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diphenhydramine hydrochloride and pholcodine

diphenhydramine hydrochloride has been researched along with pholcodine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199010 (29.41)18.7374
1990's5 (14.71)18.2507
2000's9 (26.47)29.6817
2010's8 (23.53)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Shohet, JS1
Johansen, M; Rasmussen, KE; Tønnesen, F1
Christophersen, AS; Johansen, M; Rasmussen, KE; Skuterud, B1
Fritz, CF; Maurer, HH1
Bochner, F; Chen, ZR; Somogyi, A1
Findlay, JW1
Butz, RF; Findlay, JW; Fowle, AS; Jones, EC; Posner, J; Weatherley, BC; Welch, RM1
Carnevale, L1
Artemi, P; Holt, D; Lee, S1
Kivistö, KT; Laine, K; Neuvonen, PJ; Ojala-Karlsson, P1
Denk, OM; Gray, AI; Skellern, GG; Watson, DG1
Denk, OM; Skellern, GG; Watson, DG1
Braithwaite, R; George, S; Meadway, C1
Grant, MH; Gray, AI; Jairaj, M; Skellern, GG; Watson, DG1
ARMITAGE, P; SNELL, ES1
MULINOS, MG1
GRABELLE, BN1
PLISNIER, H1
EPSTEIN, IG; MULINOS, MG; NAIR, KG1
Codreanu, F; Kanny, G; Moneret-Vautrin, DA; Morisset, M1
Degerbeck, F; Dybendal, T; Florvaag, E; Johansson, SG; Lundberg, M; Oman, H; Venemalm, L1
Florvaag, E; Harboe, T; Johansson, SG; Nopp, A; Oman, H1
Florvaag, E; Harboe, T; Johansson, SG; Oman, H1
Florvaag, E; Johansson, SG2
Dybendal, T; Florvaag, E; Garvey, LH; Gerth van Wijk, R; Guttormsen, AB; Halsey, J; Harper, NJ; Irgens, A; Johansson, SG; Mertes, PM; Metso, T; Oman, H; Poulsen, LK; Seneviratne, SL1
de Pater, GH; Florvaag, E; Irgens, Å; Johansson, SG1
Degerbeck, F; Florvaag, E; Johansson, SG; Nopp, A; Oman, H; Tunelli, J1
Dumancić, J; Marković, AS1
Boret, H; D'Aranda, E; Esnault, P; Gaillard, Y; Lacroix, G; Prunet, B1
Desmeules, J; Ing Lorenzini, K; Piguet, V1
Ali, O; Hegazy, MA; Mohamed, D; Moustafa, AA1
Acker, JV; Aerts, O; Coghe, M; Ebo, D; Faber, M; Sabato, V; Suys, E1
Bévalot, F; Cartiser, N; Epain, M; Fanton, L1

Reviews

2 review(s) available for diphenhydramine hydrochloride and pholcodine

ArticleYear
Pholcodine.
    Journal of clinical pharmacy and therapeutics, 1988, Volume: 13, Issue:1

    Topics: Antitussive Agents; Codeine; Humans; Morpholines

1988
[Correlation between pholcodine and perioperative anaphylaxis].
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti, 2012, Volume: 66, Issue:2

    Topics: Anaphylaxis; Antitussive Agents; Codeine; Cross Reactions; Humans; Immunotherapy; Intraoperative Complications; Morpholines; Neuromuscular Blocking Agents; Postoperative Complications

2012

Trials

4 trial(s) available for diphenhydramine hydrochloride and pholcodine

ArticleYear
Pharmacokinetics of pholcodine in healthy volunteers: single and chronic dosing studies.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:4

    Topics: Adult; Antitussive Agents; Codeine; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Morpholines; Saliva

1988
Effect of activated charcoal on the pharmacokinetics of pholcodine, with special reference to delayed charcoal ingestion.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:1

    Topics: Adult; Antidotes; Antitussive Agents; Area Under Curve; Charcoal; Codeine; Female; Humans; Intestinal Absorption; Male; Morpholines; Time Factors

1997
Interpretation of GC-MS opiate results in the presence of pholcodine.
    Forensic science international, 2002, Jun-25, Volume: 127, Issue:1-2

    Topics: Antitussive Agents; Codeine; Drug Interactions; Gas Chromatography-Mass Spectrometry; Humans; Morphine; Morpholines; Substance-Related Disorders

2002
Pholcodine exposure raises serum IgE in patients with previous anaphylaxis to neuromuscular blocking agents.
    Allergy, 2007, Volume: 62, Issue:12

    Topics: Adult; Allergens; Anaphylaxis; Antitussive Agents; Codeine; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Male; Middle Aged; Morphine; Morpholines; Neuromuscular Blocking Agents; Skin Tests; Succinylcholine; Treatment Outcome

2007

Other Studies

28 other study(ies) available for diphenhydramine hydrochloride and pholcodine

ArticleYear
Analysis of pholcodine in cough preparations.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:6

