diphenhydramine has been researched along with orphenadrine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (78.79) | 18.7374 |
| 1990's | 1 (3.03) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Sen, S; Sinha, N | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Donnell, D; Glaser, R; Maartmann-Moe, K | 1 |
| Caddy, B; Fish, F; Mullen, PW; Tranter, J | 1 |
| Heikkila, RE; Orlansky, H | 1 |
| Bilzer, W; Gundert-Remy, U | 1 |
| Draper, MD; Ginzel, KH; Klohs, MW; Petracek, FJ; Ré, ON | 1 |
| Ban, T; Hojo, M | 1 |
| Florio, V; Longo, VG | 1 |
| Ginzel, KH | 1 |
| Heus, WJ; Nauta, WT; van der Stelt, C | 1 |
| de Roos, AM; Doorenbos, HJ; Nauta, WT | 1 |
| Hoffman, BF | 1 |
| Gielsdorf, W; Jaeger, H; Lutz, D | 1 |
| Guay, DR; Meatherall, RC | 1 |
| KOSTER, S | 1 |
| CONSTABLE, K; DOSHAY, LJ | 1 |
| PULVER, SE; ROBITSCHER, JB | 1 |
| HAVINGA, H | 1 |
| KRONEBERG, G | 1 |
| MASCIOCCHI, A; SFRONDINI, E | 1 |
| GOLDNER, MG; NAYAMPALLI, SS; ROSENFELD, S | 1 |
| EVRARD, A | 1 |
| GOLDSTEIN, L; JENNEY, EH; MURPHREE, HB; PFEIFFER, CC | 1 |
| DRAPER, IT; JOHNS, RJ | 1 |
| HERZ, A; HOFSTETTER, A; KURZ, H; TESCHEMACHER, H | 1 |
| ERNSTING, W | 1 |
1 review(s) available for diphenhydramine and orphenadrine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
32 other study(ies) available for diphenhydramine and orphenadrine
| Article | Year |
|---|---|
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Solid-state structure of orphenadrine hydrochloride and conformational comparisons with diphenhydramine hydrochloride and nefopam hydrochloride.
Topics: Diphenhydramine; Magnetic Resonance Spectroscopy; Molecular Conformation; Nefopam; Orphenadrine; X-Ray Diffraction | 1992 |
An oxidative analytical procedure for some compounds containing the diphenylmethylidene group.
Topics: Benzene Derivatives; Chromatography; Cyclizine; Diphenhydramine; Methadone; Methods; Orphenadrine; Oxidation-Reduction; Piperazines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1973 |
An evaluation of various antiparkinsonian agents as releasing agents and uptake inhibitors for 3H-dopamine in slices of rat neostriatum.
Topics: Animals; Antiparkinson Agents; Benztropine; Catecholamines; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Diphenhydramine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Orphenadrine; Putamen; Rats; Serotonin; Trihexyphenidyl; Tritium | 1974 |
Determination of nanogram quantities of diphenhydramine and orphenadrine in human plasma using gas-liquid chromatography.
Topics: Chromatography, Gas; Diphenhydramine; Dose-Response Relationship, Drug; Humans; Male; Methods; Orphenadrine; Time Factors | 1973 |
Benzoxazocines: a new chemical class of centrally acting skeletal muscle relaxants.
Topics: Azocines; Benzene Derivatives; Diphenhydramine; Muscle Relaxants, Central; Orphenadrine; Structure-Activity Relationship | 1972 |
A comparative study of the effects of anti-parkinson drugs on the oxotremorine-induced EEG and muscular activities.
Topics: Animals; Diphenhydramine; Drug Antagonism; Electroencephalography; Male; Muscle Tonus; Muscles; Orphenadrine; Parasympatholytics; Parkinson Disease; Propantheline; Propranolol; Pyrrolidinones; Rabbits; Scopolamine; Spasm; Tremorine; Trihexyphenidyl | 1971 |
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice.
Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl | 1971 |
The blockade of reticular and spinal facilitation of motor function by orphenadrine.
Topics: Animals; Cats; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cordotomy; Decerebrate State; Diphenhydramine; Electric Stimulation; Mephenesin; Orphenadrine; Reflex, Stretch; Reticular Formation; Sciatic Nerve; Scopolamine; Spinal Cord | 1966 |
The resolution in optical isomers of orphenadrine, 4-methyldiphenhydramine and their N-demethyl derivatives.
