diphenhydramine and oxycodone

diphenhydramine has been researched along with oxycodone in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (13.33)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (46.67)	29.6817
2010's	6 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S	1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
de Haen, P	1
Mattila, MJ; Saarialho-Kere, U; Seppälä, T	1
Goklaney, A; Halcomb, SE; Mullins, ME; Sivilotti, ML	1
Abazia, DT; Marcus, A; Ross, J; Sachinwalla, E; Smolarz, BG	1
Björkman, S; Borgs, A; Deguchi, Y; Hammarlund-Udenaes, M; Jansson, B; Kato, S; Okura, T; Sadiq, MW; Shimomura, K; Terasaki, T	1
Doran, AC; Mancuso, JY; Osgood, SM; Shaffer, CL	1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M	1

Reviews

2 review(s) available for diphenhydramine and oxycodone

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for diphenhydramine and oxycodone

Article	Year
Psychomotor, respiratory and neuroendocrinological effects of a mu-opioid receptor agonist (oxycodone) in healthy volunteers. Pharmacology & toxicology, 1989, Volume: 65, Issue:4 Topics: Adult; Codeine; Diphenhydramine; Female; Flicker Fusion; Growth Hormone; Humans; Male; Neurosecretory Systems; Oxycodone; Prolactin; Psychomotor Performance; Receptors, Opioid; Receptors, Opioid, mu; Respiration	1989
Pharmacokinetic effects of diphenhydramine or oxycodone in simulated acetaminophen overdose. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:2 Topics: Absorption; Acetaminophen; Analysis of Variance; Area Under Curve; Cross-Over Studies; Diphenhydramine; Drug Overdose; Female; Humans; Male; Oxycodone; Prospective Studies; Statistics, Nonparametric	2005

Article

Year

Psychomotor, respiratory and neuroendocrinological effects of a mu-opioid receptor agonist (oxycodone) in healthy volunteers.

Pharmacology & toxicology, 1989, Volume: 65, Issue:4

Topics: Adult; Codeine; Diphenhydramine; Female; Flicker Fusion; Growth Hormone; Humans; Male; Neurosecretory Systems; Oxycodone; Prolactin; Psychomotor Performance; Receptors, Opioid; Receptors, Opioid, mu; Respiration

1989

Pharmacokinetic effects of diphenhydramine or oxycodone in simulated acetaminophen overdose.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:2

Topics: Absorption; Acetaminophen; Analysis of Variance; Area Under Curve; Cross-Over Studies; Diphenhydramine; Drug Overdose; Female; Humans; Male; Oxycodone; Prospective Studies; Statistics, Nonparametric

2005

Other Studies

11 other study(ies) available for diphenhydramine and oxycodone

Article	Year
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids. Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20 Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley	2009
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution	2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Drugs released for clinical use. Journal of clinical pharmacology, 1978, Volume: 18, Issue:1 Topics: Analgesics; Anti-Inflammatory Agents; Antitussive Agents; Betamethasone; Cimetidine; Colestipol; Dihydroergotoxine; Diphenhydramine; Drug Therapy; Furosemide; Humans; Isosorbide; Oxycodone; Pharmaceutical Preparations; Salicylates; United States; United States Food and Drug Administration; Vitamins	1978
Noncardiogenic pulmonary edema in a patient receiving vancomycin and oxycodone-acetaminophen. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2008, Volume: 100, Issue:6 Topics: Acetamides; Acetaminophen; Analgesics; Anti-Infective Agents; Cellulitis; Diphenhydramine; Drug Combinations; Famotidine; Furosemide; Humans; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Oxycodone; Pulmonary Edema; Staphylococcal Skin Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin	2008
Diphenhydramine active uptake at the blood-brain barrier and its interaction with oxycodone in vitro and in vivo. Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:9 Topics: Animals; Blood-Brain Barrier; Cell Line, Transformed; Chromatography, Liquid; Diphenhydramine; Drug Interactions; Endothelium, Vascular; Histamine H1 Antagonists; In Vitro Techniques; Male; Mass Spectrometry; Oxycodone; Quality Control; Rats; Rats, Sprague-Dawley; Reference Standards	2011
Diphenhydramine has similar interspecies net active influx at the blood-brain barrier. Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:5 Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Diphenhydramine; Dogs; Extracellular Fluid; Female; Macaca fascicularis; Male; Microdialysis; Oxycodone; Rats; Rats, Sprague-Dawley	2014
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology. Journal of analytical toxicology, 2014, Volume: 38, Issue:8 Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry	2014