    Topics: Antitussive Agents; Codeine; Colorimetry; Morpholines; Technology, Pharmaceutical

1975
Column-switching high-performance liquid chromatographic detection of pholcodine and its metabolites in urine with fluorescence and electrochemical detection.
    Journal of chromatography, 1992, Jan-17, Volume: 573, Issue:2

    Topics: Antitussive Agents; Chromatography, High Pressure Liquid; Codeine; Electrochemistry; Humans; Morphine; Morpholines; Spectrometry, Fluorescence

1992
Metabolic study of pholcodine in urine using enzyme multiplied immunoassay technique (EMIT) and capillary gas chromatography.
    Acta pharmaceutica Nordica, 1991, Volume: 3, Issue:2

    Topics: Adult; Antitussive Agents; Chromatography, Gas; Codeine; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Morpholines

1991
[Forensic-toxicologic detection of pholcodine in urine and hair].
    Beitrage zur gerichtlichen Medizin, 1990, Volume: 48

    Topics: Antitussive Agents; Codeine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Morpholines; Urine

1990
Comparative disposition of codeine and pholcodine in man after single oral doses.
    British journal of clinical pharmacology, 1986, Volume: 22, Issue:1

    Topics: Administration, Oral; Adult; Antitussive Agents; Codeine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Kinetics; Male; Morphine; Morpholines; Pupil; Radioimmunoassay

1986
Simultaneous determination of acetaminophen, guaifenesin, pseudoephedrine, pholcodine, and paraben preservatives in cough mixture by high-performance liquid chromatography.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:2

    Topics: Acetaminophen; Antitussive Agents; Chromatography, High Pressure Liquid; Codeine; Drug Combinations; Ephedrine; Guaifenesin; Morpholines; Parabens

1983
Acute generalized exanthematous pustulosis.
    The Australasian journal of dermatology, 1995, Volume: 36, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Antitussive Agents; Codeine; Diagnosis, Differential; Drug Eruptions; Exanthema; Female; Humans; Morpholines; Prednisone; Psoriasis

1995
Isolation and identification of three potential impurities of pholcodine bulk drug substance.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:7

    Topics: Antitussive Agents; Chloroform; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Codeine; Drug Contamination; Mass Spectrometry; Morpholines; Spectrophotometry, Ultraviolet

2000
Impurity profiling of pholcodine by liquid chromatography electrospray ionization mass spectrometry (LC-ESI-MS).
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:1

    Topics: Antitussive Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Codeine; Drug Contamination; Morpholines; Spectrometry, Mass, Electrospray Ionization

2002
Comparative biotransformation of morphine, codeine and pholcodine in rat hepatocytes: identification of a novel metabolite of pholcodine.
    Xenobiotica; the fate of foreign compounds in biological systems, 2002, Volume: 32, Issue:12

    Topics: Analgesics, Opioid; Animals; Antitussive Agents; Chromatography, Liquid; Codeine; Glucuronidase; Hepatocytes; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Models, Chemical; Morphine; Morpholines; Oxygen; Rats; Spectrometry, Mass, Electrospray Ionization; Time Factors

2002
Clinical comparison of diamorphine and pholcodine as cough suppressants by a new method of sequential analysis.
    Lancet (London, England), 1957, Apr-27, Volume: 272, Issue:6974

    Topics: Antitussive Agents; Codeine; Cough; Heroin; Humans; Morphine Derivatives; Morpholines

1957
Antitussive properties of morpholinethyl-morphine (pholcodine).
    Toxicology and applied pharmacology, 1960, Volume: 2

    Topics: Antitussive Agents; Codeine; Cough; Morphine Derivatives; Morpholines

1960
Antitussive therapy with pholcodine.
    The Journal of the Medical Society of New Jersey, 1961, Volume: 58

    Topics: Antitussive Agents; Codeine; Cough; Morphine Derivatives; Morpholines

1961
[Apropos of the antitussive and xronchoconstrictive properties of tetrahydro-1,4-oxazinylmethyl-codeine (pholcodine)].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1960, Volume: 154

    Topics: Antitussive Agents; Bronchi; Codeine; Cough; Morphine Derivatives; Morpholines

1960
Clinical investigation of antitussive properties of pholcodine.
    New York state journal of medicine, 1962, Jul-15, Volume: 62

    Topics: Antitussive Agents; Codeine; Cough; Morphine Derivatives; Morpholines

1962
Allergy to pholcodine: first case documented by oral challenge.
    Allergy, 2005, Volume: 60, Issue:4

    Topics: Administration, Oral; Adult; Angioedema; Antitussive Agents; Codeine; Drug Hypersensitivity; Female; Humans; Laryngeal Diseases; Morpholines; Pharyngitis; Skin Tests

