Page last updated: 2024-08-20

diphenhydramine hydrochloride and chlorpheniramine

diphenhydramine hydrochloride has been researched along with chlorpheniramine in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199012 (29.27)18.7374
1990's5 (12.20)18.2507
2000's16 (39.02)29.6817
2010's7 (17.07)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Das Gupta, V; de Lara, AJ1
Ishigooka, J; Murasaki, M; Yoshida, Y1
Masukawa, Y; Misawa, M; Suzuki, T1
Koike, Y; Misawa, M; Suzuki, T; Yanaura, S; Yoshida, E; Yoshii, T1
Bassow, L; Orson, J1
Moscucci, M; Weintraub, M1
Mahato, SB; Maitra, SK; Sahu, NP1
Doyle, TD; Levine, J1
Ponder, C1
Mario, E; Meehan, LG1
Lange, WE; Pruyn, FJ; Theodore, JM1
Zhang, JY1
Bolser, DC; Chapman, RW; DeGennaro, FC; Hey, JA; O'Reilly, S1
Sakai, M; Shimada, K; Yamato, S1
Kamei, J; Morita, K; Ohsawa, M; Onodera, K1
Fukui, K; Kita, H; Kitabayashi, Y; Nakamura, K; Narumoto, J; Tani, N; Tsuchida, H; Ueda, H1
Anderson, IB; Banerji, S1
Date, K; Doi, T; Miyatake, R; Naitoh, T; Suwaki, H1
Baker, SD; Borys, DJ1
Tang, C; Wu, X; Yin, C1
SNYDER, AJ1
EPSTEIN, J; KAPLAN, H; SHERWOOD, H1
Chan, R; Lee, AC; So, KT1
Chan, CH; Ng, DK; Tong, TF1
Miller, SC1
Dewan, V; Petty, F; Sharma, A1
Schwartz, RH1
Chmara, ES; Collins, GL; Mundy, LA; Wingert, WE1
Chen, H; Chen, X; Liu, L; Liu, X1
Manabe, H; Murao, S; Sekikawa, T; Yamashita, T1
Chen, X; Liu, X; Zhang, J1
Karamanakos, PN1
Adhoum, N; Jebali, S; Loueslati, MH; Louhaichi, MR; Monser, L1
Li, X; Liang, S; Liu, B; Lü, H; Qiu, Z; Wang, L; Wang, Y; Wei, W; Yu, L1
Bodmer, M; Chuang, R; Monte, AA1
Ameno, K; Jamal, M; Kinoshita, H; Kumihashi, M; Okuzono, R; Tanaka, N1
Padma, L1
Mallefet, P; Zhang, Y1
Boltia, SA; Elzanfaly, ES; Soudi, AT; Zaazaa, HE1
Banner, W; Bond, GR; Dart, RC; Delva-Clark, H; Green, JL; Halmo, LS; Kauffman, RE; Palmer, RB; Paul, IM; Rapp-Olsson, M; Reynolds, KM; Wang, GS1

Reviews

3 review(s) available for diphenhydramine hydrochloride and chlorpheniramine

ArticleYear
Adolescent abuse of dextromethorphan.
    Clinical pediatrics, 2005, Volume: 44, Issue:7

    Topics: Acetaminophen; Adolescent; Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Combinations; Humans; Nonprescription Drugs; Phenylpropanolamine; Substance-Related Disorders

2005
Dextromethorphan, chlorphenamine and serotonin toxicity: case report and systematic literature review.
    British journal of clinical pharmacology, 2010, Volume: 70, Issue:6

    Topics: Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Overdose; Humans; Male; Serotonin Agents; Suicide, Attempted; Young Adult

2010
Current drugs for the treatment of dry cough.
    The Journal of the Association of Physicians of India, 2013, Volume: 61, Issue:5 Suppl

    Topics: Antitussive Agents; Bronchodilator Agents; Chlorpheniramine; Codeine; Cough; Drug Therapy, Combination; Expectorants; Histamine Antagonists; Humans

2013

Trials

3 trial(s) available for diphenhydramine hydrochloride and chlorpheniramine

ArticleYear
Taste preference for cough syrups: a comparative study of three codeine-containing medications.
    Clinical therapeutics, 1986, Volume: 8, Issue:3

