diphenhydramine and morphine

diphenhydramine has been researched along with morphine in 85 studies

Research

Studies (85)

Timeframe	Studies, this research(%)	All Research%
pre-1990	52 (61.18)	18.7374
1990's	2 (2.35)	18.2507
2000's	19 (22.35)	29.6817
2010's	11 (12.94)	24.3611
2020's	1 (1.18)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Strassburg, CP; Tukey, RH	1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Nagashima, R; Nishikawa, T; Tobita, M	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Bellman, K; Knegtel, RM; Settimo, L	1
Rankovic, Z	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Boezio, A; Butler, JR; Foti, RS; Kornecook, T; Ligutti, J; Milgram, BC; Moyer, BD; Rescourio, G; Shimanovich, R; Taborn, K; Weiss, M; Youngblood, BD; Yu, V	1
Brown, M; Rivier, C; Vale, W	1
Rivier, C; Vale, W	1
Dibai, MA; Khoyi, MA; Salimi, M	1
Mosnaim, AD; Ungar, B; Ungar, F; Wolf, ME	1
Muraki, T; Tokunaga, Y	1
Aleksandrov, PN; Speranskaia, TV	1
Ehrenpreis, S; Kimura, I; Kimura, M; Kobayashi, T	1
Hanig, JP; Hui, FW; Sun, CL	1
Gallus, JA; Nearchou, NI; Poling, A; Sewell, RG	1
Hoshi, T; Kitazawa, T; Kondo, H; Temma, K	1
Castellano, C; D'Amato, FR; Sansone, M	1
D'Udine, B; Renzi, P; Sansone, M; Vetulani, J	1
Aly, F; el-Sawey, A; Fayez, M	1
Corrêa, FM; Pelá, IR; Ueta, J	1
Bell, S; Jhamandas, K; Sutak, M	1
Lin, Y; Tanaka, K	1
Foldes, FF	1
Hartmann, E	1
Park, WK; Regoli, D; Rioux, F	1
Saarnivaara, L	1
Gautieri, RF; Iuliucci, JD	1
Higgins, TN; Taylor, JD	1
Kabeno, H; Kobayashi, Y; Tachibana, K	1
Correa, FM; Graeff, FG	1
Pavan, WL	1
Gilev, AP; Vysokovskiĭ, TM	1
Ballinger, B; O'Malley, K; Stevenson, IH; Turnbull, MJ	1
Elkin, M; Kaplan, N; Newman, HR; Sharkey, J	1
Ibrahim, I; Sulman, FG; Weller, CP	1
Takagi, K; Takayanagi, I	1
Bruzzese, T; Casadio, S; Coppi, G; Pala, G; Turba, C	1
Akins, CW; Kono, K; Moss, J; Philbin, DM; Rosow, CE; Savarese, JJ; Schneider, RC; VerLee, TR	1
Akins, CW; Moss, J; Philbin, DM; Rosenberger, JL; Rosow, CE	1
Primor, N	1
Shannon, HE; Su, TP	1
Chung, YH; Kamei, C; Miyake, H; Tasaka, K	1
Ganes, EM; Jenkins, JT; Lind, RE; Reynolds, DG	1
Campos, VM; Solis, EL	1
Ali, B; Bhargava, KP; Gupta, KP; Kumar, A	1
Bartolini, A; Galeotti, N; Ghelardini, C	1
Alhashemi, JA; Crosby, ET; Duffy, PJ; Gallant, C; Grodecki, W; Hull, KA	1
Gregg, T; Gunter, JB; McAuliffe, J; Sweeney, DM; Varughese, AM; Weidner, N	1
Chan, WH; Chen, LK; Chen, YP; Lin, CJ; Lin, CS; Sun, WZ; Tsai, SK; Wang, MJ; Yeh, HM	1
Beyer, JE; Jacob, E; Miaskowski, C; Savedra, M; Styles, L; Treadwell, M	1
Cantrell, FL	1
HOLTEN, CH	1
VALENTINOVICH, EM	1
CARPENTER, CL; DERBES, VJ; NEDER, GA; ZISKIND, MM	1
COLLINS, RJ; MACGREGOR, DW; WEEKS, JR	1
DEJONGE, MC; DONNER, R; FUNCKE, AB; HARMS, AF; MULDER, D; NAUTA, WT; RUEMKE, CL; TERSTEEGE, HM	1
JACOBSON, ED; KALAS, JP	1
KARAS, JS; STANBURY, JB	1
ERICKSON, RW; GREEN, H	1
HERZ, A; HOFSTETTER, A; KURZ, H; TESCHEMACHER, H	1
Lin, CJ; Lin, TF; Sun, WZ; Wang, YP; Yeh, YC; Yen, YH	1
Baskurt, OK; Batu, O; Meiselman, HJ; Ozdem, SS; Tayfun, F; Yalcin, O	1
An, SL; Mo, ZX; Zhou, JY	1
HOUGS-OLSEN, W	1
Anwar, M; Bajwa, A; Baluch, A; Chilian, W; Fields, AM; Fox, C; Hoover, JM; Huffman, S; Ibrahim, IN; Kaye, AD; Kaye, AJ	1
DENTON, JE; STRAUS, OH	1
Baxendale, J; Bolognese, J; Calder, N; Connell, J; Cummings, C; Herman, G; Kehler, A; Wang, H	1
Baran, E; Enginar, N; Karamürsel, Y; Nurten, A; Zengin, A	1
Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW	1
EISENMAN, AJ; ISBELL, H	1
Jean, WH; Lin, TY; Lu, CW; Shieh, JS; Wu, CC	1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M	1

Reviews

5 review(s) available for diphenhydramine and morphine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
