dipyridamole has been researched along with thioinosine in 163 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (42.94) | 18.7374 |
| 1990's | 56 (34.36) | 18.2507 |
| 2000's | 34 (20.86) | 29.6817 |
| 2010's | 3 (1.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Dalske, HF; Scholar, EM | 1 |
| Bergfeld, GR; Forrester, T | 1 |
| Aran, JM; Plagemann, PG | 1 |
| Cass, CE; Janowska-Wieczorek, A; King, KM; Montaño, JT | 1 |
| Hammond, JR; Jones, KW | 1 |
| Cunha, RA; Sebastião, AM | 1 |
| Dagnino, L; Paterson, AR | 1 |
| Finney, KJ; Harris, AL; Ince, P; Moorghen, M; Watson, AJ | 1 |
| Van Belle, H; Ver Donck, K; Wynants, J | 1 |
| Lieberman, M; Wagenknecht, B | 1 |
| Mitsumoto, Y; Mohri, T; Ohkubo, T | 1 |
| August, EM; Birks, EM; Prusoff, WH | 1 |
| Gengenbacher, HM; Holstege, A; Hoppmann, J; Jehle, L | 1 |
| Plagemann, PG | 2 |
| Granger, HJ; Meininger, CJ | 1 |
| Handschumacher, RE; Palatini, P; Palú, G; Parolin, C; Stefanelli, S | 1 |
| Averett, DR; Prus, KL; Zimmerman, TP | 1 |
| Delicado, EG; Miras-Portugal, MT; Ribeiro, JA; Rodrigues, A; Sebastiao, AM; Sen, RP | 1 |
| Fideu, MD; Miras-Portugal, MT; Torres, M | 1 |
| Baldy, WJ; Shank, RP | 1 |
| Chan, TC; Hom, DK; Howell, SB; Sanga, R; Vick, JS | 1 |
| Bianchi, M; Magnani, M; Rossi, L; Stocchi, V | 1 |
| Plagemann, PG; Woffendin, C | 4 |
| Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
| Beck, J; Ullman, B | 1 |
| Christopherson, RI; Gero, AM; O'Sullivan, WJ; Scott, HV | 1 |
| Gero, AM | 1 |
| Custers, AF; Hoos, B; Ijzerman, AP; Thedinga, KH; Van Belle, H | 1 |
| Clanachan, AS; Parkinson, FE | 1 |
| Hammond, JR; Johnstone, RM | 1 |
| Belzer, I; Friedberg, I; Huang, NN; Lane, E; Lustig, KD; Weisman, GA | 1 |
| Coons, T; McCartan, K; Rockwell, S; Ullman, B | 1 |
| Geiger, JD; Johnston, ME | 1 |
| Pisoni, RL; Thoene, JG | 1 |
| Hammond, JR | 1 |
| Belt, JA; Noel, LD | 1 |
| Bukoski, RD; Sparks, HV | 1 |
| Jarvis, SM; Young, JD | 2 |
| Plagemann, PG; Woffendin, C; Wohlhueter, RM | 1 |
| Daval, JL; Deckert, J; Marangos, PJ; Morgan, PF; Nakajima, T | 1 |
| Bisserbe, JC; Deckert, J; Klein, E; Marangos, PJ | 1 |
| Wheeler, CP; Yudilevich, DL | 1 |
| Brun-Marmillon, J; Claustrat, B; Collin, JP; Falcón, J | 1 |
| Joost, HG; Steinfelder, HJ | 1 |
| Deckert, J; Marangos, PJ; Morgan, PF | 1 |
| Harik, SI; Kalaria, RN | 2 |
| Jarvis, SM; Lee, CW | 1 |
| Agarwal, KC; Dawicki, DD; Parks, RE | 2 |
| Mohrman, DE | 1 |
| Delicado, EG; Miras-Portugal, MT; Torres, M | 1 |
| Geiger, JD; Johnston, ME; Yago, V | 1 |
| Aronow, B; Ullman, B | 1 |
| Aronow, B; Hollingsworth, P; McCartan, K; Patrick, J; Toll, D; Ullman, B | 1 |
| Cha, S; el Kouni, MH | 1 |
| Cha, S; el Kouni, MH; Messier, NJ | 1 |
| Kraupp, M; Plagemann, PG | 1 |
| Jarvis, SM | 1 |
| Belt, JA; Gati, WP; Jakobs, ES; Jarvis, SM; Paterson, AR; Young, JD | 1 |
| Deckert, J; Marangos, PJ | 1 |
| Shi, MM; Young, JD | 1 |
| Plagemann, PG; Wohlhueter, RM | 2 |
| Sanderson, G; Scholfield, CN | 1 |
| Jarvis, SM; Ng, AS | 1 |
| Clanachan, AS; Hammond, JR | 3 |
| Belloni, FL; Elkin, PL; Giannotto, B | 1 |
| Clanachan, AS; Williams, EF | 1 |
| Ghai, G; Mustafa, SJ | 1 |
| Belt, JA | 1 |
| Chen, SF; Parks, RE; Stoeckler, JD | 1 |
| Carson, DA; Iizasa, T; Kubota, M | 1 |
| Finkel, MS; Marangos, PJ; Maturi, MF; Patel, J; Patterson, RE; Verma, A | 1 |
| Baer, HP; Vriend, R | 1 |
| Janmohamed, SN; Jarvis, SM; Young, JD | 1 |
| Lee, CM; Shi, MM; Wu, JS; Young, JD | 1 |
| Belt, JA; Gati, WP; Jarvis, SM; Paterson, AR; Young, JD | 1 |
| Brown, WE; Plagemann, PG; Wohlhueter, RM | 1 |
| Jarvis, SM; McBride, D; Young, JD | 1 |
| Ansay, M; Archibald, AL; Harkness, RA; Jarvis, SM; Simmonds, RJ; Young, JD | 1 |
| Cass, CE; Dahlig, E; Lau, EY; Paterson, AR | 1 |
| Delander, GE; Keil, GJ | 1 |
| Collier, B; Tandon, A | 1 |
| Afifi Afifi, M; Handschumacher, RE; Joiner, KA; Pizzorno, G; Schwab, JC | 1 |
| Sasvari-Szekely, M; Solymossy, M; Staub, M; Szikla, K | 1 |
| Barankiewicz, J; Kossenjans, W; Rymaszewski, Z; Uyesaka, J | 1 |
| Foga, IO; Geiger, JD; Gu, JG; Parkinson, FE | 1 |
| Hada, J; Hayashi, Y; Kaku, T | 1 |
| Belardinelli, L; Dennis, DM; Shryock, JC | 1 |
| Casillas, T; Delicado, EG; Miras-Portugal, MT; Sen, RP | 1 |
| Savić, V; Stefanović, V; Vlahović, P | 1 |
| Bereznai, B; Deckert, J; Fritze, J; Hennemann, A; Marangos, PJ; Riederer, P; Vock, R | 1 |
| Lee, CW | 1 |
| Böhm, D; Böhm, M; Erdmann, E; Müller-Ehmsen, J; Reichart, B; Reichenspurner, H; Schwinger, RH; Weinhold, C | 1 |
| Goz, B; Jeffs, L | 1 |
| Bols, NC; Ganassin, RC; Rabgey, TF; Tran, QH | 1 |
| Jones-Humble, SA; Morgan, PF | 1 |
| Gonçalves, J; Queiroz, G | 1 |
| Sawynok, J; Sweeney, MI; White, TD | 1 |
| Griffith, DA; Jarvis, SM | 1 |
| Cass, CE; Fang, X; Mowles, DA; Parkinson, FE; Young, JD | 1 |
| Geiger, JD; Gu, JG; Nath, A | 1 |
| Hada, J; Hayashi, Y; Kaku, T; Morimoto, K; Nagai, K | 1 |
| Geiger, JD; Mukherjee, K; Parkinson, FE | 1 |
| Williams, EF | 2 |
| Brown, LG; Chu, TC; Manor, EL; Socci, RR; Walker, CE; Williams, EF | 1 |
| Cook, MA; McDonald, TJ; Moneta, NA | 1 |
| Baldwin, SA; Cass, CE; Griffiths, M; Muzyka, WR; Ng, AM; Yao, SY; Young, JD | 1 |
| Kalsi, KK; Smolenski, RT; Yacoub, MH | 2 |
| Baldwin, SA; Cass, CE; Griffiths, M; Ng, AM; Sundaram, M; Yao, SY; Young, JD | 1 |
| Bockaert, J; Manzoni, O; Pujalte, D; Williams, J | 1 |
| Belt, JA; Cass, CE; Crawford, CR; Mackey, JR; Mani, RS; Mowles, D; Selner, M; Young, JD | 1 |
| Detke, S | 1 |
| Cseppentö, A; Kovács, P; Nagy, E; Szabó, JZ; Szentmiklósi, AJ; Ujfalusi, A | 1 |
| Baldwin, SA; Cass, CE; Hogue, DL; Mani, RS; Sundaram, M; Vickers, MF; Young, JD | 1 |
| Deussen, A; Kelm, M; Schäfer, S; Stappert, M | 1 |
| Diao, L; Dunwiddie, TV | 1 |
| Ahmad, I; Al-Katib, AM; Beck, FW; Liu, KZ; Mantsch, HH; Mohammad, RM; Wall, NR | 1 |
| Mo, ZP; Sherali, A; Tse, CM; Ward, JL | 1 |
| Camarasa, J; Camins, A; Escubedo, E; Jiménez, A; Lladó, S; Pallàs, M; Pubill, D | 1 |
| Baldwin, SA; Cass, CE; Hyde, RJ; McConkey, GA; McRobert, L; Parker, MD; Yao, SY; Young, JD | 1 |
| Dhalla, AK; Dodam, JR; Johnson, LR; Jones, AW; Laughlin, MH; Magliola, L; Rubin, LJ | 1 |
| Baldwin, SA; Carpenter, P; Cass, CE; Chen, XZ; Graham, K; Hyde, RJ; Karpinski, E; Loewen, SK; Mowles, DA; Ng, AM; Ritzel, MW; Ritzel, RG; Smith, KM; Yao, SY; Young, JD | 1 |
| Caldeiro, RM; Choi, DS; Diamond, I; Gordon, AS; Handa, M; Messing, RO | 1 |
| Curtin, NJ; Marshman, E; Newell, DR; Taylor, GA; Thomas, HD | 1 |
| Baldwin, SA; Cass, CE; Ng, AM; Vickers, MF; Visser, F; Young, JD | 1 |
| Boyer, CR; Karjian, PL; Neuteboom, ST; Pegram, M; Wahl, GM | 1 |
| Bernard, EA; de Souza, LF; Gelain, DP | 1 |
| Christie, MJ; Hack, SP; Vaughan, CW | 1 |
