diphenoxylate has been researched along with loperamide in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (60.42) | 18.7374 |
| 1990's | 7 (14.58) | 18.2507 |
| 2000's | 5 (10.42) | 29.6817 |
| 2010's | 6 (12.50) | 24.3611 |
| 2020's | 1 (2.08) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Heap, J | 1 |
| Jaffé, G | 1 |
| Amery, W; Lange, AP; Secher, NJ | 1 |
| Pietrusko, RG | 1 |
| Heykants, JJ; Janssen, PA; McGuire, JL; Niemegeers, CJ | 1 |
| Bianchi, C; Goi, A | 1 |
| Alioto, RL; Eash, JR; Krebs, JB; Mir, GN; Sperow, JW; Yelnosky, J | 1 |
| Steffen, R | 1 |
| Govaerts-Lepicard, M | 1 |
| Awouters, F; Mcguire, JL; Niemegeers, CJ | 1 |
| Pelemans, W; Vantrappen, F | 1 |
| Ahmad, SR | 1 |
| Coupar, IM | 2 |
| Schiller, LR | 1 |
| Lange, AP; Moth, I; Osler, M; Thomsen Pedersen, G; Westergaard, JG | 1 |
| Sommers, DK; Steyn, AG; Van Wyk, M | 1 |
| Jackson, TE; Limp, GL; Yellin, TO; Zavecz, JH | 1 |
| Awouters, F; Janssen, PA; Niemegeers, CJ | 1 |
| Bondarev, IuA; Nikitin, AM | 1 |
| Obel, AO | 1 |
| Robertson, HD | 1 |
| Bergman, L; Djärv, L | 1 |
| Andersen, B; Gudmand-Høyer, E; Skovbjerg, H; Wille-Jørgensen, P | 1 |
| Abbey, DM; Knoop, FC | 1 |
| Pounder, RE; Shee, CD | 1 |
| Corbett, CL; Holdsworth, CD; Palmer, KR | 1 |
| Alioto, RL; Mir, GN | 1 |
| Aillaud, L; Barinagarrementería, R; Landa, L; Ramírez-Degollado, J | 1 |
| Faacks, N; Kasahara, M; Shelton, D | 1 |
| Barragan, RF; Garcia Compean, D; Guzman de la Garza, F; Maldonado, H; Michel, H; Ramos Jimenez, J; Saenz, C | 1 |
| Coupar, IM; De Luca, A; Murray, G | 1 |
| Andree, G; Kuster, GG | 1 |
| Coupar, IM; De Luca, A | 1 |
| Crowe, A; Wong, P | 1 |
| Ippoliti, C; Stern, J | 1 |
| Camporota, L; Dunckley, P; Frenz, MB; Jewell, DP; Travis, SP | 1 |
| Birkenfeld, G | 1 |
| Sökeland, J | 1 |
| Griffin, PM; Jones, TF; Nelson, JM; Scallan, E; Smith, KE | 1 |
| Meißner, W; Pastrana, T | 1 |
| Allen, LA; Ambardekar, AV; Jurgens, PT; McIlvennan, CK | 1 |
| Friedenberg, FK; Piech, G; Reichenbach, ZW; Selby, A | 1 |
| Bhattacharya, B; Bugaev, N; Chiu, WC; Como, JJ; Cripps, MW; Ferrada, P; Gelbard, RB; Gondek, S; Kasotakis, G; Kim, D; Mentzer, C; Robinson, BRH; Salcedo, ES; Yeh, DD | 1 |
| Haigney, MCP; Kao, DP; Kleiman, RB; Klein, M; Krantz, MJ; Rudo, TJ; Stockbridge, N | 1 |
11 review(s) available for diphenoxylate and loperamide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacotherapy of diarrhea.
Topics: Antidiarrheals; Cholera; Cholestyramine Resin; Colon; Diarrhea; Diphenoxylate; Fluid Therapy; Giardiasis; Humans; Intestinal Mucosa; Kaolin; Lactobacillus; Loperamide; Opium; Osmosis; Parasympatholytics; Peristalsis; Prostaglandin Antagonists; Salmonella Infections; Stomach | 1979 |
Opioid action of the intestine: the importance of the intestinal mucosa.
