diphenhydramine and zolpidem

diphenhydramine has been researched along with zolpidem in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (50.00)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Choi, Y; Raymer, BK1
Miyamoto, M; Terao, A1
Horner, RL; Liu, H; Liu, X; Park, E; Younes, M1
Luks, AM1
Aritake, S; Enomoto, M; Hida, A; Katayose, Y; Kitamura, S; Mishima, K; Takahashi, K1
Krocker, K; Sautter, J; Tattoli, L; Tsokos, M1
Ahmad, M; Chen, LB; Dahl, T; Roth, T; Zammit, G1

Reviews

4 review(s) available for diphenhydramine and zolpidem

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Sleep modulating agents.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Animals; Humans; Sleep; Sleep Aids, Pharmaceutical; Sleep Wake Disorders; Wakefulness-Promoting Agents

2019
[Recent and potential drugs for treatment of insomnia].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2007, Volume: 129, Issue:1

    Topics: Animals; Azabicyclo Compounds; Benzodiazepines; Diphenhydramine; Drug Design; Fluorobenzenes; GABA-A Receptor Agonists; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Indenes; Orexin Receptors; Phenols; Piperazines; Pyridines; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Serotonin 5-HT2 Receptor Antagonists; Sleep Initiation and Maintenance Disorders; Thiophenes; Zolpidem

2007
Which medications are safe and effective for improving sleep at high altitude?
    High altitude medicine & biology, 2008,Fall, Volume: 9, Issue:3

    Topics: Acetamides; Acetazolamide; Altitude Sickness; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Diphenhydramine; Eszopiclone; GABA Agonists; Humans; Hypnotics and Sedatives; Mountaineering; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Sleep Stages; Temazepam; Wakefulness; Zolpidem

2008

Trials

2 trial(s) available for diphenhydramine and zolpidem

ArticleYear
Carryover effect on next-day sleepiness and psychomotor performance of nighttime administered antihistaminic drugs: a randomized controlled trial.
    Human psychopharmacology, 2012, Volume: 27, Issue:4

    Topics: Blood-Brain Barrier; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Ketotifen; Male; Polysomnography; Psychomotor Performance; Pyridines; Sleep; Sleep Stages; Time Factors; Tissue Distribution; Young Adult; Zolpidem

2012
Efficacy of SM-1 in a transient insomnia model.
    Human psychopharmacology, 2019, Volume: 34, Issue:6

    Topics: Adult; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Drug Combinations; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Polysomnography; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Zolpidem

2019

Other Studies

8 other study(ies) available for diphenhydramine and zolpidem

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Systemic vs. central administration of common hypnotics reveals opposing effects on genioglossus muscle activity in rats.
    Sleep, 2008, Volume: 31, Issue:3

    Topics: Animals; Arousal; Brain; Carbon Dioxide; Diaphragm; Diphenhydramine; Dose-Response Relationship, Drug; Electromyography; Hypnotics and Sedatives; Hypoglossal Nerve; Injections, Intraperitoneal; Lorazepam; Male; Microdialysis; Motor Neurons; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Respiratory Muscles; Sleep; Tongue; Vagotomy; Vagus Nerve; Zolpidem

2008
Multidrug-related leukocytoclastic vasculitis raising suspicion of sexual homicide-things are not always what they seem.
    International journal of legal medicine, 2016, Volume: 130, Issue:1

    Topics: Adult; Analgesics, Opioid; Anti-Anxiety Agents; Antidepressive Agents; Azabicyclo Compounds; Benzhydryl Compounds; Calcium Channel Blockers; Desvenlafaxine Succinate; Diphenhydramine; Female; Forensic Pathology; Hemorrhage; Humans; Hypnotics and Sedatives; Lamotrigine; Modafinil; Piperazines; Pregabalin; Pyridines; Subcutaneous Tissue; Tramadol; Triazines; Vasculitis, Leukocytoclastic, Cutaneous; Wakefulness-Promoting Agents; Zolpidem

2016