dipyridamole and cyclic gmp

dipyridamole has been researched along with cyclic gmp in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (17.74)	18.7374
1990's	21 (33.87)	18.2507
2000's	25 (40.32)	29.6817
2010's	5 (8.06)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Balzarini, J; Borst, P; De Haas, M; Reid, G; Van Deemter, L; Wielinga, P; Wijnholds, J; Zelcer, N	1
McElroy, FA; Philip, RB	1
Asano, T; Hidaka, H; Ochiai, Y	1
Bendtzen, K; Palit, J	1
Best, LC; Holland, TK; Jones, PB; Martin, TJ; McGuire, MB; Preston, FE; Russell, RG; Segal, DS	1
Kobayashi, A; Ogawa, K	1
Hait, WN; Weiss, B	1
Bai, L; Miyazaki, M; Namba, M; Wahid, S	1
Gauthier, C; Le Bec, A; Lugnier, C; Soustre, H	1
Robichon, A	1
Angielski, S; Kuchta, G; Redlak, M; Szczepańska-Konkel, M	1
Jahr, CE; Nawy, S	1
Moreno, S; Tomes, C	1
Akaishi, Y; Fukao, M; Kobayashi, T; Makita, MA; Makita, Y; Matsuno, K; Miyazaki, T; Sakuma, I; Yasuda, H	1
Diocee, BK; Martin, W; Moodie, SA; Souness, JE	1
Beavo, JA; Gillespie, PG	1
Poltavchenko, GM; Sokolova, EN	1
Ahlner, J; Andersson, RG; Axelsson, KL; Dahlström, U; Rydell, EL	1
Bousseau-Lafortune, S; Coquil, JF; Franks, DJ; Hamet, P; Tremblay, J	1
Abboud, HE; Dousa, TP	1
Ahlner, J; Torfgård, KE	1
Saeki, T; Saito, I	1
Anfossi, G; Cavalot, F; Massucco, P; Mattiello, L; Mularoni, E; Piretto, V; Trovati, M	1
Hartell, NA	1
Amemiya, M; Asano, Y; Iimura, O; Ikeda, U; Kusano, E; Muto, S; Shimada, K	1
Bode, DC; Buchholz, RA; De Garavilla, L; Dundore, R; Jackson, KN; Pagani, ED; Pratt, P; Silver, PJ; Volberg, ML	1
Cheng, JB; Cohan, VL; Eskra, JD; Griffiths, RJ; Pazoles, CJ; Pettipher, ER; Showell, HJ; Turner, CR; Watson, JW	1
Bell, A; Hipps, R; Meadow, W; Rudinsky, B	1
Abman, SH; Clarke, WR; Ivy, DD; Kinsella, JP; Wiggins, JW; Ziegler, JW	1
Dukarm, RC; Morin, FC; Russell, JA; Steinhorn, RH	1
Fyhrquist, F; Saijonmaa, O	1
Barba, G; Donald, A; MacAllister, RJ; Mullen, MJ	1
Mullan, M; Paris, D; Town, T	1
Aigrain, Y; de Lagausie, P; Dinh-Xuan, AT; Forgues, D; Mercier, JC; Thébaud, B	1
Humphrey, J; Mullan, M; Paris, D; Parker, T; Town, T	1
Blanco, E; De La Cruz, JP; Sánchez de la Cuesta, F	1
Blaise, G; Costachescu, T; Derouin, M; Jiang, ZY	1
Abraham, RZ; Kobzik, L; Moody, MR; Reid, MB; Stamler, JS	1
Edvinsson, L; Jansen-Olesen, I; Khurana, TS; Kruuse, C; Olesen, J; Rybalkin, SD	1
Baba, A; Enomoto, R; Lee, E; Matsuda, T; Mori, K; Takuma, K	1
Enke, B; Forssmann, WG; Ghofrani, HA; Grimminger, F; Schermuly, RT; Seeger, W; Walmrath, D; Weissmann, N	1
Naik, JS; Walker, BR	1
Huang, Y; Kong, SK; Kwan, HY; Yao, X	1
De Wolf, D; Foubert, L; Mareels, K; Mortier, E; Reyntjens, K; Van Belleghem, Y; Van Nooten, G	1
Fujita, T; Goto, A; Onozato, ML; Tojo, A	1
Aktas, B; Geiger, J; Hoenig-Liedl, P; Utz, A; Walter, U	1
Baskakov, MB; D'yakova, EY; Kapilevich, LV; Kovalev, IV; Nosarev, AV	1
De Somer, F; De Wolf, D; Foubert, L; Mortier, E; Reyntjens, K; Van Belleghem, Y; Van Nooten, G	1
Azegami, Y; Kaneda, T; Nakajyo, S; Shimizu, K; Urakawa, N; Yamamoto, H	1
Drake, MJ; Gillespie, JI	1
Cogolludo, Al; Lodi, F; Losada, B; Lugnier, C; Moreno, L; Moro, M; Pérez-Vizcaíno, F; Tamargo, J; Villamor, E	1
Barile, L; Giacomello, A; Lupi, F; Messina, E	1
Abraham, R; Biaggioni, I; Diedrich, A; Farley, G; Gamboa, A; Paranjape, SY; Shibao, C	1
Blumenthal, DK; Cheung, AK; Masaki, T; Zhuplatov, SB	1
Jaworski, K; Kopcewicz, J; Szmidt-Jaworska, A	1
Kim, HH; Liao, JK	1
Alvarez, E; Cairrão, E; Morgado, M; Santos-Silva, AJ; Verde, I	1
Døskeland, SO; Holmsen, H; Jensen, BO; Kleppe, R; Kopperud, R; Nygaard, G; Selheim, F	1
Calabriso, N; Carluccio, MA; De Caterina, R; Martines, G; Massaro, M; Pellegrino, M; Scoditti, E; Storelli, C	1
Chang, KH; Kim, YG; Lee, MY; Liu, Y; Oh, SJ	1
Aronsen, L; Lysaa, R; Orvoll, E; Ravna, AW; Sager, G	1
Botigelli, RC; Castro, FC; Del Collado, M; Fernandes, H; Leal, CLV; Schwarz, KL; Zaffalon, FG	1

