diphenhydramine and pyrilamine

diphenhydramine has been researched along with pyrilamine in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	30 (43.48)	18.7374
1990's	15 (21.74)	18.2507
2000's	19 (27.54)	29.6817
2010's	4 (5.80)	24.3611
2020's	1 (1.45)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Strassburg, CP; Tukey, RH	1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Hashimoto, N; Nezu Ji, J; Nikaido, H; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A	1
Bakker, RA; Booth, RG; Choksi, NY; Leurs, R; Moniri, NH; Nix, WB; Timmerman, H	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Caron, G; Ermondi, G	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Ahman, M; Holmén, AG; Wan, H	1
Elz, S; Strasser, A; Wagner, E; Wittmann, HJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Ham, NS	1
Duchene-Marullaz, P; Dureng, G; Labrid, C; Moleyre, J	1
Kaliner, M	2
Papadimituiou, JM; Sforcina, D	1
Anttila, P; Lücke, C; Westermann, E	1
Akiyama, Y; Kamei, C; Mukai, T; Tasaka, K	1
Dannals, RF; Natarajan, TK; Ravert, HT; Sánchez-Roa, PM; Vazquez, S; Villemagne, VL; Wagner, HN; Wilson, AA; Wong, DF; Yanai, K	1
Akamine, M; Kitazawa, T; Kondo, H; Ohta, T; Shimizu, T; Temma, K	1
Foxwell, MH; Johnson, DN; Kilpatrick, BF; Leonard, CA; Nolan, JC; Proakis, AG; Stephens, DJ; Yanni, JM	1
Hanig, JP; Hui, FW; Sun, CL	1
Katona, PG; Rigel, DF	1
Fleisch, JH; Haisch, KD; Rinkema, LE; Whitesitt, CA	1
Cordeiro, RS; Corrêa, FM; Henriques, MG; Martins, MA; Silva, PM	1
Akahori, H; Kamei, C; Kitazumi, K; Tasaka, K	1
Fromm, D; Furukawa, T; Olender, EJ; Woods, DJ	1
Jantos, H; Monti, JM; Pellejero, T	1
Katayama, S; Tasaka, K	1
Bentley, GA; Story, ME	1
Awouters, F; Janssen, PA; Van den Broeck, WA; Wauquier, A	1
Kaminka, ME; Mashkovskiĭ, MD; Tupikina, SM	1
Olive, G; Onnen, I	1
Aghajanian, GK; Lakoski, JM	1
Langwiński, R; Malec, D	1
Kamei, C; Saito, T; Tagami, H; Tasaka, K	1
Kusunoki, M; Tanaka, C; Taniyama, K	1
Chader, GJ; Koh, SW	1
Chung, YH; Kamei, C; Miyake, H; Tasaka, K	1
Hunt, WA; Kaliner, M; Wescott, SL	1
Slotkin, TA; Subramanian, N; Whitmore, WL	1
Brown, PA; Vernikos, J	1
Edvinsson, L; Hedner, T; Sun, X	1
Danielson, ND; Holeman, JA	1
Iguchi, A; Kunoh, Y; Nonogaki, K; Sakamoto, N; Tamagawa, T; Zhu, LX	1
Ebert, EC; Leone, VM; Roberts, AI	1
Bélanger, A; Harris, WH; Yamashiro, S	1
Finlay-Jones, JJ; Hart, PH; Jones, CA; Jones, KL; Santucci, I; Spencer, LK; Watson, CJ	1
KAMEI, CH	1
Hanai, N; Kusano, A; Masaki, S; Miki, I; Ohmori, K; Ohta, S; Otoshi, M; Sato, S	1
Jafri, MS; Moore, KA; Taylor, GE; Weinreich, D	1
Cusack, B; Groshan, K; Richelson, E; Tyler, BM	1
Chen, Z; Kamei, C; Kaneko, Y; Saitou, K; Sugimoto, Y	1
Bartolini, A; Galeotti, N; Ghelardini, C	2
Chen, Z; Fujii, Y; Kamei, C; Sugimoto, Y; Suzuki, G	1
Fischer, HS; Humpel, C; Saria, A; Schatz, DS; Zernig, G	1
Carlson, BB; Salamone, JD; Trevitt, JT	1
Fujii, Y; Kamei, C; Nishiga, M; Sugimoto, Y; Taga, C	1
Chen, JQ; Chen, Z; Kamei, C	1
Merk, HF	1
Anisman, H; Hayley, S; Kelly, O	1
Fujii, Y; Harada, C; Hirai, T; Kamei, C; Tanaka, T	1
Adachi, Y; Fujii, Y; Kamei, C; Yamamoto, Y	1
Liu, B; Wang, C; Zhang, G; Zhang, H; Zhang, X	1
Wang, Z; Woolverton, WL	1
Kamei, C; Kato, A; Okada, A	1
Kamei, H; Kawami, M; Nagahiro, M; Takano, M; Yumoto, R	1
Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H	1

Reviews

2 review(s) available for diphenhydramine and pyrilamine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Standard treatment: the role of antihistamines. The journal of investigative dermatology. Symposium proceedings, 2001, Volume: 6, Issue:2 Topics: Cyclizine; Cytochrome P-450 Enzyme System; Diphenhydramine; Electrocardiography; Histamine H1 Antagonists; Humans; Promethazine; Pyrilamine; Urticaria	2001

Other Studies

67 other study(ies) available for diphenhydramine and pyrilamine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2. Molecular pharmacology, 2001, Volume: 59, Issue:2 Topics: Animals; Biological Transport; Carbon Radioisotopes; Carnitine; Carrier Proteins; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Tetraethylammonium; Tissue Distribution; Tritium	2001