| Al Safarjalani, ON; El Kouni, MH; Naguib, FN | 1 |
| Bilan, PJ; Coe, IR; Shuralyova, I; Sweeney, G; Tajmir, P | 1 |
| Endres, CJ; Sengupta, DJ; Unadkat, JD | 1 |
| SenGupta, DJ; Unadkat, JD | 1 |
| Bernard, EA; De Souza, LF; Gelain, DP; Jardim, FR; Moreira, JC; Ribeiro, GR; Zim, M | 1 |
| Archer, RG; Hammond, JR; McConnell, K; Stolk, M | 1 |
| Conde, SV; Monteiro, EC | 1 |
| Archer, RG; Hammond, JR; Pitelka, V | 1 |
| Collins, M; Graves, LM; Huang, M; Wang, Y | 1 |
| Endres, CJ; Unadkat, JD | 1 |
| Parkinson, FE; Xiong, W; Zamzow, CR | 1 |
| Ahmad, I; Ahmad, MU; Ali, SM; Chen, P; Chien, PY; Khan, AR; Sheikh, S | 1 |
| Dér, P; Gesztelyi, R; Juhász, B; Karsai, D; Szentmiklósi, AJ; Tósaki, A; Zsuga, J | 1 |
| Curigliano, G; Danesi, R; De Braud, F; De Cobelli, O; Del Tacca, M; Giovannetti, E; Mey, V; Nannizzi, S; Pece, S; Verweij, F | 1 |
| Hiura, T; Ishikawa, M; Kanno, S; Koiwai, K; Ohtake, T; Suzuki, H; Ujibe, M | 1 |
| Nagata, K; Nakahata, N; Ohkubo, S | 1 |
| Bone, DB; Hammond, JR | 1 |
| Berendt, RC; Brun, M; Cass, CE; Damaraju, D; Damaraju, VL; Kuzma, M; Mowles, D; Sawyer, MB | 1 |
| Baldwin, SA; Cass, CE; Damaraju, V; Paproski, RJ; Tackaberry, T; Visser, F; Young, JD; Zhang, J | 1 |
| Itoh, T; Kojima, D; Matsuoka, N; Mera, T; Nakano, M; Nitta, T; Yamashita, Y; Yasunami, Y | 1 |
| Bhuiyan, H; Bogason, A; Fotoohi, AK; Karim, H; Lafolie, P; Vitols, S | 1 |
| Bogo, MR; Bonan, CD; Capiotti, KM; da Costa Schaefer, I; Da Silva, RS; Frantz, JZ; Kist, LW; Menezes, FP; Siebel, AM | 1 |
| Chen, F; Han, X; Kuang, Y; Lei, Y; Li, Y; Liu, J; Peng, M; Wu, Y; Yang, X; Ye, M; Zhang, J; Zhao, X | 1 |
3 review(s) available for dipyridamole and thioinosine
| Article | Year |
|---|---|
Nucleoside and nucleobase transport in animal cells.
Topics: Adenine; Algorithms; Animals; Biological Transport; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Kinetics; Lidoflazine; Monosaccharide Transport Proteins; Nucleosides; Temperature; Thioinosine; Thionucleosides | 1988 |
Adenosine uptake site heterogeneity in the mammalian CNS? Uptake inhibitors as probes and potential neuropharmaceuticals.
Topics: Adenosine; Animals; Biological Transport; Brain; Dipyridamole; Erythrocytes; Nervous System; Thioinosine; Tumor Cells, Cultured | 1988 |
Nucleoside transport in animal cells.
Topics: Animals; Biological Transport, Active; Diazepam; Dilazep; Dipyridamole; Erythrocyte Membrane; Erythrocytes; Humans; Inosine; Kinetics; Membrane Proteins; Models, Molecular; Nucleosides; Papaverine; Species Specificity; Thioinosine; Uridine | 1983 |
1 trial(s) available for dipyridamole and thioinosine
| Article | Year |
|---|---|
In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients.
Topics: Administration, Intravesical; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Deoxycytidine Kinase; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Equilibrative Nucleoside Transporter 1; Excitatory Amino Acid Antagonists; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Glutamates; Guanine; Humans; Male; Middle Aged; Neoplasm Staging; Pemetrexed; Phosphoribosylglycinamide Formyltransferase; Phosphorylation; Proto-Oncogene Proteins c-akt; S Phase; Thioinosine; Thymidylate Synthase; Treatment Outcome; Urinary Bladder Neoplasms | 2006 |
159 other study(ies) available for dipyridamole and thioinosine
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Effect of purine compounds on the vascular responsiveness of bovine coronary and lingual arteries.
Topics: Adenine; Animals; Arteries; Blood Vessels; Cattle; Coronary Vessels; Dipyridamole; Drug Interactions; In Vitro Techniques; Purine Nucleosides; Purine Nucleotides; Thioinosine; Tongue | 1979 |
Release of ATP from human erythrocytes in response to a brief period of hypoxia and hypercapnia.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Adult; Aged; Carbon Dioxide; Cell Hypoxia; Cells, Cultured; Dipyridamole; Erythrocytes; Female; Humans; Male; Mesylates; Middle Aged; Models, Biological; Muscles; Niflumic Acid; Physical Exertion; Thioinosine | 1992 |
High-affinity, equilibrative nucleoside transporter of pig kidney cell line (PK-15).
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Carrier Proteins; Cell Line; Dipyridamole; Formycins; Gramicidin; Kidney; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Swine; Thioinosine | 1992 |
A comparison of the abilities of nitrobenzylthioinosine, dilazep, and dipyridamole to protect human hematopoietic cells from 7-deazaadenosine (tubercidin).
Topics: Adenosine; Colony-Forming Units Assay; Dilazep; Dipyridamole; Hematopoietic Stem Cells; Humans; Leukemia, Promyelocytic, Acute; Thioinosine; Tubercidin; Tumor Cells, Cultured | 1992 |
Heterogeneity of [3H]dipyridamole binding to CNS membranes: correlation with [3H]nitrobenzylthioinosine binding and [3H]uridine influx studies.
Topics: Animals; Biological Transport; Cerebral Cortex; Dipyridamole; Female; Filtration; Glass; Guinea Pigs; Male; Rabbits; Synaptosomes; Thioinosine; Tritium; Uridine | 1992 |
Extracellular metabolism of adenine nucleotides and adenosine in the innervated skeletal muscle of the frog.
Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Coformycin; Dipyridamole; In Vitro Techniques; Inosine Monophosphate; Kinetics; Muscles; Piperazines; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Thioinosine | 1991 |
Sodium-dependent and equilibrative nucleoside transport systems in L1210 mouse leukemia cells: effect of inhibitors of equilibrative systems on the content and retention of nucleosides.
Topics: Animals; Biological Transport; Dilazep; Dipyridamole; Formycins; Leukemia L1210; Mice; Nucleosides; Sodium; Thioinosine; Vidarabine; Vidarabine Phosphate | 1990 |
Organ culture as a model for investigating the effects of antimetabolites and nucleoside transport inhibitors on rodent colonic mucosa.
Topics: Animals; Biological Transport; Colon; Dipyridamole; DNA; Hydroxyurea; Intestinal Mucosa; Male; Models, Biological; Nucleosides; Organ Culture Techniques; Pyrimidines; Rats; Rats, Inbred Strains; Thioinosine; Thymidine; Time Factors; Tritium; Uridine | 1991 |
Comparison of the existing nucleoside transport inhibitors: in vitro and in vivo data.
Topics: Animals; Biological Transport; Dilazep; Dipyridamole; Epinephrine; Erythrocytes; Humans; In Vitro Techniques; Nucleosides; Phosphates; Piperazines; Rabbits; Thioinosine | 1991 |
Adenine nucleotide degradation in cultured chick heart muscle cells.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Dipyridamole; Glycolysis; Inosine; Myocardium; Oxidative Phosphorylation; Phosphorylation; Thioinosine | 1991 |
Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives.