    Topics: Antitussive Agents; Chlorpheniramine; Codeine; Drug Combinations; Glycerol; Humans; Promethazine; Taste

1986
Efficacy and safety of modified sequential three-step empirical therapy for chronic cough.
    Respirology (Carlton, Vic.), 2010, Volume: 15, Issue:5

    Topics: Adult; Aminophylline; Antitussive Agents; Budesonide; Cetirizine; Chlorpheniramine; Chronic Disease; Cough; Domperidone; Drug Therapy, Combination; Empirical Research; Humans; Methamphetamine; Middle Aged; Noscapine; Omeprazole; Prednisone; Prospective Studies; Quality of Life; Sleep Stages; Treatment Outcome

2010
Time-to-onset of cold and flu symptom relief: A randomized, double-blind, placebo-controlled pilot study for a multi-symptom combination product.
    International journal of clinical pharmacology and therapeutics, 2018, Volume: 56, Issue:12

    Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Antitussive Agents; China; Chlorpheniramine; Common Cold; Dextromethorphan; Double-Blind Method; Drug Combinations; Female; Histamine H1 Antagonists; Humans; Influenza, Human; Male; Middle Aged; Nasal Decongestants; Patient Satisfaction; Pilot Projects; Pseudoephedrine; Remission Induction; Tablets; Time Factors; Treatment Outcome

2018

Other Studies

35 other study(ies) available for diphenhydramine hydrochloride and chlorpheniramine

ArticleYear
Colorimetric determinations of chlorpheniramine maleate, ephedrine hydrochloride, and guaiacolsulfonate potassium in a cough syrup.
    Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:12

    Topics: Antitussive Agents; Chlorpheniramine; Colorimetry; Ephedrine; Guaiacol; Methods

1975
Abuse of "BRON": a Japanese OTC cough suppressant solution containing methylephedrine, codeine, caffeine and chlorpheniramine.
    Progress in neuro-psychopharmacology & biological psychiatry, 1991, Volume: 15, Issue:4

    Topics: Adult; Antitussive Agents; Caffeine; Chlorpheniramine; Codeine; Drug Combinations; Ephedrine; Female; Hallucinations; Humans; Japan; Male; Nonprescription Drugs; Paranoid Disorders; Psychoses, Substance-Induced; Substance-Related Disorders

1991
Drug interactions in the reinforcing effects of over-the-counter cough syrups.
    Psychopharmacology, 1990, Volume: 102, Issue:4

    Topics: Animals; Antitussive Agents; Benzazepines; Chlorpheniramine; Codeine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Morphine; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Substance-Related Disorders

1990
[The effects of noscapine and chlorpheniramine on physical dependence and antitussive activity of dihydrocodeine].
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1988, Volume: 8, Issue:2

    Topics: Animals; Antitussive Agents; Body Weight; Chlorpheniramine; Codeine; Drug Interactions; Guinea Pigs; Male; Noscapine; Rats; Rats, Inbred Strains; Substance-Related Disorders

1988
Over-the-counter cough formulas.
    Clinical pediatrics, 1987, Volume: 26, Issue:6

    Topics: Antitussive Agents; Child; Child, Preschool; Chlorpheniramine; Female; Humans; Male; Nonprescription Drugs; Phenylpropanolamine

1987
Simultaneous determination of chlorpheniramine and diphenhydramine in cough syrups by reversed-phase ion-pair high-performance liquid chromatography.
    Journal of chromatography, 1986, Jan-31, Volume: 351, Issue:3

    Topics: Antitussive Agents; Chlorpheniramine; Chromatography, High Pressure Liquid; Diphenhydramine

1986
Determination of phenylephrine in combinations with other drugs.
    Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:5

    Topics: Acetaminophen; Antitussive Agents; Aspirin; Chlorpheniramine; Chromatography; Dosage Forms; Expectorants; Guaifenesin; Histamine H1 Antagonists; Magnesium; Phenolphthaleins; Phenylephrine; Phenylpropanolamine; Solutions; Sympathomimetics; Tablets; Ultraviolet Rays

