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diphenhydramine hydrochloride and cyclopentane

diphenhydramine hydrochloride has been researched along with cyclopentane in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199020 (55.56)18.7374
1990's7 (19.44)18.2507
2000's5 (13.89)29.6817
2010's3 (8.33)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Chou, DT; Wallenstein, MC; Wang, SC1
Annels, SJ; Davies, JA; Ellis, Y1
Apland, JP; Braitman, DJ1
Braitman, DJ; Brennecke, LH; Sparenborg, S1
Musacchio, JM; Tortella, FC; Witkin, JM1
Moeller, H; Sieverding, L; Stier, BJ1
Regosz, A; Weclawska, K1
Musacchio, JM; Tortella, FC1
Ma, WL; Nie, LH; Yao, SZ; Zhu, AX1
Domino, EF; Krutak-Krol, H; Lal, J1
Heurich, AE; Sanzari, NP; Shepherd, DA; Thomas, J1
Razdan, BK; Sugden, JK1
Krieger, E1
Fujita, T; Sato, T1
Flanagan, T; Levandoski, P1
Diana, G; Pezzola, A; Popoli, P; Sagratella, S; Scotti de Carolis, A1
Calderon, SN; Gutkind, JS; Heller, B; Izenwasser, S; Mattson, MV; Newman, AH; Su, TP1
Domenici, MR; Frank, C; Sagratella, S; Scotti de Carolis, A1
Baragatti, G; Dematteis, M; Gavend, M; Mallaret, M1
Hattori, F; Inoue, N; Matsui, A; Matsuo, H; Nasu, R; Ohtani, H; Sawada, Y; Takanaga, H1
Hu, Y; Nie, L; Yao, S; Yuan, J1
SNYDER, GG1
PARISH, FA1
PLISNIER, H1
CASS, LJ; FREDERIK, WS1
ARCHIBALD, DW; SHANE, SJ; SLIPP, LB1
TARTARO, SM1
ROBIN, BA1
ELLIS, GP; GOLBERG, L; KING, J; SHEARD, P1
Beitz, AJ; Han, HJ; Kim, HW; Kim, KW; Kwon, YB; Lee, JH; Roh, DH; Seo, HS; Yoon, SY1
Ahrens, N; Deisemann, H; Kirchhoff, C; Möller, C; Netzer, R; Schlobohm, I1
Honda, S; Kawaura, K; Miki, R; Shima, E; Shirasaki, T; Soeda, F; Takahama, K1
Junge, T; Radünz, L; Rochholz, G; Stegk, J; Westphal, F1
Elfeky, SA; Issa, YM; Mohamed, SH1
Abo Dena, AS; Ali, AM; El-Sherbiny, IM1

Reviews

2 review(s) available for diphenhydramine hydrochloride and cyclopentane

ArticleYear
Some biological aspects of cyclopentane chemistry.
    Pharmaceutica acta Helvetiae, 1972, Volume: 47, Issue:5

    Topics: Analgesics; Antihypertensive Agents; Antineoplastic Agents; Antitussive Agents; Central Nervous System; Chromatography, Gas; Cyclopentanes; Insecticides; Mycobacterium; Parasympatholytics; Prostaglandins; Staphylococcus; Structure-Activity Relationship

1972
Discriminative stimulus properties of dextromethorphan in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1995, Volume: 49, Issue:10

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antitussive Agents; Cyclazocine; Cyclopentanes; Dextromethorphan; Dextrorphan; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Morphine; Neuroprotective Agents; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, sigma

1995

Trials

1 trial(s) available for diphenhydramine hydrochloride and cyclopentane

ArticleYear
A system for the clinical assessment of the antitussive activity of caramiphen.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:10

    Topics: Adult; Aged; Antitussive Agents; Bronchitis; Carboxylic Acids; Clinical Trials as Topic; Cough; Cyclopentanes; Diethylamines; Female; Humans; Male; Middle Aged; Placebos; Time Factors; Tuberculosis

1974

Other Studies

33 other study(ies) available for diphenhydramine hydrochloride and cyclopentane

ArticleYear
Studies on the potency of various antitussive agents.
    Agents and actions, 1977, Volume: 7, Issue:3

    Topics: Animals; Antitussive Agents; Cats; Clonazepam; Codeine; Cough; Cyclopentanes; Dextromethorphan; Diazepam; Ethylamines; Injections, Intravenous

1977
Non-opioid antitussives inhibit endogenous glutamate release from rabbit hippocampal slices.
    Brain research, 1991, Nov-15, Volume: 564, Issue:2

    Topics: Animals; Antitussive Agents; Aspartic Acid; Cyclopentanes; Depression, Chemical; Dextromethorphan; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Hippocampus; In Vitro Techniques; Male; Potassium; Rabbits

1991
Effects of non-opioid antitussives on epileptiform activity and NMDA responses in hippocampal and olfactory cortex slices.
    Brain research, 1990, Oct-08, Volume: 529, Issue:1-2