Topics: 2-Chloroadenosine; Adenosine; Affinity Labels; Animals; Biological Transport; Caffeine; Cells, Cultured; Cytarabine; Dipyridamole; Embryo, Mammalian; Hippocampus; Kinetics; Neuroglia; Neurons; Pentoxifylline; Rats; Sodium; Theophylline; Thioinosine; Tritium; Xanthines | 1991 |
3'-Deoxythymidin-2'-ene permeation of human lymphocyte H9 cells by nonfacilitated diffusion.
Topics: Antiviral Agents; Cell Membrane Permeability; Cells, Cultured; Dideoxynucleosides; Diffusion; Dipyridamole; Humans; Kinetics; Lymphocytes; Octanols; Solubility; Stavudine; Thioinosine; Thymidine; Time Factors; Water | 1991 |
Facilitated diffusion and sodium-dependent transport of purine and pyrimidine nucleosides in rat liver.
Topics: Animals; Biological Transport; Diffusion; Dipyridamole; In Vitro Techniques; Liver; Male; Nucleosides; Perfusion; Purine Nucleosides; Pyrimidine Nucleosides; Rats; Rats, Inbred Strains; Sodium; Thioinosine; Uridine | 1991 |
Na(+)-dependent, active nucleoside transport in S49 mouse lymphoma cells and loss in AE-1 mutant deficient in facilitated nucleoside transport.
Topics: Aminoisobutyric Acids; Animals; Biological Transport, Active; Carrier Proteins; Dipyridamole; Formycins; Kinetics; Lymphoma; Membrane Proteins; Mice; Mutation; Nucleoside Transport Proteins; Nucleosides; Sodium; Thioinosine; Tumor Cells, Cultured | 1991 |
Mechanisms leading to adenosine-stimulated proliferation of microvascular endothelial cells.
Topics: Adenosine; Animals; Biomechanical Phenomena; Cell Division; Cyclic AMP; Dideoxyadenosine; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypoxanthine; Hypoxanthines; Inosine; Isomerism; Microcirculation; Molecular Weight; Thioinosine | 1990 |
Effect of herpes simplex virus type 1 infection on nucleoside transport in HeLa S3 cells.
Topics: Affinity Labels; Biological Transport; Cell Transformation, Viral; Dipyridamole; HeLa Cells; Humans; Kinetics; Methionine; Simplexvirus; Sucrose; Thioinosine; Thymidine | 1990 |
Transport and metabolism of 9-beta-D-arabinofuranosylguanine in a human T-lymphoblastoid cell line: nitrobenzylthioinosine-sensitive and -insensitive influx.
Topics: Arabinonucleosides; Biological Transport; Cell Division; Cell Line; Dilazep; Dipyridamole; Erythrocytes; Humans; Inosine; Kinetics; Leukemia-Lymphoma, Adult T-Cell; Purines; Ribonucleosides; Thioinosine; Tubercidin; Tumor Cells, Cultured | 1990 |
Effect of 5'-(N-ethylcarboxamido)adenosine on adenosine transport in cultured chromaffin cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; Biological Transport; Cells, Cultured; Chromaffin System; Colforsin; Dipyridamole; Kinetics; Nucleosides; Receptors, Purinergic; Thioinosine | 1990 |
All nucleoside transporters in bovine chromaffin cells are nitrobenzylthioinosine sensitive.
Topics: Adenosine; Adrenal Medulla; Animals; Carrier Proteins; Cattle; Cells, Cultured; Dipyridamole; Inosine; Thioinosine | 1990 |
Adenosine transport by rat and guinea pig synaptosomes: basis for differential sensitivity to transport inhibitors.
Topics: Adenosine; Animals; Biological Transport; Brain; Dipyridamole; Dogs; Female; Guinea Pigs; Hydrogen-Ion Concentration; Kinetics; Male; Membrane Potentials; Mice; Piperazines; Potassium; Rabbits; Rats; Rats, Inbred Strains; Sodium Chloride; Species Specificity; Synaptosomes; Thioinosine; Tissue Distribution | 1990 |
Dipyridamole enhancement of etoposide sensitivity.
Topics: Blood Proteins; Cell Survival; Cyclic AMP; Dipyridamole; Drug Synergism; Etoposide; Female; Humans; Protein Binding; Thioinosine; Tumor Cells, Cultured | 1989 |
2',3'-dideoxycytidine permeation of the human erythrocyte membrane.
Topics: Acquired Immunodeficiency Syndrome; Biological Transport; Diffusion; Dipyridamole; Erythrocyte Membrane; Hot Temperature; Humans; In Vitro Techniques; Thioinosine; Zalcitabine | 1989 |
Dideoxycytidine permeation and salvage by mouse leukemia cells and human erythrocytes.
Topics: Animals; Blood Proteins; Carrier Proteins; Dipyridamole; Erythrocytes; Humans; Hydroxyurea; Leukemia, Experimental; Membrane Proteins; Mice; Nucleoside Transport Proteins; Permeability; Solubility; Structure-Activity Relationship; Thioinosine; Uridine; Zalcitabine | 1989 |
Characterization of nucleoside transport during leukemic cell differentiation.
Topics: Biological Transport; Cell Differentiation; Cytarabine; Deoxycytidine Kinase; Dipyridamole; Humans; Inosine; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thioinosine; Tretinoin; Tumor Cells, Cultured | 1989 |
Expression of a novel high affinity purine base transport system in mutant mouse S49 cells does not require a functional nucleoside transporter.
Topics: Adenine; Animals; Biological Transport; Clone Cells; Dipyridamole; Dose-Response Relationship, Drug; Gene Expression; Guanine; Hybridization, Genetic; Hypoxanthine; Hypoxanthines; Inosine; Lymphoma; Mice; Mice, Inbred BALB C; Mutation; Phenotype; T-Lymphocytes; Thioinosine; Tumor Cells, Cultured | 1989 |
Antimalarial action of nitrobenzylthioinosine in combination with purine nucleoside antimetabolites.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Chromatography, High Pressure Liquid; Dilazep; Dipyridamole; Erythrocytes; Guanosine; Humans; Inosine; Molecular Structure; Nucleosides; Plasmodium falciparum; Thioinosine; Thionucleosides; Tubercidin | 1989 |
Na+-dependent and -independent transport of uridine and its phosphorylation in mouse spleen cells.
Topics: Animals; Biological Transport; Carrier Proteins; Dipyridamole; In Vitro Techniques; Kinetics; Membrane Proteins; Mice; Nucleoside Transport Proteins; Nucleosides; Phosphorylation; Purines; Pyrimidines; Sodium; Spleen; Thioinosine; Uridine | 1989 |
Induction of nucleoside transport sites into the host cell membrane of Babesia bovis infected erythrocytes.
Topics: Adenosine; Animals; Babesia; Binding Sites; Biological Transport; Cattle; Dilazep; Dipyridamole; Erythrocyte Membrane; Erythrocytes; Guanosine; Humans; Kinetics; Phloretin; Phlorhizin; Thioinosine; Thionucleosides; Verapamil | 1989 |
Inhibition of nucleoside transport by a new series of compounds related to lidoflazine and mioflazine.
Topics: Animals; Binding, Competitive; Cattle; Dipyridamole; Erythrocytes; In Vitro Techniques; Lidoflazine; Lung; Membranes; Nucleosides; Phosphates; Piperazines; Thioinosine | 1989 |
Heterogeneity of nucleoside transport inhibitory sites in heart: a quantitative autoradiographical analysis.
Topics: Animals; Autoradiography; Dipyridamole; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Inosine; Male; Myocardium; Nucleosides; Rats; Thioinosine; von Willebrand Factor | 1989 |
Solubilization and reconstitution of a nucleoside-transport system from Ehrlich ascites-tumour cells.
Topics: Adenosine; Animals; Binding Sites; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Membrane; Dipyridamole; Erythrocyte Membrane; Glucosides; Humans; Mice; Thioinosine; Tumor Cells, Cultured; Uridine | 1989 |
Growth inhibition of transformed mouse fibroblasts by adenine nucleotides occurs via generation of extracellular adenosine.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Biological Transport; Blood; Cell Division; Cell Line, Transformed; Dipyridamole; Fibroblasts; Mice; Nucleotidases; Thioinosine; Uridine Triphosphate | 1988 |
Genetic analysis of 2',3'-dideoxycytidine incorporation into cultured human T lymphoblasts.
Topics: Acquired Immunodeficiency Syndrome; Biological Transport; Cell Division; Cell Survival; Deoxycytidine; Deoxycytidine Kinase; Dipyridamole; Humans; Kinetics; Leukemia, Lymphoid; Mutation; Nucleosides; Phosphorylation; Phosphotransferases; T-Lymphocytes; Thioinosine; Tumor Cells, Cultured; Zalcitabine | 1988 |
Sodium-dependent uptake of nucleosides by dissociated brain cells from the rat.
Topics: Adenosine; Animals; Brain; Dilazep; Dipyridamole; Kinetics; Male; Nucleosides; Ouabain; Rats; Rats, Inbred Strains; Sodium; Thioinosine; Uridine | 1989 |
Detection and characterization of a nucleoside transport system in human fibroblast lysosomes.
Topics: Adenine; Adenosine; Amino Acid Transport Systems; Biological Transport; Carrier Proteins; Cell Line; Dipyridamole; Fibroblasts; Humans; Kinetics; Lysosomes; Nucleosides; Substrate Specificity; Thioinosine | 1989 |
Photoaffinity labelling of benzodiazepine receptors: lack of effect on ligand binding to the nucleoside transport system.
