diphenhydramine and physostigmine

diphenhydramine has been researched along with physostigmine in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199027 (69.23)18.7374
1990's3 (7.69)18.2507
2000's4 (10.26)29.6817
2010's4 (10.26)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Caron, G; Ermondi, G1
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lee, JH; Poppers, PJ; Turndorf, H1
Borkenstein, M; Haidvogl, M1
Kai-Håkon, C1
Parness, J; Zlotkin, E1
Hopfe, T; Koppel, C; Menzel, J1
Betti, R; Casanueva, FF; Cella, SG; Müller, EE1
Cox, PM; D'Amato, SL; Rinder, CS; Rinder, HM1
Abdul-Latif, AR; Al-Kassim, NA; Mohammad, FK1
Beltagy, YA; Ibrahim el-S, A; Rida, SM1
Bell, S; Jhamandas, K; Sutak, M1
Kirsten, EB; Schoener, EP1
Rossini, L; Valeri, P1
Khairallah, PA; Page, IH; Türker, RK1
Barnett, A; Malick, JB; Taber, RI1
Kabeno, H; Kobayashi, Y; Tachibana, K1
Bhatnagar, SP1
Vaillant, GE1
Cohen, S; Lipshutz, W; Tuch, AF1
Bhargava, LP; Dandiya, PC1
Takagi, K; Takayanagi, I1
Motoyoshi, K; Suzuki, M1
Primor, N1
Bohm, L; Drenck, NE; von Staffeldt, H1
Bartolini, A; Galeotti, N; Ghelardini, C1
Arnholz, D; Arnold, SM; Garyfallou, GT; Heard, K1
Engebretsen, KM; Harris, CR; Holger, JS1
Padilla, RB; Pollack, ML1
BEAVER, WT; RIKER, WF1
WADA, JA1
TAKIUCHI, T1
AZOKWU, P; FUELGRAFF, G; SCHMIDT, L1
FUELGRAFF, G; SCHMIDT, L1
Baroke, E; Kielstein, JT; Kühn-Velten, WN; Schmidt, JJ; Strunk, AK; Wiesner, O1
Baker, K; Heard, K; Janis, GC; Leonard, J; Mistry, RD; Ng, P; Wang, GS1

Reviews

1 review(s) available for diphenhydramine and physostigmine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for diphenhydramine and physostigmine

ArticleYear
A randomized trial comparing physostigmine vs lorazepam for treatment of antimuscarinic (anticholinergic) toxidrome.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:8

    Topics: Adolescent; Akathisia, Drug-Induced; Anti-Anxiety Agents; Delirium; Diphenhydramine; Double-Blind Method; Female; Humans; Length of Stay; Lorazepam; Male; Muscarinic Antagonists; Physostigmine; Treatment Outcome

2021

Other Studies

37 other study(ies) available for diphenhydramine and physostigmine

ArticleYear
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Physostigmine reversal of antihistamine-induced excitement and depression.
    Anesthesiology, 1975, Volume: 43, Issue:6

    Topics: Adolescent; Aged; Brain; Depression; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Male; Physostigmine; Psychomotor Disorders

1975
Treatment of ingestion of diphenhydramine.
    The Journal of pediatrics, 1978, Volume: 92, Issue:1

    Topics: Diphenhydramine; Fever; Gastric Lavage; Humans; Infant; Male; Phenytoin; Physostigmine; Respiration, Artificial

1978
[Antihistamine poisoning. Treatment with physostigmine].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1977, Sep-10, Volume: 97, Issue:25

    Topics: Child, Preschool; Diphenhydramine; Female; Humans; Physostigmine

1977
Action of the toxic skin secretion of the flatfish Pardachirus marmoratus on the guinea-pig ileum.
    Toxicon : official journal of the International Society on Toxinology, 1976, Volume: 14, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Diphenhydramine; Fishes; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Marine Toxins; Muscle Contraction; Physostigmine; Tetrodotoxin

1976
Central anticholinergic syndrome after ofloxacin overdose and therapeutic doses of diphenhydramine and chlormezanone.
    Journal of toxicology. Clinical toxicology, 1990, Volume: 28, Issue:2