Reviews

2 review(s) available for dipyridamole and cyclic gmp

Article	Year
Glyceryl trinitrate enhances the adenosine-induced inhibition of platelet responses: a mechanism potentially involved in the in vivo anti-aggregating effects of organic nitrates. Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:11 Topics: Adenosine; Adult; Cyclic AMP; Cyclic GMP; Dipyridamole; Drug Interactions; Humans; Male; Nitroglycerin; Platelet Aggregation; Platelet Aggregation Inhibitors; Vasodilator Agents	1995
Translational therapeutics of dipyridamole. Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:3 Topics: Acute Coronary Syndrome; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; Disease Models, Animal; Endothelium, Vascular; Humans; Mice; Nitric Oxide; Oxidation-Reduction; Phosphodiesterase Inhibitors; Platelet Aggregation; Prognosis; Stroke; Survival Rate; Treatment Outcome	2008

Article

Year

Glyceryl trinitrate enhances the adenosine-induced inhibition of platelet responses: a mechanism potentially involved in the in vivo anti-aggregating effects of organic nitrates.

Clinical and experimental pharmacology & physiology, 1995, Volume: 22, Issue:11

Topics: Adenosine; Adult; Cyclic AMP; Cyclic GMP; Dipyridamole; Drug Interactions; Humans; Male; Nitroglycerin; Platelet Aggregation; Platelet Aggregation Inhibitors; Vasodilator Agents

1995

Translational therapeutics of dipyridamole.

Arteriosclerosis, thrombosis, and vascular biology, 2008, Volume: 28, Issue:3

Topics: Acute Coronary Syndrome; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; Disease Models, Animal; Endothelium, Vascular; Humans; Mice; Nitric Oxide; Oxidation-Reduction; Phosphodiesterase Inhibitors; Platelet Aggregation; Prognosis; Stroke; Survival Rate; Treatment Outcome

