diphenhydramine hydrochloride and noscapine

diphenhydramine hydrochloride has been researched along with noscapine in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	29 (33.72)	18.7374
1990's	5 (5.81)	18.2507
2000's	19 (22.09)	29.6817
2010's	28 (32.56)	24.3611
2020's	5 (5.81)	2.80

Authors

Authors	Studies
Hughes, DT	1
Bye, CE; Empey, DW; Hughes, DT; Laitinen, LA; Young, GA	1
De Ritis, G	1
Kamikawa, Y; Shimo, Y	1
Kamei, J; Kasuya, Y; Mori, T	1
Kamei, J; Kasuya, Y; Mori, T; Ogawa, M	1
Koike, Y; Misawa, M; Suzuki, T; Yanaura, S; Yoshida, E; Yoshii, T	1
Dahlström, B; Karlsson, MO; Neil, A	1
Erhardt, J; Matthys, H; Rühle, KH	1
Engelhorn, R; Weller, E	1
Farriaux, JP; Fontaine, G	1
Kas0e, Y; Kito, G; Yuizono, T	1
Kasé, Y; Kito, G; Yuizono, T	1
Fritz, M; Strohe, A	1
Emele, JF; Fainman, FB; Sanzari, NP	1
Bálint, G; Rablóczky, G	1
Idänpään-Heikkilä, JE	1
Wulff, O	1
McGrath, G; Smyth, WF	1
Carducci, CN; Fernández Otero, G; Lucangioli, S; Rodríguez, V	1
Arnera, V; Chollet, DF; Ruols, C	1
Klemenc, S	1
Archer, DR; Grossniklaus, HE; Joshi, HC; Kapp, JA; Ke, Y; Ye, K	1
Bradbury, EM; Joshi, HC; Landen, JW; Ye, K; Zhou, J	1
Mahmoudian, M; Mojaverian, N	1
Giannakakou, P; Gupta, K; Joshi, HC; Panda, D; Yao, J; Ye, K; Zhou, J	1
Aggarwal, S; Aneja, R; Chandra, R; Gupta, K; Joshi, HC; Panda, D; Zhou, J	1
Eastmond, DA; Guzzie, P; Muehlbauer, P; Schuler, M	1
Ebrahimi, SA; Mahmoudian, M; Rostami, P; Zareie, MR	1
Tang, C; Wu, X; Yin, C	1
ATTINGER, EO; GOLDSTEIN, MM; SEGAL, MS	1
LA BARRE, J; PLISNIER, H	1
GOMES, FP; LEAL, F	1
CARRIZO, AR	1
AGUET, F; BARASZ, Z; BONSTEIN, H; FAVEZ, G	1
BONER, H	1
STROHE, A	1
ABSIRE-LAUPRETRE, Y; DAILLY, R	1
BLANKART, R	1
BANFI, S; MAFFII, G; SILVESTRINI, B	1
BEIRN, SF; LAVELLE, S	1
AVIADO, DM; SALEM, H	1
ENDO, N; HIRASAWA, M; OTA, Y	1
Benaissa, F; Mahmoudian, M; Mehrpour, M; Nobakht, M; Siadatpour, Z; Ziai, SA	1
Archer, DR; Ciliax, B; Davis, T; Glass, JD; Hau, V; Joshi, HC; Landen, JW; Van Meir, EG; Wainer, BH; Wang, M	1
Gomez, MR; Martínez, LD; Olsina, RA; Silva, MF; Sombra, L	1
Bastani, B; Jabbari, M; Javanmardi, SZ; Jenabi, A; Mahmoudian, M; Mooraki, A; Zolfaghari, MI	1
Aneja, R; Joshi, HC; Vangapandu, SN	1
Goliaei, B; Heidari, N; Mahmoudian, M; Moghaddam, PR; Rahbar-Roshandel, N	1
Khayamian, T; Mokhtari, A; Rezaei, B	2
Myhr, K	1
Aneja, R; Karna, P; Stephens, D; Zughaier, S	1
Fang, ZZ; Ge, GB; Huo, H; Liang, SC; Yang, L; Zhang, YY	1
Barken, I; Geller, J; Rogosnitzky, M	1
Aggarwal, BB; Ahn, KS; Sung, B	1
Ashour, A; Fattah, LE; Hegazy, MA; Kelani, KO; Moustafa, AA	1
Bielejewska, A; Bylina, A; Duszczyk, K; Fiałkowski, M; Hołyst, R	1
Li, X; Liang, S; Liu, B; Lü, H; Qiu, Z; Wang, L; Wang, Y; Wei, W; Yu, L	1
Bertilsson, L; Eliasson, E; Masquelier, M; Ostervall, J; Otto, S; Rosenborg, S; Stenberg, M; Yue, QY	1
Abdalla, MO; Aneja, R; Karna, P; Mao, H; Sajja, HK; Turner, T; Yates, C	1
Hamasaki, Y; Hatamochi, A; Hayashi, S; Ishiguro, E; Yamazaki, S	1
Joshi, HC; Naik, PK; Rai, A; Santoshi, S	1
Aneja, R; Chandra, R; Chatterji, BP; Joshi, HC; Kanteveri, S; Naik, PK; Vangapandu, SN	1
Alisaraie, L; Tuszynski, JA	1
Chougule, MB; Jackson, T; Patel, A; Sachdeva, P; Singh, M	1
Bureau, F; Desmet, CJ; Farnir, F; Fievez, L; Lekeux, P; Pirottin, D; Toussaint, M	1
Cao, G; He, J; Joshi, HC; Li, S; Tang, S; Tong, Q	1
Chandra, A; Chandra, R; Dass, SK; Kumari, K; Singh, H; Singh, P	1
Capuano, B; DeBono, AJ; Pouton, CW; Scammells, PJ; Ventura, S; Xie, JH	1
Akimova, O; Denner, D; Dulin, NO; Kach, J; Koltsova, S; La, J; Orlov, SN; Reed, EB; Sandbo, N	1
Aneja, R; Bharatam, PV; Gundala, SR; Jain, UK; Kasetti, Y; Katyal, A; Madan, J	1
Chougule, MB; Jackson, T; Patel, AR; Patlolla, R; Singh, M	1
Cheng, J; Li, X; Liang, B; Shen, W; Yin, J	1
Chen, X; Dang, TT; Facchini, PJ	1
Aneja, R; Gundala, SR; Jadhav, GR; Mukkavilli, R; Reid, MD; Vangala, S; Yang, C	1
Chandra, R; Kukreti, S; Madan, J; Prakash, S; Tomar, V	1
Choudhary, S; Kantevari, S; Lopus, M; Mahaddalkar, T; Manchukonda, N; Naik, PK	1
Amani, A; Azarian, M; Divsalar, A; Eidi, A; Faramarzi, MA	1
Jessurun, NT; Lokhorst, B; Rolfes, L	1
Barati, M; Golab, F; Jafari-Sabet, M; Moazam, A; Mohamadrezaei, H; Safari, S; Soltani, H; Vahabzadeh, G	1
Awasthi, A; Chandra, R; Grover, A; Jain, P; Kumar, N; Kumari, A; Sharma, N; Singh, T; Sood, D	1
Fabre, F; Gibaja, V; Jouanjus, E; Lapeyre-Mestre, M	1
Askari, VR; Nourbakhsh, F	1
Chang, MY; Chen, KH; Hsu, HH; Hung, CC; Ko, YC; Yang, CW; Yang, HY	1

Reviews

5 review(s) available for diphenhydramine hydrochloride and noscapine

