diphenhydramine and nitrazepam

diphenhydramine has been researched along with nitrazepam in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Rooke, KC1
Baiotti, G1
Harvey, P; Mitchard, M; Roden, S1
Browning, M; Crooks, J; O'Malley, K; Stevenson, IH1
Hirase, M; Kamei, C; Shinomiya, K; Takeda, Y; Tokunaga, S1

Trials

2 trial(s) available for diphenhydramine and nitrazepam

ArticleYear
Comparative trial of a new hypnotic (Finorgal) with nitrazepam and triclofos sodium.
    The Journal of international medical research, 1979, Volume: 7, Issue:5

    Topics: Administration, Oral; Adult; Aged; Capsules; Clinical Trials as Topic; Diphenhydramine; Double-Blind Method; Drug Combinations; Ethchlorvynol; Ethylene Chlorohydrin; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Nitrazepam; Organophosphorus Compounds; Sleep Initiation and Maintenance Disorders

1979
The influence of alcohol on the persistent effects on human performance of the hypnotics Mandrax and Nitrazepam.
    International journal of clinical pharmacology and biopharmacy, 1977, Volume: 15, Issue:8

    Topics: Adult; Diphenhydramine; Double-Blind Method; Drug Combinations; Drug Interactions; Emotions; Ethanol; Female; Humans; Male; Methaqualone; Nitrazepam; Placebos; Task Performance and Analysis; Time Factors; Visual Acuity

1977

Other Studies

9 other study(ies) available for diphenhydramine and nitrazepam

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
The use of flurazepam (dalmane) as a substitute for barbiturates and methaqualone/diphenhydramine (mandrax) in general practice.
    The Journal of international medical research, 1976, Volume: 4, Issue:5

    Topics: Adult; Aged; Anti-Anxiety Agents; Barbiturates; Diphenhydramine; Drug Combinations; Family Practice; Female; Flurazepam; Humans; Male; Methaqualone; Middle Aged; Nitrazepam; Sleep Initiation and Maintenance Disorders

1976
Changes in human drug metabolism after long-term exposure to hypnotics.
    British medical journal, 1972, Nov-11, Volume: 4, Issue:5836

    Topics: Adolescent; Adult; Amobarbital; Antipyrine; Diphenhydramine; Drug Interactions; Humans; Hydrocortisone; Hypnotics and Sedatives; Methaqualone; Middle Aged; Nitrazepam; Phenylbutazone; Time Factors

1972
Effects of some H1-antagonists on the sleep-wake cycle in sleep-disturbed rats.
    Journal of pharmacological sciences, 2007, Volume: 103, Issue:2

    Topics: Animals; Chlorpheniramine; Cyproheptadine; Diphenhydramine; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Histamine H1 Antagonists; Hypnotics and Sedatives; Male; Nitrazepam; Rats; Sleep; Sleep Wake Disorders; Sleep, REM; Wakefulness

2007