A novel phenylaminotetralin radioligand reveals a subpopulation of histamine H(1) receptors. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:1 Topics: Animals; Binding, Competitive; Cell Membrane; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; DNA, Complementary; Guinea Pigs; Histamine; Histamine Agonists; Humans; Ileum; Inositol Phosphates; Ligands; NF-kappa B; Pyrilamine; Radiopharmaceuticals; Receptors, Histamine H1; Tetrahydronaphthalenes; Thermodynamics; Transfection; Type C Phospholipases	2002
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH(1)R, but low affinity to hH(4)R. Bioorganic & medicinal chemistry letters, 2011, Nov-01, Volume: 21, Issue:21 Topics: Histamine H1 Antagonists; Indoles; Models, Molecular; Piperazines; Pyrilamine; Receptors, Histamine H1	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Conformational populations for antihistamines and antihypertensives in solution. Journal of pharmaceutical sciences, 1976, Volume: 65, Issue:4 Topics: Antihypertensive Agents; Diphenhydramine; Guanethidine; Guanidines; Histamine H1 Antagonists; Methapyrilene; Molecular Conformation; Pyrilamine; Structure-Activity Relationship; Sympatholytics; Tripelennamine	1976
Dualist or pseudo-dualist interactions of mepyramine, diphenhydramine and eprozinol with histamine at H1-receptors. Japanese journal of pharmacology, 1977, Volume: 27, Issue:4 Topics: Animals; Binding, Competitive; Diphenhydramine; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Piperazines; Pyridines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Trachea	1977
Human lung tissue and anaphylaxis: the effects of histamine on the immunologic release of mediators. The American review of respiratory disease, 1978, Volume: 118, Issue:6 Topics: Antigens; Biological Assay; Cimetidine; Cyclic AMP; Cyclic GMP; Diphenhydramine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Humans; Lung; Methylhistamines; Metiamide; Pyrilamine; SRS-A	1978
Human lung tissue and anaphylaxis:cyclic nucleotide response and prostaglandin synthesis. Monographs in allergy, 1979, Volume: 14 Topics: Anaphylaxis; Cell Communication; Cyclic AMP; Cyclic GMP; Diphenhydramine; Histamine; Histamine Release; Humans; Lung; Prostaglandins; Prostaglandins F; Pyrilamine; Time Factors	1979
The effects of drugs on monocytic fusion in vivo. Experimental cell research, 1975, Mar-15, Volume: 91, Issue:2 Topics: Adenosine Triphosphatases; Animals; Calcium; Cell Fusion; Cell Membrane; Cortisone; Cyclic AMP; Diphenhydramine; Edetic Acid; Glucagon; Insulin; Isoproterenol; Lidocaine; Lysosomes; Male; Mice; Mice, Inbred C57BL; Monocytes; Ouabain; Pyrilamine; Tetracaine; Trifluoperazine; Verapamil	1975
Stimulation of adenylate cyclase of guinea pig gastric mucosa by histamine, sodium fluoride and 5'-guanylylimidodiphosphate and inhibition by histamine H1- and H2-receptor antagonists in vitro. Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 296, Issue:1 Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Diphenhydramine; Fluorides; Gastric Mucosa; Guanine Nucleotides; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Isoproterenol; Metiamide; Pentagastrin; Phenylephrine; Pyrilamine; Sodium Fluoride	1976
Histamine lipolysis I: changes in the free fatty acid levels of dog plasma after intravenous infusion of histamine. Methods and findings in experimental and clinical pharmacology, 1990, Volume: 12, Issue:5 Topics: Aminophylline; Animals; Chromatography, High Pressure Liquid; Diphenhydramine; Dogs; Epinephrine; Fatty Acids, Nonesterified; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Infusions, Intravenous; Lipolysis; Male; Methylhistamines; Pentobarbital; Pyrilamine; Starvation	1990