Article	Year
ANTITUSSIVE DRUGS, WITH SPECIAL REFERENCE TO A NEW THEORY FOR THE INITATION OF THE COUGH REFLEX AND THE INFLUENCE OR BRONCHODILATORS. The American journal of the medical sciences, 1964, Volume: 247 Topics: Acetaminophen; Aerosols; Aminophylline; Analgesics; Analgesics, Non-Narcotic; Animals; Antimony; Antipyretics; Antitussive Agents; Ascorbic Acid; Bronchodilator Agents; Caffeine; Codeine; Cough; Dogs; Electric Stimulation; Electrophysiology; Expectorants; Histamine H1 Antagonists; Hypnotics and Sedatives; Ion Exchange Resins; Noscapine; Parasympatholytics; Pharmacology; Phenothiazines; Promethazine; Reflex; Research; Sodium Salicylate; Sympathomimetics	1964
A review on noscapine, and its impact on heme metabolism. Current drug metabolism, 2013, Volume: 14, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Antitussive Agents; Cell Cycle; Heme; Humans; Microtubules; Neoplasms; Noscapine	2013
Noscapine comes of age. Phytochemistry, 2015, Volume: 111 Topics: Alkaloids; Antitussive Agents; Benzylisoquinolines; Latex; Molecular Structure; Noscapine; Papaver	2015
Noscapine and its Analogs as Chemotherapeutic Agent: Current updates. Current topics in medicinal chemistry, 2017, Volume: 17, Issue:2 Topics: Antineoplastic Agents; Antitussive Agents; Apoptosis; Humans; Noscapine; Stroke; Structure-Activity Relationship	2017
Biological and pharmacological activities of noscapine: Focusing on its receptors and mechanisms. BioFactors (Oxford, England), 2021, Volume: 47, Issue:6 Topics: Animals; Anti-Inflammatory Agents; Antimalarials; Antineoplastic Agents; Antitussive Agents; Apoptosis; Female; Humans; Mice; Noscapine	2021

Trials

4 trial(s) available for diphenhydramine hydrochloride and noscapine

Article	Year
Comparison of the antitussive effects of codeine phosphate 20 mg, dextromethorphan 30 mg and noscapine 30 mg using citric acid-induced cough in normal subjects. European journal of clinical pharmacology, 1979, Volume: 16, Issue:6 Topics: Antitussive Agents; Citrates; Codeine; Cough; Dextromethorphan; Humans; Levorphanol; Noscapine; Time Factors	1979
[Objectivation of the effect of antitussive agents using tussometry in patients with chronic cough]. Schweizerische medizinische Wochenschrift, 1985, Mar-02, Volume: 115, Issue:9 Topics: Adult; Aged; Antitussive Agents; Bronchitis; Carcinoma, Bronchogenic; Chronic Disease; Clinical Trials as Topic; Codeine; Cough; Dextromethorphan; Double-Blind Method; Humans; Lung Neoplasms; Middle Aged; Noscapine; Tuberculosis, Pulmonary	1985
Efficacy and safety of modified sequential three-step empirical therapy for chronic cough. Respirology (Carlton, Vic.), 2010, Volume: 15, Issue:5 Topics: Adult; Aminophylline; Antitussive Agents; Budesonide; Cetirizine; Chlorpheniramine; Chronic Disease; Cough; Domperidone; Drug Therapy, Combination; Empirical Research; Humans; Methamphetamine; Middle Aged; Noscapine; Omeprazole; Prednisone; Prospective Studies; Quality of Life; Sleep Stages; Treatment Outcome	2010
Clinically significant CYP2C inhibition by noscapine but not by glucosamine. Clinical pharmacology and therapeutics, 2010, Volume: 88, Issue:3 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anticoagulants; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Drug Interactions; Female; Glucosamine; Humans; Losartan; Male; Middle Aged; Noscapine; Omeprazole; Phenotype; Warfarin; Young Adult	2010

Other Studies

77 other study(ies) available for diphenhydramine hydrochloride and noscapine

Article	Year
Diseases of the respiratory system: cough suppressants, expectorants, and mucolytic agents. British medical journal, 1978, May-06, Volume: 1, Issue:6121 Topics: Antitussive Agents; Codeine; Cough; Dextromethorphan; Drug Combinations; Drug Therapy, Combination; Expectorants; Histamine H1 Antagonists; Humans; Noscapine	1978
[Clinical study on a antitussive syrup based on noscapinium chloride]. La Clinica terapeutica, 1976, Aug-31, Volume: 78, Issue:4 Topics: Adolescent; Adult; Aged; Antitussive Agents; Cough; Drug Combinations; Drug Evaluation; Female; Guaifenesin; Humans; Male; Middle Aged; Noscapine; Solutions	1976
Inhibitory effects of non-narcotic antitussive drugs on cholinergically and non-cholinergically mediated neurogenic contractions of guinea-pig isolated bronchial muscle. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:4 Topics: Animals; Antitussive Agents; Bronchi; Dextromethorphan; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Noscapine; Parasympathetic Nervous System; Piperidines	1991
