diphenhydramine and phenylephrine

diphenhydramine has been researched along with phenylephrine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199015 (55.56)18.7374
1990's3 (11.11)18.2507
2000's5 (18.52)29.6817
2010's1 (3.70)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Anttila, P; Lücke, C; Westermann, E1
Fernandez-Alfonso, MS; Marín, J; Reviriego, J1
Chang, KS; Tanz, RD; Weller, TS1
Liou, SY; Shibata, S; Ueki, S1
Murad, F1
Hudgins, PM; Stubbins, JF1
Abdine, H; Soliman, SA; Zakhari, NA1
Timperman, J; Verbauwhede, W1
Kammerl, E; Schlemmer, W1
De Fabrizio, F1
Dowdy, EG; Yamanaka, I1
Lawson, JW1
Akins, CW; Moss, J; Philbin, DM; Rosenberger, JL; Rosow, CE1
Carrier, GO; Kirby, ML; White, RE1
Edvinsson, L; Hedner, T; Sun, X1
Hushcha, TO; Luik, AI; Mischenko, NI; Mogilevich, SE1
Gomez, MR; Martínez, LD; Olsina, RA; Silva, MF1
Goicoechea, HC; Mantovani, VE; Marchesini, AF; Robles, JC; Williner, MR1
Chen, IM; Cheng, CY; Lin, CH; Lin, MS; Lin, PR; Lin, YH; Tsai, MC1
BEAVER, WT; RIKER, WF1
ROSSIER, M1
Baskurt, OK; Batu, O; Meiselman, HJ; Ozdem, SS; Tayfun, F; Yalcin, O1
Hammad, SF; Saad Radwan, A; Salim, MM1
Archakam, SC; Koganti, B; Palur, K1
Banner, W; Bond, GR; Dart, RC; Delva-Clark, H; Green, JL; Halmo, LS; Kauffman, RE; Palmer, RB; Paul, IM; Rapp-Olsson, M; Reynolds, KM; Wang, GS1

Trials

1 trial(s) available for diphenhydramine and phenylephrine

ArticleYear
Histamine release with intravenous narcotics: protective effects of H1 and H2-receptor antagonists.
    Klinische Wochenschrift, 1982, Sep-01, Volume: 60, Issue:17

    Topics: Cimetidine; Diphenhydramine; Double-Blind Method; Fentanyl; Hemodynamics; Histamine Release; Humans; Morphine; Phenylephrine; Random Allocation

1982

Other Studies

26 other study(ies) available for diphenhydramine and phenylephrine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Stimulation of adenylate cyclase of guinea pig gastric mucosa by histamine, sodium fluoride and 5'-guanylylimidodiphosphate and inhibition by histamine H1- and H2-receptor antagonists in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 296, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Diphenhydramine; Fluorides; Gastric Mucosa; Guanine Nucleotides; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Isoproterenol; Metiamide; Pentagastrin; Phenylephrine; Pyrilamine; Sodium Fluoride

1976
Actions of vasoactive drugs on human placental vascular smooth muscle.
    General pharmacology, 1990, Volume: 21, Issue:5

    Topics: Arteries; Clonidine; Diphenhydramine; Dopamine; Female; Histamine; Humans; In Vitro Techniques; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Placenta; Pregnancy; Regional Blood Flow; Serotonin; Veins

1990
Histamine relaxation of aortic rings from diabetic rats.
    Agents and actions, 1989, Volume: 28, Issue:1-2

    Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Diphenhydramine; Endothelium, Vascular; Histamine; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Phenylephrine; Rats; Rats, Inbred Strains; Time Factors

1989
Effect of monoamines on field potentials in the suprachiasmatic nucleus of slices of hypothalamus of the rat evoked by stimulation of the optic nerve.
    Neuropharmacology, 1986, Volume: 25, Issue:9

    Topics: Animals; Circadian Rhythm; Diphenhydramine; Dopamine; Electrophysiology; Evoked Potentials; Histamine; Isoproterenol; Male; Norepinephrine; Optic Nerve; Phenoxybenzamine; Phentolamine; Phenylephrine; Rats; Rats, Inbred Strains; Serotonin; Suprachiasmatic Nucleus

1986
Mechanism of action of some bronchodilators. Cyclic nucleotide metabolism in tracheal preparations.
    The American review of respiratory disease, 1974, Volume: 110, Issue:6 Pt 2

    Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Atropine; Bronchodilator Agents; Carbachol; Choline; Cyclic AMP; Cyclic GMP; Diphenhydramine; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Phenoxybenzamine; Phenylephrine; Practolol; Propranolol; Prostaglandins; Serotonin; Theophylline; Time Factors; Trachea

1974
Pharmacologic evaluation of a new series of cholinergic antagonists containing an agonist moiety.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 166, Issue:2

    Topics: Acetylcholine; Animals; Aorta; Atropine; Benzilates; Carbachol; Chemical Phenomena; Chemistry; Chlorides; Diphenhydramine; Female; Histamine H1 Antagonists; Jejunum; Muscle Contraction; Phenylephrine; Quaternary Ammonium Compounds; Rabbits; Receptors, Drug

1969
Indirect nonaqueous titration of hydrochlorides of nitrogenous bases.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:11

    Topics: Acetates; Chlorpromazine; Diphenhydramine; Ephedrine; Hydrochloric Acid; Indicators and Reagents; Mercury; Methods; Papaverine; Phenylephrine; Potentiometry; Quinine

1974
Toxic epidermal necrolysis (Lyell syndrome) and its medico-legal implications.
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1972, Nov-28, Volume: 71, Issue:2

    Topics: Child, Preschool; Diphenhydramine; Female; Forensic Medicine; Humans; Phenylbutazone; Phenylephrine; Stevens-Johnson Syndrome; Syndrome

1972
Application of quantitative thin-layer chromatography in drug assay and stability testing. Determination of codeine phosphate, noscapine, diphenhydramine hydrochloride, phenylephrine hydrochloride, caffeine, etofyllin, phenobarbital and thiamine hydrochlo
    Journal of chromatography, 1973, Jul-18, Volume: 82, Issue:1

    Topics: Autoanalysis; Caffeine; Chromatography, Thin Layer; Codeine; Diphenhydramine; Drug Combinations; Drug Stability; Methods; Noscapine; Pharmaceutical Preparations; Phenobarbital; Phenylephrine; Spectrum Analysis; Theophylline; Thiamine

1973
Analysis of acetaminophen, phenylephrine hydrochloride, diphenhydramine hydrochloride, and ascorbic acid in a capsule preparation.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:1

    Topics: Acetaminophen; Alginates; Alkaloids; Ascorbic Acid; Capsules; Chromatography, Ion Exchange; Diphenhydramine; Hydrogen-Ion Concentration; Phenylephrine; Solutions; Spectrophotometry, Ultraviolet; Starch

1974
The effects of ketamine on spiral-cut strips of rabbit aorta.
    Anesthesiology, 1974, Volume: 40, Issue:3

    Topics: Animals; Aorta; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Isoproterenol; Ketamine; Lidocaine; Muscle Contraction; Muscle, Smooth; Phentolamine; Phenylephrine; Procaine; Propranolol; Quinidine; Rabbits

1974
Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 160, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Chloroform; Diphenhydramine; Electrocardiography; Female; Heart Rate; Methods; Methoxamine; Mice; Naphazoline; Oxyphenonium; Papaverine; Phenylephrine; Procainamide; Propranolol; Quinidine; Quinolines; Reserpine; Ventricular Fibrillation

1968
Histamine-induced relaxation of rat aorta. Importance of H1 receptor and vascular endothelium.
    Blood vessels, 1984, Volume: 21, Issue:4

    Topics: Animals; Aorta, Thoracic; Binding, Competitive; Cimetidine; Diphenhydramine; Endothelium; Histamine; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Rats; Receptors, Histamine; Receptors, Histamine H1

1984
Histamine-independent modulation of the neuropeptide Y-induced pressor response by alpha-trinositol in the pithed rat.
    Pharmacology & toxicology, 1994, Volume: 75, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cimetidine; Decerebrate State; Diphenhydramine; Electric Stimulation; Heart Rate; Histamine Antagonists; Injections, Intravenous; Inositol Phosphates; Male; Neuropeptide Y; Phenylephrine; Pyrilamine; Rats; Rats, Sprague-Dawley; Vasopressins

1994
Study of human serum albumin structure by dynamic light scattering: two types of reactions under different pH and interaction with physiologically active compounds.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 1998, Volume: 54A, Issue:10

    Topics: Atropine; Carbachol; Chlorpromazine; Clonidine; Diphenhydramine; Humans; Hydrogen-Ion Concentration; Isoproterenol; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Phenylephrine; Propranolol; Protein Binding; Scattering, Radiation; Serum Albumin; Yohimbine

