diphenhydramine and procainamide

diphenhydramine has been researched along with procainamide in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19906 (24.00)18.7374
1990's0 (0.00)18.2507
2000's11 (44.00)29.6817
2010's8 (32.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Hashimoto, N; Nezu Ji, J; Nikaido, H; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Akazawa, M; Inui, K; Masuda, S; Okuda, M; Saito, H; Urakami, Y1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Nagashima, R; Nishikawa, T; Tobita, M1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Alimuddin, M; Bulloch, D; Dahl, R; Grant, D; Lee, N; Peacock, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Allen, JW; Black, PN; DiRusso, CC; Tu, B; Wase, N1
Durie, BG; Peters, GA1
Lawson, JW1
Motoyoshi, K; Suzuki, M1
Akera, T; Brody, TM; Kondo, H; Temma, K1
ALTMAN, KA1
Fujii, N; Hashimoto, Y; Horie, A; Inoue, H; Ishida, K; Nishimura, M; Nozawa, T; Taguchi, M1

Reviews

1 review(s) available for diphenhydramine and procainamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

24 other study(ies) available for diphenhydramine and procainamide

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2.
    Molecular pharmacology, 2001, Volume: 59, Issue:2

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Carnitine; Carrier Proteins; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Humans; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Tetraethylammonium; Tissue Distribution; Tritium

2001
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Distinct characteristics of organic cation transporters, OCT1 and OCT2, in the basolateral membrane of renal tubules.
    Pharmaceutical research, 2001, Volume: 18, Issue:11

    Topics: Animals; Cell Line; Dogs; Kidney; Kidney Tubules; Kinetics; Membranes; Nephrons; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Substrate Specificity; Tetraethylammonium; Transfection

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Determination of log D via automated microfluidic liquid-liquid extraction.
    Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16

    Topics: Automation; Biopharmaceutics; Microfluidic Analytical Techniques; Pharmacokinetics

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae.
    Plant physiology, 2017, Volume: 174, Issue:4

    Topics: Biosynthetic Pathways; Chlamydomonas reinhardtii; Chlorophyta; Gas Chromatography-Mass Spectrometry; High-Throughput Screening Assays; Lipid Metabolism; Lipids; Metabolome; Metabolomics; Multivariate Analysis; Photosynthesis; Pigments, Biological; Plant Proteins; Starch

2017
Cardiac arrhythmia following a hornet sting.
    Annals of allergy, 1970, Volume: 28, Issue:12

    Topics: Adult; Cardiac Complexes, Premature; Creatine Kinase; Diphenhydramine; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Insect Bites and Stings; Male; Procainamide

1970
Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 160, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Chloroform; Diphenhydramine; Electrocardiography; Female; Heart Rate; Methods; Methoxamine; Mice; Naphazoline; Oxyphenonium; Papaverine; Phenylephrine; Procainamide; Propranolol; Quinidine; Quinolines; Reserpine; Ventricular Fibrillation

1968
[Pharmacological studies of scornidin, an extract from Allium plants].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1966, May-20, Volume: 62, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Blood Circulation; Diphenhydramine; Dogs; Epinephrine; Glycosides; Guinea Pigs; Histamine; In Vitro Techniques; Mice; Muscle, Smooth; Norepinephrine; Physostigmine; Plants, Medicinal; Procainamide; Rabbits; Respiration; Salivary Glands; Tachyphylaxis

1966
Positive inotropic action of p-chloromercuribenzoate in isolated guinea-pig heart: influence of membrane stabilizing agents.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3

    Topics: Animals; Cell Membrane; Chloromercuribenzoates; Diphenhydramine; Drug Interactions; Ethylmaleimide; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; p-Chloromercuribenzoic Acid; Phenobarbital; Procainamide; Propranolol; Stereoisomerism

1981
VENTRICULAR FIBRILLATION.
    JAMA, 1964, Nov-23, Volume: 190

    Topics: Cardiovascular Diseases; Diphenhydramine; Drug Therapy; Electrocardiography; Humans; Isoproterenol; Procainamide; Syncope; Ventricular Fibrillation

1964
Variability of bioavailability and intestinal absorption characteristics of bisoprolol.
    Drug metabolism and pharmacokinetics, 2013, Volume: 28, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Asian People; Biological Availability; Bisoprolol; Cardiovascular Diseases; Cells, Cultured; Diphenhydramine; Drug Interactions; Epithelial Cells; Female; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Middle Aged; Procainamide; Quinidine; Temperature

2013