Imaging histamine H1 receptors in the living human brain with carbon-11-pyrilamine. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:2 Topics: Adult; Animals; Brain; Carbon Radioisotopes; Depression, Chemical; Diphenhydramine; Humans; Male; Papio; Pyrilamine; Receptors, Histamine H1; Tissue Distribution; Tomography, Emission-Computed	1991
Histamine directly acts on beta-adrenoceptors as well as H1-histaminergic receptors, and causes positive inotropic effects in isolated ventricular muscles of carp heart (Cyprinus carpio). Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1989, Volume: 92, Issue:1 Topics: Animals; Atropine; Carps; Cimetidine; Cyprinidae; Diphenhydramine; Electric Stimulation; Female; Histamine; Histamine Antagonists; In Vitro Techniques; Male; Myocardial Contraction; Propranolol; Pyrilamine; Receptors, Adrenergic, beta; Receptors, Histamine H1; Stereoisomerism	1989
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine. Agents and actions, 1989, Volume: 28, Issue:1-2 Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cats; Chlorpheniramine; Diphenhydramine; Electroencephalography; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Kinetics; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Oxazepines; Piperazines; Promethazine; Pyrilamine; Terfenadine; Yohimbine	1989
Effect of H1 blockers alone and in combination with morphine to produce antinociception in mice. Neuropharmacology, 1985, Volume: 24, Issue:1 Topics: Analgesics; Animals; Chlorpheniramine; Cyclizine; Diphenhydramine; Drug Synergism; Histamine H1 Antagonists; Male; Mice; Morphine; Phenothiazines; Pyrilamine	1985
Effects of antihistamines and local anesthetics on excess tachycardia in conscious dogs. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1 Topics: Anesthetics, Local; Animals; Atropine; Chlorpheniramine; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Lidocaine; Male; Procaine; Promethazine; Pyrilamine; Tachycardia	1986
Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist. Agents and actions, 1987, Volume: 20, Issue:1-2 Topics: Animals; Benzhydryl Compounds; Benzimidazoles; Bronchial Provocation Tests; Chlorpheniramine; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Lung; Male; Muscle, Smooth; Promethazine; Pyrilamine; Terfenadine; Triprolidine	1987
Plasmodium berghei-infected mice: lack of effect of meclizine and cimetidine on the development of pulmonary oedema. Annals of tropical medicine and parasitology, 1986, Volume: 80, Issue:5 Topics: Animals; Capillary Permeability; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Malaria; Male; Meclizine; Mice; Plasmodium berghei; Pulmonary Edema; Pyrilamine	1986
The effects of histamine and some related compounds on conditioned avoidance response in rats. Life sciences, 1985, Nov-25, Volume: 37, Issue:21 Topics: Acetylcholine; Animals; Avoidance Learning; Dimaprit; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Hypothalamus; Injections, Intraventricular; Kinetics; Male; Methylhistamines; Pyrilamine; Rats; Rats, Inbred Strains; Scopolamine; Thiazoles; Thiourea	1985
Histamine receptor effects on dissipation of an intracellular proton gradient of isolated gastric mucosal surface cells. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 185, Issue:4 Topics: Animals; Bicarbonates; Chlorides; Cimetidine; Dimaprit; Diphenhydramine; Gastric Acid; Gastric Mucosa; Histamine; Protons; Pyridines; Pyrilamine; Rabbits; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Sodium; Thiourea	1987
Effects of H1- and H2-histamine receptor agonists and antagonists on sleep and wakefulness in the rat. Journal of neural transmission, 1986, Volume: 66, Issue:1 Topics: Animals; Cimetidine; Diphenhydramine; Electroencephalography; Injections, Intraperitoneal; Injections, Intraventricular; Male; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Sleep, REM; Thiazoles; Wakefulness	1986
Effects of H1-receptor blocking drugs on the frog sartorius neuromuscular junction. British journal of pharmacology, 1985, Volume: 85, Issue:4 Topics: Action Potentials; Aminopyridines; Animals; Diphenhydramine; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Membrane Potentials; Neuromuscular Junction; Perfusion; Promethazine; Pyrilamine; Ranidae; Receptors, Histamine; Receptors, Histamine H1; Time Factors	1985
