Page last updated: 2024-08-25

diprafenone and propranolol

diprafenone has been researched along with propranolol in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19902 (33.33)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Cantor, E; Greenberg, S; Paul, J1
Jähnchen, E; Trenk, D; Wagner, F1
Barr, WH; Dee, CM; Duerr, H; Hinderling, PH; Seiberling, M; Tendolkar, A1

Trials

2 trial(s) available for diprafenone and propranolol

ArticleYear
Evaluation of the beta-adrenoceptor blocking activity of the Class Ic antiarrhythmic drug diprafenone in man.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Isoproterenol; Male; Propafenone; Propranolol; Random Allocation

1989
Single-dose interaction study of diprafenone HCl and propranolol HCl in healthy volunteers.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:7

    Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Drug Administration Schedule; Drug Combinations; Drug Interactions; Electrocardiography; Exercise Test; Half-Life; Heart Rate; Humans; Male; Propafenone; Propranolol; Rest; Sensitivity and Specificity

1995

Other Studies

4 other study(ies) available for diprafenone and propranolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Beta-adrenoceptor blocking activity of diprafenone in anesthetized dogs: comparison with propafenone and propranolol.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Anti-Arrhythmia Agents; Dihydroalprenolol; Dogs; Female; Heart; Isoproterenol; Male; Membranes; Myocardium; Propafenone; Propranolol; Receptors, Adrenergic, beta

1989