diphenhydramine and paclitaxel

diphenhydramine has been researched along with paclitaxel in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.00)18.7374
1990's16 (32.00)18.2507
2000's24 (48.00)29.6817
2010's7 (14.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dutcher, JP; Lipton, RB; Paietta, E; Schwartz, EL; Strauman, JJ; Wiernik, PH1
Dutcher, JP; Einzig, A; Lipton, RB; Schwartz, EL; Strauman, JJ; Wiernik, PH1
Greco, FA; Hainsworth, JD2
Broder, S; Feigal, E; Feuerstein, I; Humphrey, RW; Lietzau, J; Odom, J; Pluda, JM; Saville, MW; Steinberg, SM; Wilson, WH1
Collins, JM; Jamis-Dow, CA; Katki, AG; Klecker, RW1
Barakat, R; Curtin, J; Francis, P; Hakes, T; Jones, W; Lewis, JL; Markman, M; Reichman, B; Rowinsky, E; Rubin, S1
Davilla, E; Dhingra, H; Fossella, FV; Gross, HM; Hynes, HE; Leimert, J; Murphy, WK; Raber, MN; Shin, DM; Winn, RJ1
Donehower, RC; Eisenhauer, EA; Gianni, L; Hubbard, JL; McGuire, WP; Onetto, N; Peereboom, DM; Piccart, M; Rowinsky, EK1
Cabanillas, F; Callendar, D; Hagemeister, F; Mansfield, P; McLaughlin, P; Mesina, O; Moore, D; North, L; Rodriguez, MA; Romaguera, J; Sarris, AH; Swan, F; Younes, A1
Balmaceda, C; Baselga, J; Bruno, R; Crown, JP; Currie, V; Freilich, R; Gilewski, TA; Gollub, M; Hakes, TB; Hudis, CA; Lebwohl, DE; Norton, L; Raptis, G; Robles, M; Seidman, AD1
Chan, AT; Johnson, PJ; Leung, WT; Yeo, W1
Ebbert, LP; Edmonson, JH; Gerstner, JB; Jung, SH; McGaw, H; Nascimento, AG1
Eisenhauer, E; Latreille, J; Paul, K; Shepherd, FA1
Bookman, MA; Kloth, DD; Kover, PE; Ozols, RF; Smolinski, S1
Miyata, Y; Nakanomyo, H; Nishiwaki, Y; Ohtsu, T; Saijo, N; Sasaki, Y; Tamura, T1
Jobe, DR; Kuhn, J; Rizzo, J; Schreeder, MT; Walton, GD1
Belinson, J; Kennedy, A; Kulp, B; Markman, M; Peterson, G; Webster, K2
Kearney, K; Myers, JS1
Bevers, M; Freedman, R; Kavanagh, JJ; Kudelka, AP; Moon, C; Verschraegen, CF1
Bando, H; Hayashi, K; Kuroi, K; Saji, S; Tanaka, C; Toi, M1
Elit, L; Finn, M; Hirte, H; Kwon, JS; Mazurka, J; Moens, F; Trim, K1
Hirano, M; Kikkawa, H; Kikuchi, T; Murakami, N; Nozawa, H; Okuda, T; Oya, J; Uno, Y1
Abbruzzese, JL; Evans, DB; Lenzi, R; Yalcin, S1
Dea, G; Gandara, D; Lara, P; Lau, D; Quock, J; Tanaka, M1
Emerich, J; Kobierski, J; Majdak, E; Mielcarek, P1
Inoue, K; Kai, T; Koh, J; Mihara, H; Mochizuki, H; Okubo, K; Saito, T; Sato, K; Tabei, T1
Fujii, T; Komatsu, M; Kumagai, M; Kusuda, T; Naitou, H; Shinkou, S; Takehara, K1
Doi, M; Egawa, T; Hayashi, S; Kitajima, M; Kitano, M; Kubota, T; Nagashima, A; Saikawa, Y; Yoshii, H1
Asmar, L; Dakhil, S; Friedland, DM; Gregurich, MA; Hollen, C1
Adamson, B; Braverman, AS; McManus, M; Pierre, S; Rao, S; Salvatti, ME1
Kobayashi, Y; Moritake, T; Nagashima, T; Ogura, H; Seiki, T; Terauchi, F; Yamamoto, Y1
Bander, R; Bukacel, DG; Ibrahim, RB1
Imai, S; Jitsuko, A; Nishikawa, H; Otoshi, M; Takahara, S; Tsubono, M; Wada, Y1
Furukawa, M; Hirashima, T; Kawase, I; Kobayashi, M; Matsui, K; Nakamura, Y; Nitta, T; Sasada, S; Takimoto, T1
Bafaloukos, D; Bakogiannis, C; Bamias, A; Boukovinas, I; Christodoulou, C; Dimopoulos, MA; Fountzilas, G; Kalofonos, HP; Kosmidis, PA; Makatsoris, T; Nicolaides, C; Samantas, E; Skarlos, D; Syrigos, K; Xiros, N1
Berger, MJ; Layman, R; Lustberg, MB; Macrae, E; Mrozek, E; Phillips, G; Ramaswamy, B; Shapiro, CL; Shaver, K; Vargo, C; Vincent, M; Wesolowski, R1
Castro, SN; de Castro Baccarin, AL; de Iracema Gomes Cubero, D; Del Giglio, A; Irene, MN; Luz, AS; Móz, LES; Sordi, R1
Durham, CG; Foster, J; Herrington, JD; Sager, L; Thotakura, D1
Beaucage-Charron, J; Bouchard, P; Charpentier, F; Gaudet, L; Lamothe, S; Lordkipanidzé, M; Pelletier, C; Pépin, AS; Picard, M; Projean, D; Roy, V1