CNS drug design: balancing physicochemical properties for optimal brain exposure. Journal of medicinal chemistry, 2015, Mar-26, Volume: 58, Issue:6 Topics: Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Central Nervous System Agents; Drug Design; Humans; Models, Molecular; Permeability	2015
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Neuroleptanesthesia for general surgery. International anesthesiology clinics, 1973,Fall, Volume: 11, Issue:3 Topics: Alphaprodine; Anesthesia, Inhalation; Diphenhydramine; Droperidol; Female; Fentanyl; Humans; Hypertension; Hypotension; Injections, Intravenous; Male; Meperidine; Middle Aged; Morphine; Neuroleptanalgesia; Neuromuscular Nondepolarizing Agents; Nitrous Oxide; Preanesthetic Medication; Respiration; Respiration, Artificial; Respiratory Insufficiency; Scopolamine; Surgical Procedures, Operative	1973
Pharmacological studies of sleep and dreaming: chemical and clinical relationships. Biological psychiatry, 1969, Volume: 1, Issue:3 Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan	1969

Trials

10 trial(s) available for diphenhydramine and morphine

Article	Year
The use of H1 and H2 histamine antagonists with morphine anesthesia: a double-blind study. Anesthesiology, 1981, Volume: 55, Issue:3 Topics: Blood Pressure; Cardiac Output; Central Venous Pressure; Cimetidine; Clinical Trials as Topic; Coronary Artery Bypass; Diphenhydramine; Double-Blind Method; Drug Antagonism; Guanidines; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Middle Aged; Morphine; Placebos; Preanesthetic Medication; Vascular Resistance	1981
Histamine release with intravenous narcotics: protective effects of H1 and H2-receptor antagonists. Klinische Wochenschrift, 1982, Sep-01, Volume: 60, Issue:17 Topics: Cimetidine; Diphenhydramine; Double-Blind Method; Fentanyl; Hemodynamics; Histamine Release; Humans; Morphine; Phenylephrine; Random Allocation	1982
The analgesic and hypothermic effects of nefopam, morphine, aspirin, diphenhydramine, and placebo. Journal of clinical pharmacology, 1980, Volume: 20, Issue:1 Topics: Administration, Oral; Analgesics; Aspirin; Body Temperature; Diphenhydramine; Double-Blind Method; Humans; Injections, Intramuscular; Morphine; Nefopam; Oxazocines; Placebos; Time Factors	1980
Treatment of intrathecal morphine-induced pruritus following caesarean section. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:10 Topics: Adult; Analgesics, Opioid; Antipruritics; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Humans; Injections, Spinal; Morphine; Nalbuphine; Patient Satisfaction; Postoperative Complications; Pregnancy; Prospective Studies; Pruritus	1997
Continuous epidural butorphanol relieves pruritus associated with epidural morphine infusions in children. Paediatric anaesthesia, 2000, Volume: 10, Issue:2 Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Antipruritics; Bupivacaine; Butorphanol; Chi-Square Distribution; Child; Child, Preschool; Consciousness; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Follow-Up Studies; Histamine H1 Antagonists; Humans; Hydromorphone; Incidence; Injections, Epidural; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studies; Pruritus	2000
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. Anesthesia and analgesia, 2000, Volume: 91, Issue:1 Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Antiemetics; Antipruritics; Bupivacaine; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Humans; Injections, Spinal; Middle Aged; Morphine; Ondansetron; Pregnancy; Prospective Studies; Pruritus; Serotonin Antagonists	2000
Antiemetic and analgesic-sparing effects of diphenhydramine added to morphine intravenous patient-controlled analgesia. British journal of anaesthesia, 2005, Volume: 94, Issue:6 Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Diphenhydramine; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Hysterectomy; Infusions, Intravenous; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting	2005