Topics: Antidiarrheals; Body Water; Diarrhea; Diphenoxylate; Humans; Intestinal Mucosa; Intestines; Loperamide; Muscle, Smooth; Narcotics; Norepinephrine; Opioid-Related Disorders; Receptors, Opioid; Substance Withdrawal Syndrome | 1987 |
Faecal incontinence.
Topics: Atropine; Biofeedback, Psychology; Diphenoxylate; Drug Combinations; Electromyography; Fecal Incontinence; Humans; Loperamide; Manometry; Radiography; Rectum | 1986 |
Pharmacology of antidiarrheal drugs.
Topics: Animals; Antidiarrheals; Biological Transport; Body Fluids; Castor Oil; Diarrhea; Diphenoxylate; Electrolytes; Gastrointestinal Motility; Humans; Ileum; Intestinal Mucosa; Kinetics; Loperamide; Morphine; Narcotics; Peristalsis; Receptors, Opioid | 1983 |
[Problems with ileostomies (review of the literature)].
Topics: Atropine; Cicatrix; Codeine; Constriction, Pathologic; Diet; Diphenoxylate; Drug Combinations; Gastrointestinal Motility; Humans; Ileostomy; Intestinal Diseases; Loperamide; Magnetics; Peristalsis; Postoperative Complications; Rehabilitation, Vocational; Social Adjustment; Water-Electrolyte Imbalance | 1984 |
Management of acute cancer treatment-induced diarrhea.
Topics: Antidiarrheals; Antineoplastic Combined Chemotherapy Protocols; Atropine; Diarrhea; Diphenoxylate; Humans; Loperamide; Neoplasms; Nurse-Patient Relations; Nurse's Role; Nursing Assessment; Nursing Methodology Research; Octreotide; Oncology Nursing; Quality of Life | 2003 |
[Treating travelers' diarrhea. When should medication be given?].
Topics: Adult; Anti-Bacterial Agents; Atropine; Bismuth; Child; Cross-Sectional Studies; Diphenoxylate; Drug Combinations; Dysentery; Fluid Therapy; Fluoroquinolones; Humans; Loperamide; Organometallic Compounds; Probiotics; Risk Factors; Salicylates; Travel | 2007 |
[Treatment of diarrhea with loperamide in palliative medicine. A systematic review].
Topics: Acquired Immunodeficiency Syndrome; Antidiarrheals; Controlled Clinical Trials as Topic; Diarrhea; Diphenoxylate; Drug Therapy, Combination; Humans; Loperamide; Octreotide; Palliative Care; Thiorphan | 2013 |
Pathophysiology, Differential Diagnosis, and Treatment of Diabetic Diarrhea.
Topics: Antidiarrheals; Autonomic Nervous System Diseases; Blind Loop Syndrome; Celiac Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diagnosis, Differential; Diarrhea; Diphenoxylate; Enteric Nervous System; Exocrine Pancreatic Insufficiency; Gastrointestinal Agents; Gastrointestinal Motility; Hypoglycemic Agents; Imidazoles; Inflammation; Inflammatory Bowel Diseases; Interstitial Cells of Cajal; Intestinal Absorption; Intestinal Mucosa; Irritable Bowel Syndrome; Loperamide; Neuroglia; Non-Nutritive Sweeteners; Oxidative Stress; Phenylalanine; Serotonin 5-HT3 Receptor Antagonists | 2019 |
Antimotility agents for the treatment of acute noninfectious diarrhea in critically ill patients: A practice management guideline from the Eastern Association for the Surgery of Trauma.
Topics: Adult; Antidiarrheals; Critical Illness; Diarrhea; Diet Therapy; Diphenoxylate; Gastrointestinal Motility; Humans; Loperamide; Randomized Controlled Trials as Topic; Treatment Outcome | 2019 |
10 trial(s) available for diphenoxylate and loperamide
| Article | Year |
|---|---|
A comparison of lomotil and imodium in acute non-specific diarrhoea.
