dipyrone has been researched along with ampyrone in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (25.58) | 18.7374 |
| 1990's | 8 (18.60) | 18.2507 |
| 2000's | 7 (16.28) | 29.6817 |
| 2010's | 12 (27.91) | 24.3611 |
| 2020's | 5 (11.63) | 2.80 |
| Authors | Studies |
|---|---|
| Bisogno, T; Cascio, MG; Di Marzo, V; Imming, P; Lichtman, AH; Nüsing, R; Podlewski, A; Rogosch, T; Schlosburg, J; Sinning, C; Watzer, B | 1 |
| Granit, L; Levy, M; Zylber-Katz, E | 2 |
| Bacracheva, N; Badian, M; Verho, M; Vlahov, V | 1 |
| Becker, EW; Berg, PA; Federmann, G; Penschuck, C; Tautorat, H | 1 |
| Funae, Y; Imaoka, S; Inoue, K | 1 |
| Burckart, GJ; D'Souza, MJ; Venkataramanan, R; Zemaitis, MA | 1 |
| Drexler, R; Levy, M; Matzner, Y | 1 |
| Flusser, D; Granit, L; Levy, M; Zylber-Katz, E | 1 |
| Altrogge, G; Pola, W; Sistovaris, N; Wolhoff, H | 1 |
| Fujimori, K; Inoue, K; Mizokami, K; Omori, Y; Sunouchi, M; Takanaka, A | 1 |
| Pola, W; Sistovaris, N; Wolhoff, H | 1 |
| Sakai, A; Tanimura, A | 1 |
| Haustein, KO; Hüller, G | 1 |
| Carretero, I; Laserna, JJ; Vadillo, JM | 1 |
| Caraco, Y; Granit, L; Levy, M; Zylber-Katz, E | 2 |
| Dennhardt, R; Gramm, HJ; Heinemeyer, G; Roots, I; Simgen, W | 1 |
| Böcker, R; Geisslinger, G; Levy, M | 1 |
| Caraco, Y; Cohen, O; Granit, L; Levy, M; Zylber-Katz, E | 1 |
| Caraco, Y; Granit, L; Levy, M; Safadi, R; Zylber-Katz, E | 1 |
| Bianchi, L; Büchtemann, A; Herdeg, C; Hilt, F; Klein, R | 1 |
| Collares, EF; Vinagre, AM | 5 |
| Brenneis, C; Geisslinger, G; Michaelis, M; Pierre, SC; Schmidt, R; Scholich, K | 1 |
| Agüera, A; Fernández-Alba, AR; Gómez, MJ; Mezcua, M; Sirtori, C | 1 |
| Calzadilla, PC; Cortés-Arroyo, AR; Domínguez-Ramírez, AM; Gómez-Hernández, M; Hurtado Y de la Peña, M; López, JR; López-Muñoz, FJ | 1 |
| Kamiyama, N; Kayama, H; Kimura, T; Ma, JS; Machimura, S; Ohshima, J; Saiga, H; Sasai, M; Takeda, K; Ueda, Y; Yamamoto, M | 1 |
| Aguiar, FA; Assis, DC; Clososki, GC; de Melo, MC; de Souza, GE; Ferreira, SH; Jabor, VA; Kalapothakis, E; Malvar, Ddo C; Vaz, Ade L | 1 |
| Agúndez, JA; Andreu, I; Ariza, A; Blanca, M; Blanca-Lopez, N; García-Martín, E; Mayorga, C; Montañez, MI; Perkins, J; Salas, M; Torres, MJ | 1 |
| Burmańczuk, A; Giorgi, M; Grabowski, T; Kowalski, C; Owen, H | 1 |
| Chea, B; Giorgi, M; Kim, TW; Lebkowska-Wieruszewska, B; Owen, H; Poapolathep, A | 1 |
| De Vito, V; Giorgi, M; Kim, TW; Lisowski, A; Owen, H; Poapolathep, A; Łebkowska-Wieruszewska, B | 1 |
| Abilova, Z; Giorgi, M; Kim, TW; Lisowski, A; Owen, H; Poapolathep, A; Sitovs, A; Łebkowska-Wieruszewska, B | 1 |
| Collares, EF; Troncon, LEA | 1 |
| de Azevedo, WF; Russo, S | 1 |
| Baumgartner, C; Behrendt-Wippermann, M; Brandl, J; Feist, M; Fux, D; Metzner, M; von Thaden, A | 1 |
| Almeida, LD; Badenoch, B; Beatriz, A; Cristina Toffoli-Kadri, M; da Silva Gomes, R; da Silva Júnior, EN; da Silveira, IOMF; Fernandes, J; Hortelan, CRW; Janaína de Campos, L; Juliano Oliveira, R; Martins, ACF; Mohammad, J; Moslaves, ISB; Muller, JAI; Okuyama, TT | 1 |
| Araújo-Silva, G; Arcoverde, KN; de Macêdo, LB; de Paiva, ALC; de Paula, VV; Fernandes, NS; Mouta, AN; Nunes, TL; Urizar, JTP | 1 |
| Alves, LSA; Araújo-Silva, G; Arcoverde, KN; Cavalcante, JM; de Paula, VV; Jurema, AP; Maranhão, ACPM; Urizar, JTP | 1 |
2 review(s) available for dipyrone and ampyrone
| Article | Year |
|---|---|
Effects of dipyrone on the digestive tract.