2008

Trials

3 trial(s) available for dipyridamole and cyclic gmp

Article	Year
Effect of low dose of dipyridamole on glyceryl trinitrate tolerance in healthy volunteers. Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:4 Topics: Adult; Blood Pressure; Cyclic GMP; Dipyridamole; Double-Blind Method; Drug Tolerance; Female; Heart Rate; Humans; Male; Nitroglycerin	1993
Dipyridamole enhances NO/cGMP-mediated vasodilator-stimulated phosphoprotein phosphorylation and signaling in human platelets: in vitro and in vivo/ex vivo studies. Stroke, 2003, Volume: 34, Issue:3 Topics: Adult; Alprostadil; Blood Platelets; Cell Adhesion Molecules; Cyclic GMP; Delayed-Action Preparations; Dipyridamole; Female; Humans; In Vitro Techniques; Male; Microfilament Proteins; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Platelet Aggregation Inhibitors; Reference Values; Serotonin; Signal Transduction; Vasodilator Agents	2003
Role of adenosine and nitric oxide on the mechanisms of action of dipyridamole. Stroke, 2005, Volume: 36, Issue:10 Topics: Acetylcholine; Adenosine; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Flow Velocity; Cardiovascular System; Cross-Over Studies; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Models, Biological; Nitric Oxide; Nitroprusside; Phosphoric Diester Hydrolases; Time Factors; Vasodilator Agents	2005

