dipyridamole and hypoxanthine

dipyridamole has been researched along with hypoxanthine in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199018 (47.37)18.7374
1990's12 (31.58)18.2507
2000's7 (18.42)29.6817
2010's1 (2.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mentzer, RM; Van Wylen, DG; Wang, T1
González, R; Pascual, C; Romay, C1
Ambrosio, S; Ballarín, M; Fredholm, BB; Mahy, N1
Granger, HJ; Meininger, CJ1
de Jong, JW; Den Boer, PJ; Grootegoed, JA; Mackenbach, P1
Chan, TC; Howell, SB1
Beck, J; Ullman, B1
Bonanni, LC; Divo, AA; Geary, TG; Jensen, JB1
Plagemann, PG; Woffendin, C; Wohlhueter, RM1
Wheeler, CP; Yudilevich, DL1
Berne, RM; Rubio, R; Shryock, JC1
Kather, H1
Aronow, B; Ullman, B1
Aronow, B; Hollingsworth, P; McCartan, K; Patrick, J; Toll, D; Ullman, B1
Bassingthwaighte, JB; Sparks, HV1
Fischer, PH; Pangallo, CA; Van Mouwerik, TJ; Willson, JK1
Kraupp, M; Plagemann, PG1
Klem, J; Kopff, M; Zachara, B; Zakrzewska, I1
Ehinger, BE; Fredholm, BB; Lindström, K; Perez, MT1
Plagemann, PG; Wohlhueter, RM2
Kulkarni, SK; Mehta, AK1
Hellewell, PG; Pearson, JD1
Fredholm, BB; Lerner, U1
Griffith, DA; Jarvis, SM1
Meno, JR; Ngai, AC; Winn, HR1
Aherne, GW; Curtin, NJ; Turner, RN1
Foga, IO; Geiger, JD; Hasinoff, BB; Nath, A1
Calvert, AH; Campbell, FC; Curtin, NJ; Dickinson, AM; Marshman, E; Newell, DR; Patel, HR1
Calvert, AH; Curtin, NJ; Marshman, E; Newell, DR; Smith, PG1
Henze, A; Ronquist, G; Thelin, S; Waldenström, A; Wikström, G; Zemgulis, V1
Curtin, NJ; Marshman, E; Newell, DR; Taylor, GA; Thomas, HD1
Barlow, HC; Calvert, AH; Curtin, NJ; Golding, BT; Griffin, RJ; Newell, DR; Smith, PG; Thomas, HD1
Baldwin, SA; Cass, CE; Ng, AM; Sundaram, M; Vickers, MF; Yao, SY; Young, JD1
Cole, PD; Kamen, BA; Smith, AK1
Al Safarjalani, ON; El Kouni, MH; Naguib, FN1
Bone, DB; Hammond, JR1
Bartier, WA; Chong, L; Ma, G; Tattersall, MH1

Reviews

2 review(s) available for dipyridamole and hypoxanthine

ArticleYear
Nucleoside and nucleobase transport in animal cells.
    Biochimica et biophysica acta, 1988, Oct-11, Volume: 947, Issue:3

    Topics: Adenine; Algorithms; Animals; Biological Transport; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Kinetics; Lidoflazine; Monosaccharide Transport Proteins; Nucleosides; Temperature; Thioinosine; Thionucleosides

1988
Indicator dilution estimation of capillary endothelial transport.
    Annual review of physiology, 1986, Volume: 48

    Topics: Adenosine; Amino Acids; Animals; Arabinonucleosides; Blood-Brain Barrier; Capillary Permeability; Cats; Cell Membrane Permeability; Diffusion; Dipyridamole; Dogs; Dye Dilution Technique; Endothelium; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Mathematics; Models, Cardiovascular; Prostaglandins; Serum Albumin, Radio-Iodinated; Sucrose

1986

Other Studies

36 other study(ies) available for dipyridamole and hypoxanthine

ArticleYear
Interstitial adenosine with dipyridamole: effect of adenosine receptor blockade and adenosine deaminase.
    The American journal of physiology, 1992, Volume: 263, Issue:2 Pt 2

    Topics: Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Dialysis; Dipyridamole; Dogs; Extracellular Space; Female; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Male; Purinergic Antagonists; Theophylline

1992
Drugs effects on superoxide generation and chemiluminescence response of human leukocytes.
    Agents and actions, 1991, Volume: 32, Issue:3-4

    Topics: Catechin; Dipyridamole; Ditiocarb; Humans; Hypoxanthine; Hypoxanthines; Leukocytes; Luminescent Measurements; Luminol; Opsonin Proteins; Saccharomyces cerevisiae; Superoxides; Verapamil; Xanthine Oxidase

1991
Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism.
    Acta physiologica Scandinavica, 1991, Volume: 142, Issue:1

