Compounds > dipyridamole

dipyridamole and simvastatin

dipyridamole has been researched along with simvastatin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's3 (25.00)29.6817
2010's8 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baller, D; Betker, S; Gleichmann, U; Holzinger, J; Lehmann, J; Montanus, H; Notohamiprodjo, G; Weise, R1
Hwang, SK; Kim, HH; Lee, HS; Liao, JK; Moskowitz, MA; Sawada, N; Soydan, G; Waeber, C; Zhou, Z1
Birnbaum, Y; Long, B; Perez-Polo, JR; Qian, J; Ye, Y1
Birnbaum, Y; Perez-Polo, JR; Ye, Y1
Cohn, S; Deller, R; Edwards, D; Fletcher, K; Giles, M; Hobbs, V; Lasserson, D; Mant, J; McGuire, G; McManus, R; Norrie, J; Sims, D; Weir, C; Whittle, F1

Reviews

2 review(s) available for dipyridamole and simvastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Protecting against ischemia-reperfusion injury: antiplatelet drugs, statins, and their potential interactions.
    Annals of the New York Academy of Sciences, 2010, Volume: 1207

    Topics: Aspirin; Cilostazol; Dipyridamole; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Models, Cardiovascular; Myocardial Infarction; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Simvastatin; Tetrazoles

2010

Trials

1 trial(s) available for dipyridamole and simvastatin

ArticleYear
RApid Primary care Initiation of Drug treatment for Transient Ischaemic Attack (RAPID-TIA): study protocol for a pilot randomised controlled trial.
    Trials, 2013, Jul-02, Volume: 14

    Topics: Antihypertensive Agents; Aspirin; Cardiovascular Agents; Clinical Protocols; Dipyridamole; Drug Administration Schedule; Drug Therapy, Combination; Emergency Service, Hospital; England; Feasibility Studies; General Practice; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Attack, Transient; Pilot Projects; Primary Health Care; Referral and Consultation; Research Design; Secondary Prevention; Simvastatin; Time Factors; Treatment Outcome

2013

Other Studies

9 other study(ies) available for dipyridamole and simvastatin

ArticleYear
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Improved coronary vasodilator capacity by drug lipid lowering therapy in patients in the early stage of coronary atherosclerosis with reduced coronary reserves and moderate LDL hypercholesteremia].
    Zeitschrift fur Kardiologie, 1998, Volume: 87 Suppl 2

    Topics: Adult; Aged; Cholesterol, LDL; Combined Modality Therapy; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Diet, Fat-Restricted; Dipyridamole; Exercise Test; Female; Follow-Up Studies; Humans; Hypercholesterolemia; Hypolipidemic Agents; Male; Middle Aged; Simvastatin; Treatment Outcome; Vasodilation

1998
Additive effects of statin and dipyridamole on cerebral blood flow and stroke protection.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008, Volume: 28, Issue:7

    Topics: Animals; Cerebrovascular Circulation; Dipyridamole; Drug Synergism; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Regional Blood Flow; Simvastatin; Stroke; Up-Regulation

2008
Dipyridamole with low-dose aspirin augments the infarct size-limiting effects of simvastatin.
    Cardiovascular drugs and therapy, 2010, Volume: 24, Issue:5-6

    Topics: Animals; Aspirin; CREB-Binding Protein; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Simvastatin

2010