Topics: Acute Disease; Adult; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Female; Humans; Isonipecotic Acids; Loperamide; Male; Piperidines | 1977 |
Loperamide for diarrhea.
Topics: Adult; Biopharmaceutics; Child, Preschool; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Double-Blind Method; Female; Humans; Loperamide; Male; Piperidines; Placebos; Pregnancy | 1977 |
Prostaglandin-induced diarrhoea treated with loperamide or diphenoxylate. A double-blind study.
Topics: Abortion, Induced; Adult; Blood Pressure; Body Temperature; Capsules; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Double-Blind Method; Female; Heart Rate; Humans; Isonipecotic Acids; Loperamide; Piperidines; Placebos; Prostaglandins; Respiration; Time Factors | 1977 |
Multicentre general practice comparison of loperamide and diphenoxylate with atropine in the treatment of acute diarrhoea in adults.
Topics: Acute Disease; Adolescent; Adult; Atropine; Diarrhea; Diphenoxylate; Drug Therapy, Combination; Humans; Isonipecotic Acids; Loperamide; Piperidines | 1979 |
A double blind crossover comparison of loperamide with diphenoxylate in the symptomatic treatment of chronic diarrhea.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Feces; Female; Humans; Isonipecotic Acids; Loperamide; Male; Middle Aged; Piperidines | 1976 |
A comparative study of loperamide and diphenoxylate in the treatment of chronic diarrhoea caused by intestinal resection.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Crohn Disease; Diarrhea; Diphenoxylate; Double-Blind Method; Female; Humans; Intestines; Isonipecotic Acids; Loperamide; Male; Middle Aged; Piperidines; Postoperative Complications; Random Allocation | 1981 |
Diarrhoea following jejuno-ileostomy for morbid obesity. A randomised trial of loperamide and diphenoxylate.
Topics: Adult; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Female; Humans; Ileum; Isonipecotic Acids; Jejunum; Loperamide; Male; Obesity; Piperidines; Postoperative Complications; Random Allocation | 1982 |
Loperamide, diphenoxylate, and codeine phosphate in chronic diarrhoea.
Topics: Chronic Disease; Clinical Trials as Topic; Codeine; Diarrhea; Diphenoxylate; Double-Blind Method; Humans; Isonipecotic Acids; Loperamide; Piperidines | 1980 |
Double-blind cross-over study comparing loperamide, codeine and diphenoxylate in the treatment of chronic diarrhea.
Topics: Antidiarrheals; Chronic Disease; Clinical Trials as Topic; Codeine; Diarrhea; Diphenoxylate; Double-Blind Method; Humans; Isonipecotic Acids; Loperamide; Piperidines; Random Allocation; Time Factors | 1980 |
Octreotide therapy of large-volume refractory AIDS-associated diarrhea: a randomized controlled trial.
Topics: Acquired Immunodeficiency Syndrome; Adult; Age of Onset; Diarrhea; Diphenoxylate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Loperamide; Male; Middle Aged; Octreotide; Placebos; Time Factors | 1994 |
27 other study(ies) available for diphenoxylate and loperamide
| Article | Year |
|---|---|
Loperamide and acute infective diarrhoea in children.
Topics: Acute Disease; Child; Child, Preschool; Diarrhea; Diphenoxylate; Dysentery, Bacillary; Humans; Infant; Loperamide; Piperidines | 1979 |
Dissociation between opiate-like and antidiarrheal activities of antidiarrheal drugs.
Topics: Administration, Oral; Animals; Antidiarrheals; Bridged Bicyclo Compounds; Castor Oil; Codeine; Diphenoxylate; Dose-Response Relationship, Drug; Injections, Intravenous; Lethal Dose 50; Loperamide; Male; Morphine; Narcotics; Oxadiazoles; Rats; Reaction Time | 1979 |
On the antidiarrhoeal and analgesic properties of diphenoxylate, difenoxine and loperamide in mice and rats.
Topics: Analgesics; Animals; Antidiarrheals; Diphenoxylate; Isonipecotic Acids; Loperamide; Male; Meperidine; Mice; Piperidines; Rats | 1977 |
In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide.
