dipyridamole and methotrexate

dipyridamole has been researched along with methotrexate in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (34.55)	18.7374
1990's	13 (23.64)	18.2507
2000's	13 (23.64)	29.6817
2010's	10 (18.18)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Bindels, RJM; Peters, JGP; Russel, FGM; Smeets, PHE; van Aubel, RAMH	1
Hummel-Eisenbeiss, J; Jedlitschky, G; Keppler, D; Nies, AT; Rius, M	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bankala, R; Doss, HM; Kapavarapu, RK; Kulkarni, P; Kumar, JS; Mathew, JE; Medishetti, R; Mudgal, J; Pal, M; Parsa, KVL; Ramarao, EVVS; Rasool, M; Shenoy, GG; Sunke, R; Thirupataiah, B	1
Marz, R; Plagemann, PG; Wohlhueter, RM	1
Grem, JL	1
Taniki, T; Weber, G; Zhen, YS	1
Harstrick, A; Köhne-Wömpner, CH; Poliwoda, H; Schmoll, HJ; Schöber, C; Wilke, H	1
Chan, TC; Howell, SB	1
Donaldson, JT; Keane, TE; Norwood, DL; Poulton, SH; Rosner, G; Walther, PJ	1
Clarke, R; Kennedy, DG; Murphy, RF; Van den Berg, HW	1
Milstone, LM; Schwartz, PM	1
Goel, R; Howell, SB; Kirmani, S	1
Lönn, S; Lönn, U; Nylen, U; Winblad, G	1
Cao, SS	1
Bennett, A; Chambers, EA; Gaffen, JD	1
Goel, R; Howell, SB; Sanga, R	1
Higano, CS; Livingston, RB	1
Cao, SS; Zhen, YS	1
Balis, FM; Cleary, SM; Goel, R; Horton, C; Howell, SB; Kirmani, S; Zimm, S	1
Alberti, D; Bruggink, J; Fischer, PH; Grem, JL; Nieting, L; Remick, SC; Trump, DL; Tutsch, KD; Willson, JK	1
Hughes, JM; Tattersall, MH	1
Fischer, PH; Pangallo, CA; Van Mouwerik, TJ; Willson, JK	1
Green, MD; Muggia, FM; Subar, M; Wadler, S; Wiernik, PH	1
Mroczka, D; Nelson, JA	1
Plagemann, PG; Wohlhueter, RM	1
Drake, S; Nelson, JA	1
Bover, L; Cabral, S; Leis, S; Mordoh, J; Nembrot, M	1
Bermúdez, J; Roig, T	1
Goz, B; Jeffs, L	1
Alcaraz, JE; Heath, DD; Howell, SB; Jekunen, AP; Shalinsky, DR	1
Hirose, M; Kuroda, Y; Takeda, E	1
Bamberger, U; Boven, E; Feller, N; Jansen, WJ; Pinedo, HM; van der Wilt, CL	1
Anderson, M; Chu, E; Dearing, MP; Englee-Miller, MJ; Gazdar, AF; Kramer, BS; Kratzke, RA; Mulshine, JL; Venzon, D; Weinstein, J	1
Köhne, CH; Schmoll, HJ; Schöffski, P; Wilke, H	1
Büchele, T; Dempke, W; Grothey, A; Schmoll, HJ	1
McIvor, RS; Sweeney, CL; Warlick, CA	1
Dzhandzhugazyan, KN; Guldberg, P; Kirkin, AF; Worm, J	1
Cole, PD; Kamen, BA; Smith, AK	1
Barrera, P; Riksen, NP; Rongen, GA; Smits, P; van den Broek, PH; van Riel, PL	1
Corzo, C; de Anta, JM; Espinet, B; Mayo, C; Mayol, X; Petzold, M; Real, FX; Salido, M; Serrano, S; Solé, F; Villa, O	1
Ahishali, E; Akyuz, F; Badur, S; Demir, K; Gurel Polat, N; Ibrisim, D; Kaymakoglu, S; Mungan, Z; Poturoglu, S	1
Bartier, WA; Chong, L; Ma, G; Tattersall, MH	1
Hyland, KA; McIvor, RS; Olson, ER	1