Effects of L-tryptophan on the effects of antitussives. Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:4 Topics: Animals; Antitussive Agents; Brain; Codeine; Dextromethorphan; Drug Interactions; Male; Noscapine; Rats; Rats, Inbred Strains; Serotonin; Substance-Related Disorders; Tryptophan	1990
Subsensitivity to the cough-depressant effects of opioid and nonopioid antitussives in morphine-dependent rats: relationship to central serotonin function. Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:3 Topics: Animals; Antitussive Agents; Brain Stem; Codeine; Cough; Dextromethorphan; Levorphanol; Male; Morphine; Noscapine; Rats; Rats, Inbred Strains; Receptors, Serotonin	1989
[The effects of noscapine and chlorpheniramine on physical dependence and antitussive activity of dihydrocodeine]. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1988, Volume: 8, Issue:2 Topics: Animals; Antitussive Agents; Body Weight; Chlorpheniramine; Codeine; Drug Interactions; Guinea Pigs; Male; Noscapine; Rats; Rats, Inbred Strains; Substance-Related Disorders	1988
Characterization of high-affinity binding sites for the antitussive [3H]noscapine in guinea pig brain tissue. European journal of pharmacology, 1988, Jan-12, Volume: 145, Issue:2 Topics: Animals; Antitussive Agents; Binding Sites; Binding, Competitive; Brain; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Noscapine; Stereoisomerism; Tritium	1988
[The effect of codeine, dextromethorphane and narcotine on expiratory discharged neurons of the medulla oblongata of the cat]. Naunyn-Schmiedebergs Archiv fur Pharmakologie und experimentelle Pathologie, 1966, Volume: 254, Issue:2 Topics: Action Potentials; Animals; Antitussive Agents; Cats; Codeine; Cough; Medulla Oblongata; Noscapine; Respiration	1966
[Clinical trial of a new antitussive agent, Teletux, in children]. Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1972, Volume: 17 Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Delayed-Action Preparations; Female; Humans; Infant; Male; Noscapine; Promethazine	1972
The influence of anesthesia on the evaluation of antitussive effect. Japanese journal of pharmacology, 1969, Volume: 19, Issue:1 Topics: Analgesics; Anesthesia; Animals; Antitussive Agents; Benzoates; Cats; Codeine; Cough; Dogs; Electric Stimulation; Female; Gases; Guinea Pigs; Laryngeal Nerves; Male; Morphine; Noscapine; Oxides; Sulfur	1969
The influence of anesthesia on the evaluation of antitussive effected. Japanese journal of pharmacology, 1969, Volume: 19, Issue:1 Topics: Analgesics; Anesthesia; Animals; Antitussive Agents; Benzoates; Cats; Codeine; Cough; Dogs; Electric Stimulation; Female; Gases; Guinea Pigs; Laryngeal Nerves; Male; Morphine; Noscapine; Oxides; Sulfur	1969
[Experiences with a new cough blocking agent with immediate and prolonged effect]. Medizinische Monatsschrift, 1971, Volume: 25, Issue:1 Topics: Adolescent; Adult; Antitussive Agents; Codeine; Cough; Female; Humans; Lung Diseases; Male; Middle Aged; Noscapine; Tartrates	1971
Cough induced by 1,1-dimethyl-4-phenylpiperazinium iodide: a new antitussive method. The Journal of pharmacology and experimental therapeutics, 1968, Volume: 162, Issue:1 Topics: Animals; Antitussive Agents; Benzoates; Cats; Codeine; Cough; Female; Male; Methods; Noscapine; Piperazines; Sympathomimetics	1968
Antitussive effect of autonomic drugs. Acta physiologica Academiae Scientiarum Hungaricae, 1968, Volume: 33, Issue:1 Topics: Ammonia; Animals; Antitussive Agents; Atropine; Autonomic Agents; Blood Pressure; Brain; Cats; Cocaine; Codeine; Cough; Drug Antagonism; Drug Synergism; Electric Stimulation; Ephedrine; Ergotamine; Female; Laryngeal Nerves; Lobeline; Male; Noscapine; Respiration; Sympatholytics; Sympathomimetics; Yohimbine	1968
Effect of some antitussives on the uptake and release of labelled choline and acetylcholine in electrically stimulated guinea-pig ileum. Annales medicinae experimentalis et biologiae Fenniae, 1968, Volume: 46, Issue:2 Topics: Acetylcholine; Animals; Antitussive Agents; Carbon Isotopes; Choline; Chromatography, Paper; Codeine; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Noscapine; Papaverine; Physostigmine; Time Factors	1968
Prolonged antitussive action of a resin-bound noscapine preparation. Journal of pharmaceutical sciences, 1965, Volume: 54, Issue:7 Topics: Animals; Antitussive Agents; Codeine; Cough; Guinea Pigs; Noscapine; Resins, Plant	1965