Topics: Amidines; Animals; Antidiarrheals; Carbachol; Charcoal; Cholera Toxin; Diarrhea; Diphenoxylate; Feces; Gastrointestinal Motility; Isonipecotic Acids; Loperamide; Male; Piperidines; Prostaglandins E; Rats; Serotonin; Stomach | 1978 |
[Special consideration of clinical and travelling medical criteria (author's transl)].
Topics: Diarrhea; Diphenoxylate; Humans; Isonipecotic Acids; Loperamide; Travel | 1979 |
[Seriousness factors in acute poisoning].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Belgium; Child; Child, Preschool; Chloroquine; Colchicine; Diphenoxylate; Environmental Exposure; Female; Humans; Infant; Loperamide; Male; Medication Errors; Middle Aged; Poison Control Centers; Poisoning; Suicide, Attempted | 1978 |
Interaction of loperamide and diphenoxylate with ethanol and methohexital.
Topics: Animals; Diphenoxylate; Drug Interactions; Ethanol; Hypnotics and Sedatives; Isonipecotic Acids; Loperamide; Male; Methohexital; Mice; Piperidines; Rats; Reflex | 1978 |
Lomotil overdose.
Topics: Atropine; Child, Preschool; Diphenoxylate; Drug Combinations; Drug Overdose; Gastrointestinal Agents; Humans; Incidence; Infant; Loperamide; United States | 1992 |
15(S)-15-methyl-prostaglandin F2 alpha used for induction of delivery in the case of intra-uterine fetal death.
Topics: Abortion, Induced; Adult; Carboprost; Diphenoxylate; Female; Fetal Death; Gastrointestinal Diseases; Humans; Injections, Intramuscular; Labor, Induced; Loperamide; Postoperative Complications; Pregnancy; Prostaglandins F, Synthetic | 1985 |
Evaluation of gastrointestinal motility using the hydrogen breath test.
Topics: Adult; Breath Tests; Cisapride; Diphenoxylate; Female; Gastric Emptying; Gastrointestinal Motility; Humans; Hydrogen; Lactulose; Loperamide; Male; Metoclopramide; Piperidines; Random Allocation | 1985 |
Relationship between anti-diarrheal activity and binding to calmodulin.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Antidiarrheals; Antipsychotic Agents; Body Fluids; Calcium-Binding Proteins; Calmodulin; Castor Oil; Diarrhea; Diphenoxylate; Female; Intestinal Mucosa; Loperamide; Protein Binding; Rats; Rats, Inbred Strains | 1982 |
Practical therapeutics: approach to the therapy of diarrhoeal diseases.
Topics: Child, Preschool; Developing Countries; Diarrhea; Diphenoxylate; Fluid Therapy; Humans; Loperamide | 1984 |
Use of an elemental diet as a nutritionally complete "medical colostomy".
Topics: Adolescent; Adult; Catheters, Indwelling; Child; Child, Preschool; Codeine; Colostomy; Diphenoxylate; Fecal Incontinence; Female; Food Additives; Food, Formulated; Humans; Infant; Loperamide; Male; Middle Aged; Organic Chemicals | 1983 |
Effect of chemical and pharmacological agents on the secretory activity induced by Escherichia coli heat-stable enterotoxin.
Topics: Animals; Aspirin; Chlorpromazine; Diphenoxylate; Egtazic Acid; Enterotoxins; Escherichia coli; Hydrocortisone; Intestinal Mucosa; Loperamide; Methylprednisolone; Mice; Phentolamine; Propranolol; Trifluoperazine | 1981 |
A semichronic diarrheal model.
Topics: Animals; Chronic Disease; Diarrhea; Dietary Carbohydrates; Diphenoxylate; Disease Models, Animal; Female; Lactose; Loperamide; Male; Morphine; Rats; Rats, Inbred Strains; Sex Factors; Species Specificity | 1982 |
[Effects of several antidiarrheal agents on colon motility].
Topics: Adult; Antidiarrheals; Atropine; Colon; Diphenoxylate; Female; Gastrointestinal Motility; Humans; Isonipecotic Acids; Loperamide; Male; Piperidines | 1982 |
Occasional fecal incontinence among community-dwelling older adults.