1967
Determination of phenylephrine hydrochloride in combination with other drugs.
    Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:3

    Topics: Aerosols; Antitussive Agents; Aspirin; Chemistry, Pharmaceutical; Chlorobutanol; Chlorpheniramine; Chromatography; Codeine; Histamine H1 Antagonists; Magnesium; Parasympatholytics; Pharmaceutic Aids; Pheniramine; Phenylephrine; Phenylpropanolamine; Solutions; Spectrophotometry; Sulfites; Tablets

1968
Simultaneous determination of nonderivated phenylpropanolamine, glyceryl guaiacolate, chlorpheniramine, and dextromethorphan by gas chromatography.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:4

    Topics: Alkaloids; Amino Alcohols; Antitussive Agents; Chlorpheniramine; Chromatography, Gas; Guaifenesin; Hydroquinones; Mathematics; Methods; Morphinans; Morpholines; Phenethylamines; Phenylpropanolamine; Sympathomimetics

1970
In vivo determination of certain aralkylamines.
    Journal of pharmaceutical sciences, 1968, Volume: 57, Issue:1

    Topics: Amino Alcohols; Antitussive Agents; Chlorpheniramine; Chromatography, Thin Layer; Fluoresceins; Fluorometry; Microchemistry; Phenethylamines; Phenylephrine; Phenylpropanolamine; Rose Bengal; Sympathomimetics

1968
[Clinical and experimental observations on chronic bronchitis treated with pukeling].
    Zhonghua jie he he hu xi xi ji bing za zhi = Chinese journal of tuberculosis and respiratory diseases, 1983, Volume: 6, Issue:3

    Topics: Animals; Antitussive Agents; Bronchitis; Cats; China; Chlorpheniramine; Drug Combinations; Drugs, Chinese Herbal; Guinea Pigs; Humans; Mice; Plant Extracts; Propantheline

1983
Pharmacological studies of allergic cough in the guinea pig.
    European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3

    Topics: Administration, Oral; Aerosols; Albuterol; Analysis of Variance; Animals; Antitussive Agents; Capsaicin; Chlorpheniramine; Cimetidine; Codeine; Cough; Drug Hypersensitivity; Guinea Pigs; Hexamethonium; Histamine Antagonists; Indomethacin; Injections, Subcutaneous; Ipratropium; Loratadine; Male; Ovalbumin; Piperidines; Receptors, Histamine H1; Receptors, Histamine H2

1995
[Quantitative analysis of chlorpheniramine maleate in cough and cold drugs by ion-pair high-performance liquid chromatography for the simultaneous determination of chlorpheniramine and maleate].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1996, Volume: 116, Issue:4

    Topics: Antitussive Agents; Chlorpheniramine; Chromatography, High Pressure Liquid; Histamine H1 Antagonists; Maleates

1996
Effects of epinastine on the antitussive and rewarding effects of dihydrocodeine in mice.
    Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:10

    Topics: Animals; Antitussive Agents; Chlorpheniramine; Codeine; Conditioning, Operant; Cough; Dibenzazepines; Drug Synergism; Histamine H1 Antagonists; Imidazoles; Male; Mice; Mice, Inbred ICR; Reward

1999
[A case study of BRON (cough suppressant) tablet dependence--its social psychiatric and biological aspects].
    Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, 2000, Volume: 35, Issue:5

    Topics: Adolescent; Antitussive Agents; Caffeine; Cerebrovascular Circulation; Chlorpheniramine; Codeine; Community Psychiatry; Drug Combinations; Ephedrine; Frontal Lobe; Humans; Male; Motivation; Nonprescription Drugs; Psychoses, Substance-Induced; Substance-Related Disorders; Syndrome

2000
Abuse of Coricidin HBP cough & cold tablets: episodes recorded by a poison center.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2001, Oct-01, Volume: 58, Issue:19

    Topics: Adolescent; Adult; Antitussive Agents; California; Chlorpheniramine; Common Cold; Cough; Dextromethorphan; Drug Utilization Review; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Nonprescription Drugs; Poison Control Centers; Self Medication; Substance-Related Disorders