Reviews

1 review(s) available for diphenhydramine and paclitaxel

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

21 trial(s) available for diphenhydramine and paclitaxel

ArticleYear
One-hour paclitaxel infusion schedules: a phase I/II comparative trial.
    Seminars in oncology, 1995, Volume: 22, Issue:3 Suppl 6

    Topics: Blood Cell Count; Breast Neoplasms; Cimetidine; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Neoplasms; Ovarian Neoplasms; Paclitaxel; Premedication; Remission Induction

1995
Treatment of HIV-associated Kaposi's sarcoma with paclitaxel.
    Lancet (London, England), 1995, Jul-01, Volume: 346, Issue:8966

    Topics: Acquired Immunodeficiency Syndrome; Adult; Cimetidine; Dexamethasone; Diphenhydramine; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Sarcoma, Kaposi

1995
Intraperitoneal Taxol (paclitaxel) in the management of ovarian cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 6

    Topics: Dexamethasone; Diphenhydramine; Drug Administration Schedule; Female; Humans; Injections, Intraperitoneal; Neutropenia; Ovarian Neoplasms; Paclitaxel; Premedication; Ranitidine; Treatment Outcome

1994
Paclitaxel administered by 1-hour infusion. Preliminary results of a phase I/II trial comparing two schedules.
    Cancer, 1994, Aug-15, Volume: 74, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cimetidine; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Hypersensitivity; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Paclitaxel; Premedication; Prospective Studies; Remission Induction

1994
Phase II study of taxol in patients with untreated advanced non-small-cell lung cancer.
    Journal of the National Cancer Institute, 1993, Mar-03, Volume: 85, Issue:5

    Topics: Carcinoma, Non-Small-Cell Lung; Cimetidine; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Humans; Lung Neoplasms; Neoplasm Staging; Paclitaxel; Premedication; Remission Induction

1993
Successful re-treatment with taxol after major hypersensitivity reactions.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:5

    Topics: Aged; Dexamethasone; Diphenhydramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Middle Aged; Paclitaxel; Premedication

1993
Cyclosporin A does not reverse clinical resistance to paclitaxel in patients with relapsed non-Hodgkin's lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Cross-Over Studies; Cyclosporine; Dexamethasone; Dextropropoxyphene; Diphenhydramine; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Infusions, Intravenous; Lymphoma, Non-Hodgkin; Male; Membrane Glycoproteins; Middle Aged; Neoplasm Proteins; Paclitaxel; Premedication; Recurrence; Remission Induction

1996
Phase II and pharmacologic study of docetaxel as initial chemotherapy for metastatic breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cimetidine; Dexamethasone; Diphenhydramine; Docetaxel; Drug Administration Schedule; Drug Hypersensitivity; Edema; Female; Humans; Injections, Intravenous; Leukopenia; Middle Aged; Neoplasm Metastasis; Paclitaxel; Premedication; Taxoids