Reviews

5 review(s) available for dipyridamole and methotrexate

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Biochemical modulation of fluorouracil by dipyridamole: preclinical and clinical experience. Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 3 Topics: Colonic Neoplasms; Deoxyuridine; Dipyridamole; DNA Damage; DNA, Neoplasm; Drug Interactions; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Nucleosides; Nucleotides; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine Monophosphate	1992
Modulation of cytotoxic drug activity by dipyridamole. Cancer treatment reviews, 1990, Volume: 17 Suppl A Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Cytarabine; Dipyridamole; Drug Interactions; Etoposide; Fluorouracil; Humans; Leucovorin; Methotrexate	1990
The dead end of 5-fluorouracil double modulation and promise of continuous infusion schedules in the treatment of metastatic colorectal cancer. The Journal of infusional chemotherapy, 1996,Fall, Volume: 6, Issue:4 Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Clinical Trials, Phase II as Topic; Colorectal Neoplasms; Combined Modality Therapy; Dipyridamole; Drug Administration Schedule; Drug Synergism; Enzyme Inhibitors; Female; Fluorouracil; Humans; Immunologic Factors; Infusions, Intravenous; Injections, Intravenous; Interferons; Leucovorin; Liver Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Neoplasm Proteins; Nucleotides; Palliative Care; Phosphonoacetic Acid; Randomized Controlled Trials as Topic; Thymidylate Synthase	1996
Where do we stand with 5-fluorouracil? Seminars in oncology, 1999, Volume: 26, Issue:6 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Chronotherapy; Colorectal Neoplasms; Dipyridamole; Drug Synergism; Fluorouracil; Humans; Interferons; Leucovorin; Levamisole; Methotrexate; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Trimetrexate; Zidovudine	1999

Trials

1 trial(s) available for dipyridamole and methotrexate

Article	Year
Oral dipyridamole and methotrexate in human solid tumors: a toxicity trial. Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:4 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Humans; Injections, Intramuscular; Injections, Intravenous; Methotrexate; Neoplasms; Time Factors	1989

Article

Year

Oral dipyridamole and methotrexate in human solid tumors: a toxicity trial.

Cancer chemotherapy and pharmacology, 1989, Volume: 23, Issue:4

Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Humans; Injections, Intramuscular; Injections, Intravenous; Methotrexate; Neoplasms; Time Factors

