 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Dissociative; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Drug Combinations; Female; Humans; Ketamine; Ketorolac; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Treatment Outcome | 2005 |
Nandrolone modulates the non-opioid and opioid analgesia and tolerance/dependence: role of sexual dimorphism.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Central Nervous System; Dipyrone; Drug Tolerance; Female; Male; Morphine; Nandrolone; Rats; Rats, Wistar; Sexual Behavior, Animal; Substance Withdrawal Syndrome; Substance-Related Disorders | 2003 |
Antinociceptive activity of 3-O-beta-d-glucopyranosyl-23,24-dihydrocucurbitacin F from Hintonia standleyana (Rubiaceae).
Topics: Analgesics; Dipyrone; Glyburide; Morphine; NG-Nitroarginine Methyl Ester; Rubiaceae; Saponins; Spectrum Analysis | 2006 |
Endogenous opioids are involved in morphine and dipyrone analgesic potentiation in the tail flick test in rats.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dose-Response Relationship, Drug; Drug Synergism; Male; Morphine; Naloxone; Narcotic Antagonists; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Time Factors | 2006 |
Study of non-opioid analgesics tolerance in young and adult rats.
Topics: Age Factors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyrone; Drug Tolerance; Ketorolac; Lysine; Morphine; Nociceptors; Piroxicam; Rats; Time Factors | 2008 |
The antinociceptive efficacy of morphine, metamizol, or their combination in an experimental rat model with different levels of inflammatory pain.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dipyrone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Inflammation; Male; Morphine; Pain; Pain Measurement; Rats; Rats, Wistar; Uric Acid | 2008 |
Nociceptive behavior induced by mustard oil injection into the temporomandibular joint is blocked by a peripheral non-opioid analgesic and a central opioid analgesic.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Dipyrone; Dose-Response Relationship, Drug; Lidocaine; Morphine; Mustard Plant; Pain; Plant Oils; Rats; Temporomandibular Joint; Tramadol | 2009 |
Antinociceptive action of 4-methyl-5-trifluoromethyl-5-hydroxy-4, 5-dihydro-1H-pyrazole methyl ester in models of inflammatory pain in mice.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dipyrone; Freund's Adjuvant; Indomethacin; Inflammation; Male; Mice; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain, Postoperative; Postural Balance; Pyrazoles; Stomach Ulcer | 2008 |
Tolerance to non-opioid analgesics in PAG involves unresponsiveness of medullary pain-modulating neurons in male rats.
Topics: Action Potentials; Analgesics, Non-Narcotic; Animals; Aspirin; Dipyrone; Drug Tolerance; Male; Medulla Oblongata; Morphine; Narcotics; Neurons; Pain; Pain Measurement; Periaqueductal Gray; Rats; Reaction Time; Somatostatin | 2009 |
Effect of metamizol on morphine pharmacokinetics and pharmacodynamics after acute and subchronic administration in arthritic rats.
Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arthritis, Experimental; Dipyrone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Morphine; Rats; Rats, Wistar | 2010 |
Antinociceptive effect of methanol extract of Capparis ovata in mice.
Topics: Acetic Acid; Analgesics; Animals; Capparis; Dipyrone; Dose-Response Relationship, Drug; Flowers; Hot Temperature; Injections, Intraperitoneal; Male; Medicine, Traditional; Methanol; Mice; Morphine; Naloxone; Pain; Pain Measurement; Plant Extracts; Reaction Time; Solvents; Turkey | 2010 |
[Chronic dizziness in a pain patient--pharmacogenomic identification of tramadol as cause].
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chemotherapy, Adjuvant; Cytochrome P-450 CYP2D6; Delayed-Action Preparations; Dipyrone; Dizziness; Drug Therapy, Combination; Genes, Duplicate; Humans; Male; Mesothelioma; Middle Aged; Morphine; Pain; Pain Measurement; Pain, Postoperative; Pleural Neoplasms; Rehabilitation Centers; Tramadol | 2010 |
Opioid sensitivity of nucleus raphe magnus ater analgesia by nonsteroidal anti-inflammatory drugs.
Topics: Analgesia; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Drug Interactions; Drug Tolerance; Ketorolac; Male; Microinjections; Morphine; Naloxone; Nociceptors; Pain; Periaqueductal Gray; Piroxicam; Raphe Nuclei; Rats; Spinal Cord | 2011 |
Myometrial response to neurotropic and musculotropic spasmolytic drugs in an extracorporeal perfusion model of swine uteri.