Other Studies

57 other study(ies) available for dipyridamole and cyclic gmp

Article	Year
Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5. Molecular pharmacology, 2003, Volume: 63, Issue:5 Topics: Acrylates; Biological Transport; Cell Division; Cells, Cultured; Humans; Multidrug Resistance-Associated Proteins; Nucleosides; Polymers	2003
Relative potencies of dipyridamole and related agents as inhibitors of cyclic nucleotide phosphodiesterases: possible explanation of mechansim of inhibition of platelet function. Life sciences, 1975, Nov-01, Volume: 17, Issue:9 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Blood Platelets; Cyclic GMP; Dipyridamole; Humans; Mopidamol; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Platelet Adhesiveness; Platelet Aggregation; Pyrimidines	1975
Selective inhibition of separated forms of human platelet cyclic nucleotide phosphodiesterase by platelet aggregation inhibitors. Molecular pharmacology, 1977, Volume: 13, Issue:3 Topics: Adenosine; Blood Platelets; Caffeine; Chromatography, DEAE-Cellulose; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dipyridamole; Humans; In Vitro Techniques; Kinetics; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phthalazines; Platelet Aggregation; Theophylline	1977
Modulation of human leucocyte migration inhibitory factor (LIF) by 3',5'-cyclic AMP, 3',5'-cyclic GMP and agents known to influence intracellular cyclic nucleotide metabolism. Acta pathologica et microbiologica Scandinavica. Section C, Immunology, 1977, Volume: 85, Issue:5 Topics: Bucladesine; Cell Movement; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dipyridamole; Humans; Isoproterenol; Leukocytes; Macrophage Migration-Inhibitory Factors; Norepinephrine; Nucleosides; Nucleotides, Cyclic; Papaverine; Phosphodiesterase Inhibitors	1977
Mode of action of dipyridamole on human platelets. Thrombosis research, 1979, Volume: 16, Issue:3-4 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate; Adenylyl Cyclases; Blood Platelets; Cell Membrane; Cyclic AMP; Cyclic GMP; Dipyridamole; Epinephrine; Epoprostenol; Humans; Malondialdehyde; Platelet Aggregation; Thromboxane B2; Time Factors	1979
Effects of coronary vasodilator on cyclic nucleotides. The concentrations of cyclic AMP and cyclic GMP in canine coronary artery and left ventricular muscle following the administration of various coronary vasodilators. Japanese circulation journal, 1979, Volume: 43 Suppl 1 Topics: Amyl Nitrite; Animals; Coronary Vessels; Cyclic AMP; Cyclic GMP; Diltiazem; Dipyridamole; Dogs; Heart Ventricles; Isosorbide Dinitrate; Myocardium; Nifedipine; Nitroglycerin; Papaverine; Radioimmunoassay; Vasodilator Agents	1979
Cyclic nucleotide phosphodiesterase of normal and leukemic lymphocytes. Kinetic properties and selective alteration of the activity of the multiple molecular forms. Molecular pharmacology, 1979, Volume: 16, Issue:3 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calmodulin; Cyclic GMP; Dipyridamole; In Vitro Techniques; Kinetics; Leukemia; Leukemia L1210; Lymphocytes; Mice; Mice, Inbred DBA; Phosphodiesterase Inhibitors	1979
Effects of intracellular cyclic AMP and cyclic GMP levels on DNA synthesis of young-adult rat hepatocytes in primary culture. Experimental cell research, 1992, Volume: 200, Issue:2 Topics: Age Factors; Animals; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dipyridamole; DNA; In Vitro Techniques; Liver; Male; Rats; Theophylline	1992
Cyclic nucleotide phosphodiesterases from frog atrial fibers: isolation and drug sensitivities. The American journal of physiology, 1992, Volume: 262, Issue:3 Pt 2 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium Chloride; Calmodulin; Chromatography, Ion Exchange; Cyclic GMP; Cytosol; Dipyridamole; Heart Atria; Heart Ventricles; Kinetics; Myocardium; Papaverine; Purinones; Pyrrolidinones; Rana esculenta; Rana ridibunda; Rolipram; Substrate Specificity; Theophylline	1992
A new cGMP phosphodiesterase isolated from bovine platelets is substrate for cAMP- and cGMP-dependent protein kinases: evidence for a key role in the process of platelet activation. Journal of cellular biochemistry, 1991, Volume: 47, Issue:2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Catalysis; Cattle; Chromatography, Affinity; Cyclic AMP; Cyclic GMP; Dipyridamole; Electrophoresis, Polyacrylamide Gel; Kinetics; Phosphorylation; Platelet Activation; Protein Kinases; Purinones; Substrate Specificity	1991
The role of intrarenal adenosine in glomerular action of atrial natriuretic factor. Contributions to nephrology, 1991, Volume: 95 Topics: Adenosine; Adenosine Deaminase; Animals; Atrial Natriuretic Factor; Cyclic GMP; Dipyridamole; Glucagon; Kidney Glomerulus; Male; Rats; Rats, Inbred Strains; Saralasin; Sodium; Theophylline	1991
cGMP-gated conductance in retinal bipolar cells is suppressed by the photoreceptor transmitter. Neuron, 1991, Volume: 7, Issue:4 Topics: Alkaloids; Aminobutyrates; Animals; Cyclic GMP; Dark Adaptation; Dipyridamole; Electric Conductivity; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Light; Neurotransmitter Agents; Phorbol Esters; Photoreceptor Cells; Retina; Staurosporine	1991