Topics: Ampyrone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Autonomic Nerve Block; Dipyrone; Gastric Emptying; Rats; Rats, Wistar | 2019 |
Computational Analysis of Dipyrone Metabolite 4-Aminoantipyrine As A Cannabinoid Receptor 1 Agonist.
Topics: Ampyrone; Analgesics; Cannabinoid Receptor Agonists; Cannabinoids; Dipyrone | 2020 |
5 trial(s) available for dipyrone and ampyrone
| Article | Year |
|---|---|
Pharmacokinetics of metamizol metabolites in healthy subjects after a single oral dose of metamizol sodium.
Topics: Administration, Oral; Adult; Aminopyrine; Ampyrone; Antipyrine; Dipyrone; Humans; Male; Pyrazolones; Random Allocation; Time Factors | 1990 |
Cerebrospinal fluid and plasma concentrations of dipyrone metabolites after a single oral dose of dipyrone.
Topics: Administration, Oral; Adult; Aged; Aminopyrine; Ampyrone; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Dipyrone; Double-Blind Method; Female; Humans; Male; Middle Aged; Pyrazolones; Spinal Puncture | 1998 |
Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis-B virus does not occur in rapid acetylators.
Topics: Acetylation; Adult; Algorithms; Aminopyrine; Ampyrone; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Carrier State; Dipyrone; Female; Half-Life; Hepatitis B virus; Humans; Male; Metabolic Clearance Rate; Models, Biological; Pyrazolones | 2001 |
Pharmacokinetic profiles of the two major active metabolites of metamizole (dipyrone) in cats following three different routes of administration.
Topics: Administration, Oral; Ampyrone; Analgesics; Animals; Cats; Cross-Over Studies; Dipyrone; Injections, Intramuscular; Injections, Intravenous; Male | 2018 |
Pharmacokinetic profiles of the active metamizole metabolites after four different routes of administration in healthy dogs.
Topics: Administration, Oral; Administration, Rectal; Ampyrone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Cross-Over Studies; Dipyrone; Dogs; Female; Half-Life; Injections, Intramuscular; Injections, Intravenous; Molecular Structure | 2018 |
36 other study(ies) available for dipyrone and ampyrone
| Article | Year |
|---|---|
Novel bioactive metabolites of dipyrone (metamizol).
Topics: Administration, Oral; Aminopyridines; Ampyrone; Animals; Central Nervous System; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dipyrone; Enzyme Activation; Mice; Mice, Inbred C57BL; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reference Standards; Spectrometry, Mass, Electrospray Ionization | 2012 |
Formation and excretion of dipyrone metabolites in man.
Topics: Administration, Oral; Adult; Aminopyrine; Ampyrone; Chromatography, High Pressure Liquid; Dipyrone; Half-Life; Humans; Male; Pyrazolones | 1992 |
[Demonstration by lymphocyte transformation test of the allergic genesis in a case of acute hepatitis].
Topics: Acute Disease; Alanine Transaminase; Alkaline Phosphatase; Aminopyrine; Ampyrone; Aspartate Aminotransferases; Bilirubin; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Dipyrone; Drug Hypersensitivity; gamma-Glutamyltransferase; Humans; Lymphocyte Activation; Male; Middle Aged; Time Factors | 1988 |
Aminopyrine metabolism by multiple forms of cytochrome P-450 from rat liver microsomes: simultaneous quantitation of four aminopyrine metabolites by high-performance liquid chromatography.
Topics: Aminopyrine; Ampyrone; Animals; Antipyrine; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dipyrone; Female; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Pyrazolones; Rats; Rats, Inbred Strains | 1988 |
Simple high-performance liquid chromatographic method for simultaneous determination of aminopyrine and its metabolites.
Topics: Aminopyrine; Ampyrone; Animals; Chromatography, High Pressure Liquid; Dipyrone; Half-Life; Injections, Intravenous; Male; Microsomes, Liver; Pyrazolones; Rabbits | 1987 |
Plasma protein binding of dipyrone metabolites in man.
