diphenidine has been researched along with ketamine in 4 studies
*Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors. [MeSH]
*Ketamine: A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors. [MeSH]
| Studies (diphenidine) | Trials (diphenidine) | Recent Studies (post-2010) (diphenidine) | Studies (ketamine) | Trials (ketamine) | Recent Studies (post-2010) (ketamine) |
|---|---|---|---|---|---|
| 18 | 0 | 16 | 15,029 | 2,321 | 6,678 |
| Protein | Taxonomy | diphenidine (IC50) | ketamine (IC50) |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 4.216 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 4.216 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 3.7762 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 3.5563 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 4.1059 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 5.02 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 5.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brandt, SD; Dempster, NM; Elliott, SP; Kavanagh, PV; Lodge, D; McLaughlin, G; Mercier, MS; Morris, H; Morris, N; Power, JD; Wallach, J | 1 |
| Adejare, A; Bortolotto, ZA; Brandt, SD; Colestock, T; Collingridge, GL; Halberstadt, AL; Kang, H; Lodge, D; Morris, H; Wallach, J | 1 |
| Adejare, A; Brandt, SD; Colestock, T; Elliott, SP; Filemban, N; Mansi, M; Morris, H; Wallach, J; Westphal, F | 1 |
| Choi, SO; Han, B; Kang, MS; Kim, JM; Kim, YH; Min, HK; Yun, J | 1 |
4 other study(ies) available for diphenidine and ketamine
| Article | Year |
|---|---|
Preparation and characterization of the 'research chemical' diphenidine, its pyrrolidine analogue, and their 2,2-diphenylethyl isomers.
Topics: Animals; Chemistry Techniques, Analytical; Excitatory Postsynaptic Potentials; Female; Hippocampus; Isomerism; Ketamine; Male; Piperidines; Pyrrolidines; Rats | 2015 |
Pharmacological Investigations of the Dissociative 'Legal Highs' Diphenidine, Methoxphenidine and Analogues.
Topics: Acetamides; Analgesics, Opioid; Animals; Drug Overdose; Humans; Ketamine; Phencyclidine; Phenethylamines; Piperidines; Psychotropic Drugs; Pyridines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin | 2016 |
Syntheses, analytical and pharmacological characterizations of the 'legal high' 4-[1-(3-methoxyphenyl)cyclohexyl]morpholine (3-MeO-PCMo) and analogues.
Topics: Anesthetics, Dissociative; Animals; Humans; Ketamine; Morpholines; Phencyclidine; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate | 2018 |
Rewarding and reinforcing effects of two dissociative-based new psychoactive substances, deschloroketamine and diphenidine, in mice.
Topics: Animals; Behavior, Animal; Conditioning, Classical; Dopamine; Ketamine; Locomotion; Male; Mice; Mice, Inbred C57BL; PC12 Cells; Piperidines; Psychotropic Drugs; Rats; Reinforcement, Psychology; Reward; Self Administration; Stereotyped Behavior | 2022 |