Topics: Affinity Labels; Animals; Benzodiazepinones; Biological Transport, Active; Carbolines; Cerebral Cortex; Dipyridamole; Flumazenil; Flunitrazepam; Guinea Pigs; Nucleosides; Photochemistry; Receptors, GABA-A; Thioinosine | 1985 |
Nucleoside transport in Walker 256 rat carcinosarcoma and S49 mouse lymphoma cells. Differences in sensitivity to nitrobenzylthioinosine and thiol reagents.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport; Carcinoma 256, Walker; Cell Line; Dipyridamole; Inosine; Kinetics; Lymphoma; Mice; Nucleosides; Rats; Sulfhydryl Compounds; Thioinosine; Uridine | 1985 |
Adenosine production and release by adult rat cardiocytes.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Transport, Active; Dinitrophenols; Dipyridamole; Heart; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Myocardium; Nucleotidases; Rats; Rats, Inbred Strains; Thioinosine | 1986 |
Nucleoside transport in rat erythrocytes: two components with differences in sensitivity to inhibition by nitrobenzylthioinosine and p-chloromercuriphenyl sulfonate.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport; Dipyridamole; Erythrocyte Membrane; Erythrocytes; Inosine; Kinetics; Male; Phenylmercury Compounds; Rats; Rats, Inbred Strains; Thioinosine; Uridine | 1986 |
Ontogeny of adenosine uptake sites in guinea pig brain: differential profile of [3H]nitrobenzylthioinosine and [3H]dipyridamole binding sites.
Topics: Aging; Animals; Cerebellum; Cerebral Cortex; Dipyridamole; Gestational Age; Guinea Pigs; Inosine; Kinetics; Membranes; Receptors, Purinergic; Thioinosine | 1988 |
Adenosine uptake sites in brain: regional distribution of putative subtypes in relationship to adenosine A1-receptors.
Topics: Adenosine; Animals; Binding Sites; Brain; Dipyridamole; Dogs; Guinea Pigs; In Vitro Techniques; Male; Receptors, Purinergic; Thioinosine; Tissue Distribution | 1988 |
Transport and metabolism of adenosine in the perfused guinea-pig placenta.
Topics: Adenosine; Animals; Biological Transport; Dipyridamole; Female; Guinea Pigs; Hypoxanthine; Hypoxanthines; Inosine; Maternal-Fetal Exchange; Placenta; Pregnancy; Thioinosine; Tritium; Uric Acid | 1988 |
Melatonin production in organ cultured chicken pineal: modulation by adenosine and its analogs.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Chickens; Colforsin; Deoxyadenosines; Dipyridamole; Melatonin; Organ Culture Techniques; Phenylisopropyladenosine; Pineal Gland; Thioinosine | 1988 |
Inhibition of insulin-stimulated glucose transport in rat adipocytes by nucleoside transport inhibitors.
Topics: 3-O-Methylglucose; Adipose Tissue; Animals; Biological Transport; Cytochalasin B; Dipyridamole; Guanosine; In Vitro Techniques; Inosine; Insulin; Kinetics; Male; Methylglucosides; Methylglycosides; Nucleosides; Papaverine; Rats; Rats, Inbred Strains; Thioinosine; Thionucleosides | 1988 |
Adenosine receptors and the nucleoside transporter in human brain vasculature.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Blood Proteins; Brain; Carrier Proteins; Cerebral Cortex; Choroid Plexus; Dipyridamole; Female; Humans; Membrane Proteins; Microcirculation; Middle Aged; Nucleoside Transport Proteins; Pia Mater; Receptors, Purinergic; Thioinosine | 1988 |
Nucleoside transport in rat cerebral-cortical synaptosomes. Evidence for two types of nucleoside transporters.
Topics: Animals; Biological Transport; Cerebral Cortex; Dilazep; Dipyridamole; Male; Nucleosides; Rats; Rats, Inbred Strains; Synaptosomes; Thioinosine; Uridine | 1988 |
Adenosine metabolism in human whole blood. Effects of nucleoside transport inhibitors and phosphate concentration.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Biological Transport; Dilazep; Dipyridamole; Humans; Phosphates; Thioinosine | 1988 |
Adenosine handling in interstitia of cremaster muscle studied by bioassay.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Biological Assay; Cricetinae; Diffusion; Dipyridamole; Extracellular Space; Kinetics; Methods; Muscles; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Thioinosine; Vasodilation | 1988 |
Species differences in sensitivity of nucleoside transport in erythrocytes and cultured cells to inhibition by nitrobenzylthioinosine, dipyridamole, dilazep and lidoflazine.
Topics: Animals; Azepines; Biological Transport; Carrier Proteins; Cells, Cultured; Dilazep; Dipyridamole; Erythrocytes; Humans; Inosine; Lidoflazine; Membrane Proteins; Nucleoside Transport Proteins; Piperazines; Species Specificity; Thioinosine; Uridine | 1988 |
Adenosine transporters in chromaffin cells: subcellular distribution and characterization.
Topics: Adrenal Medulla; Affinity Labels; Animals; Cattle; Cell Fractionation; Cell Membrane; Cells, Cultured; Chromaffin Granules; Cytosol; Dipyridamole; Kinetics; Receptors, Purinergic; Subcellular Fractions; Thioinosine | 1988 |
Pharmacological characterization of rapidly accumulated adenosine by dissociated brain cells from adult rat.
Topics: Adenosine; Adenosine Monophosphate; Animals; Binding, Competitive; Brain; Dilazep; Dipyridamole; Inosine; Kinetics; Male; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Thioinosine; Uridine | 1988 |
Role of the nucleoside transport function in the transport and salvage of purine nucleobases.
Topics: Adenine; Animals; Antimetabolites, Antineoplastic; Azaserine; Biological Transport; Cell Line; Dipyridamole; Hypoxanthine; Hypoxanthines; Mice; Nucleosides; Purines; T-Lymphocytes; Thioinosine | 1986 |
Transport and metabolism of adenosine in human erythrocytes: effect of transport inhibitors and regulation by phosphate.
Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Kinase; Biological Transport; Coformycin; Dilazep; Dipyridamole; Erythrocytes; Humans; Pentostatin; Phosphates; Phosphorylation; Thioinosine | 1986 |
Expression of a novel high-affinity purine nucleobase transport function in mutant mammalian T lymphoblasts.
Topics: Adenine; Animals; Azaserine; Biological Transport, Active; Cell Line; Dipyridamole; Guanine; Hypoxanthine; Hypoxanthines; Kinetics; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Phenotype; Purine Nucleosides; T-Lymphocytes; Thioinosine | 1986 |
Metabolism of adenosine analogues by Schistosoma mansoni and the effect of nucleoside transport inhibitors.
Topics: Adenosine; Animals; Biological Transport; Dilazep; Dipyridamole; Kinetics; Nucleosides; Schistosoma mansoni; Structure-Activity Relationship; Thioinosine; Thionucleotides; Uracil | 1987 |
Nucleoside transporter of pig erythrocytes. Kinetic properties, isolation and reaction with nitrobenzylthioinosine and dipyridamole.
Topics: Affinity Labels; Animals; Biological Transport; Carbohydrates; Carrier Proteins; Dipyridamole; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Humans; Inosine; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Photochemistry; Swine; Thioinosine; Uridine | 1987 |
Treatment of schistosomiasis by purine nucleoside analogues in combination with nucleoside transport inhibitors.
Topics: Adenosine; Animals; Biological Transport; Dilazep; Dipyridamole; Drug Therapy, Combination; Female; Mice; Purine Nucleosides; Ribonucleosides; Schistosoma mansoni; Schistosomiasis; Thioinosine; Thionucleotides; Toyocamycin; Tubercidin; Uracil | 1987 |
Inhibition of nucleoside and nucleobase transport and nitrobenzylthioinosine binding by dilazep and hexobendine.
Topics: Animals; Azepines; Benzoates; Biological Transport; Carbon Radioisotopes; Cell Line; Cricetinae; Cricetulus; Dilazep; Dipyridamole; Erythrocytes; Hexobendine; Humans; Hypoxanthine; Hypoxanthines; Inosine; Mice; Nucleosides; Rats; Thioinosine; Uridine | 1986 |
Nucleoside transporter of cerebral microvessels and choroid plexus.
Topics: Adenosine; Affinity Labels; Animals; Blood Proteins; Blood-Brain Barrier; Brain; Capillaries; Choroid Plexus; Dipyridamole; Endothelium; Female; Guanosine; Male; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Rats; Rats, Inbred Strains; Swine; Theophylline; Thioinosine; Thionucleosides | 1986 |
Nitrobenzylthioinosine-sensitive nucleoside transport system: mechanism of inhibition by dipyridamole.
Topics: Animals; Binding, Competitive; Dipyridamole; Erythrocytes; Female; Guinea Pigs; Humans; Inosine; Kinetics; Thioinosine; Uridine | 1986 |
Photoaffinity labelling of a nitrobenzylthioinosine-binding polypeptide from cultured Novikoff hepatoma cells.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Biological Transport; Cell Membrane; Cells, Cultured; Dipyridamole; Electrophoresis, Polyacrylamide Gel; Inosine; Liver Neoplasms, Experimental; Neoplasm Proteins; Rats; Thioinosine; Uridine | 1986 |
[3H]dipyridamole binding to guinea pig brain membranes: possible heterogeneity of central adenosine uptake sites.