Topics: Acetaminophen; Adult; Aminopyrine; Ampyrone; Aspirin; Blood Proteins; Dipyrone; Female; Humans; Ibuprofen; Male; Protein Binding; Pyrazolones | 1985 |
Effect of dipyrone, acetylsalicylic acid and acetaminophen on human neutrophil chemotaxis.
Topics: Acetaminophen; Aminopyrine; Ampyrone; Aspirin; Chemotaxis, Leukocyte; Dipyrone; Dose-Response Relationship, Drug; Humans; Neutrophils; Pyrazolones | 1984 |
Plasma kinetics of dipyrone metabolites in rapid and slow acetylators.
Topics: Acetylation; Adult; Aminopyrine; Ampyrone; Chemical Phenomena; Chemistry; Dipyrone; Female; Half-Life; Humans; Kinetics; Male; Pyrazolones | 1984 |
[Metamizol--acute overdose with suicidal intent].
Topics: Adolescent; Aminopyrine; Ampyrone; Biotransformation; Dipyrone; Female; Furosemide; Humans; Pyrazolones; Suicide, Attempted | 1983 |
Simultaneous determination of aminopyrine hydroxylation and aminopyrine N-demethylation in liver microsomes by high-performance liquid chromatography.
Topics: Aminopyrine; Ampyrone; Animals; Biotransformation; Chromatography, High Pressure Liquid; Dipyrone; Hydroxylation; Methylation; Microsomes, Liver; Pyrazolones; Rats | 1983 |
Thin-layer chromatographic determination of major metamizole metabolites in serum and urine.
Topics: Adolescent; Aminopyrine; Ampyrone; Chromatography, Thin Layer; Dipyrone; Female; Half-Life; Humans; Kinetics; Pyrazolones | 1983 |
Mutagenicity of N-nitroso compounds formed by the reaction of sulpyrine with nitrite; effects of cysteine and its derivatives.
Topics: Aminopyrine; Ampyrone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Cysteine; Dipyrone; Glutathione; Male; Mutagens; Nitrites; Nitrosamines; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1982 |
[Quantitative thin-layer chromatographic estimation of aminophenazone (I.N.N.), 4-methylaminophenazone and 4-aminophenazone in plasma (author's transl)].
Topics: Aminopyrine; Ampyrone; Antipyrine; Chromatography, Thin Layer; Dipyrone; Humans; Pyrazolones; Time Factors | 1981 |
Determination of antipyrine metabolites in human plasma by solid-phase extraction and micellar liquid chromatography.
Topics: Aminopyrine; Ampyrone; Antipyrine; Chromatography, Liquid; Dipyrone; Humans; Micelles; Pyrazolones; Reproducibility of Results | 1995 |
Dipyrone metabolism in liver disease.
Topics: Acetylation; Administration, Oral; Adult; Aged; Aged, 80 and over; Ampyrone; Case-Control Studies; Dipyrone; Female; Half-Life; Humans; Liver Cirrhosis; Male; Middle Aged | 1995 |
The kinetics of metamizol and its metabolites in critical-care patients with acute renal dysfunction.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Ampyrone; Critical Care; Dipyrone; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pyrazolones; Shock, Septic | 1993 |
Validity of saliva samples for the estimation of dipyrone metabolites pharmacokinetics.
Topics: Acetylation; Adult; Aminopyrine; Ampyrone; Dipyrone; Female; Half-Life; Humans; Male; Phenotype; Pyrazolones; Saliva | 1993 |
High-performance liquid chromatographic analysis of dipyrone metabolites to study their formation in human liver microsomes.
Topics: Aminopyrine; Ampyrone; Chromatography, High Pressure Liquid; Dipyrone; Humans; Microsomes, Liver; Pyrazolones; Spectrophotometry, Ultraviolet | 1996 |
Allergic cholestatic hepatitis and exanthema induced by metamizole: verification by lymphocyte transformation test.
Topics: Aged; Aminopyrine; Ampyrone; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Dipyrone; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Lymphocyte Activation; Male; Pyrazolones | 2002 |
Evidence of the effect of dipyrone on the central nervous system as a determinant of delayed gastric emptying observed in rats after its administration.
Topics: Ampyrone; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System; Dipyrone; Dose-Response Relationship, Drug; Gastric Emptying; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Time Factors; Vagotomy; Vagus Nerve | 2003 |
Inhibition of cyclooxygenases by dipyrone.
Topics: Ampyrone; Animals; Cyclooxygenase Inhibitors; Dipyrone; Heme; Hydrogen Peroxide; Iron; Male; Rats; Rats, Sprague-Dawley | 2007 |
Effect of 4-aminoantipyrine on gastric compliance and liquid emptying in rats.
Topics: Ampyrone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Dose-Response Relationship, Drug; Gastric Emptying; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Time Factors; Vagus Nerve | 2007 |
Photodegradation study of three dipyrone metabolites in various water systems: identification and toxicity of their photodegradation products.