1989

Other Studies

49 other study(ies) available for dipyridamole and methotrexate

Article	Year
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:3 Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Membrane; Cyclic AMP; Cyclic GMP; Estradiol; Humans; Immunohistochemistry; Insecta; Kidney Tubules, Proximal; Methotrexate; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Rats; Tissue Distribution	2002
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane. Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:2 Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies; Carcinoma, Hepatocellular; Cell Polarity; Cholagogues and Choleretics; Cricetinae; Fibroblasts; Gene Expression; Glutathione; Hepatocytes; Humans; Liver Neoplasms; Male; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Rats; Taurocholic Acid; Transfection; Transport Vesicles; Tritium	2003
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
InCl European journal of medicinal chemistry, 2019, Jul-15, Volume: 174 Topics: Animals; Arthritis; Cyclic Nucleotide Phosphodiesterases, Type 4; Encephalomyelitis, Autoimmune, Experimental; Freund's Adjuvant; Indium; Indoles; Molecular Structure; Multiple Sclerosis; Oligodendrocyte-Myelin Glycoprotein; Phosphodiesterase 4 Inhibitors; Quinoxalines; Rats; Structure-Activity Relationship; Zebrafish; Zebrafish Proteins	2019
Growth rate of cultured Novikoff rat hepatoma cells as a function of the rate of thymidine and hypoxanthine transport. The Journal of membrane biology, 1977, Jun-06, Volume: 34, Issue:2-3 Topics: Adenosine; Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Dipyridamole; Guanosine; Hypoxanthines; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Rats; Thymidine; Thymine Nucleotides	1977
Azidothymidine and dipyridamole as biochemical response modifiers: synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells. Oncology research, 1992, Volume: 4, Issue:2 Topics: Adenocarcinoma; Cell Division; Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; DNA Replication; Drug Screening Assays, Antitumor; Drug Synergism; Fluorouracil; Humans; Methotrexate; Pancreatic Neoplasms; Thymidine; Tumor Stem Cell Assay; Zidovudine	1992
Role of hypoxanthine and thymidine in determining methotrexate plus dipyridamole cytotoxicity. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cyclic AMP; Dipyridamole; Drug Synergism; Female; Humans; Hypoxanthine; Hypoxanthines; Methotrexate; Ovarian Neoplasms; Thymidine	1990
Dipyridamole-cisplatin potentiation: enhanced in vivo cytotoxicity in xenograft models of human testicular and bladder cancers. The Journal of urology, 1990, Volume: 144, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Cisplatin; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Methotrexate; Mice; Mice, Nude; Neoplasm Transplantation; Testicular Neoplasms; Transplantation, Heterologous; Urinary Bladder Neoplasms	1990
Enhancement of methotrexate cytotoxicity towards the MDA.MB.436 human breast cancer cell line by dipyridamole. The role of methotrexate polyglutamates. Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18 Topics: Arachidonic Acid; Arachidonic Acids; Breast Neoplasms; Cell Count; Cell Line; Dipyridamole; Drug Synergism; Female; Humans; Indomethacin; Methotrexate; Polyglutamic Acid; Time Factors	1986
Dipyridamole potentiates the growth-inhibitory action of methotrexate and 5-fluorouracil in human keratinocytes in vitro. The Journal of investigative dermatology, 1989, Volume: 93, Issue:4 Topics: Cell Division; Dipyridamole; DNA; Drug Synergism; Epidermal Cells; Fluorouracil; Humans; Infant, Newborn; Keratins; Male; Methotrexate; Thymidine	1989
Novel approaches to intraperitoneal drug delivery. Acta medica Austriaca, 1989, Volume: 16, Issue:3-4 Topics: Antineoplastic Agents; Dipyridamole; Dose-Response Relationship, Drug; Drug Evaluation; Drug Synergism; Etoposide; Female; Humans; Infusion Pumps; Infusions, Parenteral; Long-Term Care; Methotrexate; Ovarian Neoplasms; Peritoneal Neoplasms; Tumor Cells, Cultured; Tumor Stem Cell Assay	1989
5-Fluoropyrimidine-induced DNA damage in human colon adenocarcinoma and its augmentation by the nucleoside transport inhibitor dipyridamole. Cancer research, 1989, Mar-01, Volume: 49, Issue:5 Topics: Adenocarcinoma; Colonic Neoplasms; Dipyridamole; DNA; DNA Damage; Floxuridine; Fluorouracil; Humans; Methotrexate; Nucleosides; Tumor Cells, Cultured	1989
[Potentiated antitumor effect of methotrexate by dipyridamole]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1989, Volume: 11, Issue:1 Topics: Amphotericin B; Animals; Antineoplastic Agents; Biological Transport; Dipyridamole; Drug Synergism; Female; Leukemia L1210; Male; Methotrexate; Mice; Nucleosides; Sarcoma 180; Tumor Cells, Cultured	1989
The effects of dipyridamole and indomethacin on methotrexate cytotoxicity in LoVo human colon cancer cells. The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:5 Topics: Cell Division; Cell Survival; Colonic Neoplasms; Dipyridamole; Humans; Indomethacin; Methotrexate; Tumor Cells, Cultured	1989