Topics: Aged; Aged, 80 and over; Atropine; Combined Modality Therapy; Dietary Fiber; Diphenoxylate; Drug Combinations; Eating; Fecal Incontinence; Female; Gastrointestinal Agents; Humans; Loperamide | 1995 |
Do antidiarrhoeal opiates accumulate in the rat intestinal lumen?
Topics: Absorption; Animals; Antidiarrheals; Calibration; Castor Oil; Chromatography; Diarrhea; Diphenoxylate; Female; Intestinal Mucosa; Intestinal Secretions; Loperamide; Male; Narcotics; Rats; Rats, Wistar; Vasoactive Intestinal Peptide | 1993 |
Attempts to aid the adaptation of pelvic pouch before temporary ileostomy closure.
Topics: Adaptation, Physiological; Atropine; Colectomy; Colitis, Ulcerative; Defecation; Diphenoxylate; Drug Combinations; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Ileostomy; Loperamide; Postoperative Care; Premedication; Proctocolectomy, Restorative | 1993 |
Difenoxin and loperamide: studies on possible mechanisms of intestinal antisecretory action.
Topics: Animals; Antidiarrheals; Diphenoxylate; Dose-Response Relationship, Drug; Drug Interactions; Female; Intestinal Absorption; Jejunum; Loperamide; Male; Models, Biological; Morphine; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, Opioid; Serotonin; Serotonin Antagonists; Vasoactive Intestinal Peptide | 1993 |
The peristaltic reflex in the rat ileum: evidence for functional mu- and delta-opiate receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Antidiarrheals; Diphenoxylate; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ileum; Linear Models; Loperamide; Morphine; Peristalsis; Pyrrolidines; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
Potential roles of P-gp and calcium channels in loperamide and diphenoxylate transport.
Topics: Antidiarrheals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Calcium Channels; Cyclosporine; Cyclosporins; Diphenoxylate; Drug Interactions; Humans; Loperamide; Narcotics; Probenecid; Sulfinpyrazone; Verapamil | 2003 |
Comparison between prospective and retrospective evaluation of Crohn's disease activity index.
Topics: Abdominal Pain; Antidiarrheals; Colonic Diseases; Crohn Disease; Diphenoxylate; Feces; Health Status; Humans; Ileal Diseases; Loperamide; Medical Records; Prospective Studies; Retrospective Studies | 2005 |
[Topic: Treating travelers' diarrhea. When should medication be given?].
Topics: Adult; Anti-Bacterial Agents; Antidiarrheals; Atropine; Bismuth; Child; Cross-Sectional Studies; Diarrhea; Diphenoxylate; Drug Combinations; Dysentery; Fluid Therapy; Fluoroquinolones; Humans; Loperamide; Organometallic Compounds; Probiotics; Risk Factors; Salicylates; Travel | 2008 |
Antimicrobial and antimotility agent use in persons with shiga toxin-producing Escherichia coli O157 infection in FoodNet Sites.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Case-Control Studies; Child; Child, Preschool; Diphenoxylate; Escherichia coli Infections; Escherichia coli O157; Hemolytic-Uremic Syndrome; Humans; Loperamide; Parasympatholytics; Population Surveillance; Practice Patterns, Physicians'; Shiga Toxins; Young Adult | 2011 |
Chronic Norovirus Infections in Cardiac Transplant Patients.
Topics: Adult; Antidiarrheals; Atropine; Caliciviridae Infections; Chronic Disease; Diphenoxylate; Drug Combinations; Female; Gastrointestinal Agents; Heart Transplantation; Humans; Immunosuppressive Agents; Loperamide; Male; Middle Aged; Polymerase Chain Reaction; Transplant Recipients | 2017 |
Ventricular Arrhythmias Associated With Over-the-Counter and Recreational Opioids.
Topics: Analgesics, Opioid; Arrhythmias, Cardiac; Buprenorphine; Diphenoxylate; Humans; Loperamide; Methadone; Naltrexone; Nonprescription Drugs | 2023 |