Topics: Adenosine; Animals; Brain; Calcium Channel Blockers; Cell Membrane; Cerebral Cortex; Dipyridamole; Guinea Pigs; Kinetics; Male; Thioinosine | 1987 |
[3H]dipyridamole binding to nucleoside transporters from guinea-pig and rat lung.
Topics: Animals; Carrier Proteins; Cell Membrane; Dilazep; Dipyridamole; Guinea Pigs; Lidoflazine; Lung; Male; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Rats; Rats, Inbred Strains; Thioinosine | 1986 |
Effects of nucleoside transport inhibitors on the salvage and toxicity of adenosine and deoxyadenosine in L1210 and P388 mouse leukemia cells.
Topics: Adenosine; Animals; Biological Transport; Coformycin; Deoxyadenosines; Dipyridamole; Inosine; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Pentostatin; Thioinosine | 1985 |
Effects of adenosine uptake blockers and adenosine on evoked potentials of guinea-pig olfactory cortex.
Topics: Adenosine; Adenosine Deaminase; Animals; Diazepam; Dilazep; Dipyridamole; Evoked Potentials; Flurazepam; Guanosine; Guinea Pigs; Hexobendine; In Vitro Techniques; Limbic System; Olfactory Pathways; Thioinosine; Thionucleosides | 1986 |
Identification of the adenosine uptake sites in guinea pig brain.
Topics: Adenosine; Affinity Labels; Animals; Brain; Dipyridamole; Female; Guinea Pigs; Membranes; Molecular Weight; Photochemistry; Thioinosine | 1985 |
Nitrobenzylthioinosine-sensitive and -resistant nucleoside transport in normal and transformed rat cells.
Topics: Animals; Binding Sites; Biological Transport; Carcinoma 256, Walker; Dipyridamole; Inosine; Kidney; Liver; Liver Neoplasms, Experimental; Male; Mathematics; Nucleosides; Rats; Thioinosine; Uridine | 1985 |
Species differences in the binding of [3H]nitrobenzylthioinosine to the nucleoside transport system in mammalian central nervous system membranes: evidence for interconvertible conformations of the binding site/transporter complex.
Topics: Adenosine; Animals; Binding Sites; Biological Transport, Active; Brain; Cell Membrane; Diazepam; Dipyridamole; Dogs; Erythrocytes; Female; Guinea Pigs; Humans; Inosine; Male; Mice; Nucleosides; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Thioinosine | 1985 |
The mechanism of adenosine release from hypoxic rat liver cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Dipyridamole; Liver; Oxygen; Rats; Thioinosine | 1985 |
Role of adenosine uptake and metabolism by blood cells in the antiplatelet actions of dipyridamole, dilazep and nitrobenzylthioinosine.
Topics: Adenosine; Azepines; Blood Platelets; Dilazep; Dipyridamole; Erythrocytes; Humans; In Vitro Techniques; Inosine; Mopidamol; Platelet Aggregation; Thioinosine | 1985 |
Saturable, high affinity binding of the nucleoside transport inhibitor, nitrobenzylthioinosine, to guinea pig cardiac membranes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding Sites; Biological Transport; Dilazep; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Inosine; Membranes; Myocardium; Thioinosine | 1983 |
Demonstration of a putative adenosine receptor in rabbit aorta.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Aorta, Thoracic; Dipyridamole; Kinetics; Microsomes; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Subcellular Fractions; Thioinosine | 1982 |
Heterogeneity of nucleoside transport in mammalian cells. Two types of transport activity in L1210 and other cultured neoplastic cells.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport; Cell Line; Diffusion; Dipyridamole; Leukemia L1210; Mice; Neoplasms, Experimental; Nucleosides; Rats; Thioinosine; Uridine | 1983 |
Transport of deoxycoformycin in human erythrocytes. Measurement by adenosine deaminase titration and radioisotope assays.
Topics: Adenosine Deaminase Inhibitors; Biological Transport; Coformycin; Dipyridamole; Erythrocytes; Humans; Kinetics; Nucleoside Deaminases; Nucleosides; Pentostatin; Ribonucleosides; Thioinosine; Tritium; Uridine | 1984 |
Modulation of adenine nucleoside excretion and incorporation in adenosine deaminase deficient human lymphoma cells.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Biological Transport; Cell Division; Cell Line; Deoxyadenosines; Dipyridamole; Humans; Lymphocytes; Lymphoma; Nucleoside Deaminases; Purine-Nucleoside Phosphorylase; Thioinosine; Thionucleosides | 1984 |
Adenosine uptake sites in dog heart and brain; interaction with calcium antagonists.
Topics: Adenosine; Animals; Blood Pressure; Brain; Calcium Channel Blockers; Coronary Circulation; Dipyridamole; Dogs; Heart Rate; Inosine; Kinetics; Myocardium; Thioinosine; Vascular Resistance | 1984 |
Heterogeneity of high affinity nitrobenzylthioinosine binding sites in mammalian cortical membranes: multiple forms of central nervous system nucleoside transporters?
Topics: Animals; Binding Sites; Binding, Competitive; Biological Transport, Active; Cerebral Cortex; Dipyridamole; Dogs; Guinea Pigs; In Vitro Techniques; Inosine; Kinetics; Membranes; Mice; Nucleosides; Rabbits; Species Specificity; Thioinosine | 1984 |
Measurement of adenosine metabolism and uptake in smooth muscle and effects of adenosine transport inhibitors.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport; Cattle; Coformycin; Coronary Vessels; Dipyridamole; Dose-Response Relationship, Drug; Female; Guanosine; Guinea Pigs; In Vitro Techniques; Inosine; Intestinal Mucosa; Male; Muscle, Smooth; Pentostatin; Rabbits; Thioinosine; Thionucleosides | 1984 |
Kinetics of nitrobenzylthioinosine binding to the human erythrocyte nucleoside transporter.
Topics: Adenosine; Binding Sites; Carrier Proteins; Dipyridamole; Erythrocyte Membrane; Humans; In Vitro Techniques; Inosine; Kinetics; Models, Biological; Nucleosides; Protein Binding; Thioinosine; Uridine | 1983 |
Nucleoside transport. Photoaffinity labelling of high-affinity nitrobenzylthioinosine binding sites in rat and guinea pig lung.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Biological Transport; Cell Membrane; Dipyridamole; Guinea Pigs; Inosine; Kinetics; Lung; Male; Nucleosides; Rats; Rats, Inbred Strains; Thioinosine; Uridine | 1984 |
Identification of the nucleoside transporter in cultured mouse lymphoma cells. Photoaffinity labeling of plasma membrane-enriched fractions from nucleoside transport-competent (S49) and nucleoside transport-deficient (AE1) cells with [3H]nitrobenzylthioin
Topics: Adenosine; Affinity Labels; Animals; Binding, Competitive; Blood Proteins; Cell Line; Cell Membrane; Dipyridamole; Guanosine; Inosine; Lymphoma; Membrane Proteins; Mice; Nucleoside Transport Proteins; Thioinosine; Thionucleosides; Tritium | 1984 |
Kinetic and thermodynamic studies on nitrobenzylthioinosine binding to the nucleoside transporter of Chinese hamster ovary cells.
Topics: Animals; Carrier Proteins; Cell Line; Cricetinae; Cricetulus; Dipyridamole; Female; Inosine; Kinetics; Nucleosides; Ovary; Papaverine; Temperature; Thermodynamics; Thioinosine; Thymidine | 1983 |
Thermodynamic differences between the binding interaction of nitrobenzylthioinosine and dipyridamole with the nucleoside transport system of human erythrocytes.
Topics: Biological Transport; Dipyridamole; Erythrocytes; Humans; In Vitro Techniques; Inosine; Kinetics; Nucleosides; Temperature; Thermodynamics; Thioinosine | 1983 |
Erythrocyte nucleoside transport: asymmetrical binding of nitrobenzylthioinosine to nucleoside permeation sites.
Topics: Animals; Binding Sites; Binding, Competitive; Biological Transport; Cell Membrane Permeability; Deoxycytidine; Dipyridamole; Erythrocytes; Humans; Inosine; Kinetics; Nucleosides; Sheep; Thioinosine; Uridine | 1982 |
Is inosine the physiological energy source of pig erythrocytes?
Topics: Adenosine Deaminase; Adenosine Triphosphate; Animals; Biological Transport; Dipyridamole; Energy Metabolism; Erythrocytes; Inosine; Kinetics; Swine; Thioinosine | 1980 |
A common basis for inhibition of nucleoside transport by dipyridamole and nitrobenzylthioinosine?
Topics: Binding, Competitive; Dipyridamole; HeLa Cells; Humans; Inosine; Lidoflazine; Nucleosides; Thioinosine; Uridine | 1980 |
Time-dependent antinociceptive interactions between opioids and nucleoside transport inhibitors.
Topics: Adenosine; Analgesics; Animals; Biological Transport; Dilazep; Dipyridamole; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Narcotics; Nucleosides; Receptors, Opioid; Thioinosine; Time Factors | 1995 |
Increased acetylcholine content induced by antidromic stimulation of a sympathetic ganglion: a possible retrograde action of adenosine.
Topics: Acetylcholine; Adenosine; Animals; Calcium; Carrier Proteins; Cats; Culture Media; Dipyridamole; Electric Stimulation; Female; Ganglia, Sympathetic; Male; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine | 1995 |
Toxoplasma gondii tachyzoites possess an unusual plasma membrane adenosine transporter.