Large-volume sample stacking of selected drugs of forensic significance by capillary electrophoresis. Journal of chromatography. B, Biomedical applications, 1996, May-31, Volume: 681, Issue:1 Topics: Anti-Anxiety Agents; Antitussive Agents; Bronchodilator Agents; Cetrimonium; Cetrimonium Compounds; Chemistry, Clinical; Clenbuterol; Codeine; Detergents; Electrophoresis, Capillary; Flurazepam; Forensic Medicine; Hydrogen-Ion Concentration; Meperidine; Narcotics; Noscapine; Pharmaceutical Preparations; Reproducibility of Results; Spectrophotometry, Ultraviolet; Surface Properties; Time Factors	1996
Determination of noscapine, hexylresorcinol and anethole in cough lozenges by liquid chromatography. Bollettino chimico farmaceutico, 1996, Volume: 135, Issue:6 Topics: Anethole Trithione; Antitussive Agents; Chromatography, Liquid; Hexylresorcinol; Indicators and Reagents; Noscapine; Tablets	1996
Determination of noscapine in human plasma using solid-phase extraction and high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications, 1997, Nov-07, Volume: 701, Issue:1 Topics: Antitussive Agents; Chromatography, High Pressure Liquid; Humans; Noscapine; Reproducibility of Results; Sensitivity and Specificity	1997
Noscapine as an adulterant in illicit heroin samples. Forensic science international, 2000, Jan-24, Volume: 108, Issue:1 Topics: Antitussive Agents; Drug Contamination; Gas Chromatography-Mass Spectrometry; Heroin; Illicit Drugs; Narcotics; Noscapine	2000
Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses. Cancer immunology, immunotherapy : CII, 2000, Volume: 49, Issue:4-5 Topics: Alkaloids; Animals; Antineoplastic Agents; Antitussive Agents; Apoptosis; Bone Marrow; Cell Division; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Immune System; In Situ Nick-End Labeling; Lymphoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Noscapine; Spleen; Tetrahydroisoquinolines; Time Factors; Tissue Distribution; Tumor Cells, Cultured	2000
Sustained activation of p34(cdc2) is required for noscapine-induced apoptosis. The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50 Topics: Animals; Annexin A5; Antitussive Agents; Apoptosis; Blotting, Western; CDC2 Protein Kinase; Cell Line; Enzyme Activation; Flow Cytometry; Fluorescent Dyes; Mice; Mitosis; Mutation; Noscapine; Plasmids; Protein Kinases; Time Factors; Transfection; Tumor Cells, Cultured	2001
Efffect of noscapine, the antitussive opioid alkaloid, on bradykinin-induced smooth muscle contraction in the isolated ileum of the guinea-pig. Acta physiologica Hungarica, 2001, Volume: 88, Issue:3-4 Topics: Animals; Antitussive Agents; Bradykinin; Bradykinin Receptor Antagonists; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Noscapine; Receptor, Bradykinin B2	2001
Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine. The Journal of biological chemistry, 2002, Oct-18, Volume: 277, Issue:42 Topics: Alleles; Antineoplastic Agents, Phytogenic; Antitussive Agents; Apoptosis; Blotting, Western; Cell Death; Cell Division; Cell Nucleus; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Humans; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Microscopy, Fluorescence; Microtubules; Mitogen-Activated Protein Kinases; Models, Chemical; Noscapine; Oligonucleotides, Antisense; Ovarian Neoplasms; Paclitaxel; Plasmids; Precipitin Tests; Protein Binding; Time Factors; Transfection; Tubulin; Tumor Cells, Cultured	2002
Brominated derivatives of noscapine are potent microtubule-interfering agents that perturb mitosis and inhibit cell proliferation. Molecular pharmacology, 2003, Volume: 63, Issue:4 Topics: Antitussive Agents; Bromine; Cell Division; Chromosomes; HeLa Cells; Humans; Kinetochores; Microtubules; Mitosis; Noscapine; Tubulin; Tumor Cells, Cultured	2003
Noscapine hydrochloride-induced numerical aberrations in cultured human lymphocytes: a comparison of FISH detection methods and multiple end-points. Mutagenesis, 2003, Volume: 18, Issue:3 Topics: Aneugens; Aneuploidy; Antitussive Agents; Biomarkers; Cell Division; Chromosomes, Human; Dose-Response Relationship, Drug; Humans; In Situ Hybridization, Fluorescence; Lymphocytes; Noscapine	2003