2001
[Clinical study of BRON-L syrup (cough suppressant) abuse].
    Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence, 2002, Volume: 37, Issue:1

    Topics: Adult; Antitussive Agents; Caffeine; Chlorpheniramine; Drug Combinations; Female; Humans; Male; Nonprescription Drugs; Substance-Related Disorders

2002
A possible trend suggesting increased abuse from Coricidin exposures reported to the Texas Poison Network: comparing 1998 to 1999.
    Veterinary and human toxicology, 2002, Volume: 44, Issue:3

    Topics: Acetaminophen; Adolescent; Adolescent Behavior; Age Factors; Antitussive Agents; Child; Chlorpheniramine; Databases, Factual; Dextromethorphan; Drug Combinations; Drug Overdose; Female; Humans; Incidence; Male; Medical Records; Nonprescription Drugs; Phenylpropanolamine; Population Surveillance; Retrospective Studies; Texas

2002
HPLC determination of aminophylline, methoxyphenamine hydrochloride, noscapine and chlorphenamine maleate in compound dosage forms with an aqueous-organic mobile phase.
    Journal of pharmaceutical and biomedical analysis, 2003, Sep-15, Volume: 33, Issue:1

    Topics: Adrenergic beta-Agonists; Aminophylline; Antitussive Agents; Bronchodilator Agents; Capsules; Chlorpheniramine; Chromatography, High Pressure Liquid; Drug Combinations; Indicators and Reagents; Methamphetamine; Noscapine; Reference Standards; Reproducibility of Results; Solutions; Spectrophotometry, Ultraviolet

2003
HOW RELIABLY CAN INDUSTRIAL DISPENSARIES RATE THE SAME DRUG GIVEN IN DISGUISED FORMS.
    Industrial medicine & surgery, 1964, Volume: 33

    Topics: Antitussive Agents; Biomedical Research; Chlorpheniramine; Common Cold; Drug Therapy; Humans; Industry; Occupational Health Nursing; Sympathomimetics

1964
CLINICAL IMPRESSION AND SUBSEQUENT DOUBLE BLIND STUDY OF AN ANTITUSSIVE PREPARATION.
    Annals of allergy, 1965, Volume: 23

    Topics: Antitussive Agents; Biomedical Research; Chlorpheniramine; Double-Blind Method; Drug Therapy; Ephedrine; Humans; Phenylephrine; Respiratory Tract Infections

1965
A case of probable codeine poisoning in a young infant after the use of a proprietary cough and cold medicine.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2004, Volume: 10, Issue:4

    Topics: Antitussive Agents; Chlorpheniramine; Codeine; Humans; Infant; Male; Nonprescription Drugs; Stereoisomerism

2004
Prescription of codeine in young infants.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2004, Volume: 10, Issue:6

    Topics: Antitussive Agents; Chlorpheniramine; Codeine; Cyanosis; Female; Histamine H1 Antagonists; Humans; Infant, Newborn; Oxygen Inhalation Therapy; Promethazine; Sleep Apnea Syndromes; Treatment Outcome

2004
Coricidin HBP cough and cold addiction.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2005, Volume: 44, Issue:6

    Topics: Acetaminophen; Adolescent; Animals; Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Combinations; Humans; Male; Nonprescription Drugs; Phenylpropanolamine; Substance Abuse Detection; Substance Withdrawal Syndrome; Substance-Related Disorders

2005
Acute psychosis with Coricidin cold medicine.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:9

    Topics: Acute Disease; Antitussive Agents; Chlorpheniramine; Dextromethorphan; Drug Combinations; Histamine H1 Antagonists; Humans; Male; Middle Aged; Nonprescription Drugs; Psychoses, Substance-Induced

2005
Possible role of pseudoephedrine and other over-the-counter cold medications in the deaths of very young children.
    Journal of forensic sciences, 2007, Volume: 52, Issue:2

    Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antitussive Agents; Brompheniramine; Bronchodilator Agents; Cause of Death; Central Nervous System Depressants; Child; Child, Preschool; Chlorpheniramine; Common Cold; Databases as Topic; Dextromethorphan; Doxylamine; Ephedrine; Ethanol; Female; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Histamine H1 Antagonists; Humans; Infant; Male; Nonprescription Drugs; Philadelphia; Pyridines

