Page last updated: 2024-08-20

diphenhydramine hydrochloride and dihydrocodeine

diphenhydramine hydrochloride has been researched along with dihydrocodeine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19908 (32.00)18.7374
1990's11 (44.00)18.2507
2000's4 (16.00)29.6817
2010's2 (8.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gräber, U; Matthys, H; Rühle, KH1
Kamei, J; Kasuya, Y1
Igarashi, H; Kamei, J; Kasuya, Y; Mori, T1
Kamei, J; Kasuya, Y; Mori, T2
Fukagawa, Y; Masukawa, Y; Misawa, M; Suzuki, T; Yanaura, S; Yoshii, T1
Masukawa, Y; Misawa, M; Suzuki, T1
Kamei, J; Kasuya, Y; Mori, T; Ogawa, M1
Kamei, J; Kasuya, Y; Ogawa, M1
Koike, Y; Misawa, M; Suzuki, T; Yanaura, S; Yoshida, E; Yoshii, T1
Erhardt, J; Matthys, H; Rühle, KH1
Kigoshi, S; Kokubo, M; Nishio, M1
Kirkwood, LC; Nation, RL; Somogyi, AA1
Kamei, J; Kashiwazaki, T; Morita, K; Ohsawa, M1
Barni, S; Daffonchio, L; Luporini, G; Marchi, E1
Kamei, J; Morita, K; Ohsawa, M; Onodera, K1
Wu, Y1
Kamei, J; Morita, K; Onodera, K1
Kamei, J; Miyata, S; Morita, K; Onodera, K1
AGUET, F; BARASZ, Z; BONSTEIN, H; FAVEZ, G1
HOWARD, HI1
Manabe, H; Murao, S; Sekikawa, T; Yamashita, T1
Karamanakos, PN1
Ameno, K; Jamal, M; Kinoshita, H; Kumihashi, M; Okuzono, R; Tanaka, N1
Fontana, G; Lanata, L; Lavorini, F; Mannini, C; Saibene, F; Zanasi, A1

Trials

4 trial(s) available for diphenhydramine hydrochloride and dihydrocodeine

ArticleYear
[Comparison of the antitussive effect of two different drugs regarding frequency and strength of cough attacks (author's transl)].
    Medizinische Klinik, 1977, Nov-25, Volume: 72, Issue:47

    Topics: Adult; Aged; Antitussive Agents; Benzhydryl Compounds; Codeine; Cough; Drug Evaluation; Ethylamines; Female; Humans; Male; Middle Aged; Time Factors

1977
[Objectivation of the effect of antitussive agents using tussometry in patients with chronic cough].
    Schweizerische medizinische Wochenschrift, 1985, Mar-02, Volume: 115, Issue:9

    Topics: Adult; Aged; Antitussive Agents; Bronchitis; Carcinoma, Bronchogenic; Chronic Disease; Clinical Trials as Topic; Codeine; Cough; Dextromethorphan; Double-Blind Method; Humans; Lung Neoplasms; Middle Aged; Noscapine; Tuberculosis, Pulmonary

1985
Efficacy and safety of levodropropizine and dihydrocodeine on nonproductive cough in primary and metastatic lung cancer.
    The European respiratory journal, 1998, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Antitussive Agents; Codeine; Cough; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Male; Middle Aged; Propylene Glycols; Treatment Outcome

1998
A Randomized Clinical Trial Comparing the Effects of Antitussive Agents on Respiratory Center Output in Patients With Chronic Cough.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Adult; Aged; Antitussive Agents; Chronic Disease; Codeine; Cough; Cross-Over Studies; Female; Humans; Hypercapnia; Male; Middle Aged; Propylene Glycols; Respiratory Center; Respiratory Insufficiency; Respiratory Rate; Single-Blind Method

2017

Other Studies

21 other study(ies) available for diphenhydramine hydrochloride and dihydrocodeine

ArticleYear
Antitussive effects of Ca2+ channel antagonists.
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: Animals; Antitussive Agents; Calcium Channel Blockers; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Drug Synergism; Flunarizine; Guinea Pigs; Male; Morphine; Nifedipine; Verapamil

1992
Effects of 8-hydroxy-2-(di-n-propylamino)tetralin, a selective agonist of 5-HT1A receptors, on the cough reflex in rats.
    European journal of pharmacology, 1991, Oct-15, Volume: 203, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Dextromethorphan; Drug Interactions; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex; Tetrahydronaphthalenes

1991
Effects of L-tryptophan on the development of tolerance to the antitussive effects of dihydrocodeine.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:3

    Topics: Animals; Antitussive Agents; Codeine; Cough; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; Male; Rats; Rats, Inbred Strains; Reflex; Trachea; Tryptophan

1991
[The effects of constituents of an antitussive and expectorant preparation on physical dependence on and antitussive activity of dihydrocodeine].
    Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence, 1990, Volume: 25, Issue:5

    Topics: Animals; Antitussive Agents; Codeine; Cough; Drug Synergism; Drug Therapy, Combination; Expectorants; Guinea Pigs; Histamine H1 Antagonists; Male; Rats; Rats, Inbred Strains; Substance-Related Disorders

1990
Drug interactions in the reinforcing effects of over-the-counter cough syrups.
    Psychopharmacology, 1990, Volume: 102, Issue:4

    Topics: Animals; Antitussive Agents; Benzazepines; Chlorpheniramine; Codeine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Morphine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Substance-Related Disorders

1990
Effects of L-tryptophan on the effects of antitussives.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:4

    Topics: Animals; Antitussive Agents; Brain; Codeine; Dextromethorphan; Drug Interactions; Male; Noscapine; Rats; Rats, Inbred Strains; Serotonin; Substance-Related Disorders; Tryptophan