Interaction of noscapine with the bradykinin mediation of the cough response. Acta physiologica Hungarica, 2003, Volume: 90, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antitussive Agents; Bradykinin; Capsaicin; Captopril; Cough; Dose-Response Relationship, Drug; Drug Interactions; Enalapril; Guinea Pigs; Male; Naloxone; Narcotic Antagonists; Noscapine; Quinolines; Receptor, Bradykinin B2	2003
HPLC determination of aminophylline, methoxyphenamine hydrochloride, noscapine and chlorphenamine maleate in compound dosage forms with an aqueous-organic mobile phase. Journal of pharmaceutical and biomedical analysis, 2003, Sep-15, Volume: 33, Issue:1 Topics: Adrenergic beta-Agonists; Aminophylline; Antitussive Agents; Bronchodilator Agents; Capsules; Chlorpheniramine; Chromatography, High Pressure Liquid; Drug Combinations; Indicators and Reagents; Methamphetamine; Noscapine; Reference Standards; Reproducibility of Results; Solutions; Spectrophotometry, Ultraviolet	2003
The use of noscapine (narcotine) as an antitussive agent. Diseases of the chest, 1957, Volume: 32, Issue:3 Topics: Antitussive Agents; Cough; Humans; Noscapine	1957
[The antitussive and bronchodilating properties of narcotine hydrochloride]. Archives internationales de pharmacodynamie et de therapie, 1959, Mar-01, Volume: 119, Issue:1-2 Topics: Antitussive Agents; Bronchi; Cell Respiration; Cough; Humans; Noscapine; Respiration	1959
[Therapeutic trial of the resinat of noscapine as an antitussive agent]. Jornal do medico, 1960, Dec-03, Volume: 43 Topics: Antacids; Antitussive Agents; Cough; Humans; Noscapine	1960
[Narcotine. A new antitussive medicament of great value in chronic pulmonary diseases]. Prensa medica argentina, 1961, Mar-10, Volume: 48 Topics: Antitussive Agents; Chronic Disease; Cough; Humans; Lung Diseases; Noscapine	1961
[Comparative antitussive effects of noscapine hydrochloride and dihydrocodeine bitartrate. Experiments made without the awareness of the subject. (Doppel-Blindversuch, double blind test)]. Praxis, 1962, Mar-22, Volume: 51 Topics: Antitussive Agents; Awareness; Blindness; Codeine; Cough; Double-Blind Method; Humans; Noscapine; Visually Impaired Persons	1962
[Ability of antitussives to modify the sneezing reflex]. Helvetica physiologica et pharmacologica acta, 1962, Volume: 20 Topics: Antitussive Agents; Codeine; Humans; Nervous System Physiological Phenomena; Noscapine; Reflex; Sneezing	1962
[Irritative cough]. Medizinische Monatsschrift, 1962, Volume: 16 Topics: Antitussive Agents; Bronchial Diseases; Codeine; Cough; Humans; Lung Diseases; Noscapine; Tuberculosis; Tuberculosis, Pulmonary	1962
[Apropos of a new antitussive agent, noscapine camphosulfonate (Tulisan). Its utility in pediatric therapeutics]. Gazette medicale de France, 1962, Nov-10, Volume: 69 Topics: Antitussive Agents; Child; Humans; Noscapine; Pediatrics	1962
[CLINICAL TRIALS WITH A NARCOTINE-CONTAINING ANTITUSSIVE AGENT]. Therapeutische Umschau. Revue therapeutique, 1963, Volume: 20 Topics: Antitussive Agents; Humans; Noscapine	1963
ANTITUSSIVE ACTIVITY OF A NEW LOCAL ANESTHETIC COMPOUND: BENZOBUTAMINE. Nature, 1963, Aug-31, Volume: 199 Topics: Anesthetics; Anesthetics, Local; Antitussive Agents; Codeine; Dogs; Guinea Pigs; Noscapine; Pharmacology; Phenobarbital; Rabbits; Rats; Research; Toxicology	1963
TO-DAYS DRUGS. COUGH SUPPRESSANTS. British medical journal, 1964, May-02, Volume: 1, Issue:5391 Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antitussive Agents; Codeine; Heroin; Humans; Ion Exchange Resins; Methadone; Noscapine; Parasympatholytics; Pharmacology	1964
ANTITUSSIVE ACTIVITY OF NARCOTINE DERIVATIVES. Chemical & pharmaceutical bulletin, 1964, Volume: 12 Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antitussive Agents; Anura; Blood Pressure; Guinea Pigs; Muscle Contraction; Noscapine; Pharmacology; Rabbits; Research; Respiration; Toxicology	1964
Reduction of the prenatal hypoxic-ischemic brain edema with noscapine. Acta physiologica Hungarica, 2003, Volume: 90, Issue:4 Topics: Animals; Antitussive Agents; Basal Ganglia; Brain Edema; Cerebral Cortex; Disease Models, Animal; Female; Fetus; Hypoxia-Ischemia, Brain; Male; Noscapine; Pregnancy; Rats	2003
Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-01, Volume: 10, Issue:15 Topics: Animals; Antineoplastic Agents; Antitussive Agents; Blood-Brain Barrier; Brain; Brain Neoplasms; Bromodeoxyuridine; Cattle; Cell Count; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Coloring Agents; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flow Cytometry; Glioblastoma; Humans; Image Processing, Computer-Assisted; Inhibitory Concentration 50; Mice; Mice, Nude; Mice, SCID; Microcirculation; Microtubules; Mitosis; Models, Biological; Neoplasm Transplantation; Neuroglia; Noscapine; Rats; S Phase; Time Factors; Tubulin	2004