Topics: Aminopyrine; Ampyrone; Animals; Daphnia; Dipyrone; Humans; Kinetics; Mass Spectrometry; Molecular Weight; Photolysis; Solutions; Time Factors; Toxicity Tests; Water; Water Pollutants, Chemical | 2008 |
Phenylpyrazolone derivatives inhibit gastric emptying in rats by a capsaicin-sensitive afferent pathway.
Topics: Afferent Pathways; Ampyrone; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Capsaicin; Dipyrone; Dose-Response Relationship, Drug; Gastric Emptying; Male; Rats; Rats, Wistar | 2009 |
High-performance liquid chromatographic assay for metamizol metabolites in rat plasma: application to pharmacokinetic studies.
Topics: Aminopyrine; Ampyrone; Animals; Calibration; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Dipyrone; Drug Interactions; Male; Morphine; Rats; Rats, Wistar; Solid Phase Extraction | 2012 |
CREBH determines the severity of sulpyrine-induced fatal shock.
Topics: Ampyrone; Animals; Aryl Hydrocarbon Hydroxylases; Cyclic AMP Response Element-Binding Protein; Cytochrome P-450 CYP2B1; Cytochrome P450 Family 2; Dipyrone; Disease Models, Animal; Endoplasmic Reticulum Stress; Gene Expression Regulation; Liver; Male; Mice; Mice, Knockout; Promoter Regions, Genetic; RNA Interference; Severity of Illness Index; Shock; Steroid Hydroxylases; Transcriptional Activation | 2013 |
Evidence for the involvement of peripheral β-adrenoceptors in delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats.
Topics: Adrenergic Antagonists; Ampyrone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Dipyrone; Gastric Emptying; Infusions, Intraventricular; Male; Phenolsulfonphthalein; Prazosin; Propranolol; Rats, Wistar; Receptors, Adrenergic, beta; Yohimbine | 2013 |
Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever.
Topics: Ampyrone; Animals; Antipyretics; Body Temperature; Dinoprostone; Dipyrone; Fever; Hypothalamus; Hypothermia; Indomethacin; Lipopolysaccharides; Male; Prodrugs; Rats, Wistar; Scorpion Venoms | 2014 |
Effect of selective β-adrenoceptor blockade and surgical resection of the celiac-superior mesenteric ganglion complex on delayed liquid gastric emptying induced by dipyrone, 4-aminoantipyrine, and antipyrine in rats.
Topics: Adrenergic beta-Antagonists; Ampyrone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Atenolol; Butoxamine; Dipyrone; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Ganglionectomy; Gastric Emptying; Male; Models, Animal; Propanolamines; Rats, Wistar; Receptors, Adrenergic, beta; Sympathetic Nervous System | 2016 |
Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole.
Topics: Adult; Aged; Aminopyrine; Ampyrone; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Basophil Degranulation Test; Basophils; Biotransformation; Case-Control Studies; Dipyrone; Female; Humans; Male; Middle Aged; Pilot Projects; Primary Cell Culture | 2016 |
Pharmacokinetic investigations of the marker active metabolites 4-methylamino-antipyrine and 4-amino-antipyrine after intramuscular injection of metamizole in healthy piglets.
Topics: Ampyrone; Animals; Area Under Curve; Dipyrone; Half-Life; Male; Molecular Structure; Swine | 2016 |
Pharmacokinetic profiles of metamizole (dipyrone) active metabolites in goats and its residues in milk.
Topics: Ampyrone; Analgesics; Animals; Antipyrine; Dipyrone; Drug Residues; Female; Goats; Injections, Intramuscular; Injections, Intravenous; Milk | 2018 |
Pharmacokinetics of metamizole (dipyrone) as an add-on in calves undergoing umbilical surgery.
Topics: Ampyrone; Analgesics; Animals; Cattle; Dipyrone; Ketamine; Xylazine | 2022 |
Design, synthesis and in vivo evaluation of 1,4-dioxo-2-butenyl aryl amine derivatives as a promising anti-inflammatory drug prototype.
Topics: Amines; Ampyrone; Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dipyrone; Edema; Humans; Inflammation; Pain | 2022 |
Pharmacokinetic profiles of the two major active metabolites of metamizole, 4-methylaminoantipyrine (MAA) and 4-aminoantipyrine (AA), after intravenous injection in cats.
Topics: Ampyrone; Animals; Cats; Chromatography, Liquid; Dipyrone; Injections, Intravenous; Tandem Mass Spectrometry | 2023 |
Pharmacotherapeutic monitoring of dipyrone in northeastern Brazilian donkeys (Equus asinus).
Topics: Ampyrone; Animals; Brazil; Dipyrone; Equidae; Male; Tandem Mass Spectrometry | 2023 |