2007
Separation and determination of four active components in medicinal preparations by flow injection-capillary electrophoresis.
    Journal of pharmaceutical and biomedical analysis, 2007, Apr-11, Volume: 43, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Antitussive Agents; Bronchodilator Agents; Buffers; Chlorpheniramine; Common Cold; Dextromethorphan; Electrophoresis, Capillary; Ephedrine; Flow Injection Analysis; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Maleates; Reproducibility of Results; Time Factors

2007
Intoxication with over-the-counter antitussive medication containing dihydrocodeine and chlorpheniramine causes generalized convulsion and mixed acidosis.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:11

    Topics: Acidosis; Adult; Antitussive Agents; Chlorpheniramine; Codeine; Ephedrine; Humans; Japan; Male; Nonprescription Drugs; Seizures; Substance-Related Disorders

2008
Online concentration by head-column field-amplified with large-volume sample stacking using flow injection-capillary electrophoresis for the analysis of four active components in cold medicines.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2008, Volume: 24, Issue:8

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Allergic Agents; Antitussive Agents; Chlorpheniramine; Common Cold; Dextromethorphan; Electrophoresis, Capillary; Flow Injection Analysis; Nasal Decongestants; Pharmaceutical Preparations; Pseudoephedrine; Reproducibility of Results; Sensitivity and Specificity; Time Factors

2008
Intoxication with over-the-counter antitussive medication containing dihydrocodeine and chlorpheniramine causes generalized convulsion and mixed acidosis.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:20

    Topics: Acidosis; Adult; Animals; Antitussive Agents; Chlorpheniramine; Codeine; Dose-Response Relationship, Drug; Drug Overdose; Humans; Male; Mice; Models, Animal; Nonprescription Drugs; Rats; Seizures; Serotonin 5-HT1 Receptor Agonists

2008
Simultaneous determination of pseudoephdrine, pheniramine, guaifenisin, pyrilamine, chlorpheniramine and dextromethorphan in cough and cold medicines by high performance liquid chromatography.
    Talanta, 2009, May-15, Volume: 78, Issue:3

    Topics: Antitussive Agents; Calibration; Chlorpheniramine; Chromatography, High Pressure Liquid; Dextromethorphan; Expectorants; Guaifenesin; Pharmaceutical Preparations; Pheniramine; Pseudoephedrine; Pyrilamine; Reproducibility of Results

2009
A fatal case due to cough syrup abuse.
    Soudni lekarstvi, 2012, Volume: 57, Issue:4

    Topics: Adult; Antitussive Agents; Chlorpheniramine; Codeine; Female; Humans

2012
Hydrocodone/chlorpheniramine (Vituz).
    The Medical letter on drugs and therapeutics, 2013, Nov-25, Volume: 55, Issue:1430

    Topics: Adult; Anti-Allergic Agents; Antitussive Agents; Chlorpheniramine; Cough; Drug Combinations; Drug Interactions; Humans; Hydrocodone

2013
Simultaneous Quantification of Chlorpheniramine, Phenylephrine, Guaifenesin in Presence of Preservatives with Detection of Related Substance Guaiacol in their Cough Syrup by RP-HPLC and TLC-Densitometric Methods.
    Journal of chromatographic science, 2019, Jul-01, Volume: 57, Issue:6

    Topics: Antitussive Agents; Chlorpheniramine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Guaiacol; Guaifenesin; Linear Models; Phenylephrine; Preservatives, Pharmaceutical; Reproducibility of Results; Sensitivity and Specificity

2019
Pediatric Fatalities Associated With Over-the-Counter Cough and Cold Medications.
    Pediatrics, 2021, Volume: 148, Issue:5

    Topics: Antitussive Agents; Brompheniramine; Child; Child, Preschool; Chlorpheniramine; Dextromethorphan; Diphenhydramine; Doxylamine; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Female; Guaifenesin; Homicide; Humans; Infant; Male; Nonprescription Drugs; Phenylephrine; Pseudoephedrine

2021