diphenhydramine hydrochloride and dextrorphan

diphenhydramine hydrochloride has been researched along with dextrorphan in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (7.32)	18.7374
1990's	19 (46.34)	18.2507
2000's	14 (34.15)	29.6817
2010's	5 (12.20)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Emele, JF; Ramachander, G; Williams, FD	1
Choi, DW; Coulter, DA; Prince, DA; Wong, BY	1
Domino, EF; Krutak-Krol, H; Lal, J	1
Braga, PC; Caputo, R; Fossati, A; Guffanti, EE; Vimercati, MG	1
Chai, CK; Demirbas, S; Reyderman, L; Stavchansky, S	1
Baragatti, G; Dematteis, M; Gavend, M; Mallaret, M	1
Jäger, W; Klinger, P; Mayrhofer, A; Spatzenegger, M; Vielnascher, E	1
Ishii, M; Kaneko, F; Kawakubo, T; Nagai, N; Ogata, H; Ohnishi, A; Saito, Y; Shimamura, H; Shinohara, R	1
Caputo, R; Fossati, A; Valenti, M; Vimercati, MG	1
Löscher, W; Richter, A	1
Darj, E; Frenne, G; Rane, A; Wadelius, M	1
Baubichon, D; Dematteis, M; Lallement, G; Mallaret, M; Pernot-Marino, I	1
Eichhold, TH; Greenfield, LJ; Hoke, SH; Wehmeyer, KR	1
Eddington, NE; Leslie, J; Mistry, B	1
Chang, WH; Hu, OY; Hu, TM; Lane, HY; Tang, HS	1
Dematteis, M; Lallement, G; Mallaret, M	1
Franklin, PH; Ishmael, JE; Murray, TF	1
Chang, WY; Chen, CF; Chou, YC; Liao, JF; Lin, MF	1
Abdel-Rahman, SM; Gotschall, RR; Kauffman, RE; Kearns, GL; Leeder, JS	1
Li, NY; Li, Y; Messina, E; Miksys, S; Sellers, EM; Tyndale, RF	1
Bertino, JS; Ellis, RE; Gaedigk, A; Gotschall, R; Kearns, GL; Leeder, JS; Nafziger, AN; Streetman, DS	1
Unadkat, JD; Wang, Y	1
Bailey, B; Daneman, N; Daneman, R; Koren, G; Mayer, JM	1
Bertolino, M; Caruso, FS; Hernandez, SC; Kellar, KJ; Pringle, KE; Xiao, Y	1
Haining, RL; Yu, A	1
Abdul-Manap, R; Moghadamnia, AA; Morice, AH; Rostami-Hodjegan, A; Tucker, GT; Wright, CE	1
Kukanich, B; Papich, MG	1
Chavez-Eng, CM; Constanzer, ML; Fu, I; Matuszewski, BK; Woolf, EJ	1
Baker, TR; Eichold, TH; Hoke, SH; Kuhlenbeck, DL; Mensen, R; Wehmeyer, KR	1
Miller, SC	1
Choi, SK; Chung, HS; Kim, EM; Lee, JS; Lim, MA; Park, MJ	1
Eichhold, TH; Hoke, SH; Khambe, DA; McCauley-Myers, DL; Thompson, GA	1
Dickinson, GL; Lennard, MS; Proctor, NJ; Rezaee, S; Rostami-Hodjegan, A; Tucker, GT	1
Agrawal, A; Moore, C; Rodrigues, WC; Soares, JR; Vincent, MJ; Wang, G	1
Krishna, DR; Prasad, KV; Prasanthi, S; Vidyavathi, M	1
Mironidou-Tzouveleki, M; Niopas, I; Spanakis, M; Vizirianakis, IS	1
Abduljalil, K; Frank, D; Fuhr, U; Gaedigk, A; Jaehde, U; Jetter, A; Kirchheiner, J; Klaassen, T; Tomalik-Scharte, D	1
Dorado, P; Heras, N; Hernández, F; Llerena, A; Machín, E; Teran, E	1
Beijnen, JH; Goey, AK; Meijerman, I; Schellens, JH	1
Berk, D; Chen, R; Hu, P; Rostami-Hodjegan, A; Shi, J; Wang, H	1
Corado, CR; Knych, HK; McKemie, DS	1