    Topics: Adolescent; Chlormezanone; Diphenhydramine; Drug Synergism; Female; Humans; Ofloxacin; Parasympatholytics; Physostigmine; Psychoses, Substance-Induced

1990
Activation of the cholinergic system and growth hormone release in the dog: functional interactions with other neurotransmitters.
    Acta endocrinologica, 1985, Volume: 108, Issue:1

    Topics: Animals; Behavior, Animal; Cimetidine; Clemastine; Diphenhydramine; Dogs; Domperidone; Female; Fenfluramine; Growth Hormone; Male; Metergoline; Naloxone; Phentolamine; Physostigmine; Pimozide; Pizotyline; Propranolol; Radioimmunoassay; Receptors, Cholinergic; Synaptic Transmission

1985
Survival in complicated diphenhydramine overdose.
    Critical care medicine, 1988, Volume: 16, Issue:11

    Topics: Adult; Arrhythmias, Cardiac; Coma; Diphenhydramine; Female; Fever; Humans; Nonprescription Drugs; Physostigmine; Status Epilepticus

1988
Interaction of diphenhydramine with cholinesterase inhibitors in mice.
    Toxicology letters, 1987, Volume: 37, Issue:3

    Topics: Animals; Cholinesterase Inhibitors; Diphenhydramine; Drug Synergism; Lethal Dose 50; Male; Mice; Neostigmine; Physostigmine

1987
Tetraphenylboron as direct titrant for diphasic determination of some organic bases.
    Die Pharmazie, 1973, Volume: 28, Issue:3

    Topics: Alkanes; Benzimidazoles; Boron Compounds; Chemistry Techniques, Analytical; Cinchona; Cyproheptadine; Diphenhydramine; Imidazoles; Meclizine; Methods; Methylphenidate; Oxyphenonium; Papaverine; Penicillin G; Physostigmine; Piperidines; Plants, Medicinal; Quaternary Ammonium Compounds; Strychnine; Tetracaine

1973
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms.
    European journal of pharmacology, 1973, Volume: 24, Issue:3

    Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline

1973
Action of anticholinergic and related agents on single vestibular neurones.
    Neuropharmacology, 1973, Volume: 12, Issue:12

    Topics: Alkaloids; Animals; Atropa belladonna; Atropine; Blood Pressure; Cats; Decerebrate State; Diphenhydramine; Electric Stimulation; Electrodes; Histamine H1 Antagonists; Indoles; Neostigmine; Neurons; Parasympatholytics; Physostigmine; Plants, Medicinal; Plants, Toxic; Scopolamine; Semicircular Canals

1973
[Effect of some drugs on the adenosine triphosphatase of microsomes of the bovine brain and kidney].
    Bollettino della Societa italiana di biologia sperimentale, 1966, Oct-31, Volume: 42, Issue:20

    Topics: Adenosine Triphosphatases; Animals; Brain; Cattle; Diphenhydramine; Kidney; Microsomes; Ouabain; Physostigmine; Tubocurarine

1966
Some properties of prostaglandin E1 action on muscle.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 169, Issue:2

    Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Autonomic Agents; Bradykinin; Cats; Decamethonium Compounds; Diphenhydramine; Epinephrine; Histamine; In Vitro Techniques; Lysergic Acid Diethylamide; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxytocin; Phentolamine; Physostigmine; Propranolol; Prostaglandins; Rabbits; Reserpine; Serotonin; Tubocurarine; Tyramine; Vasopressins

1967
Effects of antihistamines on isolation-induced fighting in mice.
    Psychopharmacologia, 1971, Volume: 19, Issue:4

    Topics: Aggression; Animals; Behavior, Animal; Cyproheptadine; Diphenhydramine; Histamine H1 Antagonists; Humans; Ileum; Male; Mice; Motor Activity; Physostigmine; Promethazine; Social Isolation; Tetrabenazine

1971
Studies on gastrointestinal hormones. X. Effects of tetragastrin on gastric secretion and isolated smooth muscles.
    Japanese journal of pharmacology, 1973, Volume: 23, Issue:2