The effects of drugs and treatments upon adrenaline re-reversal in the rabbit. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:1 Topics: Animals; Blood Pressure; Bretylium Compounds; Cocaine; Diphenhydramine; Ear; Epinephrine; Female; Guanethidine; Hemorrhage; Hexamethonium Compounds; Hindlimb; Male; Muscle Contraction; Pentolinium Tartrate; Perfusion; Phenoxybenzamine; Portal Vein; Propantheline; Propranolol; Pyrilamine; Rabbits; Regional Blood Flow; Vagotomy; Vagus Nerve	1974
A comparison between astemizole and other antihistamines on sleep-wakefulness cycles in dogs. Neuropharmacology, 1981, Volume: 20, Issue:9 Topics: Animals; Astemizole; Benzimidazoles; Chlorpheniramine; Diphenhydramine; Dogs; Histamine H1 Antagonists; Ketotifen; Male; Periodicity; Pyrilamine; Sleep; Sleep Stages; Sleep, REM; Wakefulness	1981
[Effect of antihistaminic preparations on gastric secretion in rats]. Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 95, Issue:5 Topics: Animals; Benzhydryl Compounds; Carbolines; Cimetidine; Cyproheptadine; Diphenhydramine; Gastric Mucosa; Histamine H1 Antagonists; Male; Pyrilamine; Rats	1983
Desensitization of the isolated guinea pig ileum to antihistaminic agents. European journal of pharmacology, 1983, Jun-03, Volume: 90, Issue:2-3 Topics: Animals; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth; Pyrilamine; Receptors, Histamine	1983
Effects of histamine, H1- and H2-receptor antagonists on the activity of serotonergic neurons in the dorsal raphe nucleus. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2 Topics: Animals; Brain Stem; Cimetidine; Diphenhydramine; gamma-Aminobutyric Acid; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Metiamide; Neurons; Pyrilamine; Ranitidine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Serotonin; Synaptic Transmission	1983
The effect of antihistaminics on cataleptogenic action of analgesics and haloperidol. Polish journal of pharmacology and pharmacy, 1983, Volume: 35, Issue:4 Topics: Analgesics; Analgesics, Opioid; Animals; Catalepsy; Cimetidine; Diphenhydramine; Drug Interactions; Female; Haloperidol; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains	1983
Excitatory and inhibitory effects of H1-blockers on isolated bullfrog spinal cords. Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 271, Issue:1 Topics: Animals; Diphenhydramine; Gallopamil; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Motor Neurons; Neuromuscular Depolarizing Agents; Pyrilamine; Rana catesbeiana; Spinal Cord; Tetrodotoxin	1984
Inhibitory histamine H2-receptor in the guinea-pig urinary bladder. European journal of pharmacology, 1984, Oct-01, Volume: 105, Issue:1-2 Topics: Acetylcholine; Animals; Calcium; Choline; Cimetidine; Diphenhydramine; Electric Stimulation; Female; Guinea Pigs; Histamine; Imidazoles; Impromidine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Norepinephrine; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2; Scopolamine; Tetrodotoxin; Urinary Bladder	1984
Chick retinal pigment epithelium. A new culture system for studying H2-histamine receptors. FEBS letters, 1983, Dec-12, Volume: 164, Issue:2 Topics: Animals; Cells, Cultured; Chick Embryo; Cimetidine; Cyclic AMP; Diphenhydramine; Histamine; Methods; Pigment Epithelium of Eye; Pyrilamine; Receptors, Histamine; Receptors, Histamine H2	1983
Analgesic effect of histamine induced by intracerebral injection into mice. Agents and actions, 1984, Volume: 15, Issue:3-4 Topics: Analgesics; Animals; Benzoquinones; Cimetidine; Diphenhydramine; Electric Stimulation; Enkephalin, Leucine; Histamine; Histamine Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Promethazine; Pyrilamine; Quinones; Reaction Time	1984