Reviews

1 review(s) available for diphenhydramine hydrochloride and dextrorphan

Article	Year
Discriminative stimulus properties of dextromethorphan in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1995, Volume: 49, Issue:10 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antitussive Agents; Cyclazocine; Cyclopentanes; Dextromethorphan; Dextrorphan; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Morphine; Neuroprotective Agents; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, sigma	1995

Article

Year

Discriminative stimulus properties of dextromethorphan in rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1995, Volume: 49, Issue:10

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antitussive Agents; Cyclazocine; Cyclopentanes; Dextromethorphan; Dextrorphan; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Morphine; Neuroprotective Agents; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, sigma

1995

Trials

9 trial(s) available for diphenhydramine hydrochloride and dextrorphan

Article	Year
Pharmacokinetics and polymorphic oxidation of dextromethorphan in a Japanese population. Biopharmaceutics & drug disposition, 1996, Volume: 17, Issue:5 Topics: Administration, Oral; Adult; Antitussive Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Female; Humans; Japan; Male; Oxidation-Reduction; Phenotype; Polymorphism, Genetic; Reference Standards	1996
Determination of dextromethorphan and dextrorphan in human plasma by liquid chromatography/tandem mass spectrometry. Journal of mass spectrometry : JMS, 1997, Volume: 32, Issue:11 Topics: Adult; Antitussive Agents; Calibration; Chromatography, High Pressure Liquid; Dextromethorphan; Dextrorphan; Excitatory Amino Acid Antagonists; Freezing; Humans; Male; Mass Spectrometry; Solutions	1997
Investigation of terbinafine as a CYP2D6 inhibitor in vivo. Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:5 Topics: Adult; Antifungal Agents; Antitussive Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Dextrorphan; Enzyme Inhibitors; Female; Humans; Male; Naphthalenes; Phenotype; Prospective Studies; Reference Values; Terbinafine; Volunteers	1999
Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping. Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:5 Topics: Adult; Alleles; Antitussive Agents; Cross-Over Studies; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Phenotype	1999
Physiologically based modelling of inhibition of metabolism and assessment of the relative potency of drug and metabolite: dextromethorphan vs. dextrorphan using quinidine inhibition. British journal of clinical pharmacology, 2003, Volume: 56, Issue:1 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adult; Antitussive Agents; Cough; Cross-Over Studies; Dextromethorphan; Dextrorphan; Double-Blind Method; Female; Humans; Male; Quinidine	2003
Plasma profile and pharmacokinetics of dextromethorphan after intravenous and oral administration in healthy dogs. Journal of veterinary pharmacology and therapeutics, 2004, Volume: 27, Issue:5 Topics: Administration, Oral; Animals; Antitussive Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Dextromethorphan; Dextrorphan; Dogs; Female; Injections, Intravenous; Male; Muscle, Skeletal; Receptors, N-Methyl-D-Aspartate	2004
Simultaneous determination of dextromethorphan, dextrorphan, and guaifenesin in human plasma using semi-automated liquid/liquid extraction and gradient liquid chromatography tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2007, Jan-17, Volume: 43, Issue:2 Topics: Administration, Oral; Antitussive Agents; Autoanalysis; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cross-Over Studies; Dextromethorphan; Dextrorphan; Double-Blind Method; Drug Combinations; Drug Stability; Drug Storage; Expectorants; Guaifenesin; Guidelines as Topic; Humans; Linear Models; Reference Standards; Reference Values; Reproducibility of Results; Tandem Mass Spectrometry	2007
Development and validation of ELISA and GC-MS procedures for the quantification of dextromethorphan and its main metabolite dextrorphan in urine and oral fluid. Journal of analytical toxicology, 2008, Volume: 32, Issue:3 Topics: Antitussive Agents; Dextromethorphan; Dextrorphan; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Illicit Drugs; Saliva	2008
The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteers. European journal of clinical pharmacology, 2013, Volume: 69, Issue:11 Topics: Adult; Antitussive Agents; Cross-Over Studies; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Drug Interactions; Female; Grape Seed Extract; Healthy Volunteers; Humans; Male; Middle Aged; Young Adult	2013