Effect of morphine and pregabalin compared with diphenhydramine hydrochloride and placebo on hyperalgesia and allodynia induced by intradermal capsaicin in healthy male subjects. The journal of pain, 2008, Volume: 9, Issue:12 Topics: Adolescent; Adult; Alkaloids; Analgesics; Analgesics, Opioid; Analysis of Variance; Capsaicin; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Drug Administration Routes; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Hypnotics and Sedatives; Injections, Intradermal; Injections, Intravenous; Male; Middle Aged; Morphine; Pain; Pain Measurement; Placebos; Pregabalin; Treatment Outcome; Young Adult	2008
Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:6 Topics: Adult; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Ondansetron; Pain, Postoperative; Patient Satisfaction; Postoperative Nausea and Vomiting; Pregnancy; Pruritus; Recurrence; Serotonin Antagonists; Severity of Illness Index	2010
Antiemetic efficacy of metoclopramide and diphenhydramine added to patient-controlled morphine analgesia: a randomised controlled trial. European journal of anaesthesiology, 2010, Volume: 27, Issue:12 Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Dexamethasone; Diphenhydramine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hysterectomy; Metoclopramide; Middle Aged; Morphine; Pain, Postoperative; Postoperative Nausea and Vomiting; Prochlorperazine	2010

Other Studies

70 other study(ies) available for diphenhydramine and morphine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids. Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20 Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Discovery of pyridyl urea sulfonamide inhibitors of Na Bioorganic & medicinal chemistry letters, 2022, 10-01, Volume: 73 Topics: Humans; NAV1.7 Voltage-Gated Sodium Channel; Pain; Quinolones; Structure-Activity Relationship; Sulfanilamide; Sulfonamides; Urea; Voltage-Gated Sodium Channel Blockers	2022
Effect of neurotensin, substance P and morphine sulfate on the secretion of prolactin and growth hormone in the rat. Endocrinology, 1977, Volume: 100, Issue:3 Topics: Animals; Diphenhydramine; Estrogens; Growth Hormone; Male; Morphine; Naloxone; Neurotensin; Progesterone; Prolactin; Rats; Secretory Rate; Substance P; Thyrotropin-Releasing Hormone	1977
Effects of gamma-aminobutyric acid and histamine on prolactin secretion in the rat. Endocrinology, 1977, Volume: 101, Issue:2 Topics: Aminobutyrates; Animals; Bicuculline; Cells, Cultured; Clonidine; Diphenhydramine; Dopamine; Drug Interactions; Estrogens; gamma-Aminobutyric Acid; Haloperidol; Histamine; Male; Morphine; Naloxone; Nerve Tissue Proteins; Phenoxybenzamine; Pituitary Gland; Progesterone; Prolactin; Rats; Thyrotropin-Releasing Hormone	1977
Effect of ethacrynic acid on guinea pig ileum. Japanese journal of pharmacology, 1979, Volume: 29, Issue:2 Topics: Animals; Atropine; Diphenhydramine; Dose-Response Relationship, Drug; Electric Stimulation; Ethacrynic Acid; Guinea Pigs; Ileum; In Vitro Techniques; Methysergide; Morphine; Muscle Contraction; Muscle, Smooth; Tetrodotoxin	1979
Tyramine-binding by synaptosomes from rat brain: effect of centrally active drugs. Biological psychiatry, 1977, Volume: 12, Issue:5 Topics: Animals; Brain; Chlorpromazine; Desipramine; Dextroamphetamine; Diphenhydramine; Male; Morphine; Rats; Synaptosomes; Tyramine	1977