    Topics: Animals; Antitussive Agents; Cyclopentanes; Dextromethorphan; Electric Stimulation; Epilepsy; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; N-Methylaspartate; Olfactory Bulb

1990
Prevention of soman neurotoxicity by non-opioid antitussives.
    Neurotoxicology, 1990,Fall, Volume: 11, Issue:3

    Topics: Animals; Anticonvulsants; Antitussive Agents; Cyclopentanes; Dextromethorphan; Guinea Pigs; Male; Necrosis; Nervous System Diseases; Neurons; Soman

1990
Caramiphen: a non-opioid antitussive with potent anticonvulsant properties in rats.
    European journal of pharmacology, 1988, Oct-11, Volume: 155, Issue:1-2

    Topics: Animals; Anticonvulsants; Antitussive Agents; Atropine; Behavior, Animal; Cyclopentanes; Electroshock; Injections, Subcutaneous; Male; Phenytoin; Physostigmine; Rats; Rats, Inbred Strains; Time Factors

1988
[Pentoxyverine poisoning via maternal milk in a fully breast-fed newborn infant].
    Deutsche medizinische Wochenschrift (1946), 1988, Jun-03, Volume: 113, Issue:22

    Topics: Adult; Antitussive Agents; Breast Feeding; Cyclopentanes; Female; Humans; Infant, Newborn; Male; Milk, Human

1988
Colorimetric determination of pentoxiverine citrate in some pharmaceutical preparations.
    Die Pharmazie, 1987, Volume: 42, Issue:7

    Topics: Antitussive Agents; Colorimetry; Cyclopentanes

1987
Dextromethorphan and carbetapentane: centrally acting non-opioid antitussive agents with novel anticonvulsant properties.
    Brain research, 1986, Sep-24, Volume: 383, Issue:1-2

    Topics: Animals; Anticonvulsants; Antitussive Agents; Cyclopentanes; Dextromethorphan; Drug Synergism; Electroshock; Levorphanol; Male; Phenytoin; Rats; Rats, Inbred Strains; Seizures

1986
[Construction and analytical applications of an all-solid-state carbetapentane ion-selective electrode].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1986, Volume: 21, Issue:4

    Topics: Animals; Antitussive Agents; Cyclopentanes; Electrodes; Humans; Potentiometry

1986
Evidence for a central site of action for the antitussive effects of caramiphen.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1

    Topics: Animals; Antitussive Agents; Brain Stem; Cats; Cough; Cyclopentanes; Decerebrate State; Dextromethorphan; Female

1985
[Study on lung function after administration of the antitussive pentoxyverine].
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:2

    Topics: Airway Resistance; Antitussive Agents; Bronchodilator Agents; Carboxylic Acids; Cyclopentanes; Ethylamines; Humans; Metaproterenol; Plethysmography, Whole Body; Pulmonary Ventilation; Respiration

1972
[Effects of intravenous injection of carbetapentane citrate on the cardiovascular system and its clinical experiences].
    Masui. The Japanese journal of anesthesiology, 1970, Volume: 19, Issue:11

    Topics: Adolescent; Adult; Aged; Animals; Antitussive Agents; Blood Pressure; Cardiac Output; Cardiovascular System; Cyclopentanes; Dogs; Female; Heart Rate; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Regional Blood Flow; Renal Artery

1970
Use of nitrogen-specific detector for GLC determination of caramiphen in whole blood.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:11

    Topics: Antitussive Agents; Chromatography, Gas; Cyclopentanes; Humans

1980
Non-opioid antitussives potentiate some behavioural and EEG effects of N-methyl-D-aspartate channel blockers.
    Life sciences, 1993, Volume: 52, Issue:19

    Topics: Animals; Antitussive Agents; Behavior, Animal; Cyclopentanes; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Ion Channels; Male; Mice; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1993
Novel 1-phenylcycloalkanecarboxylic acid derivatives are potent and selective sigma 1 ligands.
    Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15

    Topics: Animals; Anticonvulsants; Antitussive Agents; Binding Sites; Cyclopentanes; In Vitro Techniques; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Receptors, sigma; Structure-Activity Relationship

1994
Effects of non-opioid antitussives on hypoxia-induced electrical changes in rat hippocampal slices: a comparative study with anticonvulsant drugs.
    General pharmacology, 1993, Volume: 24, Issue:4

    Topics: Animals; Anticonvulsants; Antitussive Agents; Cyclopentanes; Dizocilpine Maleate; Electrophysiology; Epilepsy; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Membrane Potentials; Phenytoin; Rats; Rats, Wistar

1993
Propiverine-induced Parkinsonism: a case report and a pharmacokinetic/pharmacodynamic study in mice.
    Pharmaceutical research, 2000, Volume: 17, Issue:5

    Topics: Animals; Antitussive Agents; Benzilates; Catalepsy; Cholinergic Antagonists; Cyclopentanes; Male; Mandelic Acids; Mice; Neostriatum; Parkinson Disease, Secondary; Pharmaceutical Solutions; Propafenone; Receptors, Cholinergic; Receptors, Dopamine D1; Receptors, Dopamine D2