Other Studies

31 other study(ies) available for diphenhydramine hydrochloride and dextrorphan

Article	Year
Effect of salicylamide and acetaminophen on dextromethorphan hydrobromide metabolism: possible pharmacological implications. Journal of pharmaceutical sciences, 1978, Volume: 67, Issue:6 Topics: Acetaminophen; Animals; Antitussive Agents; Dextromethorphan; Dextrorphan; Dogs; Drug Interactions; Female; Levorphanol; Rats; Salicylamides; Time Factors	1978
Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices. Neuroscience letters, 1988, Feb-29, Volume: 85, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Antitussive Agents; Aspartic Acid; Cerebral Cortex; Dextromethorphan; Dextrorphan; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Levorphanol; Morphinans; N-Methylaspartate; Seizures; Valine	1988
Comparative antitussive effects of dextrorphan, dextromethorphan and phencyclidine. Arzneimittel-Forschung, 1986, Volume: 36, Issue:7 Topics: Animals; Antitussive Agents; Cats; Cough; Decerebrate State; Dextromethorphan; Dextrorphan; Female; Levorphanol; Morphinans; Phencyclidine	1986
Dextrorphan and dextromethorphan: comparative antitussive effects on guinea pigs. Drugs under experimental and clinical research, 1994, Volume: 20, Issue:5 Topics: Animals; Antitussive Agents; Cough; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Guinea Pigs	1994
Simultaneous determination of dextrorphan and guaifenesin in human plasma by liquid chromatography with fluorescence detection. Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:7 Topics: Administration, Oral; Antitussive Agents; Biological Availability; Chromatography, Liquid; Delayed-Action Preparations; Dextrorphan; Drug Stability; Expectorants; Fluorescence; Guaifenesin; Humans; Hydrolysis; Male; Reproducibility of Results	1995
Metabolism of dextromethorphan in human liver microsomes: a rapid HPCL assay to monitor cytochrome P450 2D6 activity. Die Pharmazie, 1996, Volume: 51, Issue:8 Topics: Adult; Aged; Antitussive Agents; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Dealkylation; Dextromethorphan; Dextrorphan; Excitatory Amino Acid Antagonists; Female; Humans; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Spectrophotometry, Ultraviolet	1996
Pharmacological profile of dextrorphan. Arzneimittel-Forschung, 1995, Volume: 45, Issue:11 Topics: Administration, Oral; Animals; Anticonvulsants; Antitussive Agents; Behavior, Animal; Catalepsy; Cough; Dextromethorphan; Dextrorphan; Electric Stimulation; Female; Guinea Pigs; Injections, Intravenous; Male; Mice; Motor Activity; Postural Balance; Rats; Rats, Sprague-Dawley; Sleep; Vagus Nerve	1995
Dextrorphan, but not dextromethorphan, exerts weak antidystonic effects in mutant dystonic hamsters. Brain research, 1997, Jan-16, Volume: 745, Issue:1-2 Topics: Animals; Antitussive Agents; Cricetinae; Dextromethorphan; Dextrorphan; Disease Progression; Dystonia; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Receptors, sigma	1997
Induction of CYP2D6 in pregnancy. Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:4 Topics: Adult; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextrorphan; DNA; Enzyme Induction; Female; Genotype; Humans; Oxidoreductases, N-Demethylating; Phenotype; Pregnancy	1997
Evaluation of dextromethorphan and dextrorphan as a preventive treatment of soman toxicity in mice. Neuroscience letters, 1997, Oct-03, Volume: 234, Issue:2-3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anticonvulsants; Antitussive Agents; Dextromethorphan; Dextrorphan; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Mice; Neuroprotective Agents; Soman	1997
A sensitive assay of metoprolol and its major metabolite alpha-hydroxy metoprolol in human plasma and determination of dextromethorphan and its metabolite dextrorphan in urine with high performance liquid chromatography and fluorometric detection. Journal of pharmaceutical and biomedical analysis, 1998, Volume: 16, Issue:6 Topics: Adrenergic beta-Antagonists; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Dextrorphan; Humans; Indicators and Reagents; Metoprolol; Neuroprotective Agents; Quality Control; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence	1998