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Biological Transport, Active; Corpus Striatum; Dipyridamole; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Male; Pentostatin; Rats; Rats, Inbred Strains

1991
Mechanisms leading to adenosine-stimulated proliferation of microvascular endothelial cells.
    The American journal of physiology, 1990, Volume: 258, Issue:1 Pt 2

    Topics: Adenosine; Animals; Biomechanical Phenomena; Cell Division; Cyclic AMP; Dideoxyadenosine; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypoxanthine; Hypoxanthines; Inosine; Isomerism; Microcirculation; Molecular Weight; Thioinosine

1990
Effects of glucose and adenosine on the ATP content of hamster spermatids.
    Reproduction, fertility, and development, 1990, Volume: 2, Issue:2

    Topics: Adenine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cricetinae; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Fructose; Galactose; Glucose; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Mannose; Spermatids; Tubercidin

1990
Role of hypoxanthine and thymidine in determining methotrexate plus dipyridamole cytotoxicity.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line; Cyclic AMP; Dipyridamole; Drug Synergism; Female; Humans; Hypoxanthine; Hypoxanthines; Methotrexate; Ovarian Neoplasms; Thymidine

1990
Expression of a novel high affinity purine base transport system in mutant mouse S49 cells does not require a functional nucleoside transporter.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenine; Animals; Biological Transport; Clone Cells; Dipyridamole; Dose-Response Relationship, Drug; Gene Expression; Guanine; Hybridization, Genetic; Hypoxanthine; Hypoxanthines; Inosine; Lymphoma; Mice; Mice, Inbred BALB C; Mutation; Phenotype; T-Lymphocytes; Thioinosine; Tumor Cells, Cultured

1989
Nutritional requirements of Plasmodium falciparum in culture. III. Further observations on essential nutrients and antimetabolites.
    The Journal of protozoology, 1985, Volume: 32, Issue:4

    Topics: 4-Aminobenzoic Acid; Animals; Antimetabolites; Biotin; Buthionine Sulfoximine; Carbohydrate Metabolism; Culture Media; Dipyridamole; Folic Acid; Glutamates; Glutamic Acid; Hypoxanthine; Hypoxanthines; Isoniazid; Leucovorin; Methionine Sulfoximine; Plasmodium falciparum; Purines; Pyridoxine; Sulfonamides

1985
Transport and metabolism of adenosine in the perfused guinea-pig placenta.
    The Journal of physiology, 1988, Volume: 405

    Topics: Adenosine; Animals; Biological Transport; Dipyridamole; Female; Guinea Pigs; Hypoxanthine; Hypoxanthines; Inosine; Maternal-Fetal Exchange; Placenta; Pregnancy; Thioinosine; Tritium; Uric Acid

1988
Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition.
    The American journal of physiology, 1988, Volume: 254, Issue:2 Pt 2

    Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Cells, Cultured; Dipyridamole; Endothelium, Vascular; Glycolysis; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Iodoacetates; Iodoacetic Acid; Male; Oxidative Phosphorylation; Potassium; Sodium; Sodium Cyanide; Swine; Vasodilation

1988
Purine accumulation in human fat cell suspensions. Evidence that human adipocytes release inosine and hypoxanthine rather than adenosine.
    The Journal of biological chemistry, 1988, Jun-25, Volume: 263, Issue:18

    Topics: Adenine Nucleotides; Adenosine; Adipose Tissue; Biological Transport; Cells, Cultured; Dipyridamole; Female; Humans; Hypoxanthine; Hypoxanthines; Inosine; Isoproterenol; Kinetics; Reference Values

1988
Role of the nucleoside transport function in the transport and salvage of purine nucleobases.
    The Journal of biological chemistry, 1986, Feb-15, Volume: 261, Issue:5

    Topics: Adenine; Animals; Antimetabolites, Antineoplastic; Azaserine; Biological Transport; Cell Line; Dipyridamole; Hypoxanthine; Hypoxanthines; Mice; Nucleosides; Purines; T-Lymphocytes; Thioinosine

1986
Expression of a novel high-affinity purine nucleobase transport function in mutant mammalian T lymphoblasts.
    Molecular and cellular biology, 1986, Volume: 6, Issue:8

    Topics: Adenine; Animals; Azaserine; Biological Transport, Active; Cell Line; Dipyridamole; Guanine; Hypoxanthine; Hypoxanthines; Kinetics; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Phenotype; Purine Nucleosides; T-Lymphocytes; Thioinosine

1986
Augmentation of methotrexate cytotoxicity in human colon cancer cells achieved through inhibition of thymidine salvage by dipyridamole.
    Biochemical pharmacology, 1987, Mar-15, Volume: 36, Issue:6

    Topics: Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; Drug Synergism; Guanine; Humans; Hypoxanthine; Hypoxanthines; Methotrexate; Rectal Neoplasms; Thymidine; Thymine Nucleotides

