diphenhydramine and naloxone

diphenhydramine has been researched along with naloxone in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (44.44)	18.7374
1990's	2 (5.56)	18.2507
2000's	10 (27.78)	29.6817
2010's	7 (19.44)	24.3611
2020's	1 (2.78)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Gozalbes, R; Pineda-Lucena, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brown, M; Rivier, C; Vale, W	1
Rivier, C; Vale, W	1
Abe, H; Imura, H; Iwasaki, J; Iwasaki, Y; Kato, Y; Yanaihara, N	1
Muraki, T; Tokunaga, Y	1
Ehrenpreis, S; Kimura, I; Kimura, M; Kobayashi, T	1
Hikasa, Y; Ogasawara, S; Takase, K	1
Carr, KD; Hiller, JM; Simon, EJ	1
Hoshi, T; Kitazawa, T; Kondo, H; Temma, K	1
Betti, R; Casanueva, FF; Cella, SG; Müller, EE	1
Bell, S; Jhamandas, K; Sutak, M	1
Foldes, FF	1
Carlson, HE; Levin, ER; Sharp, B	1
Chung, YH; Kamei, C; Miyake, H; Tasaka, K	1
Dowling, DA; Moore, RH	2
Ganes, EM; Jenkins, JT; Lind, RE; Reynolds, DG	1
Bocheva, A; Georgieva, M; Golovinsky, E; Pajpanova, T; Todorov, S; Zamfirova, R	1
Brown, DR; Poonyachoti, S	1
Rao, VS; Santos, FA	1
Armstrong, C; Baber, SR; Baluch, A; Fields, A; Hoover, JM; Huffman, S; Ibrahim, IN; Kaye, AD; Phelps, J; Zhang, C	1
Bocheva, A; Dobrinova, Y; Todorov, S; Zamfirova, R	1
Anwar, M; Bajwa, A; Baluch, A; Chilian, W; Fields, AM; Fox, C; Hoover, JM; Huffman, S; Ibrahim, IN; Kaye, AD; Kaye, AJ	1
Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW	1
Corrêa Benedet Baesso, K; De Sá Soares, A; Schuelter-Trevisol, F; Zapelini do Nascimento, D	1

Reviews

3 review(s) available for diphenhydramine and naloxone

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Neuroleptanalgesia for awake intubation and peroral endoscopies. International anesthesiology clinics, 1973,Fall, Volume: 11, Issue:3 Topics: Anesthesia, Local; Atropine; Blood Pressure; Bronchoscopy; Diphenhydramine; Droperidol; Endoscopy; Esophagoscopy; Fentanyl; Gastric Lavage; Gastroscopy; Glucose; Humans; Inhalation; Intubation, Gastrointestinal; Meperidine; Naloxone; Neuroleptanalgesia; Pentobarbital; Preanesthetic Medication; Pulse; Respiration; Scopolamine; Tetracaine	1973

Trials

1 trial(s) available for diphenhydramine and naloxone

Article	Year
Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:6 Topics: Adult; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Ondansetron; Pain, Postoperative; Patient Satisfaction; Postoperative Nausea and Vomiting; Pregnancy; Pruritus; Recurrence; Serotonin Antagonists; Severity of Illness Index	2010

Article

Year

Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery.

Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:6

Topics: Adult; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Ondansetron; Pain, Postoperative; Patient Satisfaction; Postoperative Nausea and Vomiting; Pregnancy; Pruritus; Recurrence; Serotonin Antagonists; Severity of Illness Index