Histamine H-1 receptors on rat peritoneal mast cells. Life sciences, 1982, Nov-01, Volume: 31, Issue:18 Topics: Aminopyridines; Animals; Ascitic Fluid; Binding, Competitive; Cimetidine; Diphenhydramine; Histamine; Male; Mast Cells; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1	1982
Trans-synaptic modulation of histamine H-1 receptor development in rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1981, Volume: 1, Issue:6 Topics: Animals; Animals, Newborn; Brain; Diphenhydramine; Female; Histamine; Hypothalamus; Pregnancy; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Synapses	1981
Antihistamine effect on synaptosomal uptake of serotonin, norepinephrine and dopamine. European journal of pharmacology, 1980, Jul-11, Volume: 65, Issue:1 Topics: Animals; Cimetidine; Diphenhydramine; Dopamine; Female; Histamine Antagonists; In Vitro Techniques; Kinetics; Norepinephrine; Promethazine; Pyrilamine; Rats; Serotonin; Synaptosomes	1980
Histamine-independent modulation of the neuropeptide Y-induced pressor response by alpha-trinositol in the pithed rat. Pharmacology & toxicology, 1994, Volume: 75, Issue:6 Topics: Animals; Antihypertensive Agents; Blood Pressure; Cimetidine; Decerebrate State; Diphenhydramine; Electric Stimulation; Heart Rate; Histamine Antagonists; Injections, Intravenous; Inositol Phosphates; Male; Neuropeptide Y; Phenylephrine; Pyrilamine; Rats; Rats, Sprague-Dawley; Vasopressins	1994
Liquid chromatography of antihistamines using post-column tris(2,2'-bipyridine) ruthenium(III) chemiluminescence detection. Journal of chromatography. A, 1994, Sep-23, Volume: 679, Issue:2 Topics: 2,2'-Dipyridyl; Brompheniramine; Chlorpheniramine; Chromatography, High Pressure Liquid; Diphenhydramine; Histamine H1 Antagonists; Luminescent Measurements; Organometallic Compounds; Pheniramine; Pyrilamine; Ruthenium; Spectrophotometry, Ultraviolet	1994
Involvement of central cholinergic muscarinic receptors and histamine H1 receptors in hyperglycemia induced by prostaglandin F2 alpha in rats. Neuroendocrinology, 1993, Volume: 57, Issue:1 Topics: Animals; Atropine; Dinoprost; Diphenhydramine; Histamine H1 Antagonists; Hyperglycemia; Injections, Intraventricular; Male; Muscarinic Antagonists; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Muscarinic	1993
Intestinal mucosal lymphocytes have H1 receptors: H1 antagonists reduce their proliferation and cytotoxicity. Cellular immunology, 1994, Volume: 156, Issue:1 Topics: Cell Division; Cytotoxicity, Immunologic; Diphenhydramine; Epithelium; Histamine; Humans; In Vitro Techniques; Intestinal Mucosa; Pyrilamine; Receptors, Histamine H1; Tumor Cells, Cultured	1994
Effects of Pasteurella haemolytica culture supernate on bovine tracheal smooth muscle. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 1993, Volume: 57, Issue:3 Topics: Animals; Atropine; Bacterial Toxins; Carbachol; Cattle; Culture Techniques; Cytotoxins; Diphenhydramine; Dose-Response Relationship, Drug; Exotoxins; Histamine; Mannheimia haemolytica; Muscle, Smooth; Pyrilamine; Trachea	1993
Cis-urocanic acid stimulates human peripheral blood monocyte prostaglandin E2 production and suppresses indirectly tumor necrosis factor-alpha levels. Journal of immunology (Baltimore, Md. : 1950), 1993, May-15, Volume: 150, Issue:10 Topics: Brompheniramine; Cells, Cultured; Cimetidine; Cyclic AMP; Dinoprostone; Diphenhydramine; Histamine; Humans; In Vitro Techniques; Interleukin-1; Interleukin-6; Lipopolysaccharides; Monocytes; Pyrilamine; Second Messenger Systems; Stereoisomerism; Tumor Necrosis Factor-alpha; Urocanic Acid	1993
EFFECTS OF HISTAMINE AND RELATED COMPOUNDS ON THE BOVINE IRIS DILATOR. Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:4 Topics: Analysis of Variance; Animals; Cattle; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Ileum; Iris; Lethal Dose 50; Male; Methylhistamines; Muscle Contraction; Muscle, Smooth; p-Methoxy-N-methylphenethylamine; Piperidines; Potassium; Pyrilamine; Ranitidine; Receptors, Histamine H1; Substance P	1996