    Topics: Animals; Atropine; Cholinesterase Inhibitors; Diphenhydramine; Epinephrine; Gastric Mucosa; Gastrins; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Physostigmine; Rats; Semicarbazides

1973
Action of some centrally active drugs and heavy metals on in vitro oxidation of dopamine by rat brain tissue.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:11

    Topics: Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Brain; Cadmium; Central Nervous System; Chlorpromazine; Choline; Diphenhydramine; Dopamine; Female; In Vitro Techniques; Iproniazid; Lead; Melanins; Metals; Methylmercury Compounds; Mitochondria; Oxidation-Reduction; Physostigmine; Rats; Serotonin; Sucrose; Time Factors; Tranquilizing Agents

1972
A comparison of antagonists of physostigmine-induced suppression of behavior.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:3

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Chlorpromazine; Columbidae; Diphenhydramine; Haplorhini; Imipramine; Male; Mecamylamine; Muscles; Parasympatholytics; Physostigmine; Scopolamine; Trihexyphenidyl

1967
A comparison of the site of action of gastrin I on lower esophageal sphincter and antral circular smooth muscle.
    Gastroenterology, 1971, Volume: 61, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Binding Sites; Culture Techniques; Diphenhydramine; Esophagogastric Junction; Gastrins; Hemicholinium 3; Hexamethonium Compounds; Histamine; Methysergide; Muscle Contraction; Muscle, Smooth; Norepinephrine; Opossums; Pentolinium Tartrate; Phentolamine; Physostigmine; Propranolol; Scopolamine; Stomach; Tetrodotoxin

1971
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1

    Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine Oxidase Inhibitors; Nialamide; Nicotine; Nortropanes; Pargyline; Parkinson Disease; Parkinson Disease, Secondary; Perphenazine; Phenelzine; Physostigmine; Rats; Scopolamine; Sulfonic Acids; Tolazoline; Tremor; Tremorine; Trihexyphenidyl; Tryptamines

1968
Effects of aromatic nitrocompounds and phenolderivatives on the cholinergic nerve ending of smooth muscle and skeletal muscle.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:2

    Topics: Animals; Anura; Atropine; Benzoates; Diphenhydramine; Electrokymography; Guinea Pigs; Hexamethonium Compounds; Histamine; In Vitro Techniques; Intestine, Small; Morphine; Muscle, Smooth; Nerve Endings; Nitrophenols; Parasympathetic Nervous System; Phenols; Physostigmine; Picrates

1965
[Pharmacological studies of scornidin, an extract from Allium plants].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1966, May-20, Volume: 62, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Blood Circulation; Diphenhydramine; Dogs; Epinephrine; Glycosides; Guinea Pigs; Histamine; In Vitro Techniques; Mice; Muscle, Smooth; Norepinephrine; Physostigmine; Plants, Medicinal; Procainamide; Rabbits; Respiration; Salivary Glands; Tachyphylaxis

1966
Pardaxin produces postjunctional muscle contraction in guinea-pig intestinal smooth muscle.
    British journal of pharmacology, 1984, Volume: 82, Issue:1

    Topics: Acetylcholine; Animals; Diphenhydramine; Drug Interactions; Electric Stimulation; Fish Venoms; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Physostigmine; Serotonin; Spider Venoms; Substance P

1984
[Diphenhydramine poisoning. Anticholinergic manifestations treated with physostigmine salicylate].
    Ugeskrift for laeger, 1980, Apr-28, Volume: 142, Issue:18

    Topics: Adolescent; Adult; Diphenhydramine; Female; Humans; Male; Physostigmine; Salicylates

1980
Effect of pertussis toxin on morphine, diphenhydramine, baclofen, clomipramine and physostigmine antinociception.
    European journal of pharmacology, 1996, Jul-18, Volume: 308, Issue:2

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Baclofen; Cholinesterase Inhibitors; Clomipramine; Diphenhydramine; Drug Antagonism; GABA Agonists; Histamine H1 Antagonists; Injections, Intraventricular; Male; Mice; Morphine; Pain Measurement; Pertussis Toxin; Physostigmine; Virulence Factors, Bordetella

1996
Two siblings poisoned with diphenhydramine: a case of factitious disorder by proxy.
    Annals of emergency medicine, 1998, Volume: 32, Issue:2