Topics: Chemistry, Pharmaceutical; Diphenhydramine; Optical Rotatory Dispersion; Orphenadrine; Oxidation-Reduction; Receptors, Drug; Stereoisomerism | 1969 |
Investigation of 4-methyldiphenhydramine hydrochloride, N,N-dimethyl-2-[(p-methyl-alpha-phenylbenzyl)oxy]ethylamine hydrochloride.
Topics: Chromatography; Diphenhydramine; Orphenadrine; Potentiometry; Spectrophotometry | 1967 |
Antiparkinsonism drugs.
Topics: Antidepressive Agents; Atropine; Diphenhydramine; Humans; Orphenadrine; Parasympatholytics; Parkinson Disease; Promethazine; Scopolamine; Trihexyphenidyl | 1965 |
The diagnosis and treatment of neuroleptic-induced Parkinsonism.
Topics: Antipsychotic Agents; Depression; Diagnosis, Differential; Diphenhydramine; Humans; Neurologic Examination; Orphenadrine; Parkinson Disease, Secondary; Patient Compliance | 1981 |
Quantitative determination of diphenhydramine and orphenadrine in human serum by capillary gas chromatography.
Topics: Chromatography, Gas; Diphenhydramine; Humans; Kinetics; Orphenadrine | 1983 |
Isothermal gas chromatographic analysis of diphenhydramine after direct injection onto a fused-silica capillary column.
Topics: Caffeine; Chromatography, Gas; Diphenhydramine; Humans; Orphenadrine; Time Factors | 1984 |
[Experience with disipal (BS 5930) in paralysis agitans].
Topics: Diphenhydramine; Orphenadrine; Parkinson Disease | 1955 |
Treatment of paralysis agitans with orphenadrine (disipal) hydrochloride; results in one hundred seventy-six cases.
Topics: Diphenhydramine; Orphenadrine; Parkinson Disease; Salts | 1957 |
Orphenadrine in the treatment of depression; a preliminary study.
Topics: Depression; Depressive Disorder; Diphenhydramine; Orphenadrine | 1958 |
ORPHENADRINE hydrochloride.
Topics: Diphenhydramine; Orphenadrine | 1958 |
[Treatment of posttraumatic dizziness with disipal].
Topics: Craniocerebral Trauma; Diphenhydramine; Dizziness; Humans; Orphenadrine; Vertigo | 1958 |
[Pharmacological bases of the reserpine-mephenamine combination (phasein)].
Topics: Diphenhydramine; Orphenadrine; Reserpine | 1958 |
[Disipal in the treatment of post-encephalitic parkinsonism].
Topics: Diphenhydramine; Encephalitis; Humans; Orphenadrine; Parkinson Disease; Parkinson Disease, Postencephalitic | 1958 |
An evaluation of orphenadrine hydrochloride (disipal).
Topics: Aged; Diphenhydramine; Humans; Orphenadrine; Parkinson Disease | 1959 |
[Use of orphenadrine in neurology & psychiatry].
Topics: Diphenhydramine; Humans; Mental Disorders; Nervous System Diseases; Neurology; Orphenadrine; Psychiatry; Psychotherapy | 1959 |
ELECTROENCEPHALOGRAPHIC ASSAY OF ANTI-ANXIETY DRUGS.
Topics: Adolescent; Anti-Anxiety Agents; Atropine; Chlordiazepoxide; Diphenhydramine; Electroencephalography; Meprobamate; Orphenadrine; Pharmacology; Placebos | 1964 |
THE DISORDERED MOVEMENT IN PARKINSONISM AND THE EFFECT OF DRUG TREATMENT.
Topics: Atropine; Dextroamphetamine; Diphenhydramine; Drug Therapy; Geriatrics; Humans; Kinetics; Motor Skills; Movement Disorders; Orphenadrine; Parasympatholytics; Parkinsonian Disorders; Reaction Time; Trihexyphenidyl | 1964 |
THE IMPORTANCE OF LIPID-SOLUBILITY FOR THE CENTRAL ACTION OF CHOLINOLYTIC DRUGS.
Topics: Atropine; Benactyzine; Blood-Brain Barrier; Brain; Cholinergic Antagonists; Diphenhydramine; Electroencephalography; Lipids; Mice; Morphine; Orphenadrine; Parasympatholytics; Parasympathomimetics; Pharmacology; Pupil; Rabbits; Rats; Research; Scopolamine; Solubility | 1965 |
[The treatment of the Parkinson syndrome with disipal (BS 5930)].
Topics: Diphenhydramine; Orphenadrine; Parkinson Disease | 1955 |