Histamine enhanced the TNF-alpha-induced expression of E-selectin and ICAM-1 on vascular endothelial cells. Cellular immunology, 1996, Aug-01, Volume: 171, Issue:2 Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Dibenzoxepins; Diphenhydramine; Drug Interactions; E-Selectin; Endothelium, Vascular; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Intercellular Adhesion Molecule-1; Ketotifen; Olopatadine Hydrochloride; Pyrilamine; Ranitidine; Tumor Necrosis Factor-alpha; Umbilical Veins	1996
Histamine H1 receptor activation blocks two classes of potassium current, IK(rest) and IAHP, to excite ferret vagal afferents. The Journal of physiology, 1997, Sep-15, Volume: 503 ( Pt 3) Topics: Action Potentials; Animals; Diphenhydramine; Electric Conductivity; Ferrets; Histamine; Histamine Agonists; Histamine H1 Antagonists; Impromidine; Male; Methylhistamines; Neurons, Afferent; Nodose Ganglion; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Pyrilamine; Receptors, Histamine H1; Thiazoles; Vagus Nerve	1997
In vivo studies with low doses of levocabastine and diphenhydramine, but not pyrilamine, antagonize neurotensin-mediated antinociception. Brain research, 1998, Mar-16, Volume: 787, Issue:1 Topics: Animals; Body Temperature Regulation; Diphenhydramine; Drug Evaluation, Preclinical; Histamine H1 Antagonists; Male; Mice; Neurotensin; Pain; Piperidines; Pyrilamine; Rats; Rats, Sprague-Dawley	1998
Slow wave sleep-inducing effects of first generation H1-antagonists. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:10 Topics: Animals; Azepines; Chlorpheniramine; Diphenhydramine; Electroencephalography; Histamine H1 Antagonists; Hypnotics and Sedatives; Male; Pyrilamine; Rats; Rats, Wistar; Sleep	1999
The role of potassium channels in antihistamine analgesia. Neuropharmacology, 1999, Volume: 38, Issue:12 Topics: Animals; Diphenhydramine; Drug Synergism; Histamine H1 Antagonists; Ion Channel Gating; Male; Mice; Oligonucleotides, Antisense; Pain Measurement; Pertussis Toxin; Potassium Channels; Promethazine; Pyrilamine; Virulence Factors, Bordetella	1999
Effects of histamine and related compounds on regional cerebral blood flow in rats. Methods and findings in experimental and clinical pharmacology, 1999, Volume: 21, Issue:9 Topics: Animals; Benzothiazoles; Blood Pressure; Brain Chemistry; Dimaprit; Diphenhydramine; Drug Interactions; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Male; Phenoxypropanolamines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Regional Blood Flow; Thiazoles; Time Factors	1999
MDMA ('ecstasy') enhances basal acetylcholine release in brain slices of the rat striatum. The European journal of neuroscience, 2000, Volume: 12, Issue:4 Topics: Acetylcholine; Animals; Antiparkinson Agents; Corpus Striatum; Diphenhydramine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Histamine H1 Antagonists; In Vitro Techniques; Male; Methysergide; N-Methyl-3,4-methylenedioxyamphetamine; Pyrilamine; Quinoxalines; Rats; Rats, Sprague-Dawley; Serotonin Agents; Serotonin Antagonists; Tritium	2000
Effects of H1 antagonists on cholinomimetic-induced tremulous jaw movements: studies of diphenhydramine, doxepin, and mepyramine. Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:4 Topics: Animals; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Cholinergic Agents; Clozapine; Diphenhydramine; Dose-Response Relationship, Drug; Doxepin; Histamine H1 Antagonists; Jaw; Male; Movement; Olanzapine; Pirenzepine; Pyrilamine; Rats; Rats, Sprague-Dawley; Receptors, Histamine H1; Receptors, Muscarinic; Tacrine; Tremor	2000
Effects of vasopressin on histamine H(1) receptor antagonist-induced spatial memory deficits in rats. European journal of pharmacology, 2001, Jul-06, Volume: 423, Issue:2-3 Topics: Animals; Arginine Vasopressin; Brain; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Male; Maze Learning; Memory Disorders; Pyrilamine; Rats; Rats, Wistar; Scopolamine; Vasopressins	2001