Pharmacologic basis for the use of dipyridamole to increase the selectivity of intraperitoneally delivered methotrexate. Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:3 Topics: Ascitic Fluid; Cell Line; Dipyridamole; Drug Evaluation, Preclinical; Drug Stability; Drug Synergism; Drug Therapy, Combination; Female; Humans; Infusions, Parenteral; Methotrexate; Ovarian Neoplasms; Protein Binding; Tumor Cells, Cultured; Tumor Stem Cell Assay	1989
Potentiation of antimetabolite antitumor activity in vivo by dipyridamole and amphotericin B. Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:3 Topics: Amphotericin B; Animals; Antimetabolites, Antineoplastic; Dipyridamole; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Lung Neoplasms; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Sarcoma 180; Uterine Cervical Neoplasms	1989
Selective intraperitoneal biochemical modulation of methotrexate by dipyridamole. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Dipyridamole; Drug Interactions; Female; Fever of Unknown Origin; Humans; Infusions, Parenteral; Male; Methotrexate; Middle Aged; Peritoneal Neoplasms; Peritonitis; Prognosis	1989
Methotrexate and dipyridamole combination chemotherapy based upon inhibition of nucleoside salvage in humans. Cancer research, 1989, Apr-01, Volume: 49, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Dipyridamole; Humans; Methotrexate; Neoplasms; Nucleosides	1989
Potentiation of methotrexate lymphocytotoxicity in vitro by inhibitors of nucleoside transport. British journal of cancer, 1989, Volume: 59, Issue:3 Topics: Cell Survival; Cells, Cultured; Dipyridamole; Drug Synergism; Guanosine; Humans; Lymphocytes; Methotrexate; Thionucleosides	1989
Augmentation of methotrexate cytotoxicity in human colon cancer cells achieved through inhibition of thymidine salvage by dipyridamole. Biochemical pharmacology, 1987, Mar-15, Volume: 36, Issue:6 Topics: Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; Drug Synergism; Guanine; Humans; Hypoxanthine; Hypoxanthines; Methotrexate; Rectal Neoplasms; Thymidine; Thymine Nucleotides	1987
Phase II trial of oral methotrexate and dipyridamole in colorectal carcinoma. Cancer treatment reports, 1987, Volume: 71, Issue:9 Topics: Adenocarcinoma; Administration, Oral; Aged; Colonic Neoplasms; Dipyridamole; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Kinetics; Male; Methotrexate; Middle Aged; Rectal Neoplasms	1987
In vitro evaluation of nucleoside transport inhibition in vivo. Journal of pharmacological methods, 1986, Volume: 15, Issue:2 Topics: Animals; Biological Transport; Dipyridamole; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Methotrexate; Mice; Mice, Inbred AKR; Mice, Inbred Strains; Nucleosides; Thymidine; Time Factors	1986
S49 mouse lymphoma cells are deficient in hypoxanthine transport. Biochimica et biophysica acta, 1986, Feb-13, Volume: 855, Issue:1 Topics: Adenine; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Dipyridamole; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lymphoma; Methotrexate; Mice; Permeability; Thymidine; Uridine; Uridine Kinase	1986
Potentiation of methotrexate toxicity by dipyridamole. Cancer research, 1984, Volume: 44, Issue:6 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dipyridamole; DNA Replication; Drug Synergism; Female; Kinetics; Leukemia L1210; Methotrexate; Mice; Mice, Inbred AKR; Mice, Inbred Strains; Osteosarcoma; Ovary	1984
Dipyridamole inhibits reversion by thymidine of methotrexate effect and increases drug uptake in Sarcoma 180 cells. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:10 Topics: Animals; Biological Transport; Deoxycytidine; Deoxyuridine; Dipyridamole; DNA Replication; Drug Antagonism; Kinetics; Methotrexate; Mice; Sarcoma 180; Thymidine; Thymine Nucleotides	1984
Microcalorimetric evaluation of the effect of combined chemotherapeutic drugs. Biochimica et biophysica acta, 1995, Jun-09, Volume: 1244, Issue:2-3 Topics: Antineoplastic Agents; Calorimetry; Cell Death; Dipyridamole; Drug Synergism; Humans; Kinetics; Lymphoma, T-Cell; Mercaptopurine; Methotrexate; Thioguanine; Tumor Cells, Cultured	1995
The enhancement of the frequency of resistance to N-phosphonoacetyl-L-aspartate and methotrexate by 1-beta-D-arabinofuranosylcytosine: the effect of dipyridamole. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2 Topics: Animals; Aspartic Acid; Cell Line, Transformed; Cricetinae; Cytarabine; Dipyridamole; Drug Resistance; Drug Synergism; Humans; Methotrexate; Nucleosides; Phosphonoacetic Acid; Thioinosine	1994
Selective modulation of vinblastine sensitivity by 1,9-dideoxyforskolin and related diterpenes in multidrug resistant tumour cells. British journal of cancer, 1993, Volume: 67, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bucladesine; Colforsin; Cyclic AMP; Dipyridamole; Doxorubicin; Drug Resistance; Humans; Membrane Glycoproteins; Methotrexate; Mice; Neoplasm Proteins; Regression Analysis; Tumor Cells, Cultured; Vinblastine	1993
