diphenhydramine hydrochloride has been researched along with quinidine in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Giuliano, H | 1 |
| Bochner, F; Capon, DA; Danz, C; Kerry, N; Mikus, G; Somogyi, AA | 1 |
| Fogelman, SM; Greenblatt, DJ; Schmider, J; Shader, RI; von Moltke, LL | 1 |
| Abdul Manap, R; Gregory, A; Kelm, GR; Lennard, MS; Meller, ST; Morice, AH; Rostami-Hodjegan, A; Tucker, GT; Wright, CE | 1 |
| Abdul-Manap, R; Moghadamnia, AA; Morice, AH; Rostami-Hodjegan, A; Tucker, GT; Wright, CE | 1 |
| Axelsson, H; Floby, E; Granhall, C; Jaksch, Y; Sohlenius-Sternbeck, AK; Svedling, M | 1 |
| Berg, JE; Marier, JF; Pope, LE; Stiles, M; Vachon, P; Yakatan, GJ | 1 |
| Bhoopathy, S; Karnes, HT; Unger, SE; Xin, B | 1 |
| Hingorani, VN; Kittrelle, JP | 1 |
| Hayashi, M; Hirasawa-Inoue, A; Matsumoto, N; Matsumura, Y; Mizuguchi, T; Shirai, K; Sugai, K; Takase, C; Watanabe, A; Watanabe, T | 1 |
| Kverno, K | 1 |
3 trial(s) available for diphenhydramine hydrochloride and quinidine
| Article | Year |
|---|---|
The influence of CYP2D6 polymorphism and quinidine on the disposition and antitussive effect of dextromethorphan in humans.
Topics: Adult; Aerosols; Anti-Arrhythmia Agents; Antitussive Agents; Area Under Curve; Capsaicin; Chromatography, High Pressure Liquid; Cough; Cytochrome P-450 CYP2D6; Dextromethorphan; Female; Humans; Male; Matched-Pair Analysis; Polymorphism, Genetic; Quinidine; Reference Values | 1996 |
The antitussive effect of dextromethorphan in relation to CYP2D6 activity.
Topics: Adolescent; Adult; Antitussive Agents; Cough; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Quinidine; Treatment Outcome | 1999 |
Physiologically based modelling of inhibition of metabolism and assessment of the relative potency of drug and metabolite: dextromethorphan vs. dextrorphan using quinidine inhibition.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Antitussive Agents; Cough; Cross-Over Studies; Dextromethorphan; Dextrorphan; Double-Blind Method; Female; Humans; Male; Quinidine | 2003 |
10 other study(ies) available for diphenhydramine hydrochloride and quinidine
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A comparison of the cardiac activity of a new antiarrhythmic drug--pipazetate--with quinidine, procainamide, antazoline and diphenylhydantoin.
Topics: Animals; Anti-Arrhythmia Agents; Antitussive Agents; Atrial Function; Depression, Chemical; Dogs; Heart; Histamine H1 Antagonists; Imidazoles; In Vitro Techniques; Mice; Muscle Contraction; Phenytoin; Procainamide; Quinidine; Rabbits; Reaction Time; Thiazines | 1970 |
Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.
Topics: Animals; Antitussive Agents; Benzoflavones; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Ditiocarb; Enzyme Inhibitors; Humans; In Vitro Techniques; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Quinidine; Rats; Sulfaphenazole; Tissue Donors | 1997 |
Rates of metabolism of chlorzoxazone, dextromethorphan, 7-ethoxycoumarin, imipramine, quinidine, testosterone and verapamil by fresh and cryopreserved rat liver slices, and some comparisons with microsomes.
Topics: Animals; Antidepressive Agents; Antimalarials; Antitussive Agents; Calcium Channel Blockers; Cell Survival; Chlorzoxazone; Coloring Agents; Coumarins; Cryopreservation; Cytochrome P-450 Enzyme System; Dextromethorphan; Imipramine; In Vitro Techniques; Liver; Male; Microsomes, Liver; Muscle Relaxants, Central; Oxazines; Pharmaceutical Preparations; Pharmacokinetics; Quinidine; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Testosterone; Verapamil; Xanthenes | 2003 |
Influence of concomitant quinidine administration on dextromethorphan disposition in rats.
Topics: Animals; Antitussive Agents; Area Under Curve; Dextromethorphan; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Metabolic Clearance Rate; Quinidine; Rats; Rats, Sprague-Dawley | 2004 |
A novel incubation direct injection LC/MS/MS technique for in vitro drug metabolism screening studies involving the CYP 2D6 and the CYP 3A4 isozymes.
Topics: Algorithms; Animals; Antitussive Agents; Chlorpromazine; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Inhibitors; Half-Life; Humans; Hypnotics and Sedatives; In Vitro Techniques; Indicators and Reagents; Isoenzymes; Microsomes, Liver; Midazolam; Pharmaceutical Preparations; Primaquine; Quinidine; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2005 |
Treatment of pseudobulbar affect in ALS: October 26 highlight and commentary.
Topics: Amyotrophic Lateral Sclerosis; Antitussive Agents; Clinical Trials as Topic; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Combinations; Drug Resistance; Drug Synergism; Enzyme Inhibitors; Genetic Testing; Genotype; Humans; Pseudobulbar Palsy; Quinidine | 2005 |
KCNT1-positive epilepsy of infancy with migrating focal seizures successfully treated with nonnarcotic antitussive drugs after treatment failure with quinidine: A case report.
Topics: Antitussive Agents; Dextromethorphan; Electroencephalography; Epilepsy; Humans; Infant; Magnetic Resonance Imaging; Male; Mutation; Nerve Tissue Proteins; Piperidines; Potassium Channels, Sodium-Activated; Quinidine; Seizures; Treatment Failure; Treatment Outcome | 2020 |
Dextromethorphan: From Cough Suppressant to Antidepressant.
Topics: Antidepressive Agents; Antitussive Agents; Depressive Disorder, Major; Dextromethorphan; Humans; Quinidine | 2022 |