Novel single-point plasma or saliva dextromethorphan method for determining CYP2D6 activity. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3 Topics: Adult; Antitussive Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Excitatory Amino Acid Antagonists; Humans; Male; Phenotype; Saliva	1998
Dextromethorphan and dextrorphan in rats: common antitussives--different behavioural profiles. Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:5 Topics: Animals; Antitussive Agents; Ataxia; Cues; Dextromethorphan; Dextrorphan; Male; Maze Learning; Memory; Motor Activity; Rats; Rats, Wistar; Stereotyped Behavior	1998
Dextrorotatory opioids induce stereotyped behavior in Sprague-Dawley and Dark Agouti rats. Psychopharmacology, 1998, Volume: 140, Issue:2 Topics: Alcohol Oxidoreductases; Animals; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dealkylation; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Species Specificity; Stereotyped Behavior	1998
Binding of dimemorfan to sigma-1 receptor and its anticonvulsant and locomotor effects in mice, compared with dextromethorphan and dextrorphan. Brain research, 1999, Mar-13, Volume: 821, Issue:2 Topics: Animals; Anticonvulsants; Antitussive Agents; Behavior, Animal; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Electroshock; Locomotion; Male; Mice; Morphinans; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Phencyclidine; Receptors, sigma; Sigma-1 Receptor	1999
Characterization of cytochrome P-450 2D1 activity in rat brain: high-affinity kinetics for dextromethorphan. Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:8 Topics: Alcohol Oxidoreductases; Animals; Antibodies, Blocking; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Brain; Cerebellum; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dextromethorphan; Dextrorphan; Kinetics; Liver; Male; Membranes; NADP; Neuroprotective Agents; Rats; Rats, Wistar	1999
Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes. Biopharmaceutics & drug disposition, 1999, Volume: 20, Issue:7 Topics: Antibodies, Blocking; Antitussive Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Dextromethorphan; Dextrorphan; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Microsomes, Liver; Mixed Function Oxygenases	1999
Discrepancy between CYP2D6 phenotype and genotype derived from post-mortem dextromethorphan blood level. Forensic science international, 2000, May-08, Volume: 110, Issue:1 Topics: Animals; Antitussive Agents; Cause of Death; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Excitatory Amino Acid Antagonists; Genotype; Humans; Infant; Male; Phenotype; Pneumonia; Rats; Rats, Wistar; Tissue Distribution	2000
Dextromethorphan and its metabolite dextrorphan block alpha3beta4 neuronal nicotinic receptors. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:3 Topics: Animals; Antitussive Agents; Cells, Cultured; Dextromethorphan; Dextrorphan; Humans; Nicotinic Antagonists; Rats; Receptors, N-Methyl-D-Aspartate; Rubidium Radioisotopes	2000
Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities? Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:11 Topics: Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextrorphan; Humans; Isoenzymes; Microsomes, Liver; Oxidoreductases, N-Demethylating	2001
Determination of dextromethorphan and its metabolite dextrorphan in human urine using high performance liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry: a study of selectivity of a tandem mass spectrometric assa Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Feb-25, Volume: 816, Issue:1-2 Topics: Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Dextrorphan; Drug Stability; Freezing; Humans; Mass Spectrometry; Reproducibility of Results	2005