Topics: Adenosine; Adenosine Kinase; Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Dipyridamole; Membrane Proteins; Nucleoside Transport Proteins; Protozoan Proteins; Purines; Thioinosine; Toxoplasma | 1995 |
Nucleoside transport and metabolism in lymphocytes, polymorphonuclear cells and cerebral synaptosomes.
Topics: Adenosine; Animals; Biological Transport; Cerebral Cortex; Child; Deoxycytidine; Dilazep; Dipyridamole; DNA; Humans; Kinetics; Lymphocytes; Neutrophils; Nucleosides; Palatine Tonsil; Papaverine; Rats; Synaptosomes; Thioinosine; Thymidine; Uridine | 1994 |
Inhibition of nucleoside transport by reactive oxygen species in bovine heart microvascular endothelial cells.
Topics: Adenosine; Animals; Biological Transport; Cattle; Cell Line; Dipyridamole; Endothelium, Vascular; Heart; Hydrogen Peroxide; Hypochlorous Acid; Inosine; Kinetics; Nucleosides; Reactive Oxygen Species; Thioinosine; Uridine; Vitamin K | 1994 |
Involvement of bidirectional adenosine transporters in the release of L-[3H]adenosine from rat brain synaptosomal preparations.
Topics: Adenosine; Animals; Biological Transport; Brain; Carrier Proteins; Dilazep; Dipyridamole; Kinetics; Male; Membrane Proteins; Nucleoside Transport Proteins; Potassium Chloride; Rats; Rats, Sprague-Dawley; Synaptosomes; Thioinosine; Tritium | 1995 |
Endogenous adenosine exerts inhibitory effects upon the development of spreading depression and glutamate release induced by microdialysis with high K+ in rat hippocampus.
Topics: Adenosine; Animals; Cortical Spreading Depression; Dipyridamole; Glutamic Acid; Hippocampus; Male; Microdialysis; Potassium; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Theophylline; Thioinosine; Xanthines | 1994 |
Homologous desensitization of the A1-adenosine receptor system in the guinea pig atrioventricular node.
Topics: Adenosine; Adenosine Diphosphate Ribose; Animals; Atrioventricular Node; Binding Sites; Biological Transport; Carbachol; Cell Membrane; Dipyridamole; Down-Regulation; Female; Gallopamil; GTP-Binding Proteins; Guinea Pigs; Magnesium Chloride; Male; Myocardium; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Thioinosine; Time Factors; Virulence Factors, Bordetella | 1995 |
Evidence that adenine nucleotides modulate nucleoside-transporter function. Characterization of uridine transport in chromaffin cells and plasma membrane vesicles.
Topics: Adenine Nucleotides; Adrenal Medulla; Affinity Labels; Animals; Biological Transport; Carrier Proteins; Cattle; Cell Membrane; Cells, Cultured; Dipyridamole; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Uridine | 1994 |
Effect of dipyridamole on glomerular mesangial cell ecto-5'-nucleotidase expression.
Topics: 5'-Nucleotidase; Adenosine; Affinity Labels; Animals; Cycloheximide; Dactinomycin; Dipyridamole; Glomerular Mesangium; Rats; Rats, Sprague-Dawley; Thioinosine | 1994 |
(3H)dipyridamole and (3H)nitrobenzylthioinosine binding sites at the human parietal cortex and erythrocyte adenosine transporter: a comparison.
Topics: Adenosine; Binding Sites; Binding, Competitive; Biological Transport; Dipyridamole; Erythrocytes; Humans; Parietal Lobe; Thioinosine | 1994 |
Decrease in equilibrative uridine transport during monocytic differentiation of HL-60 leukaemia: involvement of protein kinase C.
Topics: Affinity Labels; Alkaloids; Binding Sites; Biological Transport; Cell Differentiation; Dilazep; Dipyridamole; Humans; Kinetics; Leukemia; Monocytes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thioinosine; Thymidine; Tumor Cells, Cultured; Uracil; Uridine | 1994 |
Studies of the nucleoside transporter inhibitor, draflazine, in the human myocardium.
Topics: Adult; Affinity Labels; Aged; Carbachol; Cardiac Pacing, Artificial; Carrier Proteins; Dipyridamole; Erythrocyte Membrane; Female; Heart; Humans; In Vitro Techniques; Male; Membrane Proteins; Middle Aged; Myocardial Contraction; Myocardium; Nucleoside Transport Proteins; Phenylisopropyladenosine; Piperazines; Radioligand Assay; Thioinosine | 1994 |
The enhancement of the frequency of resistance to N-phosphonoacetyl-L-aspartate and methotrexate by 1-beta-D-arabinofuranosylcytosine: the effect of dipyridamole.
Topics: Animals; Aspartic Acid; Cell Line, Transformed; Cricetinae; Cytarabine; Dipyridamole; Drug Resistance; Drug Synergism; Humans; Methotrexate; Nucleosides; Phosphonoacetic Acid; Thioinosine | 1994 |
Enhancement of proliferation in cultures of Chinook salmon embryo cells by interactions between inosine and bovine sera.
Topics: Animals; Biological Transport; Cattle; Cell Division; Cell Line; Dipyridamole; Fetal Blood; Inosine; Nucleosides; Purines; Pyrimidines; Salmon; Thioinosine; Thymidine; Time Factors | 1994 |
High expression of nitrobenzylthioinosine-insensitive dipyridamole binding sites in postmortem human ependymal tissue.
Topics: Adult; Affinity Labels; Aged; Aged, 80 and over; Binding Sites; Dipyridamole; Ependyma; Female; Humans; Male; Middle Aged; Regression Analysis; Thioinosine | 1994 |
Facilitatory and inhibitory modulation by endogenous adenosine of noradrenaline release in the epididymal portion of rat vas deferens.
Topics: Adenosine; Adenosine Deaminase; Animals; Dipyridamole; Electric Stimulation; Epididymis; In Vitro Techniques; Lactates; Male; Muscle, Smooth; Norepinephrine; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Thioinosine; Vas Deferens | 1993 |
Morphine-evoked release of adenosine from the spinal cord occurs via a nucleoside carrier with differential sensitivity to dipyridamole and nitrobenzylthioinosine.
Topics: Adenosine; Animals; Capsaicin; Dipyridamole; In Vitro Techniques; Male; Morphine; Norepinephrine; Nucleosides; Potassium; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Synaptosomes; Thioinosine | 1993 |
High affinity sodium-dependent nucleobase transport in cultured renal epithelial cells (LLC-PK1).
Topics: Animals; Biological Transport; Cations, Monovalent; Cell Line; Dilazep; Dipyridamole; Epithelium; Hypoxanthine; Hypoxanthines; Kidney; Kinetics; Nucleosides; Purines; Pyrimidines; Sodium; Thioinosine; Tritium | 1993 |
Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells.
Topics: Adenosine; Amino Acid Sequence; Animals; Base Sequence; Biological Transport; Carrier Proteins; Cells, Cultured; Dilazep; Dipyridamole; Genes, myc; Guanosine; Haplorhini; Intestines; Kidney; Membrane Transport Proteins; Molecular Sequence Data; Nucleosides; Pyrimidine Nucleosides; Rats; Recombinant Proteins; Thioinosine; Transfection; Uridine | 1996 |
Characterization of inhibitor-sensitive and -resistant adenosine transporters in cultured human fetal astrocytes.
Topics: Adenine; Adenosine; Affinity Labels; Astrocytes; Biological Transport; Carrier Proteins; Cells, Cultured; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetus; Humans; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Tritium; Tubercidin; Vasodilator Agents | 1996 |
Adenosine transport inhibitors enhance high K(+)-evoked taurine release from rat hippocampus.
Topics: Adenosine; Animals; Biological Transport; Calcium; Cortical Spreading Depression; Dipyridamole; Glutamic Acid; Hippocampus; Male; Microdialysis; Potassium; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Taurine; Theophylline; Thioinosine | 1996 |
[3H]adenosine transport in DDT1 MF-2 smooth muscle cells: inhibition by metabolites of propentofylline.
Topics: Adenosine; Animals; Binding Sites; Biological Transport; Cricetinae; Dilazep; Dipyridamole; Genital Neoplasms, Male; Kinetics; Leiomyosarcoma; Leukemia L1210; Male; Mesocricetus; Muscle, Smooth; Rats; Thioinosine; Tumor Cells, Cultured; Vas Deferens; Xanthines | 1996 |
Chronic dipyridamole administration downregulates [3H]nitrobenzylthioinosine binding site affinity in guinea pig kidney but not heart and brain.
Topics: Animals; Binding Sites; Brain; Dipyridamole; Guinea Pigs; Kidney; Male; Myocardium; Radioligand Assay; Rats; Rats, Sprague-Dawley; Thioinosine; Tritium | 1996 |
Comparison of nucleoside transport binding sites in rabbit iris-ciliary body and cultured rabbit nonpigmented ciliary epithelial cells.