Effect of H1-antagonists on spatial memory deficit evaluated by 8-arm radial maze in rats. Acta pharmacologica Sinica, 2001, Volume: 22, Issue:7 Topics: Animals; Cognition; Dibenzazepines; Diphenhydramine; Histamine H1 Antagonists; Imidazoles; Male; Maze Learning; Memory; Memory Disorders; Pyrilamine; Rats; Rats, Wistar; Tacrine	2001
Antihistamine antinociception is mediated by Gi-protein activation. Neuroscience, 2002, Volume: 109, Issue:4 Topics: Analgesics; Animals; Behavior, Animal; Central Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Interactions; GTP-Binding Protein alpha Subunits, Gi-Go; Histamine H1 Antagonists; Male; Mice; Motor Activity; Neurons; Nociceptors; Oligodeoxyribonucleotides, Antisense; Pain; Pain Threshold; Promethazine; Pyrilamine; Receptors, Histamine H1; Synaptic Transmission	2002
Murine tumor necrosis factor-alpha sensitizes plasma corticosterone activity and the manifestation of shock: modulation by histamine. Journal of neuroimmunology, 2002, Volume: 131, Issue:1-2 Topics: Animals; Anti-Inflammatory Agents; Biogenic Monoamines; Cimetidine; Corticosterone; Dexamethasone; Diphenhydramine; Histamine; Histamine Antagonists; Hypothalamus; Male; Mice; Pyrilamine; Receptors, Histamine; Shock; Tumor Necrosis Factor-alpha	2002
Epileptogenic activity induced by histamine H(1) antagonists in amygdala-kindled rats. Brain research, 2003, Nov-21, Volume: 991, Issue:1-2 Topics: Amygdala; Animals; Cetirizine; Diphenhydramine; Electroencephalography; Epilepsy; Histamine H1 Antagonists; Injections, Intraperitoneal; Ketotifen; Kindling, Neurologic; Loratadine; Male; Pyrilamine; Rats; Rats, Wistar	2003
Ginkgo biloba extract improves spatial memory in rats mainly but not exclusively via a histaminergic mechanism. Brain research, 2007, Jan-19, Volume: 1129, Issue:1 Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Diphenhydramine; Donepezil; Ginkgo biloba; Histamine; Histamine H1 Antagonists; Indans; Male; Maze Learning; Memory; Memory Disorders; Muscarinic Antagonists; Neural Pathways; Nootropic Agents; Piperidines; Plant Extracts; Pyrilamine; Rats; Rats, Wistar; Scopolamine; Synaptic Transmission; Treatment Outcome	2007
Antihistamine mepyramine directly inhibits KCNQ/M channel and depolarizes rat superior cervical ganglion neurons. Neuropharmacology, 2008, Volume: 54, Issue:4 Topics: Animals; Animals, Newborn; Cells, Cultured; Diphenhydramine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Histamine H1 Antagonists; Humans; Indoles; KCNQ Potassium Channels; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Pyridines; Pyrilamine; Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Transfection	2008
Super-additive interaction of the reinforcing effects of cocaine and H1-antihistamines in rhesus monkeys. Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:4 Topics: Animals; Cocaine; Conditioning, Operant; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Histamine H1 Antagonists; Macaca mulatta; Male; Pyrilamine; Reinforcement Schedule	2009
Effects of histamine H(1) receptor antagonists on delayed spatial win-shift task in rats. European journal of pharmacology, 2010, Apr-10, Volume: 631, Issue:1-3 Topics: Animals; Behavior, Animal; Choice Behavior; Diphenhydramine; Dose-Response Relationship, Drug; Hippocampus; Histamine H1 Antagonists; Male; Maze Learning; Memory; Muscarinic Antagonists; Pyrilamine; Rats; Rats, Wistar; Receptors, Histamine H1; Retention, Psychology; Scopolamine; Space Perception; Time Factors	2010
Nicotine transport in lung and non-lung epithelial cells. Life sciences, 2017, Nov-01, Volume: 188 Topics: Biological Transport; Carnitine; Cells, Cultured; Diphenhydramine; Drug Interactions; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Lung; Nicotine; Pyrilamine; Temperature; Tetraethylammonium; Time Factors; Tritium; Valinomycin	2017
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats. Pharmacology research & perspectives, 2021, Volume: 9, Issue:5 Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine	2021