Development and validation of a capillary electrophoresis method for the determination of codeine, diphenhydramine, ephedrine and noscapine in pharmaceuticals. Farmaco (Societa chimica italiana : 1989), 2005, Volume: 60, Issue:1 Topics: Antitussive Agents; Codeine; Diphenhydramine; Electrophoresis, Capillary; Ephedrine; Hydrogen-Ion Concentration; Noscapine; Reproducibility of Results	2005
Noscapine suppresses angiotensin converting enzyme inhibitors-induced cough. Nephrology (Carlton, Vic.), 2005, Volume: 10, Issue:4 Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antitussive Agents; Bradykinin; Cough; Female; Humans; Hypertension; Male; Middle Aged; Noscapine	2005
Synthesis and biological evaluation of a cyclic ether fluorinated noscapine analog. Bioorganic & medicinal chemistry, 2006, Dec-15, Volume: 14, Issue:24 Topics: Antibiotics, Antineoplastic; Antitussive Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Humans; Noscapine; Spindle Apparatus; Tumor Cells, Cultured	2006
Apoptotic pathway induced by noscapine in human myelogenous leukemic cells. Anti-cancer drugs, 2007, Volume: 18, Issue:10 Topics: Antitussive Agents; Apoptosis; Caspases; DNA Fragmentation; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid; Noscapine; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Tubulin Modulators	2007
A simple and rapid flow-injection chemiluminescence method for the determination of noscapine with Ru(phen)3(2+)-Ce(IV) system. Annali di chimica, 2007, Volume: 97, Issue:8 Topics: Antitussive Agents; Calibration; Cerium; Flow Injection Analysis; Luminescent Measurements; Noscapine; Organometallic Compounds; Phenanthrolines; Sensitivity and Specificity	2007
Simultaneous determination of codeine and noscapine by flow-injection chemiluminescence method using N-PLS regression. Journal of pharmaceutical and biomedical analysis, 2009, Feb-20, Volume: 49, Issue:2 Topics: Antitussive Agents; Calibration; Codeine; Electricity; Flow Injection Analysis; Kinetics; Luminescence; Luminescent Measurements; Noscapine; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity; Software; Sulfuric Acids; Time Factors	2009
[Noscapine and warfarin--a potentially dangerous interaction]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2009, Mar-12, Volume: 129, Issue:6 Topics: Anticoagulants; Antitussive Agents; Drug Interactions; Drug Synergism; Humans; International Normalized Ratio; Noscapine; Warfarin	2009
Potent anti-inflammatory activity of novel microtubule-modulating brominated noscapine analogs. PloS one, 2010, Feb-11, Volume: 5, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Antitussive Agents; Autophagy; Blotting, Western; Cell Line; Chemokine CXCL10; Dose-Response Relationship, Drug; Halogenation; Humans; Interleukin-8; Macrophages; Microscopy, Electron; Models, Biological; Molecular Structure; Nitric Oxide; Noscapine; Reactive Oxygen Species; Toll-Like Receptor 4; Tubulin Modulators; Tumor Necrosis Factor-alpha	2010
Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction. British journal of clinical pharmacology, 2010, Volume: 69, Issue:2 Topics: Adult; Anticoagulants; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Microsomes, Liver; Middle Aged; Models, Biological; Models, Chemical; Noscapine; Time Factors; Tissue Culture Techniques; Warfarin	2010
Prophylactic noscapine therapy inhibits human prostate cancer progression and metastasis in a mouse model. Anticancer research, 2010, Volume: 30, Issue:2 Topics: Animals; Antitussive Agents; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Humans; Lymphatic Metastasis; Male; Mice; Mice, Nude; Noscapine; Prostatic Neoplasms; Xenograft Model Antitumor Assays	2010
Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathway. Cancer research, 2010, Apr-15, Volume: 70, Issue:8 Topics: Alkaloids; Antitussive Agents; Benzylisoquinolines; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; I-kappa B Kinase; Jurkat Cells; Leukemia; Neoplasm Invasiveness; Neovascularization, Pathologic; NF-kappa B; Noscapine; Signal Transduction	2010