Topics: Adenosine; Affinity Labels; Animals; Binding Sites; Binding, Competitive; Blood Proteins; Carrier Proteins; Cells, Cultured; Ciliary Body; Dipyridamole; Epithelium; Female; Iris; Male; Membrane Proteins; Nucleoside Transport Proteins; Pigment Epithelium of Eye; Rabbits; Thioinosine | 1996 |
Endogenous adenosine inhibits evoked substance P release from perifused networks of myenteric ganglia.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphatases; Animals; Biological Transport; Dipyridamole; Ganglia; Guinea Pigs; Ileum; In Vitro Techniques; Myenteric Plexus; Nerve Net; Radioimmunoassay; Receptors, Purinergic P1; Substance P; Tetrodotoxin; Thioinosine; Xanthines | 1997 |
Plasticity of cardiovascular nucleoside transporters following chronic dipyridamole treatment.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport; Brain; Cardiovascular System; Cell Membrane; Dipyridamole; Guinea Pigs; Kidney; Male; Myocardium; Nucleosides; Rats; Receptors, Purinergic P1; Thioinosine | 1997 |
Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Carrier Proteins; Cloning, Molecular; Dilazep; Dipyridamole; Electrophoresis, Polyacrylamide Gel; Equilibrative Nucleoside Transport Proteins; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Humans; Membrane Proteins; Molecular Sequence Data; Nuclear Proteins; Nucleoside Transport Proteins; Peptide Mapping; Protein Structure, Secondary; Rats; Sequence Alignment; Thioinosine; Vasodilator Agents; Xenopus | 1997 |
Effects of nucleoside transport inhibitors and adenine/ribose supply on ATP concentration and adenosine production in cardiac myocytes.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Biological Transport; Carrier Proteins; Dipyridamole; Enzyme Inhibitors; Membrane Proteins; Myocardium; NAD; Nucleoside Transport Proteins; Rats; Rats, Sprague-Dawley; Ribose; Thioinosine | 1998 |
Effects of nucleoside transport inhibitors and adenine/ribose on ATP concentration and adenosine production in cardiac myocytes.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Biological Transport; Cells, Cultured; Dipyridamole; Heart; Myocardium; Rats; Rats, Sprague-Dawley; Thioinosine | 1998 |
Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Binding Sites; Cardiovascular Agents; Carrier Proteins; Dipyridamole; Equilibrative Nucleoside Transport Proteins; Equilibrative Nucleoside Transporter 1; Humans; Membrane Proteins; Molecular Sequence Data; Oocytes; Protein Conformation; Protein Structure, Secondary; Rats; Recombinant Fusion Proteins; Thioinosine; Vasodilator Agents; Xenopus | 1998 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyridamole; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Nucleus Accumbens; Phosphodiesterase Inhibitors; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Thioinosine; Vasodilator Agents; Xanthines | 1998 |
Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Cell Division; Cell Survival; Deoxycytidine; Dipyridamole; DNA, Complementary; Gemcitabine; HeLa Cells; Humans; K562 Cells; Kinetics; Membrane Proteins; Membrane Transport Proteins; Nucleoside Transport Proteins; Recombinant Proteins; Thioinosine; Transfection; Tumor Cells, Cultured | 1998 |
Cloning of the Candida albicans nucleoside transporter by complementation of nucleoside transport-deficient Saccharomyces.
Topics: Adenosine; Amino Acid Sequence; Base Sequence; Candida albicans; Carrier Proteins; Cloning, Molecular; Dipyridamole; Genetic Complementation Test; Guanosine; Membrane Proteins; Molecular Sequence Data; Nucleoside Transport Proteins; Purine Nucleosides; Saccharomyces cerevisiae; Substrate Specificity; Thioinosine; Uridine | 1998 |
Sensitization by chronic diazepam treatment of A2A adenosine receptor-mediated relaxation in rat pulmonary artery.
Topics: Adenosine; Animals; Carrier Proteins; Diazepam; Dinucleoside Phosphates; Dipyridamole; Dose-Response Relationship, Drug; Female; Heart; Heart Atria; Muscle Relaxation; Phenethylamines; Pulmonary Artery; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Thioinosine; Triazines; Triazoles; Verapamil | 1999 |
Functional production and reconstitution of the human equilibrative nucleoside transporter (hENT1) in Saccharomyces cerevisiae. Interaction of inhibitors of nucleoside transport with recombinant hENT1 and a glycosylation-defective derivative (hENT1/N48Q).
Topics: Base Sequence; Biological Transport; Carrier Proteins; Dilazep; Dipyridamole; DNA Primers; Equilibrative Nucleoside Transporter 1; Genetic Complementation Test; Glycosylation; Humans; Kinetics; Membrane Proteins; Proteolipids; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Thioinosine; Thymidine | 1999 |
Quantification of extracellular and intracellular adenosine production: understanding the transmembranous concentration gradient.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Biological Transport; Bradykinin; Coronary Circulation; Cytosol; Depression, Chemical; Dipyridamole; Drug Synergism; Enzyme Inhibitors; Extracellular Space; Guinea Pigs; Heart; Models, Biological; Myocardium; Osmolar Concentration; Oxygen; Oxygen Consumption; Piperazines; Thioinosine; Tubercidin | 1999 |
Regulation of extracellular adenosine in rat hippocampal slices is temperature dependent: role of adenosine transporters.
Topics: Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Animals; Carrier Proteins; Dipyridamole; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Excitatory Postsynaptic Potentials; Extracellular Space; Hippocampus; In Vitro Techniques; Male; Membrane Proteins; Rats; Rats, Sprague-Dawley; Temperature; Thioinosine | 2000 |
Bryostatin 1-induced modulation of nucleoside transporters and 2-chlorodeoxyadenosine influx in WSU-CLL cells.
Topics: Aged; Antineoplastic Agents; Biological Transport, Active; Bryostatins; Carrier Proteins; Cladribine; Deoxycytidine Kinase; Dipyridamole; Down-Regulation; Drug Resistance, Neoplasm; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Male; Membrane Proteins; Nucleoside Transport Proteins; Phosphorylation; Thioinosine; Tumor Cells, Cultured; Vidarabine | 2000 |
Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for i
Topics: Biological Transport; Carrier Proteins; Cell Line; Cytidine; Dipyridamole; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Genetic Complementation Test; Guanosine; Humans; Inosine; Kinetics; Membrane Proteins; Nucleosides; Thioinosine | 2000 |
Further characterization of an adenosine transport system in the mitochondrial fraction of rat testis.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzodiazepinones; Biological Transport; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Guanosine; Hexobendine; Hydrogen-Ion Concentration; Inosine; Isoquinolines; Kinetics; Male; Mitochondria; Osmolar Concentration; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Sodium; Subcellular Fractions; Temperature; Testis; Thioinosine; Thionucleosides; Time Factors; Tritium; Uridine | 2000 |
Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy.
Topics: Adenine; Amino Acid Sequence; Animals; Antimalarials; Biological Transport; Blotting, Southern; Carrier Proteins; Cations; Cell Membrane; Cloning, Molecular; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Nucleobase, Nucleoside, Nucleotide, and Nucleic Acid Transport Proteins; Nucleosides; Phylogeny; Piperazines; Plasmodium falciparum; Platelet Aggregation Inhibitors; Protein Structure, Secondary; Protozoan Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Thioinosine; Time Factors; Uridine; Vasodilator Agents; Xenopus | 2000 |
Selective transport of adenosine into porcine coronary smooth muscle.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Biological Transport; Carrier Proteins; Coronary Vessels; Dinoprost; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; In Vitro Techniques; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Substrate Specificity; Swine; Thioinosine; Vasoconstriction; Vasodilation; Vasodilator Agents | 2000 |
Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).
Topics: Amino Acid Sequence; Animals; Biological Transport; Carrier Proteins; Cell Differentiation; Dilazep; Dipyridamole; Electric Conductivity; Evolution, Molecular; HL-60 Cells; Humans; Membrane Transport Proteins; Mice; Models, Molecular; Molecular Sequence Data; Purine Nucleosides; Pyrimidine Nucleosides; Recombinant Proteins; Sequence Homology, Amino Acid; Sodium; Substrate Specificity; Symporters; Thioinosine; Uridine | 2001 |
Cloning of a novel isoform of the mouse NBMPR-sensitive equilibrative nucleoside transporter (ENT1) lacking a putative phosphorylation site.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Casein Kinase II; Cloning, Molecular; Dipyridamole; Equilibrative Nucleoside Transporter 1; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Leukemia, T-Cell; Membrane Proteins; Mice; Molecular Sequence Data; Nucleoside Transport Proteins; Phosphorylation; Protein Isoforms; Protein Serine-Threonine Kinases; Rats; Sequence Homology, Amino Acid; Thioinosine; Tumor Cells, Cultured | 2001 |
Hypoxanthine transport in human tumour cell lines: relationship to the inhibition of hypoxanthine rescue by dipyridamole.
Topics: Affinity Labels; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Division; Chromatography, High Pressure Liquid; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Equilibrative Nucleoside Transport Proteins; Folic Acid Antagonists; Humans; Hypoxanthine; Kinetics; Phosphodiesterase Inhibitors; Sodium; Thioinosine; Thymidine; Tumor Cells, Cultured | 2001 |
Mutation of residue 33 of human equilibrative nucleoside transporters 1 and 2 alters sensitivity to inhibition of transport by dilazep and dipyridamole.
Topics: Amino Acid Sequence; Animals; Biological Transport; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Humans; Membrane Transport Proteins; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Recombinant Proteins; Structure-Activity Relationship; Thioinosine; Uridine; Xenopus laevis | 2002 |
Nucleoside transport inhibitors, dipyridamole and p-nitrobenzylthioinosine, selectively potentiate the antitumor activity of NB1011.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bromodeoxyuridine; Carrier Proteins; Cell Survival; Colonic Neoplasms; Dipyridamole; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Membrane Proteins; Nucleoside Transport Proteins; Quinazolines; Thioinosine; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 2002 |
Extracellular purines from cells of seminiferous tubules.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Cells, Cultured; Dipyridamole; Enzyme Inhibitors; Extracellular Space; Germ Cells; Kinetics; Male; Paracrine Communication; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Wistar; Receptors, Purinergic; Seminiferous Tubules; Sertoli Cells; Thioinosine | 2003 |
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro.