cAMP analogs and selective inhibitors used to study low Km Mucor rouxii cAMP phosphodiesterase. The International journal of biochemistry, 1990, Volume: 22, Issue:9 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Centrifugation, Density Gradient; Cyclic AMP; Cyclic GMP; Dipyridamole; Hydrolysis; Mucor; Nicotinic Acids; Papaverine; Pyridazines; Theophylline	1990
Dipyridamole potentiates the anti-aggregating effect of endothelium-derived relaxing factor. Thrombosis research. Supplement, 1990, Volume: 12 Topics: Cyclic AMP; Cyclic GMP; Dipyridamole; Humans; In Vitro Techniques; Nitric Oxide; Platelet Aggregation Inhibitors	1990
Pig aortic endothelial-cell cyclic nucleotide phosphodiesterases. Use of phosphodiesterase inhibitors to evaluate their roles in regulating cyclic nucleotide levels in intact cells. The Biochemical journal, 1990, Feb-15, Volume: 266, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Calcium; Cells, Cultured; Chromatography, Ion Exchange; Colforsin; Cyclic AMP; Cyclic GMP; Dipyridamole; Endothelium, Vascular; Isoquinolines; Kinetics; Purinones; Pyrazines; Pyrrolidinones; Rolipram; Swine; Tetrahydroisoquinolines	1990
Inhibition and stimulation of photoreceptor phosphodiesterases by dipyridamole and M&B 22,948. Molecular pharmacology, 1989, Volume: 36, Issue:5 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Binding Sites; Cattle; Cyclic GMP; Dipyridamole; Enzyme Activation; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Phosphodiesterase Inhibitors; Photoreceptor Cells; Purinones; Rats; Rod Cell Outer Segment; Trypsin	1989
[Effect of adenosine on cyclic nucleotide levels in brain structures]. Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 106, Issue:9 Topics: Adenosine; Animals; Brain; Cerebellum; Cerebral Cortex; Cyclic AMP; Cyclic GMP; Dipyridamole; Hippocampus; Hypothalamus; Male; Rats; Rats, Inbred Strains	1988
Development of tolerance to glyceryl trinitrate in an isolated human peripheral vein and its relation to cyclic GMP metabolism. Acta pharmacologica et toxicologica, 1986, Volume: 59, Issue:2 Topics: Cyclic GMP; Dipyridamole; Drug Tolerance; Guanylate Cyclase; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin	1986
Cyclic GMP binding and phosphodiesterase: implication for platelet function. Advances in cyclic nucleotide and protein phosphorylation research, 1984, Volume: 16 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine Diphosphate; Blood Platelets; Carrier Proteins; Cyclic GMP; Dipyridamole; Humans; Intracellular Signaling Peptides and Proteins; Nitroprusside; Platelet Aggregation; Receptors, Cyclic AMP	1984
Action of adenosine on cyclic 3',5'-nucleotides in glomeruli. The American journal of physiology, 1983, Volume: 244, Issue:6 Topics: Adenosine; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; In Vitro Techniques; Kidney Cortex; Kidney Glomerulus; Kidney Medulla; Kinetics; Rats; Serotonin; Theophylline	1983
Isolation of cyclic nucleotide phosphodiesterase isozymes from pig aorta. Biochemical pharmacology, 1993, Sep-01, Volume: 46, Issue:5 Topics: Animals; Aorta; Calmodulin; Chromatography, Affinity; Cyclic AMP; Cyclic GMP; Dipyridamole; Isoenzymes; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Swine; Vinca Alkaloids	1993
Inhibition of cGMP breakdown promotes the induction of cerebellar long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, May-01, Volume: 16, Issue:9 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cerebellum; Cyclic GMP; Dipyridamole; Long-Term Potentiation; Male; Phosphodiesterase Inhibitors; Purinones; Purkinje Cells; Rats; Rats, Wistar; Synaptic Transmission	1996
Dipyridamole enhances interleukin-1beta-stimulated nitric oxide production by cultured rat vascular smooth muscle cells. European journal of pharmacology, 1996, Feb-05, Volume: 296, Issue:3 Topics: Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dipyridamole; Interleukin-1; Male; Muscle, Smooth, Vascular; Nitric Oxide; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger	1996
Zaprinast, but not dipyridamole, reverses hemodynamic tolerance to nitroglycerin in vivo. European journal of pharmacology, 1996, Oct-10, Volume: 313, Issue:1-2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Analysis of Variance; Animals; Aorta, Abdominal; Blood Pressure; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Drug Tolerance; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Purinones; Rats; Rats, Inbred SHR; Vasodilator Agents	1996
The phosphodiesterase type 4 (PDE4) inhibitor CP-80,633 elevates plasma cyclic AMP levels and decreases tumor necrosis factor-alpha (TNFalpha) production in mice: effect of adrenalectomy. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenalectomy; Animals; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dipyridamole; Epinephrine; Humans; Kinetics; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Monocytes; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piroxicam; Propranolol; Purinones; Pyrimidinones; Thromboxane B2; Time Factors; Tumor Necrosis Factor-alpha; Vinca Alkaloids	1997