    Topics: Antidotes; Charcoal; Child; Cholinesterase Inhibitors; Diphenhydramine; Female; Hospitalization; Humans; Hypnotics and Sedatives; Male; Munchausen Syndrome by Proxy; Physostigmine; Sorption Detoxification

1998
Physostigmine, sodium bicarbonate, or hypertonic saline to treat diphenhydramine toxicity.
    Veterinary and human toxicology, 2002, Volume: 44, Issue:1

    Topics: Animals; Antidotes; Diphenhydramine; Male; Physostigmine; Rats; Rats, Sprague-Dawley; Seizures; Sodium Bicarbonate; Sodium Chloride

2002
The use of physostigmine in diphenhydramine overdose.
    The American journal of emergency medicine, 2002, Volume: 20, Issue:6

    Topics: Adult; Anti-Allergic Agents; Cholinesterase Inhibitors; Diphenhydramine; Drug Overdose; Humans; Male; Physostigmine; Tachycardia, Sinus

2002
The quantitative evaluation of autonomic drugs on the isolated eye.
    The Journal of pharmacology and experimental therapeutics, 1962, Volume: 138

    Topics: Acetylcholine; Ammonium Compounds; Atropine; Autonomic Agents; Diphenhydramine; Epinephrine; Eye; Hexamethonium Compounds; Histamine; Humans; Isoflurophate; Isoproterenol; Mecamylamine; Methacholine Compounds; Miotics; Neostigmine; Norepinephrine; Parasympathomimetics; Phenylephrine; Physostigmine; Pilocarpine; Quaternary Ammonium Compounds

1962
Behavioral and EEG correlates of modified levels of brain neurohumoral agents.
    Journal of neuropsychiatry, 1963, Volume: 4

    Topics: Atropine; Behavior; Brain; Dihydroxyphenylalanine; Diphenhydramine; Electroencephalography; Iproniazid; Neurotransmitter Agents; Physostigmine; Reserpine; Serotonin

1963
ACTION OF SEVERAL ANTI-HISTAMINICS ON THE ISOLATED RAT PHRENIC-DIAPHRAGM PREPARATION.
    Japanese journal of pharmacology, 1964, Volume: 14

    Topics: Abdominal Muscles; Anti-Allergic Agents; Chlorpheniramine; Diaphragm; Diphenhydramine; Electrophysiology; Histamine H1 Antagonists; Muscle Relaxants, Central; Neuromuscular Junction; Pharmacology; Phrenic Nerve; Physostigmine; Promethazine; Rats; Research; Tripelennamine; Tubocurarine

1964
[ON ATROPINE-RESISTANT NEUROMUSCULAR TRANSMISSION IN THE CAT PELVIC NERVE-COLON PREPARATION].
    Archives internationales de pharmacodynamie et de therapie, 1964, Jun-01, Volume: 149

    Topics: Acetylcholine; Atropine; Biphenyl Compounds; Bis-Trimethylammonium Compounds; Cats; Colon; Diphenhydramine; Ganglionic Blockers; Histamine; Neuromuscular Junction; Papaverine; Pharmacology; Phentolamine; Physostigmine; Research; Selective Serotonin Reuptake Inhibitors; Serotonin; Spinal Nerves; Sympatholytics

1964
[RESEARCH ON ATROPINE-RESISTANT TRANSMISSION IN THE CAT PELVIC NERVE-COLON PREPARATION IN VITRO].
    Archives internationales de pharmacodynamie et de therapie, 1964, Jun-01, Volume: 149

    Topics: Acetylcholine; Atropine; Bradykinin; Cats; Colon; Diphenhydramine; Histamine; In Vitro Techniques; Neuromuscular Junction; Pharmacology; Physostigmine; Research; Spinal Nerves

1964
Saving two lives with one dialysis treatment.
    Clinical nephrology, 2015, Volume: 84, Issue:2

    Topics: Bipolar Disorder; Cholinesterase Inhibitors; Diphenhydramine; Drug Overdose; Female; Humans; Hypnotics and Sedatives; Physostigmine; Renal Dialysis; Suicide, Attempted; Young Adult

2015