Page last updated: 2024-08-26

diprotin a and endomorphin 2

diprotin a has been researched along with endomorphin 2 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's6 (75.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erdö, F; Fürst, S; Gyarmati, Z; Makó, E; Orosz, G; Rónai, AZ; Székely, JI; Timár, J; Tóth, G1
Hayashi, T; Katsuyama, S; Sakurada, C; Sakurada, S; Sakurada, T; Tan-No, K1
Sakurada, C1
Bagosi, Z; Bujdosó, E; Jászberényi, M; Szabó, G; Telegdy, G1
Bagosi, Z; Jászberényi, M; Telegdy, G1
Barna, I; Darula, Z; Kató, E; Király, K; Prohászka, Z; Rónai, AZ; Szalay, B; Szebeni, A; Szemenyei, E; Till, I; Tóth, G1
Barna, I; Gyires, K; Király, K; Rónai, AZ; Szalai, J; Szalay, B; Verbeken, M1
Cravezic, A; do-Rego, JC; Fichna, J; Gach, K; Janecka, A; Perlikowska, R; Storr, MA1

Reviews

1 review(s) available for diprotin a and endomorphin 2

ArticleYear
[Development of a new analgesic based on metabolism of endomorphin, an endogenous opioid peptide].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2004, Volume: 124, Issue:8

    Topics: Analgesics; Animals; Brain; Dipeptidyl Peptidase 4; Drug Design; Humans; Mice; Oligopeptides; Synaptic Membranes

2004

Other Studies

7 other study(ies) available for diprotin a and endomorphin 2

ArticleYear
Diprotin A, an inhibitor of dipeptidyl aminopeptidase IV(EC 3.4.14.5) produces naloxone-reversible analgesia in rats.
    Life sciences, 1999, Volume: 64, Issue:2

    Topics: Analgesia; Analgesics, Opioid; Animals; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dose-Response Relationship, Drug; Drug Synergism; Endorphins; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle, Smooth; Naloxone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Wistar

1999
Degradation of endomorphin-2 at the supraspinal level in mice is initiated by dipeptidyl peptidase IV: an in vitro and in vivo study.
    Biochemical pharmacology, 2003, Aug-15, Volume: 66, Issue:4

    Topics: Aminopeptidases; Analgesics, Opioid; Animals; Brain; Dipeptidyl Peptidase 4; Male; Mice; Oligopeptides; Spinal Cord; Synaptic Membranes

2003
The effects of endomorphins and diprotin A on striatal dopamine release induced by electrical stimulation-an in vitro superfusion study in rats.
    Neurochemistry international, 2006, Volume: 49, Issue:7

    Topics: Animals; Corpus Striatum; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Dopamine; Electric Stimulation; Infusion Pumps; Male; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; Oligopeptides; Organ Culture Techniques; Presynaptic Terminals; Radioligand Assay; Rats; Rats, Wistar; Substantia Nigra; Synaptic Transmission

2006
The effects of endomorphins on striatal [3H]GABA release induced by electrical stimulation: an in vitro superfusion study in rats.
    Neurochemical research, 2009, Volume: 34, Issue:5

    Topics: Animals; Corpus Striatum; Dipeptidyl-Peptidase IV Inhibitors; Electric Stimulation; gamma-Aminobutyric Acid; Male; Naloxone; Naltrexone; Oligopeptides; Perfusion; Rats; Rats, Wistar; Receptors, Opioid, mu; Tritium

2009
Immunoreactive endomorphin 2 is generated extracellularly in rat isolated L4,5 dorsal root ganglia by DPP-IV.
    Regulatory peptides, 2009, Oct-09, Volume: 157, Issue:1-3

    Topics: Animals; Cell Membrane; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Ganglia, Spinal; Oligopeptides; Pilot Projects; Rats

2009
Intrathecally injected Ile-Pro-Ile, an inhibitor of membrane ectoenzyme dipeptidyl peptidase IV, is antihyperalgesic in rats by switching the enzyme from hydrolase to synthase functional mode to generate endomorphin 2.
    European journal of pharmacology, 2009, Oct-12, Volume: 620, Issue:1-3

    Topics: Animals; Carrageenan; Cell Membrane; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Hyperalgesia; Injections, Spinal; Ligases; Male; Oligopeptides; Rats; Rats, Wistar

2009
The novel endomorphin degradation blockers Tyr-Pro-DClPhe-Phe-NH (EMDB-1) and Tyr-Pro-Ala-NH (EMDB-2) prolong endomorphin-2 action in rat ileum in vitro.
    Chemical biology & drug design, 2010, Volume: 76, Issue:1

    Topics: Amino Acid Sequence; Animals; Hydroxamic Acids; Ileum; Oligopeptides; Rats

2010