Validated stability-indicating TLC method for the determination of noscapine. Drug testing and analysis, 2009, Volume: 1, Issue:7 Topics: Antitussive Agents; Chromatography, Thin Layer; Densitometry; Drug Stability; Hydrogen-Ion Concentration; Hydrolysis; Noscapine; Oxidation-Reduction; Photolysis; Quality Control; Regression Analysis; Reproducibility of Results	2009
Evaluation of ligand-selector interaction from effective diffusion coefficient. Analytical chemistry, 2010, Jul-01, Volume: 82, Issue:13 Topics: Adrenergic beta-Antagonists; Animals; Anticoagulants; Antitussive Agents; Cattle; Chromatography, High Pressure Liquid; Cyclodextrins; Diffusion; Ligands; Nitrophenols; Noscapine; Pharmaceutical Preparations; Photosensitizing Agents; Propranolol; Riboflavin; Salicylic Acid; Serum Albumin, Bovine; Warfarin	2010
Enhanced noscapine delivery using uPAR-targeted optical-MR imaging trackable nanoparticles for prostate cancer therapy. Journal of controlled release : official journal of the Controlled Release Society, 2011, Feb-10, Volume: 149, Issue:3 Topics: Antineoplastic Agents; Antitussive Agents; Cell Line; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Humans; Magnetic Resonance Imaging; Male; Nanoparticles; Noscapine; Prostate; Prostatic Neoplasms; Receptors, Urokinase Plasminogen Activator	2011
Fixed drug eruption caused by noscapine. The Journal of dermatology, 2011, Volume: 38, Issue:3 Topics: Antitussive Agents; Common Cold; Drug Eruptions; Humans; Male; Middle Aged; Nonprescription Drugs; Noscapine; Thigh	2011
Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site. Journal of molecular graphics & modelling, 2011, Volume: 29, Issue:7 Topics: Animals; Antineoplastic Agents; Antitussive Agents; Binding Sites; Colchicine; Goats; Humans; Models, Chemical; Molecular Dynamics Simulation; Molecular Structure; Neoplasms; Noscapine; Protein Conformation; Tubulin	2011
Rational design, synthesis and biological evaluations of amino-noscapine: a high affinity tubulin-binding noscapinoid. Journal of computer-aided molecular design, 2011, Volume: 25, Issue:5 Topics: Antineoplastic Agents; Antitussive Agents; Binding Sites; Colchicine; Drug Design; Hydrogen Bonding; Ligands; Microtubules; Models, Chemical; Molecular Structure; Noscapine; Polymerization; Protein Binding; Thermodynamics; Tubulin	2011
Determination of noscapine's localization and interaction with the tubulin-α/β heterodimer. Chemical biology & drug design, 2011, Volume: 78, Issue:4 Topics: Antineoplastic Agents; Antitussive Agents; Binding Sites; Humans; Models, Molecular; Neoplasms; Noscapine; Protein Binding; Protein Multimerization; Tubulin	2011
Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer. PloS one, 2011, Volume: 6, Issue:11 Topics: Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antitussive Agents; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cells, Cultured; Deoxycytidine; Drug Synergism; Female; Gemcitabine; Human Umbilical Vein Endothelial Cells; Humans; Immunoenzyme Techniques; Lung Neoplasms; Mice; Mice, Nude; Neovascularization, Pathologic; Noscapine; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays	2011
Increased hypoxia-inducible factor 1α expression in lung cells of horses with recurrent airway obstruction. BMC veterinary research, 2012, May-23, Volume: 8 Topics: Animals; Antitussive Agents; Cells, Cultured; Dust; Gene Expression Regulation; Horse Diseases; Horses; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-8; Lung; Lung Diseases, Obstructive; Monocytes; Noscapine; RNA, Messenger; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A	2012
Noscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53. PloS one, 2012, Volume: 7, Issue:7 Topics: Antitussive Agents; Apoptosis; Caspase 3; Cell Line, Tumor; DNA Fragmentation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Neuroblastoma; Noscapine; Phosphorylation; RNA, Messenger; RNA, Neoplasm; Survivin; Tumor Suppressor Protein p53	2012
Synthesis and biological evaluation of N-substituted noscapine analogues. ChemMedChem, 2012, Volume: 7, Issue:12 Topics: Antineoplastic Agents, Phytogenic; Antitussive Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Neoplasms; Noscapine; Papaver	2012
Antifibrotic effects of noscapine through activation of prostaglandin E2 receptors and protein kinase A. The Journal of biological chemistry, 2014, Mar-14, Volume: 289, Issue:11 Topics: Animals; Antineoplastic Agents; Antitussive Agents; Bleomycin; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; DNA; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Hydroxyproline; Luciferases; Lung; Mice; Mice, Inbred C57BL; Microtubules; Myofibroblasts; Neoplasms; Noscapine; Pulmonary Fibrosis; Receptors, Prostaglandin E	2014