Effects of nebulized nitroprusside on pulmonary and systemic hemodynamics during pulmonary hypertension in piglets. Pediatric research, 1998, Volume: 44, Issue:2 Topics: Administration, Inhalation; Aerosols; Animals; Blood Gas Analysis; Cyclic GMP; Dipyridamole; Hemodynamics; Hypertension, Pulmonary; Nitric Oxide; Nitroprusside; Oxygen Consumption; Pulmonary Circulation; Signal Transduction; Swine; Tolazoline; Vasodilation; Vasodilator Agents	1998
Effects of dipyridamole and inhaled nitric oxide in pediatric patients with pulmonary hypertension. American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:5 Pt 1 Topics: Administration, Inhalation; Adolescent; Adult; Aorta; Blood Pressure; Bronchodilator Agents; Cardiac Catheterization; Cardiac Output; Child; Child, Preschool; Cyclic GMP; Dipyridamole; Female; Humans; Hypertension, Pulmonary; Hypoxia; Infant; Male; Nitric Oxide; Phosphodiesterase Inhibitors; Pulmonary Artery; Pulmonary Circulation; Vascular Resistance; Vasodilator Agents	1998
Pulmonary and systemic effects of the phosphodiesterase inhibitor dipyridamole in newborn lambs with persistent pulmonary hypertension. Pediatric research, 1998, Volume: 44, Issue:6 Topics: Animals; Animals, Newborn; Cyclic GMP; Dipyridamole; Disease Models, Animal; Female; Hemodynamics; Humans; In Vitro Techniques; Infant, Newborn; Mesenteric Arteries; Nitric Oxide; Persistent Fetal Circulation Syndrome; Phosphodiesterase Inhibitors; Pregnancy; Pulmonary Artery; Pulmonary Circulation; Sheep	1998
Upregulation of angiotensin converting enzyme by atrial natriuretic peptide and cyclic GMP in human endothelial cells. Cardiovascular research, 1998, Volume: 40, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Humans; Peptidyl-Dipeptidase A; Phosphodiesterase Inhibitors; Protein Kinase Inhibitors; Purinones; Stimulation, Chemical; Thionucleotides; Umbilical Veins; Vasodilator Agents	1998
Determinants of the response of human blood vessels to nitric oxide donors in vivo. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3 Topics: Adult; Bradykinin; Cyclic GMP; Dipyridamole; Forearm; Hand; Humans; Muscle, Smooth, Vascular; Nitric Oxide Donors; Nitroglycerin; Nitroprusside; omega-N-Methylarginine; Radial Artery; Vascular Resistance; Vasodilation; Veins	1999
Novel strategies for opposing murine microglial activation. Neuroscience letters, 2000, Jan-07, Volume: 278, Issue:1-2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Cells, Cultured; Cyclic GMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dipyridamole; Enzyme Inhibitors; Flavonoids; Guanylate Cyclase; Imidazoles; Indazoles; Isoenzymes; Lipopolysaccharides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mice; Microglia; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylcholine; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Signal Transduction; Tumor Necrosis Factor-alpha	2000
ET(A)-receptor blockade and ET(B)-receptor stimulation in experimental congenital diaphragmatic hernia. American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 278, Issue:5 Topics: Acetylcholine; Animals; Antihypertensive Agents; Cyclic GMP; Dipyridamole; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Nitric Oxide; Nitroprusside; Peptides, Cyclic; Phosphodiesterase Inhibitors; Pregnancy; Pulmonary Circulation; Purinones; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Sheep; Vasoconstrictor Agents; Vasodilator Agents; Viper Venoms	2000
beta-Amyloid vasoactivity and proinflammation in microglia can be blocked by cGMP-elevating agents. Annals of the New York Academy of Sciences, 2000, Volume: 903 Topics: Amyloid beta-Peptides; Animals; Aorta; Cyclic GMP; Dipyridamole; Endothelin-1; In Vitro Techniques; Inflammation; Leukotriene B4; Microglia; Muscle, Smooth, Vascular; Nitroprusside; Peptide Fragments; Rats; Vasoconstriction	2000
Effect of dipyridamole and aspirin on the platelet-neutrophil interaction via the nitric oxide pathway. European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1 Topics: Adult; Aspirin; Blood Platelets; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Humans; Male; Neutrophils; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors	2000
Treatment of pulmonary hypertension during surgery with nitric oxide and vasodilators. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2000, Volume: 47, Issue:6 Topics: Administration, Inhalation; Colectomy; Cyclic GMP; Dipyridamole; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Middle Aged; Nitric Oxide; Nitroglycerin; Vasodilator Agents	2000
Cyclic GMP is a second messenger by which nitric oxide inhibits diaphragm contraction. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 1998, Volume: 119, Issue:1 Topics: Aminoquinolines; Animals; Cyclic GMP; Diaphragm; Dipyridamole; Enzyme Inhibitors; Guanylate Cyclase; Male; Muscle Contraction; Nitric Oxide; Nitroarginine; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Second Messenger Systems	1998