2005
Prevalence of IgE antibodies to morphine. Relation to the high and low incidences of NMBA anaphylaxis in Norway and Sweden, respectively.
    Acta anaesthesiologica Scandinavica, 2005, Volume: 49, Issue:4

    Topics: Algorithms; Analgesics, Opioid; Anaphylaxis; Antitussive Agents; Blood Donors; Codeine; Cross Reactions; Environmental Pollutants; Humans; Immunoglobulin E; Morphine; Morpholines; Neuromuscular Blocking Agents; Neuromuscular Depolarizing Agents; Norway; Succinylcholine; Sweden

2005
Pholcodine stimulates a dramatic increase of IgE in IgE-sensitized individuals. A pilot study.
    Allergy, 2006, Volume: 61, Issue:1

    Topics: Adult; Allergens; Antitussive Agents; Codeine; Enzyme-Linked Immunosorbent Assay; Female; Galectin 3; Humans; Hypersensitivity; Immunization; Immunoglobulin E; Leukocytes, Mononuclear; Male; Morphine; Morpholines; Neuromuscular Blocking Agents; Pilot Projects; Sensitivity and Specificity; Succinylcholine

2006
IgE-mediated anaphylactic reactions to neuromuscular blocking agents: can they be prevented?
    Current allergy and asthma reports, 2008, Volume: 8, Issue:5

    Topics: Analgesics; Anaphylaxis; Anesthesia; Antitussive Agents; Codeine; Drug Hypersensitivity; Drug Utilization; Humans; Immunoglobulin E; Morpholines; Neuromuscular Depolarizing Agents; Norway; Succinylcholine; Sweden

2008
National pholcodine consumption and prevalence of IgE-sensitization: a multicentre study.
    Allergy, 2010, Volume: 65, Issue:4

    Topics: Anaphylaxis; Antitussive Agents; Codeine; Cross Reactions; Drug Hypersensitivity; Humans; Immunoglobulin E; Morphine; Morpholines; Neuromuscular Agents; Phosphorylcholine; Prevalence; Quaternary Ammonium Compounds; Succinylcholine

2010
IgE-sensitization to the cough suppressant pholcodine and the effects of its withdrawal from the Norwegian market.
    Allergy, 2011, Volume: 66, Issue:7

    Topics: Anaphylaxis; Antitussive Agents; Codeine; Drug Hypersensitivity; Humans; Immunoglobulin E; Morpholines; Neuromuscular Blocking Agents; Norway; Safety-Based Drug Withdrawals

2011
Anaphylaxis to atracurium - a non-QAI-dependent reaction?
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:2

    Topics: Anaphylaxis; Antitussive Agents; Atracurium; Codeine; Humans; Morpholines; Neuromuscular Nondepolarizing Agents; Norway; Quaternary Ammonium Compounds; Sweden

2012
Pholcodine in cough medicines and IgE-sensitization in the EU: an urgent task.
    Allergy, 2012, Volume: 67, Issue:5

    Topics: Anaphylaxis; Antitussive Agents; Codeine; Cough; European Union; Evidence-Based Medicine; Humans; Immunoglobulin E; Morpholines

2012
Instantaneous rigor after fatal pholcodine intoxication.
    British journal of clinical pharmacology, 2014, Volume: 77, Issue:3

    Topics: Antitussive Agents; Autopsy; Codeine; Death, Sudden, Cardiac; Drug Overdose; Fatal Outcome; Heart Arrest; Humans; Male; Middle Aged; Morpholines; Spasm; Time Factors; Trismus

2014
Is pholcodine a dangerous cough suppressant?
    European journal of anaesthesiology, 2015, Volume: 32, Issue:11

    Topics: Antitussive Agents; Codeine; Humans; Intraoperative Complications; Morpholines; Neuromuscular Blocking Agents

2015
Novel Approach for the Simultaneous Determination of Carbinoxamine Maleate, Pholcodine, and Ephedrine Hydrochloride Without Interference from Coloring Matter in an Antitussive Preparation Using Smart Spectrophotometric Methods.
    Journal of AOAC International, 2018, Mar-01, Volume: 101, Issue:2

    Topics: Antitussive Agents; Azo Compounds; Codeine; Coloring Agents; Ephedrine; Limit of Detection; Morpholines; Pyridines; Spectrophotometry

2018
A bad cough: Delayed cutaneous hypersensitivity caused by pholcodine.
    The journal of allergy and clinical immunology. In practice, 2020, Volume: 8, Issue:4

    Topics: Antitussive Agents; Codeine; Cough; Dermatitis, Atopic; Humans; Hypersensitivity, Delayed; Morpholines

2020
Toxicological detection of pholcodine in blood, urine and hair in three cases of fatal intoxication.
    Forensic science international, 2021, Volume: 327

    Topics: Antitussive Agents; Autopsy; Codeine; Fatal Outcome; Female; Forensic Toxicology; Hair Analysis; Humans; Middle Aged; Morpholines; Young Adult

2021