1998
Simultaneous determination of dextromethorphan, diphenhydramine and phenylephrine in expectorant and decongestant syrups by capillary electrophoresis.
    Journal of pharmaceutical and biomedical analysis, 2002, Oct-15, Volume: 30, Issue:3

    Topics: Chemistry, Pharmaceutical; Dextromethorphan; Diphenhydramine; Electrophoresis, Capillary; Expectorants; Nasal Decongestants; Phenylephrine

2002
Simultaneous determination of naphazoline, diphenhydramine and phenylephrine in nasal solutions by capillary electrophoresis.
    Journal of pharmaceutical and biomedical analysis, 2003, Feb-05, Volume: 31, Issue:1

    Topics: Administration, Intranasal; Algorithms; Diphenhydramine; Electrophoresis, Capillary; Excipients; Hydrogen-Ion Concentration; Indicators and Reagents; Naphazoline; Pharmaceutical Solutions; Phenylephrine; Reproducibility of Results; Spectrophotometry, Ultraviolet

2003
A new isoquinolinone derivative with noble vasorelaxation activity.
    Pharmacology, 2003, Volume: 67, Issue:4

    Topics: Acetylcholine; Adrenergic Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Atropine; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Histamine H1 Antagonists; Histamine H2 Antagonists; In Vitro Techniques; Indomethacin; Isoquinolines; Magnetic Resonance Spectroscopy; Male; Muscarinic Antagonists; Phenylephrine; Propranolol; Pyridines; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Yohimbine

2003
The quantitative evaluation of autonomic drugs on the isolated eye.
    The Journal of pharmacology and experimental therapeutics, 1962, Volume: 138

    Topics: Acetylcholine; Ammonium Compounds; Atropine; Autonomic Agents; Diphenhydramine; Epinephrine; Eye; Hexamethonium Compounds; Histamine; Humans; Isoflurophate; Isoproterenol; Mecamylamine; Methacholine Compounds; Miotics; Neostigmine; Norepinephrine; Parasympathomimetics; Phenylephrine; Physostigmine; Pilocarpine; Quaternary Ammonium Compounds

1962
[INDICATIONS, THERAPEUTIC EFFICACY AND TOLERANCE OF AN ANTIHISTAMINIC SYNERGISM (DIVAHISTINE)].
    Therapeutische Umschau. Revue therapeutique, 1963, Volume: 20

    Topics: Ascorbic Acid; Caffeine; Common Cold; Diphenhydramine; Humans; Immune Tolerance; Nasal Decongestants; Pheniramine; Phenylephrine; Rhinitis; Rhinitis, Allergic, Seasonal; Vasoconstrictor Agents

1963
The effect of morphine in rat small mesenteric arteries.
    Vascular pharmacology, 2005, Volume: 43, Issue:1

    Topics: Animals; Calcium; Diphenhydramine; Endothelium, Vascular; Enzyme Inhibitors; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Morphine; Muscle, Smooth, Vascular; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Vascular Resistance; Vasoconstrictor Agents

2005
Synchronous spectrofluorometric methods for simultaneous determination of diphenhydramine and ibuprofen or phenylephrine in combined pharmaceutical preparations.
    Luminescence : the journal of biological and chemical luminescence, 2020, Volume: 35, Issue:4

    Topics: Calibration; Diphenhydramine; Ibuprofen; Molecular Structure; Phenylephrine; Spectrometry, Fluorescence

2020
Chemometric assisted UV spectrophotometric and RP-HPLC methods for simultaneous determination of paracetamol, diphenhydramine, caffeine and phenylephrine in tablet dosage form.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2020, Dec-15, Volume: 243

    Topics: Acetaminophen; Caffeine; Chromatography, High Pressure Liquid; Diphenhydramine; Phenylephrine; Spectrophotometry, Ultraviolet; Tablets

2020
Pediatric Fatalities Associated With Over-the-Counter Cough and Cold Medications.
    Pediatrics, 2021, Volume: 148, Issue:5

    Topics: Antitussive Agents; Brompheniramine; Child; Child, Preschool; Chlorpheniramine; Dextromethorphan; Diphenhydramine; Doxylamine; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Female; Guaifenesin; Homicide; Humans; Infant; Male; Nonprescription Drugs; Phenylephrine; Pseudoephedrine

2021