Enhanced noscapine delivery using estrogen-receptor-targeted nanoparticles for breast cancer therapy. Anti-cancer drugs, 2014, Volume: 25, Issue:6 Topics: Antineoplastic Agents; Antitussive Agents; Breast Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Estrone; Female; Gelatin; Humans; Inhibitory Concentration 50; Molecular Targeted Therapy; Nanoparticles; Noscapine; Protein Structure, Secondary; Receptors, Estrogen	2014
Epithelial transport of noscapine across cell monolayer and influence of absorption enhancers on in vitro permeation and bioavailability: implications for intestinal absorption. Journal of drug targeting, 2014, Volume: 22, Issue:6 Topics: Animals; Antitussive Agents; Biological Availability; Caco-2 Cells; Cells, Cultured; Chromatography, High Pressure Liquid; Dogs; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Noscapine; Rats; Rats, Sprague-Dawley; Solubility	2014
Noscapine Increases the Sensitivity of Drug-Resistant Ovarian Cancer Cell Line SKOV3/DDP to Cisplatin by Regulating Cell Cycle and Activating Apoptotic Pathways. Cell biochemistry and biophysics, 2015, Volume: 72, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antitussive Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Mice; Mice, Inbred BALB C; Noscapine; Ovarian Neoplasms; Xenograft Model Antitumor Assays	2015
Noscapine recirculates enterohepatically and induces self-clearance. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Sep-18, Volume: 77 Topics: Animals; Antitussive Agents; Food-Drug Interactions; Humans; Intestinal Mucosa; Liver; Male; Mice; Noscapine	2015
Noscapine: angioedema. Prescrire international, 2016, Volume: 25, Issue:169 Topics: Angioedema; Antitussive Agents; Humans; Noscapine	2016
Structural investigations into the binding mode of a novel noscapine analogue, 9-(4-vinylphenyl) noscapine, with tubulin by biochemical analyses and molecular dynamic simulations. Journal of biomolecular structure & dynamics, 2017, Volume: 35, Issue:11 Topics: Antitussive Agents; Humans; Microtubules; Models, Molecular; Molecular Dynamics Simulation; Noscapine; Protein Binding; Tubulin	2017
Design and optimization of noscapine nanosuspensions and study of its cytotoxic effect. Journal of biomolecular structure & dynamics, 2019, Volume: 37, Issue:1 Topics: Antitussive Agents; Cell Line; Cell Survival; Drug Delivery Systems; Humans; Nanoparticles; Noscapine	2019
Interaction of OTC drug noscapine and acenocoumarol and phenprocoumon. British journal of clinical pharmacology, 2019, Volume: 85, Issue:5 Topics: Acenocoumarol; Adult; Aged; Aged, 80 and over; Anticoagulants; Antitussive Agents; Cough; Drug Interactions; Female; Hemorrhage; Humans; International Normalized Ratio; Male; Middle Aged; Netherlands; Nonprescription Drugs; Noscapine; Phenprocoumon; Thromboembolism	2019
Noscapine protects the H9c2 cardiomyocytes of rats against oxygen-glucose deprivation/reperfusion injury. Molecular biology reports, 2020, Volume: 47, Issue:8 Topics: Animals; Antitussive Agents; Apoptosis; Cell Hypoxia; Cell Line; Cell Survival; Glucose; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Noscapine; Oxygen; Rats	2020
Antitussive noscapine and antiviral drug conjugates as arsenal against COVID-19: a comprehensive chemoinformatics analysis. Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:1 Topics: Antitussive Agents; Antiviral Agents; Cheminformatics; COVID-19; Humans; Molecular Docking Simulation; Noscapine; Protease Inhibitors; SARS-CoV-2	2022
Medical prescription forms of opioid cough suppressants falsified by the patients before and after they switched from over-the-counter to prescription-only in France. British journal of clinical pharmacology, 2022, Volume: 88, Issue:4 Topics: Analgesics, Opioid; Antitussive Agents; Codeine; Cough; Dextromethorphan; Ethylmorphine; Female; Humans; Male; Nonprescription Drugs; Noscapine; Prescriptions	2022
Noscapine alleviates unilateral ureteral obstruction-induced inflammation and fibrosis by regulating the TGFβ1/Smads signaling pathways. Biochimica et biophysica acta. Molecular cell research, 2024, Volume: 1871, Issue:1 Topics: Animals; Antitussive Agents; Fibrosis; Inflammation; Kidney Diseases; Mice; Noscapine; Signal Transduction; Transforming Growth Factor beta1; Ureteral Obstruction	2024