1996
Phase II study of docetaxel in advanced soft tissue sarcomas.
    American journal of clinical oncology, 1996, Volume: 19, Issue:6

    Topics: Adult; Aged; Alopecia; Anorexia; Antiemetics; Antineoplastic Agents, Phytogenic; Cause of Death; Dexamethasone; Diarrhea; Diphenhydramine; Docetaxel; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Leiomyosarcoma; Leukopenia; Male; Middle Aged; Nausea; Paclitaxel; Patient Selection; Premedication; Remission Induction; Sarcoma; Taxoids; Uterine Neoplasms; Vomiting

1996
Phase I dose-escalation trial of paclitaxel and ifosfamide in patients with advanced non-small cell lung cancer.
    Seminars in oncology, 1996, Volume: 23, Issue:6 Suppl 16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Arthralgia; Carcinoma, Non-Small-Cell Lung; Confusion; Dexamethasone; Diphenhydramine; Drug Tolerance; Female; Hematuria; Humans; Ifosfamide; Infusions, Parenteral; Lung Neoplasms; Male; Middle Aged; Muscular Diseases; Neutropenia; Paclitaxel; Paresthesia; Survival Rate; Treatment Outcome

1996
Short-course intravenous prophylaxis for paclitaxel-related hypersensitivity reactions.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Hypersensitivity; Female; Glucocorticoids; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Paclitaxel; Ranitidine; Retrospective Studies

1997
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Relationship, Drug; Drug Hypersensitivity; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Infusions, Intravenous; Leukocyte Count; Neoplasms; Paclitaxel; Ranitidine; Time Factors

1995
Paclitaxel-associated hypersensitivity reactions: experience of the gynecologic oncology program of the Cleveland Clinic Cancer Center.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Clinical Protocols; Desensitization, Immunologic; Dexamethasone; Diphenhydramine; Drug Hypersensitivity; Drug Therapy, Combination; Famotidine; Female; Genital Neoplasms, Female; Glucocorticoids; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Middle Aged; Paclitaxel; Premedication

2000
[Weekly administration of low-dose paclitaxel for advanced or metastatic breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:2

    Topics: Aged; Alopecia; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Middle Aged; Nausea; Neoplasm Recurrence, Local; Paclitaxel; Ranitidine; Vomiting, Anticipatory

2002
Phase II study of docetaxel in patients with pancreatic cancer previously untreated with cytotoxic chemotherapy.
    Cancer investigation, 2002, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Docetaxel; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Male; Maximum Tolerated Dose; Middle Aged; Paclitaxel; Pancreatic Neoplasms; Survival Rate; Taxoids; Treatment Outcome

2002
Multicenter phase II trial of weekly paclitaxel for advanced or metastatic breast cancer: the Saitama Breast Cancer Clinical Study Group (SBCCSG-01).
    Japanese journal of clinical oncology, 2003, Volume: 33, Issue:8

    Topics: Adult; Aged; Alopecia; Antiemetics; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Feasibility Studies; Female; Humans; Infusions, Intravenous; Lung Neoplasms; Middle Aged; Neutropenia; Paclitaxel; Ranitidine; Soft Tissue Neoplasms; Vomiting, Anticipatory

2003
A phase II evaluation of weekly paclitaxel plus carboplatin in advanced urothelial cancer.
    Cancer investigation, 2004, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Carboplatin; Carcinoma; Combined Modality Therapy; Dexamethasone; Diphenhydramine; Disease-Free Survival; Drug Administration Schedule; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Hyperglycemia; Life Tables; Male; Middle Aged; Neoplasm Staging; Paclitaxel; Peripheral Nervous System Diseases; Premedication; Survival Analysis; Treatment Outcome; Urologic Neoplasms; Urothelium

2004
[A phase II study of weekly paclitaxel for advanced or recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:7

    Topics: Adult; Aged; Alopecia; Antiemetics; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Breast Neoplasms; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Female; Humans; Leukopenia; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Ranitidine; Survival Rate