1990
Subsensitivity to the cough-depressant effects of opioid and nonopioid antitussives in morphine-dependent rats: relationship to central serotonin function.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:3

    Topics: Animals; Antitussive Agents; Brain Stem; Codeine; Cough; Dextromethorphan; Levorphanol; Male; Morphine; Noscapine; Rats; Rats, Inbred Strains; Receptors, Serotonin

1989
Supersensitivity of 5,7-dihydroxytryptamine-treated rats to the respiratory depressant and antitussive effects of dihydrocodeine.
    European journal of pharmacology, 1988, Aug-24, Volume: 153, Issue:2-3

    Topics: 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Antitussive Agents; Brain; Codeine; Cough; Dihydroxytryptamines; Drug Synergism; Female; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Respiration; Serotonin

1988
[The effects of noscapine and chlorpheniramine on physical dependence and antitussive activity of dihydrocodeine].
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1988, Volume: 8, Issue:2

    Topics: Animals; Antitussive Agents; Body Weight; Chlorpheniramine; Codeine; Drug Interactions; Guinea Pigs; Male; Noscapine; Rats; Rats, Inbred Strains; Substance-Related Disorders

1988
Effect of the centrally acting antitussives on ascites tumor cells.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:2

    Topics: Animals; Antineoplastic Agents; Antitussive Agents; Carcinoma, Ehrlich Tumor; Cell Survival; Cells, Cultured; Codeine; Dextromethorphan; Female; Mice; Morphinans; Sarcoma 180; Thebaine

1983
Determination of the dihydrocodeine metabolites, dihydromorphine and nordihydrocodeine, in hepatic microsomal incubations by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Nov-07, Volume: 701, Issue:1

    Topics: Analgesics, Opioid; Animals; Antitussive Agents; Chromatography, High Pressure Liquid; Codeine; Cytochrome P-450 CYP2D6; Dihydromorphine; Humans; In Vitro Techniques; Microsomes, Liver; Oxidation-Reduction; Rats; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

1997
Antitussive effect of moguisteine on allergic coughs in the guinea pig.
    European journal of pharmacology, 1998, Apr-24, Volume: 347, Issue:2-3

    Topics: Analgesics, Opioid; Animals; Antitussive Agents; Codeine; Cough; Disease Models, Animal; Guinea Pigs; Hypersensitivity; Male; Thiazoles; Thiazolidines

1998
Effects of epinastine on the antitussive and rewarding effects of dihydrocodeine in mice.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:10

    Topics: Animals; Antitussive Agents; Chlorpheniramine; Codeine; Conditioning, Operant; Cough; Dibenzazepines; Drug Synergism; Histamine H1 Antagonists; Imidazoles; Male; Mice; Mice, Inbred ICR; Reward

1999
[Studies on the analysis of hydrocodone and its metabolite in human urine by GC/MS].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:4

    Topics: Analgesics, Opioid; Antitussive Agents; Codeine; Gas Chromatography-Mass Spectrometry; Humans; Hydrocodone

1997
Inhaled pinacidil, an ATP-sensitive K+ channel opener, and moguisteine have potent antitussive effects in guinea pigs.
    Japanese journal of pharmacology, 2002, Volume: 89, Issue:2

    Topics: Adenosine Triphosphate; Administration, Inhalation; Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Dose-Response Relationship, Drug; Drug Antagonism; Glyburide; Guinea Pigs; Male; Naloxone; Pinacidil; Potassium Channels; Thiazoles; Thiazolidines

2002
Effects of second generation of histamine H1 antagonists, cetirizine and ebastine, on the antitussive and rewarding effects of dihydrocodeine in mice.
    Psychopharmacology, 2003, Volume: 166, Issue:2

    Topics: Animals; Antitussive Agents; Butyrophenones; Cetirizine; Codeine; Dopamine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Limbic System; Male; Mice; Mice, Inbred ICR; Piperidines; Receptors, Dopamine D1; Reward

2003
[Comparative antitussive effects of noscapine hydrochloride and dihydrocodeine bitartrate. Experiments made without the awareness of the subject. (Doppel-Blindversuch, double blind test)].
    Praxis, 1962, Mar-22, Volume: 51

    Topics: Antitussive Agents; Awareness; Blindness; Codeine; Cough; Double-Blind Method; Humans; Noscapine; Visually Impaired Persons

1962
DIHYDROCODEINE AS A COUGH SUPPRESSANT.
    The Practitioner, 1964, Volume: 193

    Topics: Antitussive Agents; Codeine; Humans

1964
Intoxication with over-the-counter antitussive medication containing dihydrocodeine and chlorpheniramine causes generalized convulsion and mixed acidosis.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:11

    Topics: Acidosis; Adult; Antitussive Agents; Chlorpheniramine; Codeine; Ephedrine; Humans; Japan; Male; Nonprescription Drugs; Seizures; Substance-Related Disorders

2008
Intoxication with over-the-counter antitussive medication containing dihydrocodeine and chlorpheniramine causes generalized convulsion and mixed acidosis.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:20

    Topics: Acidosis; Adult; Animals; Antitussive Agents; Chlorpheniramine; Codeine; Dose-Response Relationship, Drug; Drug Overdose; Humans; Male; Mice; Models, Animal; Nonprescription Drugs; Rats; Seizures; Serotonin 5-HT1 Receptor Agonists

2008
A fatal case due to cough syrup abuse.
    Soudni lekarstvi, 2012, Volume: 57, Issue:4

    Topics: Adult; Antitussive Agents; Chlorpheniramine; Codeine; Female; Humans

2012