2010

Other Studies

32 other study(ies) available for diphenhydramine and naloxone

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Effect of neurotensin, substance P and morphine sulfate on the secretion of prolactin and growth hormone in the rat. Endocrinology, 1977, Volume: 100, Issue:3 Topics: Animals; Diphenhydramine; Estrogens; Growth Hormone; Male; Morphine; Naloxone; Neurotensin; Progesterone; Prolactin; Rats; Secretory Rate; Substance P; Thyrotropin-Releasing Hormone	1977
Effects of gamma-aminobutyric acid and histamine on prolactin secretion in the rat. Endocrinology, 1977, Volume: 101, Issue:2 Topics: Aminobutyrates; Animals; Bicuculline; Cells, Cultured; Clonidine; Diphenhydramine; Dopamine; Drug Interactions; Estrogens; gamma-Aminobutyric Acid; Haloperidol; Histamine; Male; Morphine; Naloxone; Nerve Tissue Proteins; Phenoxybenzamine; Pituitary Gland; Progesterone; Prolactin; Rats; Thyrotropin-Releasing Hormone	1977
Prolactin release by vasoactive intestinal polypeptide in rats. Endocrinology, 1978, Volume: 103, Issue:2 Topics: Animals; Cyproheptadine; Diphenhydramine; Dopamine; Gastrointestinal Hormones; Kinetics; Male; Naloxone; Pilocarpine; Pituitary Gland, Anterior; Prolactin; Rats; Vasoactive Intestinal Peptide	1978
Effects of morphine on the serum prolactin levels of morphine-tolerant and nontolerant male rats and of the in vitro release of pituitary prolactin. Japanese journal of pharmacology, 1978, Volume: 28, Issue:6 Topics: Animals; Apomorphine; Diphenhydramine; Dopamine; Drug Tolerance; Haloperidol; In Vitro Techniques; Male; Morphine; Naloxone; Pituitary Gland, Anterior; Prolactin; Rats	1978
Histamine release as the basis for morphine action on bile duct and sphincter of Oddi. Life sciences, 1987, Apr-27, Volume: 40, Issue:17 Topics: Animals; Bile Ducts; Burimamide; Diphenhydramine; Histamine Release; In Vitro Techniques; Male; Morphine; Naloxone; p-Methoxy-N-methylphenethylamine; Sphincter of Oddi; Swine	1987
Evidence for the involvement of alpha 2-adrenoceptors in the emetic action of xylazine in cats. American journal of veterinary research, 1989, Volume: 50, Issue:8 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Cat Diseases; Cats; Chlorpromazine; Diphenhydramine; Domperidone; Female; Hydroxydopamines; Male; Naloxone; Oxidopamine; Propranolol; Random Allocation; Receptors, Adrenergic, alpha; Thiazines; Vomiting; Xylazine	1989
Diphenhydramine potentiates narcotic but not endogenous opioid analgesia. Neuropeptides, 1985, Volume: 5, Issue:4-6 Topics: Analgesics; Analgesics, Opioid; Animals; Diphenhydramine; Drug Interactions; Drug Synergism; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid	1985
Effects of morphine and methionine-enkephalin on the smooth muscle tonus and the contraction induced by transmural stimulation in the carp (Cyprinus carpio) intestinal bulb. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1986, Volume: 84, Issue:2 Topics: Acetylcholine; Animals; Atropine; Carps; Diphenhydramine; Electric Stimulation; Enkephalin, Methionine; Female; Hexamethonium; Hexamethonium Compounds; Intestines; Isometric Contraction; Male; Morphine; Muscle Contraction; Muscle Tonus; Naloxone; Tetrodotoxin	1986
Activation of the cholinergic system and growth hormone release in the dog: functional interactions with other neurotransmitters. Acta endocrinologica, 1985, Volume: 108, Issue:1 Topics: Animals; Behavior, Animal; Cimetidine; Clemastine; Diphenhydramine; Dogs; Domperidone; Female; Fenfluramine; Growth Hormone; Male; Metergoline; Naloxone; Phentolamine; Physostigmine; Pimozide; Pizotyline; Propranolol; Radioimmunoassay; Receptors, Cholinergic; Synaptic Transmission	1985
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms. European journal of pharmacology, 1973, Volume: 24, Issue:3 Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline	1973
Studies of naloxone-induced secretion of beta-endorphin immunoreactivity in dogs. Life sciences, 1984, Oct-08, Volume: 35, Issue:15 Topics: Animals; Atropine; beta-Endorphin; Dexamethasone; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Endorphins; Metergoline; Naloxone; Neurotransmitter Agents; Phentolamine; Radioimmunoassay	1984