2007
Paclitaxel and gemcitabine versus carboplatin and gemcitabine in patients with advanced non-small-cell lung cancer. A phase III study of the Hellenic Cooperative Oncology Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Chemical and Drug Induced Liver Injury; Cimetidine; Deoxycytidine; Dexamethasone; Diphenhydramine; Female; Gemcitabine; Heart Diseases; Hematologic Diseases; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Ondansetron; Paclitaxel; Premedication; Proportional Hazards Models

2008
The feasibility of dexamethasone omission in weekly paclitaxel treatment for breast cancer patients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Hypersensitivity; Drug Substitution; Feasibility Studies; Female; Humans; Incidence; Infusions, Intravenous; Middle Aged; Paclitaxel; Premedication; Prospective Studies; Quality of Life

2019
A randomized double-blind feasibility study comparing cetirizine and diphenhydramine in the prevention of paclitaxel-associated infusion-related reactions: the PREMED-F1 study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:4

    Topics: Cetirizine; Diphenhydramine; Double-Blind Method; Feasibility Studies; Humans; Paclitaxel; Premedication; Prospective Studies

2022

Other Studies

28 other study(ies) available for diphenhydramine and paclitaxel

ArticleYear
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Phase I clinical and pharmacokinetic study of taxol.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alkaloids; Alopecia; Cimetidine; Dexamethasone; Diphenhydramine; Drug Evaluation; Drug Interactions; Female; Half-Life; Humans; Kinetics; Leukopenia; Male; Middle Aged; Nausea; Neoplasms; Nervous System; Ovarian Neoplasms; Paclitaxel; Premedication; Stomach Neoplasms; Vomiting

1987
Phase I trial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Evaluation; Drug Hypersensitivity; Humans; Infusions, Intravenous; Kinetics; Melanoma; Neoplasms; Nervous System Diseases; Neutropenia; Paclitaxel

1987
Metabolism of taxol by human and rat liver in vitro: a screen for drug interactions and interspecies differences.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:2

    Topics: Animals; Biotransformation; Cimetidine; Cytochrome P-450 Enzyme System; Dexamethasone; Diphenhydramine; Drug Evaluation, Preclinical; Drug Interactions; Glycerol; Humans; In Vitro Techniques; Ketoconazole; Kinetics; Liver; Microsomes, Liver; Paclitaxel; Quinidine; Rats; Species Specificity; Surface-Active Agents; Taxoids; Tritium

1995
Thromboembolic events with paclitaxel.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1996, Volume: 8, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cerebral Infarction; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Intracranial Embolism and Thrombosis; Ovarian Neoplasms; Paclitaxel; Premedication; Seizures

1996
Hepatic artery administration of paclitaxel.
    Cancer investigation, 1999, Volume: 17, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Small Cell; Cimetidine; Combined Modality Therapy; Dexamethasone; Diphenhydramine; Etoposide; Hepatic Artery; Humans; Injections, Intra-Arterial; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Premedication

1999
An effective and more convenient drug regimen for prophylaxis against paclitaxel-associated hypersensitivity reactions.
    Journal of cancer research and clinical oncology, 1999, Volume: 125, Issue:7

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Hypersensitivity; Famotidine; Female; Genital Neoplasms, Female; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Injections, Intravenous; Paclitaxel; Treatment Outcome

1999
Emergency. Chemotherapy-induced hypersensitivity reaction.
    The American journal of nursing, 2000, Volume: 100, Issue:4

    Topics: Anti-Allergic Agents; Antineoplastic Agents, Phytogenic; Diphenhydramine; Drug Hypersensitivity; Emergencies; Female; Humans; Methylprednisolone; Middle Aged; Ovarian Neoplasms; Paclitaxel

2000
Use of docetaxel (Taxotere) in patients with paclitaxel (Taxol) hypersensitivity.
    Anti-cancer drugs, 2000, Volume: 11, Issue:7

    Topics: Adult; Antineoplastic Agents, Phytogenic; Carcinoma; Cimetidine; Cystadenocarcinoma; Dexamethasone; Diphenhydramine; Docetaxel; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Middle Aged; Ovarian Neoplasms; Paclitaxel; Taxoids

2000
[Efficacy of biweekly paclitaxel therapy in advanced or recurrent breast cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:1