On-line solid phase extraction using the Prospekt-2 coupled with a liquid chromatography/tandem mass spectrometer for the determination of dextromethorphan, dextrorphan and guaifenesin in human plasma. European journal of mass spectrometry (Chichester, England), 2005, Volume: 11, Issue:2 Topics: Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Dextrorphan; Expectorants; Guaifenesin; Humans; Spectrometry, Mass, Electrospray Ionization	2005
Dextromethorphan psychosis, dependence and physical withdrawal. Addiction biology, 2005, Volume: 10, Issue:4 Topics: Adult; Analgesics, Opioid; Antitussive Agents; Delusions; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Drug Tolerance; Female; Hallucinations; Humans; Nonprescription Drugs; Psychoses, Substance-Induced; Receptors, sigma; Recurrence; Substance Withdrawal Syndrome; Substance-Related Disorders	2005
Standardization of method for the analysis of dextromethorphan in urine. Forensic science international, 2006, Sep-12, Volume: 161, Issue:2-3 Topics: Adult; Antitussive Agents; Dextromethorphan; Dextrorphan; Female; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Molecular Structure; Substance Abuse Detection	2006
Incorporating in vitro information on drug metabolism into clinical trial simulations to assess the effect of CYP2D6 polymorphism on pharmacokinetics and pharmacodynamics: dextromethorphan as a model application. Journal of clinical pharmacology, 2007, Volume: 47, Issue:2 Topics: Antitussive Agents; Clinical Trials as Topic; Computer Simulation; Cough; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Models, Biological; Polymorphism, Genetic	2007
O-demethylation of dextromethorphan using microbial cultures. Drug metabolism letters, 2009, Volume: 3, Issue:1 Topics: Antitussive Agents; Bacteria; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Dealkylation; Dextromethorphan; Dextrorphan; Fungi; Humans; Magnetic Resonance Spectroscopy; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Stereoisomerism	2009
A validated SIM GC/MS method for the simultaneous determination of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in biological matrices and its application to in vitro CYP2D6 and CYP3A4 inhibition study. Biomedical chromatography : BMC, 2009, Volume: 23, Issue:11 Topics: Antitussive Agents; Calibration; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dextromethorphan; Dextrorphan; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Sensitivity and Specificity	2009
Assessment of activity levels for CYP2D61, CYP2D62, and CYP2D641 genes by population pharmacokinetics of dextromethorphan. Clinical pharmacology and therapeutics, 2010, Volume: 88, Issue:5* Topics: Administration, Oral; Adult; Antitussive Agents; Biotransformation; Clinical Trials as Topic; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Gene Frequency; Genotype; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Models, Biological; Phenotype; Polymorphism, Genetic; White People; Young Adult	2010
CYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population. European journal of clinical pharmacology, 2012, Volume: 68, Issue:5 Topics: Adolescent; Adult; Alleles; Antitussive Agents; Biotransformation; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Ecuador; Female; Gene Dosage; Gene Frequency; Genetic Association Studies; Humans; Hydroxylation; Male; Polymorphism, Genetic; Young Adult	2012
Application of a physiologically based pharmacokinetic model for the evaluation of single-point plasma phenotyping method of CYP2D6. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Sep-20, Volume: 92 Topics: Adult; Antitussive Agents; Area Under Curve; Asian People; Computer Simulation; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Female; Humans; Male; Middle Aged; Models, Biological; Phenotype; Young Adult	2016
Pharmacokinetics of dextromethorphan and its metabolites in horses following a single oral administration. Drug testing and analysis, 2017, Volume: 9, Issue:6 Topics: Administration, Oral; Animals; Antitussive Agents; Chromatography, Liquid; Dextromethorphan; Dextrorphan; Drug Monitoring; Excitatory Amino Acid Antagonists; Female; Glucuronides; Horses; Male; Mass Spectrometry	2017