Effects of morphine on the serum prolactin levels of morphine-tolerant and nontolerant male rats and of the in vitro release of pituitary prolactin. Japanese journal of pharmacology, 1978, Volume: 28, Issue:6 Topics: Animals; Apomorphine; Diphenhydramine; Dopamine; Drug Tolerance; Haloperidol; In Vitro Techniques; Male; Morphine; Naloxone; Pituitary Gland, Anterior; Prolactin; Rats	1978
[The effect of serotonin and histamine antagonists on the inflammatory process in the living organism]. Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 79, Issue:3 Topics: Animals; Cricetinae; Diphenhydramine; Lysergic Acid Diethylamide; Male; Microcirculation; Morphine; Mouth Mucosa; Radiation Injuries, Experimental; Radiation-Protective Agents; Serotonin Antagonists; Ultraviolet Rays	1975
Histamine release as the basis for morphine action on bile duct and sphincter of Oddi. Life sciences, 1987, Apr-27, Volume: 40, Issue:17 Topics: Animals; Bile Ducts; Burimamide; Diphenhydramine; Histamine Release; In Vitro Techniques; Male; Morphine; Naloxone; p-Methoxy-N-methylphenethylamine; Sphincter of Oddi; Swine	1987
Effect of H1 blockers alone and in combination with morphine to produce antinociception in mice. Neuropharmacology, 1985, Volume: 24, Issue:1 Topics: Analgesics; Animals; Chlorpheniramine; Cyclizine; Diphenhydramine; Drug Synergism; Histamine H1 Antagonists; Male; Mice; Morphine; Phenothiazines; Pyrilamine	1985
Lethality of opioid and antihistaminic combinations in mice. Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:2 Topics: Animals; Diphenhydramine; Drug Synergism; Female; Histamine H1 Antagonists; Mice; Morphine; Narcotics; Pentazocine; Tripelennamine	1985
Effects of morphine and methionine-enkephalin on the smooth muscle tonus and the contraction induced by transmural stimulation in the carp (Cyprinus carpio) intestinal bulb. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1986, Volume: 84, Issue:2 Topics: Acetylcholine; Animals; Atropine; Carps; Diphenhydramine; Electric Stimulation; Enkephalin, Methionine; Female; Hexamethonium; Hexamethonium Compounds; Intestines; Isometric Contraction; Male; Morphine; Muscle Contraction; Muscle Tonus; Naloxone; Tetrodotoxin	1986
Enhancement of morphine-induced hyperactivity by antihistaminic drugs in mice. Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 284, Issue:2 Topics: Animals; Chlorpheniramine; Diphenhydramine; Histamine H1 Antagonists; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Tripelennamine	1986
Antihistaminics enhance morphine-, but not amphetamine- and scopolamine-induced hyperactivity in mice. Psychopharmacology, 1987, Volume: 93, Issue:2 Topics: Animals; Chlorpheniramine; Dextroamphetamine; Diphenhydramine; Drug Synergism; Histamine H1 Antagonists; Hyperkinesis; Male; Mice; Morphine; Scopolamine; Tripelennamine	1987
Antagonization of tetramisole toxicity by hexamethonium. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl Topics: Animals; Atropine; Blood Pressure; Diphenhydramine; Dogs; Female; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Male; Morphine; Rats; Reference Values; Tetramisole	1987
Central adrenergic mediation of the cardiovascular effect of intraventricular bradykinin. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 333, Issue:2 Topics: Animals; Blood Pressure; Bradykinin; Diphenhydramine; Drug Interactions; Injections, Intraventricular; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Septal Nuclei	1986
Modification of precipitated morphine withdrawal syndrome by drugs affecting cholinergic mechanisms. European journal of pharmacology, 1973, Volume: 24, Issue:3 Topics: Animals; Atropine; Autonomic Nervous System; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imipramine; Mecamylamine; Morphine; Morphine Dependence; Naloxone; Neurotransmitter Agents; Physostigmine; Propranolol; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Substance Withdrawal Syndrome; Synaptic Transmission; Tolazoline	1973