2000
A non-potentiometric sensing method for the determination of pentoxyverine with PQC sensors based on ion-pair complexes.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2001, Volume: 17, Issue:12

    Topics: Antitussive Agents; Chemistry Techniques, Analytical; Cyclopentanes; Quartz

2001
An evaluation of caramiphen ethane disulfonate as an antitussive agent.
    The Laryngoscope, 1953, Volume: 63, Issue:10

    Topics: Antitussive Agents; Cough; Cyclopentanes; Ethane

1953
A new non-narcotic antitussive agent.
    Medical times, 1955, Volume: 83, Issue:9

    Topics: Antitussive Agents; Cough; Cyclopentanes; Narcotics

1955
[Action of phenanthrene derivatives and of synthetic antitussive substances on bronchospasm induced by histamine and acetylcholine].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1955, Volume: 149, Issue:9-10

    Topics: Acetylcholine; Antitussive Agents; Bronchi; Bronchial Diseases; Bronchial Spasm; Cyclopentanes; Disease; Histamine; Histamine Agents; Humans; Naphthalenes; Opium; Phenanthrenes; Spasm

1955
Quantitative comparison of cough-suppressing effects of romilar and other antitussives.
    The Journal of laboratory and clinical medicine, 1956, Volume: 48, Issue:6

    Topics: Antitussive Agents; Codeine; Cough; Cyclopentanes; Dextromethorphan; Morphine Derivatives; Opioid-Related Disorders

1956
The evaluation of a cough suppressant: an exercise in clinical pharmacology.
    Canadian Medical Association journal, 1959, May-01, Volume: 80, Issue:9

    Topics: Antitussive Agents; Cough; Cyclopentanes; Exercise; Humans; Pharmacology, Clinical

1959
[Use in surgery of a new synthetic antitussive drug; clinical study].
    Gazzetta medica italiana, 1959, Volume: 118, Issue:1

    Topics: Antitussive Agents; Biomedical Research; Cough; Cyclopentanes; Humans

1959
Study of a new sustained-release antitussive preparation (carbetapentane).
    The Medical annals of the District of Columbia, 1961, Volume: 30

    Topics: Antitussive Agents; Cough; Cyclopentanes; Delayed-Action Preparations

1961
THE SYNTHESIS AND ANTITUSSIVE PROPERTIES OF SOME CYCLOPENTANE DERIVATIVES.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Antitussive Agents; Cats; Chemistry, Pharmaceutical; Codeine; Cyclopentanes; Pharmacology; Research

1963
Cold, cough, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use; final rule for over-the-counter antitussive drug products; technical amendment. Final rule, technical amendment.
    Federal register, 2007, Nov-30, Volume: 72, Issue:230

    Topics: Antitussive Agents; Consumer Product Safety; Cyclopentanes; Drug Labeling; Humans; Nonprescription Drugs; United States; United States Food and Drug Administration

2007
Intrathecal administration of sigma-1 receptor agonists facilitates nociception: involvement of a protein kinase C-dependent pathway.
    Journal of neuroscience research, 2008, Volume: 86, Issue:16

    Topics: Animals; Antitussive Agents; Calcium Signaling; Cyclopentanes; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Inflammation Mediators; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morpholines; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells; Protein Kinase C; Proto-Oncogene Proteins c-fos; Receptors, sigma; Sigma-1 Receptor; Signal Transduction; Spinal Cord

2008
Effects of common antitussive drugs on the hERG potassium channel current.
    Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:6

    Topics: Amino Alcohols; Animals; Antitussive Agents; CHO Cells; Codeine; Cricetinae; Cricetulus; Cyclopentanes; Dextromethorphan; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Membrane Potentials; Potassium; Potassium Channel Blockers; Theobromine; Time Factors; Torsades de Pointes; Transfection

2008
Antidepressant-like effect of centrally acting non-narcotic antitussive caramiphen in a forced swimming test.
    Neuroscience letters, 2010, Sep-13, Volume: 481, Issue:3

    Topics: Animals; Antidepressive Agents; Antitussive Agents; Behavior, Animal; Cyclopentanes; Male; Motor Activity; Rats; Rats, Wistar; Stress, Psychological; Swimming

2010
Characterization of pentoxyverine metabolites in urine using GC/MS after intoxication with Silomat cough drops.
    Forensic science international, 2012, Feb-10, Volume: 215, Issue:1-3

    Topics: Amino Alcohols; Antitussive Agents; Child, Preschool; Cyclopentanes; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male

2012
Extraction-free spectrophotometric assay of the antitussive drug pentoxyverine citrate using sulfonephthalein dyes.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2019, Nov-05, Volume: 222

    Topics: Antitussive Agents; Coloring Agents; Cyclopentanes; Humans; Limit of Detection; Phenolsulfonphthalein; Solvents; Spectrophotometry; Tablets

2019
Carbetapentane citrate.
    Profiles of drug substances, excipients, and related methodology, 2020, Volume: 45

    Topics: Antitussive Agents; Cough; Cyclopentanes; Humans

2020