Mechanism of the discrepant effect of a combination of methotrexate plus dipyridamole on human hematologic cell lines. Japanese journal of clinical oncology, 1993, Volume: 23, Issue:4 Topics: Adult; Cell Division; Child; Dipyridamole; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Infant; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Tumor Cells, Cultured	1993
The influence of BIBW22BS, a dipyridamole derivative, on the antiproliferative effects of 5-fluorouracil, methotrexate and gemcitabine in vitro and in human tumour xenografts. European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:13-14 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Deoxycytidine; Dipyridamole; Doxorubicin; Drug Resistance; Female; Floxuridine; Fluorouracil; Gemcitabine; Humans; Methotrexate; Mice; Mice, Nude; Morpholines; Neoplasms; Neoplasms, Experimental; Protein Binding; Transplantation, Heterologous; Triamterene; Tumor Cells, Cultured; Vincristine	1995
Dipyridamole mediated enhanced antiproliferative activity of 10-ethyl-10-deazaaminopterin (10-EDAM) against human lung cancer cell lines. Journal of cellular biochemistry. Supplement, 1996, Volume: 24 Topics: Aminopterin; Biological Transport; Cell Division; Depression, Chemical; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Folic Acid Antagonists; Growth Inhibitors; Humans; Lung Neoplasms; Methotrexate; Nucleosides; Thymidine; Tumor Cells, Cultured	1996
Maintenance of differential methotrexate toxicity between cells expressing drug-resistant and wild-type dihydrofolate reductase activities in the presence of nucleosides through nucleoside transport inhibition. Biochemical pharmacology, 2000, Jan-15, Volume: 59, Issue:2 Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Carrier Proteins; Dipyridamole; Drug Resistance, Neoplasm; Humans; K562 Cells; Membrane Proteins; Methotrexate; Mice; Nucleoside Transport Proteins; Nucleosides; Phosphodiesterase Inhibitors; Tetrahydrofolate Dehydrogenase	2000
Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells. The Journal of biological chemistry, 2001, Oct-26, Volume: 276, Issue:43 Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Biological Transport; Breast Neoplasms; Carrier Proteins; CpG Islands; Decitabine; Dipyridamole; DNA Methylation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Female; Folic Acid Antagonists; Gene Silencing; Histone Deacetylases; Histones; Humans; Ion Pumps; Membrane Transport Proteins; Methotrexate; Promoter Regions, Genetic; Reduced Folate Carrier Protein	2001
Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs. Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Bone Neoplasms; Cattle; Culture Media; Cytarabine; Dialysis; Dipyridamole; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Fetal Blood; Humans; Hypoxanthine; Methotrexate; Neoplasm Proteins; Nucleotides; Osteosarcoma; Tetrahydrofolate Dehydrogenase; Thymidine; Tumor Cells, Cultured; Vidarabine	2002
Methotrexate modulates the kinetics of adenosine in humans in vivo. Annals of the rheumatic diseases, 2006, Volume: 65, Issue:4 Topics: Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Female; Forearm; Hemodynamics; Humans; Male; Methotrexate; Middle Aged; Regional Blood Flow; Severity of Illness Index; Vasodilation; Vasodilator Agents	2006
Methotrexate resistance in vitro is achieved by a dynamic selectionprocess of tumor cell variants emerging during treatment. International journal of cancer, 2006, Oct-01, Volume: 119, Issue:7 Topics: Cell Line, Tumor; Cell Proliferation; Chromosomal Instability; Dipyridamole; Drug Resistance, Neoplasm; Genetic Variation; Humans; Methotrexate; Neoplasms; Nucleosides; Selection, Genetic	2006
A new agent for tumour necrosis factor-alpha inhibition: In vitro effects of dipyridamole in Crohn's disease. Scandinavian journal of clinical and laboratory investigation, 2009, Volume: 69, Issue:6 Topics: Adolescent; Adult; Case-Control Studies; Crohn Disease; Dipyridamole; Dose-Response Relationship, Drug; Female; Humans; Interleukin-10; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Methotrexate; Middle Aged; Phytohemagglutinins; Tumor Necrosis Factor-alpha; Young Adult	2009
Effects of extracellular purines on cytotoxicity of methotrexate. Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:1 Topics: Animals; Antimetabolites, Antineoplastic; Cell Survival; Culture Media, Conditioned; Deoxyribonucleotides; Dipyridamole; Drug Synergism; Hypoxanthine; Leukemia L1210; Methotrexate; Mice; Purines; Tumor Stem Cell Assay	2010
Sleeping Beauty-Mediated Drug Resistance Gene Transfer in Human Hematopoietic Progenitor Cells. Human gene therapy, 2015, Volume: 26, Issue:10 Topics: Antigens, CD34; Dipyridamole; DNA Transposable Elements; Drug Resistance; Gene Transfer Techniques; Genetic Therapy; Green Fluorescent Proteins; Hematopoietic Stem Cells; Humans; Methotrexate; Tetrahydrofolate Dehydrogenase	2015