Histamine liberation into the cerebrospinal fluid by the drugs applied intraventricularly. Japanese journal of pharmacology, 1969, Volume: 19, Issue:4 Topics: Alkaloids; Animals; Blood Pressure; Cerebral Ventricles; Diphenhydramine; Histamine; Histamine Release; Hypertension; Morphine; Perfusion; Rabbits; Respiration; Spectrophotometry; Tubocurarine; Veratrine	1969
Application of drug-receptor theories to angiotensin. Canadian journal of physiology and pharmacology, 1973, Volume: 51, Issue:9 Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Atropine; Cocaine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; In Vitro Techniques; Indomethacin; Methysergide; Morphine; Muscle Contraction; Muscle, Smooth; Peptides; Phentolamine; Prostaglandins; Rabbits; Rats; Receptors, Cell Surface; Receptors, Drug; Serotonin; Stomach; Structure-Activity Relationship	1973
Influence of some drugs on the accumulation of morphine in rabbit red cells in vitro. Annales medicinae experimentalis et biologiae Fenniae, 1969, Volume: 47, Issue:2 Topics: Analgesia; Animals; Cyproheptadine; Diphenhydramine; Dopamine; Drug Synergism; Erythrocytes; Hemolysis; Histamine H1 Antagonists; Imipramine; In Vitro Techniques; Indomethacin; Isotonic Solutions; Male; Morphine; Norepinephrine; Phenothiazines; Pyrrolidines; Rabbits; Serotonin	1969
Morphine-induced fetal malformations. II. Influence of histamine and diphenhydramine. Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:3 Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cryptorchidism; Diphenhydramine; Drug Synergism; Female; Fetus; Gestational Age; Histamine; Male; Mice; Morphine; Pregnancy; Skull; Sulfates	1971
Optimization of extraction and separation of narcotics from urine. Clinical biochemistry, 1974, Volume: 7, Issue:3 Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Codeine; Diphenhydramine; Evaluation Studies as Topic; Glucosidases; Humans; Indicators and Reagents; Meperidine; Methadone; Methaqualone; Methods; Morphine; Nalorphine; Narcotics; Nicotine; Pentazocine; Phenmetrazine; Time Factors	1974
Studies on gastrointestinal hormones. X. Effects of tetragastrin on gastric secretion and isolated smooth muscles. Japanese journal of pharmacology, 1973, Volume: 23, Issue:2 Topics: Animals; Atropine; Cholinesterase Inhibitors; Diphenhydramine; Epinephrine; Gastric Mucosa; Gastrins; Guinea Pigs; Hexamethonium Compounds; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Physostigmine; Rats; Semicarbazides	1973
Central mechanisms of the hypertensive action of intraventricular bradykinin in the unanaesthetized rat. Neuropharmacology, 1974, Volume: 13, Issue:1 Topics: Alkaloids; Amides; Animals; Atropine; Behavior, Animal; Benzyl Compounds; Blood Pressure; Bradykinin; Catechols; Catheterization; Cerebral Ventricles; Diphenhydramine; Eledoisin; Ethylenediamines; Fatty Acids, Unsaturated; Hexamethonium Compounds; Injections; Injections, Intra-Arterial; Kallidin; Lysergic Acid Diethylamide; Male; Methysergide; Morphine; Norepinephrine; Phentolamine; Propranolol; Pyridines; Rats; Stereotaxic Techniques; Time Factors	1974
[Doloxene: comparative study of analgesia produced by morphine sulfate, codeine phosphate, meperidine hydrochloride and Doloxene in mice. Potentiation of its analgesia with diphenhydramine (Benadryl) and promethazine (Phenergan)]. Hospital (Rio de Janeiro, Brazil), 1966, Volume: 69, Issue:3 Topics: Analgesics; Animals; Codeine; Diphenhydramine; Drug Synergism; Meperidine; Mice; Morphine; Promethazine	1966
