dipropylenetriamine-nonoate and 2-2--(hydroxynitrosohydrazono)bis-ethanamine

dipropylenetriamine-nonoate has been researched along with 2-2--(hydroxynitrosohydrazono)bis-ethanamine* in 2 studies

Other Studies

2 other study(ies) available for dipropylenetriamine-nonoate and 2-2--(hydroxynitrosohydrazono)bis-ethanamine

Article	Year
Mechanistic studies on the reaction between R2N-NONOates and aquacobalamin: evidence for direct transfer of a nitroxyl group from R2N-NONOates to cobalt(III) centers. Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:47 Topics: Alkenes; Catalysis; Cobalt; Hydrazines; Kinetics; Magnetic Resonance Spectroscopy; Nitric Oxide Donors; Nitrogen Oxides; Nitroso Compounds; Spectrophotometry, Ultraviolet; Vitamin B 12	2009
Two aerosolized nitric oxide adducts as selective pulmonary vasodilators for acute pulmonary hypertension. Chest, 2003, Volume: 123, Issue:3 To determine the selective vasodilatory effects of two inhaled "NONOate" aerosols in a closed chest pig model of acute pulmonary hypertension (APH).. APH was induced by IV infusion of the prostaglandin H(2)/thromboxane A(2) receptor agonist (U46619). Aerosolized diethylenetriamine nitric oxide (NO) adduct (DETA/NO, n = 4), dipropylenetriamine NO adduct (DPTA/NO, n = 4) [60 micro mol each], or placebo (n = 4) was delivered via the trachea. Hemodynamic parameters and blood samples were measured before and after inhalation therapy.. Compared to control animals, pulmonary vascular resistance and pulmonary arterial pressure were significantly reduced from 10 to 105 min after DETA/NO administration and from 10 to 45 min after DPTA/NO aerosol administration (p < 0.05). Both aerosols had no significant effect on systemic vascular resistance or systemic BP. Serum nitrite significantly increased after the inhalation of both NONOates (p < 0.01). There was a tendency for reduced intrapulmonary shunting, particularly after treatment with DETA/NO.. Both DETA/NO and DPTA/NO administered as aerosols selectively reduced pulmonary hypertension induced by U46619. Topics: Aerosols; Alkenes; Analysis of Variance; Animals; Female; Hemodynamics; Hypertension, Pulmonary; Nitric Oxide Donors; Nitroso Compounds; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Swine; Vasodilator Agents	2003

Article

Year

Mechanistic studies on the reaction between R2N-NONOates and aquacobalamin: evidence for direct transfer of a nitroxyl group from R2N-NONOates to cobalt(III) centers.

Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:47

Topics: Alkenes; Catalysis; Cobalt; Hydrazines; Kinetics; Magnetic Resonance Spectroscopy; Nitric Oxide Donors; Nitrogen Oxides; Nitroso Compounds; Spectrophotometry, Ultraviolet; Vitamin B 12

2009

Two aerosolized nitric oxide adducts as selective pulmonary vasodilators for acute pulmonary hypertension.

Chest, 2003, Volume: 123, Issue:3

To determine the selective vasodilatory effects of two inhaled "NONOate" aerosols in a closed chest pig model of acute pulmonary hypertension (APH).. APH was induced by IV infusion of the prostaglandin H(2)/thromboxane A(2) receptor agonist (U46619). Aerosolized diethylenetriamine nitric oxide (NO) adduct (DETA/NO, n = 4), dipropylenetriamine NO adduct (DPTA/NO, n = 4) [60 micro mol each], or placebo (n = 4) was delivered via the trachea. Hemodynamic parameters and blood samples were measured before and after inhalation therapy.. Compared to control animals, pulmonary vascular resistance and pulmonary arterial pressure were significantly reduced from 10 to 105 min after DETA/NO administration and from 10 to 45 min after DPTA/NO aerosol administration (p < 0.05). Both aerosols had no significant effect on systemic vascular resistance or systemic BP. Serum nitrite significantly increased after the inhalation of both NONOates (p < 0.01). There was a tendency for reduced intrapulmonary shunting, particularly after treatment with DETA/NO.. Both DETA/NO and DPTA/NO administered as aerosols selectively reduced pulmonary hypertension induced by U46619.

Topics: Aerosols; Alkenes; Analysis of Variance; Animals; Female; Hemodynamics; Hypertension, Pulmonary; Nitric Oxide Donors; Nitroso Compounds; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Swine; Vasodilator Agents

2003