The role of cGMP hydrolysing phosphodiesterases 1 and 5 in cerebral artery dilatation. European journal of pharmacology, 2001, May-18, Volume: 420, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Basilar Artery; Cerebral Arteries; Cyclic AMP; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; In Vitro Techniques; Isoenzymes; Male; Milrinone; Nitroprusside; Oxadiazoles; Pentoxifylline; Phosphodiesterase Inhibitors; Purinones; Quinoxalines; Vasodilation; Vasodilator Agents	2001
Ibudilast attenuates astrocyte apoptosis via cyclic GMP signalling pathway in an in vitro reperfusion model. British journal of pharmacology, 2001, Volume: 133, Issue:6 Topics: Alkaloids; Animals; Animals, Newborn; Apoptosis; Astrocytes; Carbazoles; Cell Survival; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytochrome c Group; Dipyridamole; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; Indoles; Mitochondria; Pentoxifylline; Peptide Hydrolases; Phosphodiesterase Inhibitors; Purinones; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Theophylline; Vinca Alkaloids	2001
Urodilatin, a natriuretic peptide stimulating particulate guanylate cyclase, and the phosphodiesterase 5 inhibitor dipyridamole attenuate experimental pulmonary hypertension: synergism upon coapplication. American journal of respiratory cell and molecular biology, 2001, Volume: 25, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Dipyridamole; Disease Models, Animal; Drug Synergism; Guanylate Cyclase; Hypertension, Pulmonary; Infusions, Intravenous; Peptide Fragments; Phosphodiesterase Inhibitors; Pulmonary Artery; Pulmonary Circulation; Rabbits	2001
Homogeneous segmental profile of carbon monoxide-mediated pulmonary vasodilation in rats. American journal of physiology. Lung cellular and molecular physiology, 2001, Volume: 281, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbon Monoxide; Cyclic GMP; Dipyridamole; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Hypertension, Pulmonary; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Oxadiazoles; Peptides; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Pulmonary Circulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vascular Resistance; Vasodilation	2001
cGMP abolishes agonist-induced [Ca(2+)](i) oscillations in human bladder epithelial cells. American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:6 Topics: Acetylcholine; Alkaloids; Bradykinin; Calcium Signaling; Calcium-Transporting ATPases; Carbazoles; Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dipyridamole; Drug Antagonism; Enzyme Inhibitors; Epithelial Cells; Humans; Indoles; Kinetics; Macrocyclic Compounds; Oxazoles; Phosphodiesterase Inhibitors; Urinary Bladder	2001
Intravenous dipyridamole enhances the effects of inhaled nitric oxide and prevents rebound pulmonary hypertension in piglets. Pediatric research, 2002, Volume: 52, Issue:5 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Inhalation; Animals; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dipyridamole; Drug Synergism; Hypertension, Pulmonary; Injections, Intravenous; Nitric Oxide; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Recurrence; Substance Withdrawal Syndrome; Swine; Vascular Resistance	2002
Effect of combination therapy with dipyridamole and quinapril in diabetic nephropathy. Diabetes research and clinical practice, 2003, Volume: 59, Issue:2 Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blotting, Western; Creatinine; Cyclic GMP; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dipyridamole; Drug Therapy, Combination; Female; Immunohistochemistry; Isoquinolines; Kidney; Lipid Peroxides; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Phosphodiesterase Inhibitors; Phosphoproteins; Quinapril; Random Allocation; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines	2003
Role of cyclic nucleotides in regulation of pulmonary artery tone in rabbits. Bulletin of experimental biology and medicine, 2003, Volume: 135, Issue:6 Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Pulmonary Artery; Rabbits; Signal Transduction; Sympathomimetics; Theophylline; Vasodilator Agents	2003
Intermittent nitric oxide combined with intravenous dipyridamole in a piglet model of acute pulmonary hypertension. Anesthesia and analgesia, 2003, Volume: 97, Issue:5 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthesia; Animals; Blood Pressure; Cardiac Output; Central Venous Pressure; Cyclic GMP; Dipyridamole; Hemodynamics; Hypertension, Pulmonary; Injections, Intravenous; Nitric Oxide; Pulmonary Artery; Swine; Vasoconstrictor Agents; Vasodilator Agents	2003
Lack of cyclic nucleotide regulation of MBCQ-induced relaxation of rat ileal smooth muscle. Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2003, Volume: 39, Issue:3 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Carbachol; Cholinergic Agonists; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dipyridamole; Ileum; Male; Muscle Relaxation; Muscle, Smooth; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Potassium; Purinones; Quinazolines; Rats; Rats, Wistar	2003