[Effect of peripheral serotonin antagonists on changes in the background bioelectric activity of the rat cerebral cortex caused by 5-hydroxytryptophan]. Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 70, Issue:11 Topics: 5-Hydroxytryptophan; Animals; Cerebral Cortex; Diphenhydramine; Electroencephalography; Indoles; Mesencephalon; Morphine; Rats; Reticular Formation; Serotonin Antagonists	1970
Stimulation of drug metabolism by centrally active drugs. British journal of pharmacology, 1971, Volume: 41, Issue:2 Topics: Amphetamine; Animals; Barbiturates; Benzazepines; Chlordiazepoxide; Diphenhydramine; Enzyme Induction; Ethanol; In Vitro Techniques; Meprobamate; Methaqualone; Microsomes, Liver; Morphine; Pyridones; Rats	1971
The role of potassium in ureteral physiology and pharmacology. Investigative urology, 1968, Volume: 6, Issue:2 Topics: Action Potentials; Animals; Diphenhydramine; Dogs; Epinephrine; Female; Histamine; Isoproterenol; Meperidine; Morphine; Muscle Contraction; Muscle, Smooth; Potassium; Stimulation, Chemical; Sympatholytics; Ureter	1968
Analgesic profile of tranquillizers in multiple screening tests in mice. Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1 Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents	1968
Effects of aromatic nitrocompounds and phenolderivatives on the cholinergic nerve ending of smooth muscle and skeletal muscle. Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:2 Topics: Animals; Anura; Atropine; Benzoates; Diphenhydramine; Electrokymography; Guinea Pigs; Hexamethonium Compounds; Histamine; In Vitro Techniques; Intestine, Small; Morphine; Muscle, Smooth; Nerve Endings; Nitrophenols; Parasympathetic Nervous System; Phenols; Physostigmine; Picrates	1965
Hypoglycemic activity and pharmacological picture of 4-(1-naphthyl)butylamine derivatives. Journal of medicinal chemistry, 1966, Volume: 9, Issue:5 Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Glucose; Blood Pressure; Butylamines; Chemistry, Organic; Chlorpromazine; Chlorpropamide; Cocaine; Cough; Diphenhydramine; Diuresis; Edema; Guinea Pigs; Hexamethonium Compounds; Histamine; Hydrochlorothiazide; Morphine; Naphthalenes; Nicotine; Organic Chemistry Phenomena; Phenylbutazone; Rats; Serotonin; Spasm	1966
Pardaxin produces postjunctional muscle contraction in guinea-pig intestinal smooth muscle. British journal of pharmacology, 1984, Volume: 82, Issue:1 Topics: Acetylcholine; Animals; Diphenhydramine; Drug Interactions; Electric Stimulation; Fish Venoms; Guinea Pigs; In Vitro Techniques; Isometric Contraction; Morphine; Muscle Contraction; Muscle, Smooth; Nicotine; Physostigmine; Serotonin; Spider Venoms; Substance P	1984
Effects of the combination of tripelennamine and pentazocine at the behavioral and molecular levels. Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:4 Topics: Animals; Brain; Diphenhydramine; Discrimination, Psychological; Drug Synergism; Guinea Pigs; Ileum; Learning; Male; Morphine; Pentazocine; Phenazocine; Rats; Receptors, Opioid; Synaptic Membranes; Tripelennamine	1982
Analgesic effect of histamine induced by intracerebral injection into mice. Agents and actions, 1984, Volume: 15, Issue:3-4 Topics: Analgesics; Animals; Benzoquinones; Cimetidine; Diphenhydramine; Electric Stimulation; Enkephalin, Leucine; Histamine; Histamine Antagonists; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Promethazine; Pyrilamine; Quinones; Reaction Time	1984
Morphine effects on cardiovascular performance. The American surgeon, 1981, Volume: 47, Issue:3 Topics: Animals; Autonomic Nervous System; Cardiovascular System; Cimetidine; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Heart; Hemodynamics; Morphine; Naloxone	1981
Differential stimulation of diphenhydramine, pethidine, morphine and aniline metabolism by chronic methaqualone treatment. Pharmacology, 1980, Volume: 20, Issue:4 Topics: Aniline Compounds; Animals; Diphenhydramine; Drug Interactions; In Vitro Techniques; Male; Meperidine; Methaqualone; Microsomes, Liver; Morphine; Proteins; Rats	1980
