dipyridamole and guanine

dipyridamole has been researched along with guanine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's1 (10.00)18.2507
2000's4 (40.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gozalbes, R; Pineda-Lucena, A1
Plagemann, PG; Zylka, JM1
Beck, J; Ullman, B1
Aronow, B; Hollingsworth, P; McCartan, K; Patrick, J; Toll, D; Ullman, B1
Fischer, PH; Pangallo, CA; Van Mouwerik, TJ; Willson, JK1
Calvert, AH; Curtin, NJ; Marshman, E; Newell, DR; Smith, PG1
Curtin, NJ; Marshman, E; Newell, DR; Smith, PG1
Barlow, HC; Calvert, AH; Curtin, NJ; Golding, BT; Griffin, RJ; Newell, DR; Smith, PG; Thomas, HD1
Curigliano, G; Danesi, R; De Braud, F; De Cobelli, O; Del Tacca, M; Giovannetti, E; Mey, V; Nannizzi, S; Pece, S; Verweij, F1
Barlow, H; Barton, M; Curtin, NJ; Golding, BT; Griffin, RJ; Lin, MJ; Newell, DR; Northen, JS; Saravanan, K; Thomas, HD; Wang, LZ1

Trials

1 trial(s) available for dipyridamole and guanine

ArticleYear
In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients.
    British journal of cancer, 2006, Aug-07, Volume: 95, Issue:3

    Topics: Administration, Intravesical; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Deoxycytidine Kinase; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Equilibrative Nucleoside Transporter 1; Excitatory Amino Acid Antagonists; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Glutamates; Guanine; Humans; Male; Middle Aged; Neoplasm Staging; Pemetrexed; Phosphoribosylglycinamide Formyltransferase; Phosphorylation; Proto-Oncogene Proteins c-akt; S Phase; Thioinosine; Thymidylate Synthase; Treatment Outcome; Urinary Bladder Neoplasms

2006

Other Studies

9 other study(ies) available for dipyridamole and guanine

ArticleYear
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Purine and pyrimidine transport by cultured Novikoff cells. Specificities and mechanism of transport and relationship to phosphoribosylation.
    The Journal of biological chemistry, 1975, Aug-10, Volume: 250, Issue:15

    Topics: Adenine; Animals; Biological Transport, Active; Calorimetry; Carcinoma, Hepatocellular; Cell Line; Centrifugation, Density Gradient; Chloromercuribenzoates; Cytochalasin B; Cytosine; Dipyridamole; Dithiothreitol; Guanine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Pentosyltransferases; Purines; Pyrimidines; Rats; Thermodynamics; Time Factors; Uracil

1975
Expression of a novel high affinity purine base transport system in mutant mouse S49 cells does not require a functional nucleoside transporter.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Adenine; Animals; Biological Transport; Clone Cells; Dipyridamole; Dose-Response Relationship, Drug; Gene Expression; Guanine; Hybridization, Genetic; Hypoxanthine; Hypoxanthines; Inosine; Lymphoma; Mice; Mice, Inbred BALB C; Mutation; Phenotype; T-Lymphocytes; Thioinosine; Tumor Cells, Cultured

1989
Expression of a novel high-affinity purine nucleobase transport function in mutant mammalian T lymphoblasts.
    Molecular and cellular biology, 1986, Volume: 6, Issue:8

    Topics: Adenine; Animals; Azaserine; Biological Transport, Active; Cell Line; Dipyridamole; Guanine; Hypoxanthine; Hypoxanthines; Kinetics; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mutation; Phenotype; Purine Nucleosides; T-Lymphocytes; Thioinosine

1986
Augmentation of methotrexate cytotoxicity in human colon cancer cells achieved through inhibition of thymidine salvage by dipyridamole.
    Biochemical pharmacology, 1987, Mar-15, Volume: 36, Issue:6

    Topics: Cell Line; Cell Survival; Colonic Neoplasms; Dipyridamole; Drug Synergism; Guanine; Humans; Hypoxanthine; Hypoxanthines; Methotrexate; Rectal Neoplasms; Thymidine; Thymine Nucleotides

1987
Prevention of thymidine and hypoxanthine rescue from MTA (LY231514) growth inhibition by dipyridamole in human lung cancer cell lines.
    Seminars in oncology, 1999, Volume: 26, Issue:2 Suppl 6

    Topics: Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cell Division; Dipyridamole; Enzyme Inhibitors; Folic Acid Antagonists; Glutamates; Guanine; Humans; Hypoxanthine; Lung Neoplasms; Pemetrexed; Phosphodiesterase Inhibitors; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1999
Dipyridamole potentiates the in vitro activity of MTA (LY231514) by inhibition of thymidine transport.
    British journal of cancer, 2000, Volume: 82, Issue:4

    Topics: Biological Transport; Dipyridamole; Drug Synergism; Enzyme Inhibitors; Glutamates; Guanine; Humans; Pemetrexed; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

2000
In vitro and in vivo properties of novel nucleoside transport inhibitors with improved pharmacological properties that potentiate antifolate activity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:7

    Topics: Animals; Carrier Proteins; Cell Division; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Female; Folic Acid Antagonists; Glutamates; Guanine; Humans; Hypoxanthine; Liver; Membrane Proteins; Mice; Mice, Inbred BALB C; Nucleoside Transport Proteins; Orosomucoid; Pemetrexed; Tetrahydrofolates; Thymidine; Time Factors; Tritium; Tumor Cells, Cultured

2001
Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:7

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Proliferation; Dipyridamole; Drug Synergism; Female; Folic Acid Antagonists; Glutamates; Guanine; Humans; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Nucleosides; Orosomucoid; Pemetrexed; Phosphorylation; Prodrugs; Thymidine; Thymidylate Synthase; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2009