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Feasibility Studies; Female; Histamine H2 Antagonists; Humans; Middle Aged; Neoplasm Metastasis; Paclitaxel; Pilot Projects; Ranitidine

2002
A comparison of two prophylactic regimens for hypersensitivity reactions to paclitaxel.
    Gynecologic oncology, 2002, Volume: 84, Issue:3

    Topics: Administration, Oral; Cohort Studies; Dexamethasone; Diphenhydramine; Drug Hypersensitivity; Female; Glucocorticoids; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Injections, Intravenous; Ovarian Neoplasms; Paclitaxel; Peritoneal Neoplasms; Ranitidine; Retrospective Studies

2002
Premedication strategy for weekly paclitaxel.
    Cancer investigation, 2002, Volume: 20, Issue:5-6

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Infusions, Intravenous; Male; Middle Aged; Paclitaxel; Retrospective Studies

2002
[Paclitaxel hypersensitivity reactions in patients with advanced ovarian carcinoma].
    Ginekologia polska, 2002, Volume: 73, Issue:11

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Female; Glucocorticoids; Histamine H1 Antagonists; Humans; Middle Aged; Ovarian Neoplasms; Paclitaxel; Radiation-Sensitizing Agents; Retrospective Studies; Severity of Illness Index

2002
[Paclitaxel plus carboplatin in ovarian cancer-comparison of adverse effects between monthly and weekly administration].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:4

    Topics: Adult; Aged; Anorexia; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dexamethasone; Diarrhea; Diphenhydramine; Drug Administration Schedule; Female; Humans; Leukopenia; Middle Aged; Nausea; Ovarian Neoplasms; Paclitaxel; Ranitidine; Retrospective Studies; Thrombocytopenia

2004
[Usefulness of weekly administration of paclitaxel for advanced or recurrent gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:6

    Topics: Adult; Aged; Antiemetics; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Feasibility Studies; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Ranitidine; Stomach Neoplasms; Survival Analysis

2004
Tapering and discontinuation of glucocorticoid prophylaxis during prolonged weekly to biweekly paclitaxel administration.
    Chemotherapy, 2005, Volume: 51, Issue:2-3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Middle Aged; Paclitaxel; Prospective Studies

2005
A pilot study of weekly paclitaxel administration for patients with relapsed cervical cancer after heavy medication.
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:5

    Topics: Agranulocytosis; Alopecia; Antiemetics; Antineoplastic Agents, Phytogenic; Cimetidine; Combined Modality Therapy; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hysterectomy; Infusions, Intravenous; Lymph Node Excision; Neoplasm Recurrence, Local; Paclitaxel; Pilot Projects; Survival Rate; Uterine Cervical Neoplasms

2005
Cross-reactivity between paclitaxel and hazelnut: a case report.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2007, Volume: 13, Issue:1

    Topics: Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Corylus; Cross Reactions; Diphenhydramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Humans; Hydrocortisone; Hypersensitivity, Immediate; Nut Hypersensitivity; Paclitaxel; Plant Proteins; Urinary Bladder Neoplasms

2007
Preliminary experience with a modified premedication protocol that included intravenous diphenhydramine and calcium bromide for the prophylaxis of paclitaxel-related hypersensitivity reactions.
    International journal of clinical oncology, 2007, Volume: 12, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Bromides; Calcium Compounds; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Diphenhydramine; Drug Hypersensitivity; Female; Humans; Injections, Intravenous; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Premedication; Retrospective Studies

2007
Stopping paclitaxel premedication after two doses in patients not experiencing a previous infusion hypersensitivity reaction.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Dexamethasone; Diphenhydramine; Drug Administration Schedule; Drug Hypersensitivity; Famotidine; Female; Humans; Infusions, Intravenous; Middle Aged; Neoplasm Staging; Paclitaxel; Premedication; Prospective Studies; Retrospective Studies

2015
Cetirizine versus diphenhydramine in the prevention of chemotherapy-related hypersensitivity reactions.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:6

    Topics: Aged; Antineoplastic Agents, Immunological; Antineoplastic Agents, Phytogenic; Cetirizine; Cetuximab; Diphenhydramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Infusions, Intravenous; Male; Middle Aged; Paclitaxel; Premedication; Prospective Studies; Retrospective Studies; Rituximab

2019