diphenylamine has been researched along with u 0126 in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alexopoulos, LG; Cosgrove, BD; Griffith, LG; Hang, TC; Hendriks, BS; Lauffenburger, DA; Sorger, PK | 1 |
| Boni, A; Cogdill, AP; Dang, P; Ferrone, CR; Fisher, DE; Flaherty, KT; Lawrence, DP; Njauw, CN; Sloss, CM; Tsao, H; Udayakumar, D; Wargo, JA | 1 |
| Hesson, T; Le, HV; Liu, Y; Liu, YH; Mayhood, TW; Sheth, PR; Vilenchik, L; Zhao, J | 1 |
| Huber, M; Marschall, JS; Schuh, W; Wilhelm, T | 1 |
| Hantani, Y; Kakegawa, J; Nakamura, M; Okajima, N; Sakai, T; Watanabe, Y; Yamaguchi, T; Yoshida, T | 1 |
| Albanesi, JP; Barylko, B; Cobb, MH; Guerra, ML; Wauson, EM | 1 |
| Chen, Y; Dong, J; Ji, M; Kremerskothen, J; Wennmann, DO; Yang, S; Zhang, L | 1 |
| Du, J; Liu, Q; Ni, Y; Pang, Z; Wang, L; Zhang, J | 1 |
| Imoto, M; Kiga, M; Murakami, R; Nakanishi, T; Nakayama, A; Sasazawa, Y; Shikata, Y; Tashiro, E | 1 |
9 other study(ies) available for diphenylamine and u 0126
| Article | Year |
|---|---|
Cytokine-associated drug toxicity in human hepatocytes is associated with signaling network dysregulation.
Topics: Anti-Infective Agents; Benzamides; Butadienes; Caspases; Cell Survival; Cells, Cultured; Clarithromycin; Cytokines; Diphenylamine; Fluoroquinolones; Hepatocytes; Humans; Mitogen-Activated Protein Kinases; Models, Biological; Naphthyridines; Nitriles; Phosphoproteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Time Factors | 2010 |
Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function.
Topics: Antigens, Neoplasm; Benzamides; Butadienes; Cell Line, Tumor; Combined Modality Therapy; Diphenylamine; Epitopes, T-Lymphocyte; Extracellular Signal-Regulated MAP Kinases; gp100 Melanoma Antigen; Humans; Intramolecular Oxidoreductases; MAP Kinase Signaling System; MART-1 Antigen; Melanoma; Membrane Glycoproteins; Neoplasm Proteins; Nitriles; Oxidoreductases; Proto-Oncogene Proteins B-raf; T-Lymphocytes | 2010 |
Fully activated MEK1 exhibits compromised affinity for binding of allosteric inhibitors U0126 and PD0325901.
Topics: Allosteric Regulation; Animals; Benzamides; Butadienes; Cell Line; Diphenylamine; Enzyme Activation; Insecta; Mitogen-Activated Protein Kinase 1; Nitriles; Protein Binding; Protein Kinase Inhibitors | 2011 |
MEK/Erk-based negative feedback mechanism involved in control of Steel Factor-triggered production of Krüppel-like factor 2 in mast cells.
Topics: Animals; Benzamides; Butadienes; Cells, Cultured; Diphenylamine; Gene Expression Regulation; Hypolipidemic Agents; Insulin-Like Growth Factor I; Interleukin-6; Kruppel-Like Transcription Factors; Lipopolysaccharides; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mast Cells; Mice; Nitriles; Phosphatidylinositol 3-Kinase; Protein Kinase Inhibitors; Signal Transduction; Simvastatin; Stem Cell Factor; Thapsigargin; Tumor Necrosis Factor-alpha | 2012 |
Identification and characterization of a novel chemotype MEK inhibitor able to alter the phosphorylation state of MEK1/2.
Topics: Allosteric Regulation; Antineoplastic Agents; Benzamides; Butadienes; Chromatography, Affinity; Diphenylamine; Dose-Response Relationship, Drug; HEK293 Cells; HT29 Cells; Humans; Kinetics; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Molecular Structure; Molecular Targeted Therapy; Neoplasms; Nitriles; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Pyridones; Pyrimidinones; Signal Transduction | 2012 |
Off-target effects of MEK inhibitors.
Topics: Animals; Benzamides; Butadienes; Calcium; Cell Line; Chromaffin Cells; Diphenylamine; Epinephrine; Flavonoids; Insulin; Insulin Secretion; Insulin-Secreting Cells; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mitogen-Activated Protein Kinase 3; Nitriles; Protein Kinase Inhibitors | 2013 |
Phosphorylation of KIBRA by the extracellular signal-regulated kinase (ERK)-ribosomal S6 kinase (RSK) cascade modulates cell proliferation and migration.
Topics: Animals; Benzamides; Butadienes; Cell Line, Tumor; Cell Movement; Cell Proliferation; Diphenylamine; Enzyme Inhibitors; HEK293 Cells; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; MCF-7 Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Nitriles; Phosphoproteins; Phosphorylation; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction | 2014 |
PKD1 is downregulated in non-small cell lung cancer and mediates the feedback inhibition of mTORC1-S6K1 axis in response to phorbol ester.
Topics: Aminopyridines; Benzamides; Blotting, Western; Butadienes; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromones; Diphenylamine; Enzyme Activation; Humans; Mechanistic Target of Rapamycin Complex 1; Morpholines; Multiprotein Complexes; Nitriles; Phorbol Esters; Real-Time Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases; TRPP Cation Channels | 2015 |
SMK-17, a MEK1/2-specific inhibitor, selectively induces apoptosis in β-catenin-mutated tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; beta Catenin; Butadienes; Cell Line, Tumor; Cell Proliferation; Diphenylamine; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Neoplasms; Nitriles; Protein Kinase Inhibitors; Sulfonamides; Transcription Factor 7-Like 2 Protein; Transcription, Genetic | 2015 |