Analgesic effect of histamine induced by intracerebral injection into mice. Agents and actions, 1984, Volume: 15, Issue:3-4 Topics: Analgesics; Animals; Benzoquinones; Cimetidine; Diphenhydramine; Electric Stimulation; Enkephalin, Leucine; Histamine; Histamine Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Promethazine; Pyrilamine; Quinones; Reaction Time	1984
Effects of enkephalins on perfusion pressure in isolated hindlimb preparations. Life sciences, 1982, Oct-11, Volume: 31, Issue:15 Topics: Animals; Blood Pressure; Cats; Diphenhydramine; Dose-Response Relationship, Drug; Drug Antagonism; Enkephalin, Leucine; Enkephalin, Methionine; Female; Femoral Artery; In Vitro Techniques; Injections, Intra-Arterial; Male; Naloxone; Perfusion; Propranolol; Vasodilation	1982
Morphine effects on cardiovascular performance. The American surgeon, 1981, Volume: 47, Issue:3 Topics: Animals; Autonomic Nervous System; Cardiovascular System; Cimetidine; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Heart; Hemodynamics; Morphine; Naloxone	1981
Effects of intravenously administered Leu- or Met-enkephalin on arterial blood pressure. Regulatory peptides, 1980, Volume: 1, Issue:2 Topics: Animals; Blood Pressure; Cats; Diphenhydramine; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Female; Injections, Intravenous; Male; Naloxone; Propranolol	1980
Effect of diphenylhydramine on the Tyr-MIF-1 antinociception in rats. Archives of physiology and biochemistry, 1998, Volume: 106, Issue:5 Topics: Analgesics; Animals; Diphenhydramine; Drug Combinations; Hindlimb; Histamine H1 Antagonists; Hot Temperature; Injections, Intraperitoneal; Male; MSH Release-Inhibiting Hormone; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Tail	1998
Potentiation of anaphylaxis in guinea pig ileal mucosa by a selective delta-opioid receptor agonist. European journal of pharmacology, 1999, Aug-20, Volume: 379, Issue:1 Topics: Analgesics; Anaphylaxis; Animals; Anti-Allergic Agents; Cricetinae; Diphenhydramine; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Ileum; In Vitro Techniques; Lactoglobulins; Male; Milk; Mucous Membrane; Naloxone; Narcotic Antagonists; Ovalbumin; Saxitoxin	1999
Possible role of mast cells in cineole-induced scratching behavior in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:10 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Cyclohexanols; Cyproheptadine; Diphenhydramine; Eucalyptol; Histamine H1 Antagonists; Male; Mast Cells; Mice; Monoterpenes; Naloxone; p-Methoxy-N-methylphenethylamine; Purinergic P1 Receptor Agonists; Serotonin Antagonists; Terpenes; Theophylline	2002
The effects of sufentanil in the feline pulmonary vascular bed. European journal of pharmacology, 2006, Mar-18, Volume: 534, Issue:1-3 Topics: Analgesics, Opioid; Animals; Cats; Diphenhydramine; Dose-Response Relationship, Drug; Histamine Antagonists; Lung; Naloxone; Narcotic Antagonists; Pulmonary Artery; Pulmonary Circulation; Sufentanil; Vascular Resistance; Vasodilation; Vasodilator Agents	2006
Study on the antinociceptive action of Tyr-K-MIF-1, a peptide from the MIF family. Autonomic & autacoid pharmacology, 2007, Volume: 27, Issue:2 Topics: Analgesics; Animals; Dimaprit; Diphenhydramine; Famotidine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Methylhistamines; MSH Release-Inhibiting Hormone; Naloxone; Narcotic Antagonists; Pain Measurement; Pain Threshold; Rats; Rats, Wistar	2007
Morphine, opioids, and the feline pulmonary vascular bed. Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7 Topics: Analgesics, Opioid; Animals; Blood Pressure; Cats; Diphenhydramine; Dose-Response Relationship, Drug; Drug Interactions; Female; Fentanyl; Glyburide; Lung; Male; Meperidine; Morphine; Naloxone; Ornithine; Piperidines; Prospective Studies; Pulmonary Artery; Pulmonary Circulation; Remifentanil; Sufentanil; Sulfonamides; Vasodilation; Vasodilator Agents	2008
Use of tracking drugs for the search of intra-hospital adverse reactions: a pharmacovigilance study. Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2022, 04-26, Volume: 46, Issue:3 Topics: Adverse Drug Reaction Reporting Systems; Cross-Sectional Studies; Diphenhydramine; Drug-Related Side Effects and Adverse Reactions; Flumazenil; Hospitals; Humans; Loperamide; Naloxone; Pharmacovigilance; Promethazine	2022