The actions of sodium nitroprusside and the phosphodiesterase inhibitor dipyridamole on phasic activity in the isolated guinea-pig bladder. BJU international, 2004, Volume: 93, Issue:6 Topics: Animals; Cyclic GMP; Dipyridamole; Female; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Nitric Oxide Donors; Nitroprusside; Phosphodiesterase Inhibitors; Pressure; Urinary Bladder	2004
Postnatal maturation of phosphodiesterase 5 (PDE5) in piglet pulmonary arteries: activity, expression, effects of PDE5 inhibitors, and role of the nitric oxide/cyclic GMP pathway. Pediatric research, 2004, Volume: 56, Issue:4 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Animals, Newborn; Blotting, Western; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dipyridamole; In Vitro Techniques; Male; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Artery; Purines; Purinones; Sildenafil Citrate; Sulfones; Swine; Vasodilation; Vasodilator Agents	2004
Cyclic nucleotides and neuroblastoma differentiation. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Neuroblastoma; Nucleotides, Cyclic; Phosphodiesterase Inhibitors; Phthalazines; Purinones; Time Factors	2004
Mechanism of dipyridamole's action in inhibition of venous and arterial smooth muscle cell proliferation. Basic & clinical pharmacology & toxicology, 2006, Volume: 99, Issue:6 Topics: Aorta; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dipyridamole; Enzyme Inhibitors; Graft Occlusion, Vascular; Humans; L-Lactate Dehydrogenase; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Saphenous Vein; Thionucleotides	2006
Involvement of cyclic GMP in phytochrome-controlled flowering of Pharbitis nil. Journal of plant physiology, 2008, May-26, Volume: 165, Issue:8 Topics: 1-Methyl-3-isobutylxanthine; Cotyledon; Cyclic GMP; Dipyridamole; Flowers; Ipomoea nil; Light; Nitroprusside; Photoperiod; Phytochrome	2008
PDE4 and PDE5 regulate cyclic nucleotides relaxing effects in human umbilical arteries. European journal of pharmacology, 2008, Mar-17, Volume: 582, Issue:1-3 Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Colforsin; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Dipyridamole; Female; Guanylate Cyclase; Histamine; Humans; In Vitro Techniques; Isoenzymes; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthyridines; Nitroprusside; Phosphodiesterase 4 Inhibitors; Phosphodiesterase 5 Inhibitors; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Rolipram; Serotonin; Umbilical Arteries; Vasodilator Agents	2008
Dipyridamole synergizes with nitric oxide to prolong inhibition of thrombin-induced platelet shape change. Platelets, 2011, Volume: 22, Issue:1 Topics: Blood Platelets; Cell Adhesion Molecules; Cell Shape; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 5; Dipyridamole; Drug Synergism; Humans; Microfilament Proteins; Models, Molecular; Nitric Oxide; Nitroprusside; Phosphodiesterase Inhibitors; Phosphoproteins; Phosphorylation; Platelet Aggregation; Stroke; Thrombin	2011
Dipyridamole decreases inflammatory metalloproteinase-9 expression and release by human monocytes. Thrombosis and haemostasis, 2013, Volume: 109, Issue:2 Topics: Anti-Inflammatory Agents; Cyclic AMP; Cyclic GMP; Dipyridamole; Dose-Response Relationship, Drug; Down-Regulation; Humans; I-kappa B Proteins; Inflammation Mediators; Matrix Metalloproteinase 9; Monocytes; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; RNA, Messenger; Signal Transduction; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Transcription Factor AP-1; Transcription Factor RelA; Tumor Necrosis Factor-alpha; U937 Cells	2013
Antiplatelet effect of AMP-activated protein kinase activator and its potentiation by the phosphodiesterase inhibitor dipyridamole. Biochemical pharmacology, 2013, Oct-01, Volume: 86, Issue:7 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cyclic GMP; Dipyridamole; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Male; Nitric Oxide Synthase Type III; Phosphodiesterase Inhibitors; Phosphorylation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Ribonucleotides; Signal Transduction; Thrombosis	2013
Modulation of high affinity ATP-dependent cyclic nucleotide transporters by specific and non-specific cyclic nucleotide phosphodiesterase inhibitors. European journal of pharmacology, 2014, Dec-15, Volume: 745 Topics: ATP-Binding Cassette Transporters; Caffeine; Carbolines; Cyclic AMP; Cyclic GMP; Dipyridamole; Humans; Imidazoles; Kinetics; Multidrug Resistance-Associated Proteins; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purinones; Sulfones; Tadalafil; Theophylline; Triazines; Vardenafil Dihydrochloride	2014
Influence of nitric oxide and phosphodiesterases during in vitro maturation of bovine oocytes on meiotic resumption and embryo production. Zygote (Cambridge, England), 2017, Volume: 25, Issue:3 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blastocyst; Cattle; Cyclic AMP; Cyclic GMP; Dipyridamole; Female; Fertilization in Vitro; In Vitro Oocyte Maturation Techniques; Male; Meiosis; Nitric Oxide; Nitric Oxide Donors; Oocytes; Phosphodiesterase Inhibitors; Quinolones; S-Nitroso-N-Acetylpenicillamine; Sildenafil Citrate	2017