Topics: Animals; Atropine; Benzilates; Butylscopolammonium Bromide; Chelidonium; Dipyrone; Female; In Vitro Techniques; Meperidine; Models, Animal; Morphine; Myometrium; Parasympatholytics; Plant Extracts; Swine; Uterine Contraction; Uterus | 2011 |
Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their zinc(II) complexes.
Topics: Acetic Acid; Aldehydes; Analgesics; Animals; Anti-Inflammatory Agents; Coordination Complexes; Crystallography, X-Ray; Dipyrone; Female; Formaldehyde; Hot Temperature; Hydrazones; Indomethacin; Inflammation; Magnetic Resonance Spectroscopy; Male; Mice; Morphine; Pain; Pain Measurement; Peritonitis; Zinc; Zymosan | 2011 |
Epidural and opioid analgesia following the Nuss procedure.
Topics: Adolescent; Amides; Analgesia, Epidural; Analgesics, Opioid; Analysis of Variance; Blood Pressure; Dipyrone; Female; Fentanyl; Funnel Chest; Heart Rate; Humans; Male; Minimally Invasive Surgical Procedures; Morphine; Pain Measurement; Pain, Postoperative; Parental Consent; Ropivacaine; Statistics, Nonparametric | 2011 |
High-performance liquid chromatographic assay for metamizol metabolites in rat plasma: application to pharmacokinetic studies.
Topics: Aminopyrine; Ampyrone; Animals; Calibration; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Dipyrone; Drug Interactions; Male; Morphine; Rats; Rats, Wistar; Solid Phase Extraction | 2012 |
Antinociceptive and anti-inflammatory activities of crude methanolic extract of red alga Bryothamnion triquetrum.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Dipyrone; Female; Indomethacin; Leukocytes; Male; Methanol; Mice; Morphine; Pain; Peritonitis; Plant Extracts; Rhodophyta; Zymosan | 2012 |
Effects of reference analgesics and psychoactive drugs on the noxious heat threshold of mice measured by an increasing-temperature water bath.
Topics: Analgesics; Animals; Diazepam; Diclofenac; Dipyrone; Dose-Response Relationship, Drug; Droperidol; Female; Hot Temperature; Mice; Morphine; Motor Activity; Psychotropic Drugs; Sensory Thresholds; Thermosensing | 2013 |
Pain management during radiotherapy and radiochemotherapy in oropharyngeal cancer patients: single-institution experience.
Topics: Acetaminophen; Adult; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Chemoradiotherapy; Chemoradiotherapy, Adjuvant; Cisplatin; Dipyrone; Drug Combinations; Female; Fentanyl; Follow-Up Studies; Humans; Male; Middle Aged; Morphine; Neoplasm Staging; Oropharyngeal Neoplasms; Pain; Pain Management; Radiotherapy, Adjuvant; Radiotherapy, High-Energy; Retrospective Studies; Tramadol | 2015 |
Pharmacokinetics and pharmacodynamics of metamizol in co-administration with morphine under acute and chronic treatments in arthritic rats.
Topics: Analgesics; Analgesics, Opioid; Animals; Dipyrone; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Drug Tolerance; Male; Morphine; Pain; Pain Measurement; Rats; Rats, Wistar | 2017 |
Postoperative pain after tonsillectomy - the value of standardized analgesic treatment protocols.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Dipyrone; Female; Humans; Ibuprofen; Male; Morphine; Pain Management; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Tramadol | 2020 |
Stability evaluation of morphine, hydromorphone, metamizole and esketamine containing analgesic mixtures applied for patient-controlled analgesia in hospice and palliative care.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Dipyrone; Hospices; Humans; Hydromorphone; Ketamine; Morphine; Palliative Care | 2022 |
Efficacy and safety in ketamine-guided prehospital analgesia for abdominal pain.
Topics: Abdominal Pain; Adult; Aged; Analgesia; Analgesics; Analgesics, Opioid; Dipyrone; Emergency Medical Services; Female; Fentanyl; Humans; Ketamine; Middle Aged; Morphine; Pain Measurement; Retrospective Studies | 2022 |