Topics: Action Potentials; Adenosine; Affinity Labels; Animals; Colforsin; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Enkephalins; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Isoquinolines; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Neural Inhibition; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Probenecid; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Substance Withdrawal Syndrome; Sulfonamides; Synaptic Transmission; Thioinosine; Time Factors; Uricosuric Agents; Vasodilator Agents; Xanthines | 2003 |
Uptake of nitrobenzylthioinosine and purine beta-L-nucleosides by intracellular Toxoplasma gondii.
Topics: Animals; Biological Transport; Cells, Cultured; Dipyridamole; Fibroblasts; Humans; Hypoxanthine; Mice; Mice, Inbred Strains; Nucleoside Transport Proteins; Purine Nucleosides; Stereoisomerism; Thioinosine; Toxoplasma | 2003 |
Inhibition of glucose uptake in murine cardiomyocyte cell line HL-1 by cardioprotective drugs dilazep and dipyridamole.
Topics: Adenosine; Animals; Biological Transport; Cardiotonic Agents; Cell Line; Deoxyglucose; Dilazep; Dipyridamole; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Kinetics; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Myocytes, Cardiac; Thioinosine | 2004 |
Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.
Topics: Adenosine; Amino Acid Substitution; Biological Transport; Dilazep; Dipyridamole; Drug Resistance; Equilibrative Nucleoside Transporter 1; Guanosine; Humans; Inhibitory Concentration 50; Inosine; Leucine; Mutagenesis; Mutation, Missense; Point Mutation; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Thioinosine | 2004 |
Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep.
Topics: Biological Transport; Dilazep; Dipyridamole; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Glycine; Humans; Nucleosides; Thioinosine; Vasodilator Agents | 2004 |
Extracellular inosine is modulated by H2O2 and protects sertoli cells against lipoperoxidation and cellular injury.
Topics: Adenine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Inosine; Lipid Peroxidation; Male; Niacinamide; Oxidants; Oxidative Stress; Rats; Sertoli Cells; Thioinosine | 2004 |
Pharmacological analysis and molecular cloning of the canine equilibrative nucleoside transporter 1.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Carrier Proteins; Cell Line; Cloning, Molecular; Dilazep; Dipyridamole; DNA, Complementary; Dogs; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transporter 1; Formycins; Kinetics; Molecular Sequence Data; Piperazines; Protein Binding; Protein Conformation; Radioligand Assay; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Structure-Activity Relationship; Thioinosine; Tritium | 2004 |
Hypoxia induces adenosine release from the rat carotid body.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Carotid Body; Carrier Proteins; Chemoreceptor Cells; Dipyridamole; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Membrane Transport Proteins; Nucleoside Transport Proteins; Rats; Rats, Wistar; Thioinosine | 2004 |
Nucleoside transporter subtype expression and function in rat skeletal muscle microvascular endothelial cells.
Topics: Animals; Capillaries; Cell Separation; Cells, Cultured; Dilazep; Dipyridamole; DNA Primers; Endothelial Cells; Formycins; Muscle, Skeletal; Nucleoside Transport Proteins; Piperazines; Radioligand Assay; Rats; Reverse Transcriptase Polymerase Chain Reaction; Thioinosine; Vasodilator Agents | 2004 |
CPEC induces erythroid differentiation of human myeloid leukemia K562 cells through CTP depletion and p38 MAP kinase.
Topics: Affinity Labels; Carbon-Nitrogen Ligases; Cell Differentiation; Cytidine; Cytidine Triphosphate; Dipyridamole; Enzyme Inhibitors; Equilibrative Nucleoside Transporter 1; Erythroid Precursor Cells; Humans; Isoxazoles; K562 Cells; Leflunomide; Leukemia, Myeloid; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase Inhibitors; Pyrimidines; RNA, Small Interfering; S Phase; Thioinosine | 2004 |
Residues Met89 and Ser160 in the human equilibrative nucleoside transporter 1 affect its affinity for adenosine, guanosine, S6-(4-nitrobenzyl)-mercaptopurine riboside, and dipyridamole.
Topics: Adenosine; Amino Acid Sequence; Biological Transport; Dipyridamole; Equilibrative Nucleoside Transporter 1; Genetic Complementation Test; Guanosine; Humans; Kinetics; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Thioinosine | 2005 |
Astrocytes and neurons: different roles in regulating adenosine levels.
Topics: Adenosine; Affinity Labels; Animals; Astrocytes; Brain Ischemia; Cells, Cultured; Deoxyglucose; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Hypoxia; Inosine; Models, Biological; Neurons; Oligomycins; Phosphodiesterase Inhibitors; Prosencephalon; Purines; Rats; Thioinosine; Tritium | 2005 |
In-vitro and in-vivo anti-cancer activity of a novel gemcitabine-cardiolipin conjugate.
Topics: Animals; Antineoplastic Agents; Body Weight; Cardiolipins; Cell Proliferation; Deoxycytidine; Dipyridamole; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Gemcitabine; HT29 Cells; Humans; Leukemia P388; Leukocyte Count; Mice; Mice, SCID; Neutropenia; Nucleoside Transport Proteins; Pancreatic Neoplasms; Thioinosine; Xenograft Model Antitumor Assays | 2006 |
Effect of nucleoside transport blockade on the interstitial adenosine level characterized by a novel method in guinea pig atria.
Topics: Adenosine; Animals; Biological Transport; Dipyridamole; Extracellular Fluid; Guinea Pigs; Heart Atria; Male; Myocardial Contraction; Nucleosides; Thioinosine | 2006 |
Characterization of resistance to cytosine arabinoside (Ara-C) in NALM-6 human B leukemia cells.
Topics: Cell Line, Tumor; Cell Survival; Cytarabine; Cytidine Deaminase; Cytoprotection; Deoxycytidine Kinase; Dipyridamole; Drug Resistance, Neoplasm; Gene Expression; Humans; Leukemia; RNA, Messenger; Thioinosine | 2007 |
Adenosine uptake-dependent C6 cell growth inhibition.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Adenosine Deaminase; Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Animals; Brain Neoplasms; Cell Count; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Dipyridamole; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Glioma; Hydrolysis; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Thioinosine; Uridine | 2007 |
Nucleoside and nucleobase transporters of primary human cardiac microvascular endothelial cells: characterization of a novel nucleobase transporter.
Topics: 2-Chloroadenosine; Animals; Cell Culture Techniques; Cell Line; Cells, Cultured; Child, Preschool; Coronary Vessels; Dilazep; Dipyridamole; Dogs; Endothelial Cells; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Female; Humans; Hypoxanthine; Kinetics; Microcirculation; Nucleobase Transport Proteins; Piperazines; Protein Binding; Purines; Rats; Swine; Thioinosine; Transfection; Tritium | 2007 |
Cytotoxic activities of nucleoside and nucleobase analog drugs in malignant mesothelioma: characterization of a novel nucleobase transport activity.
Topics: Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Cell Survival; Dipyridamole; Drug Synergism; Equilibrative Nucleoside Transporter 1; Humans; Mesothelioma; Nucleosides; Papaverine; Purines; Pyrimidines; Thioinosine | 2008 |
Mutation of Trp29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity.
Topics: Adenosine; Biological Transport; Dilazep; Dipyridamole; Enzyme Activation; Equilibrative Nucleoside Transporter 1; Humans; Kinetics; Models, Biological; Mutation; Nucleosides; Piperazines; Protein Binding; Thioinosine; Tryptophan; Vasodilator Agents | 2008 |
Prevention of early loss of transplanted islets in the liver of mice by adenosine.
Topics: Adenosine; Animals; Antibodies; Blood Glucose; CD11b Antigen; CD4 Antigens; Diabetes Mellitus, Experimental; Dipyridamole; Dose-Response Relationship, Drug; Galactosylceramides; Graft Rejection; Graft Survival; Immunosuppressive Agents; Injections, Intraperitoneal; Interferon-gamma; Islets of Langerhans Transplantation; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Natural Killer T-Cells; Neutrophils; Nucleoside Transport Proteins; Receptors, Chemokine; Thioinosine; Time Factors; Transplantation Tolerance; Transplantation, Homologous | 2009 |
Comparison of uptake mechanisms for anthracyclines in human leukemic cells.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Dipyridamole; HL-60 Cells; Humans; Leukemia; MCF-7 Cells; Nucleoside Transport Proteins; Nucleosides; Purinergic Antagonists; Suramin; Temperature; Thioinosine; Verapamil | 2013 |
Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine Diphosphate; Animals; Benzyl Compounds; Convulsants; Dipyridamole; Gene Expression Regulation; Genes, fos; Pentylenetetrazole; Phenethylamines; Phosphodiesterase Inhibitors; Seizures; Signal Transduction; Thioinosine; Xanthines; Zebrafish | 2015 |
Vector-independent transmembrane transport of oligodeoxyribonucleotides involves p38 mitogen activated protein kinase phosphorylation.
Topics: Adolescent; Adult; Aged; Biological Transport; Child; Child, Preschool; Cytoplasm; Dipyridamole; Female; Humans; Infant; K562 Cells; Leukemia; Male; Middle Aged; Oligodeoxyribonucleotides; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Thioinosine | 2017 |