1987
Inhibition of nucleoside and nucleobase transport and nitrobenzylthioinosine binding by dilazep and hexobendine.
    Biochemical pharmacology, 1986, Aug-01, Volume: 35, Issue:15

    Topics: Animals; Azepines; Benzoates; Biological Transport; Carbon Radioisotopes; Cell Line; Cricetinae; Cricetulus; Dilazep; Dipyridamole; Erythrocytes; Hexobendine; Humans; Hypoxanthine; Hypoxanthines; Inosine; Mice; Nucleosides; Rats; Thioinosine; Uridine

1986
Effect of dipyridamole on adenine incorporation into hypoxanthine nucleotides of fresh red blood cells.
    Biomedica biochimica acta, 1986, Volume: 45, Issue:7

    Topics: Adenine; Biological Transport; Carbon Radioisotopes; Dipyridamole; Erythrocytes; Humans; Hypoxanthine; Hypoxanthines; Inosine Monophosphate; Inosine Nucleotides

1986
Release of endogenous and radioactive purines from the rabbit retina.
    Brain research, 1986, Nov-19, Volume: 398, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Animals; Dipyridamole; Evoked Potentials; Female; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Male; Potassium; Purines; Rabbits; Retina; Tritium

1986
S49 mouse lymphoma cells are deficient in hypoxanthine transport.
    Biochimica et biophysica acta, 1986, Feb-13, Volume: 855, Issue:1

    Topics: Adenine; Animals; Biological Transport; Cell Line; Cricetinae; Cricetulus; Dipyridamole; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lymphoma; Methotrexate; Mice; Permeability; Thymidine; Uridine; Uridine Kinase

1986
Mechanism of potentiation by diazepam of adenosine response.
    Life sciences, 1984, Jan-02, Volume: 34, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Animals; Benzodiazepinones; Cecum; Diazepam; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Female; Flumazenil; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Inbred Strains

1984
Hypoxanthine transport in mammalian cells: cell type-specific differences in sensitivity to inhibition by dipyridamole and uridine.
    The Journal of membrane biology, 1984, Volume: 81, Issue:3

    Topics: Animals; Biological Transport; Carcinoma, Ehrlich Tumor; Cell Line; Cricetinae; Cricetulus; Dipyridamole; Female; Hypoxanthine; Hypoxanthines; Kinetics; L Cells; Leukemia, Experimental; Liver Neoplasms, Experimental; Mice; Ovary; Rats; Species Specificity; Tritium; Uridine

1984
Metabolism of circulating adenosine by the porcine isolated perfused lung.
    Circulation research, 1983, Volume: 53, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Animals; Dipyridamole; Hypoxanthine; Hypoxanthines; In Vitro Techniques; Inosine; Lung; Perfusion; Swine; Tubercidin

1983
Metabolism of adenosine and 2'-deoxy-adenosine by fetal mouse calvaria in culture.
    Medical biology, 1982, Volume: 60, Issue:5

    Topics: Adenine; Adenosine; Animals; Bone and Bones; Culture Media; Deoxyadenosines; Dilazep; Dipyridamole; Hypoxanthine; Hypoxanthines; Inosine; Mice; Organ Culture Techniques

1982
High affinity sodium-dependent nucleobase transport in cultured renal epithelial cells (LLC-PK1).
    The Journal of biological chemistry, 1993, Sep-25, Volume: 268, Issue:27

    Topics: Animals; Biological Transport; Cations, Monovalent; Cell Line; Dilazep; Dipyridamole; Epithelium; Hypoxanthine; Hypoxanthines; Kidney; Kinetics; Nucleosides; Purines; Pyrimidines; Sodium; Thioinosine; Tritium

1993
Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:2

    Topics: Adenine; Adenosine; Animals; Arterioles; Cerebrovascular Circulation; Dipyridamole; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Male; Pia Mater; Rats; Rats, Sprague-Dawley; Vasodilation

1993
Selective potentiation of lometrexol growth inhibition by dipyridamole through cell-specific inhibition of hypoxanthine salvage.
    British journal of cancer, 1997, Volume: 76, Issue:10

    Topics: Antimetabolites, Antineoplastic; Biological Transport; Deoxyguanine Nucleotides; Dipyridamole; Drug Synergism; Humans; Hypoxanthine; Tetrahydrofolates; Tumor Cells, Cultured

1997
Antioxidants and dipyridamole inhibit HIV-1 gp120-induced free radical-based oxidative damage to human monocytoid cells.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Dec-01, Volume: 16, Issue:4

    Topics: Anti-HIV Agents; Antioxidants; Dipyridamole; Dose-Response Relationship, Drug; HIV Antibodies; HIV Envelope Protein gp120; HIV Seronegativity; HIV Seropositivity; HIV-1; Humans; Hypoxanthine; Monocytes; Oxidative Stress; Reactive Oxygen Species; Tumor Cells, Cultured; Xanthine

1997
Dipyridamole potentiates antipurine antifolate activity in the presence of hypoxanthine in tumor cells but not in normal tissues in vitro.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:11

    Topics: Adenosine Triphosphate; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Division; Dipyridamole; Drug Synergism; Folic Acid Antagonists; Growth Inhibitors; Hematopoietic Stem Cells; Humans; Hypoxanthine; Intestinal Mucosa; Intestines; K562 Cells; Mice; Mice, Inbred BALB C; Tetrahydrofolates; Tumor Cells, Cultured

1998
Prevention of thymidine and hypoxanthine rescue from MTA (LY231514) growth inhibition by dipyridamole in human lung cancer cell lines.
    Seminars in oncology, 1999, Volume: 26, Issue:2 Suppl 6

    Topics: Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cell Division; Dipyridamole; Enzyme Inhibitors; Folic Acid Antagonists; Glutamates; Guanine; Humans; Hypoxanthine; Lung Neoplasms; Pemetrexed; Phosphodiesterase Inhibitors; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1999
Nucleoside transport inhibition in ischemic myocardium results in enhanced taurine efflux.
    European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2

    Topics: Adenosine; Animals; Biological Transport; Dipyridamole; Hypoxanthine; Inosine; Lactates; Microdialysis; Myocardial Ischemia; Nucleosides; Pyruvic Acid; Swine; Taurine; Vasodilator Agents

2001
Hypoxanthine transport in human tumour cell lines: relationship to the inhibition of hypoxanthine rescue by dipyridamole.
    Biochemical pharmacology, 2001, Feb-15, Volume: 61, Issue:4

    Topics: Affinity Labels; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Division; Chromatography, High Pressure Liquid; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Equilibrative Nucleoside Transport Proteins; Folic Acid Antagonists; Humans; Hypoxanthine; Kinetics; Phosphodiesterase Inhibitors; Sodium; Thioinosine; Thymidine; Tumor Cells, Cultured

2001
In vitro and in vivo properties of novel nucleoside transport inhibitors with improved pharmacological properties that potentiate antifolate activity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:7

    Topics: Animals; Carrier Proteins; Cell Division; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Female; Folic Acid Antagonists; Glutamates; Guanine; Humans; Hypoxanthine; Liver; Membrane Proteins; Mice; Mice, Inbred BALB C; Nucleoside Transport Proteins; Orosomucoid; Pemetrexed; Tetrahydrofolates; Thymidine; Time Factors; Tritium; Tumor Cells, Cultured

2001
Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation.
    The Journal of biological chemistry, 2002, Jul-12, Volume: 277, Issue:28

    Topics: Animals; Chimera; Dipyridamole; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Humans; Hypoxanthine; Kinetics; Membrane Transport Proteins; Nucleosides; Rats; Recombinant Proteins; Saccharomyces cerevisiae; Xenopus laevis

2002
Osteosarcoma cells, resistant to methotrexate due to nucleoside and nucleobase salvage, are sensitive to nucleoside analogs.
    Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Bone Neoplasms; Cattle; Culture Media; Cytarabine; Dialysis; Dipyridamole; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Fetal Blood; Humans; Hypoxanthine; Methotrexate; Neoplasm Proteins; Nucleotides; Osteosarcoma; Tetrahydrofolate Dehydrogenase; Thymidine; Tumor Cells, Cultured; Vidarabine

2002
Uptake of nitrobenzylthioinosine and purine beta-L-nucleosides by intracellular Toxoplasma gondii.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:10

    Topics: Animals; Biological Transport; Cells, Cultured; Dipyridamole; Fibroblasts; Humans; Hypoxanthine; Mice; Mice, Inbred Strains; Nucleoside Transport Proteins; Purine Nucleosides; Stereoisomerism; Thioinosine; Toxoplasma

2003
Nucleoside and nucleobase transporters of primary human cardiac microvascular endothelial cells: characterization of a novel nucleobase transporter.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6

    Topics: 2-Chloroadenosine; Animals; Cell Culture Techniques; Cell Line; Cells, Cultured; Child, Preschool; Coronary Vessels; Dilazep; Dipyridamole; Dogs; Endothelial Cells; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Female; Humans; Hypoxanthine; Kinetics; Microcirculation; Nucleobase Transport Proteins; Piperazines; Protein Binding; Purines; Rats; Swine; Thioinosine; Transfection; Tritium

2007
Effects of extracellular purines on cytotoxicity of methotrexate.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Survival; Culture Media, Conditioned; Deoxyribonucleotides; Dipyridamole; Drug Synergism; Hypoxanthine; Leukemia L1210; Methotrexate; Mice; Purines; Tumor Stem Cell Assay

2010