Effect of pertussis toxin on morphine, diphenhydramine, baclofen, clomipramine and physostigmine antinociception. European journal of pharmacology, 1996, Jul-18, Volume: 308, Issue:2 Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Baclofen; Cholinesterase Inhibitors; Clomipramine; Diphenhydramine; Drug Antagonism; GABA Agonists; Histamine H1 Antagonists; Injections, Intraventricular; Male; Mice; Morphine; Pain Measurement; Pertussis Toxin; Physostigmine; Virulence Factors, Bordetella	1996
Management of vaso-occlusive pain in children with sickle cell disease. Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:4 Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anemia, Sickle Cell; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diphenhydramine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Ischemia; Ketorolac; Longitudinal Studies; Male; Morphine; Pain; Pain Management; Pain Measurement; Patient Satisfaction; Self Administration; Treatment Failure	2003
Envenomation by the Mexican beaded lizard: a case report. Journal of toxicology. Clinical toxicology, 2003, Volume: 41, Issue:3 Topics: Adult; Anaphylaxis; Animals; Bites and Stings; Diphenhydramine; Edema; Emergency Treatment; Humans; Lizards; Male; Methylprednisolone; Morphine; Pain; Treatment Outcome; Venoms	2003
Inhibitory effect of benactyzine derivatives and other compounds on the Straub-Herrmann mouse tail reaction due to morphine. Acta pharmacologica et toxicologica, 1957, Volume: 13, Issue:2 Topics: Animals; Benactyzine; Diphenhydramine; Mice; Morphine; Tranquilizing Agents	1957
[Acid erythrograms as a method for the clinical evaluation of the functional state of the body during the use of potentiating substances]. Zdravookhranenie Kazakhstana, 1962, Volume: 22(7) Topics: Atropine; Chlorpromazine; Diphenhydramine; Erythrocytes; Meperidine; Morphine	1962
DEATH IN STATUS ASTHMATICUS. ROLE OF SEDATION. Diseases of the chest, 1963, Volume: 44 Topics: Amobarbital; Asthma; Chloral Hydrate; Codeine; Diphenhydramine; Hydromorphone; Hypnotics and Sedatives; Meperidine; Morphine; Mortality; Phenobarbital; Status Asthmaticus; Toxicology	1963
AN ATTEMPT TO DEMONSTRATE CEILING EFFICACY OF ANALGESICS IN RATS. Archives internationales de pharmacodynamie et de therapie, 1964, Jan-01, Volume: 147 Topics: Aminopyrine; Amphetamine; Amphetamines; Analgesics; Aspirin; Barbiturates; Chlordiazepoxide; Chlorpromazine; Codeine; Dextropropoxyphene; Diphenhydramine; Meperidine; Meprobamate; Methadone; Morphine; Pharmacology; Phenobarbital; Rats; Rectum; Research; Toxicology	1964
INVESTIGATION OF 3-(10,11-DIHYDRO-5H-DIBENZO (A,D) CYCLOHEPTEN-5-YLOXY) TROPANE CITRATE (DIBENZHEPTROPINE CITRATE, BRONTINE). I. PHARMACOLOGICAL PROPERTIES. II. TOXICOLOGICAL PROPERTIES. Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148 Topics: Acetylcholine; Albumins; Animals; Asthma; Atropine; Bronchi; Citric Acid; Cyproheptadine; Diphenhydramine; Dogs; Edema; Fever; Gastric Juice; Guinea Pigs; Heterocyclic Compounds; Hexobarbital; Histamine H1 Antagonists; Morphine; Muscle Relaxants, Central; Parasympatholytics; Pentylenetetrazole; Pharmacology; Pupil; Quaternary Ammonium Compounds; Rabbits; Rats; Research; Salivation; Serotonin; Toxicology; Tranquilizing Agents; Tropanes	1964
THE EFFECT OF VASOACTIVE ANTAGONISTS IN ENDOTOXIN SHOCK. American heart journal, 1964, Volume: 67 Topics: Animals; Atropine; Blood Circulation; Blood Pressure; Blood Pressure Determination; Chloralose; Cyproheptadine; Diphenhydramine; Dogs; Endotoxins; Hemorrhage; Histamine H1 Antagonists; Histamine Release; Humans; Hypertension; Hypertension, Portal; Isoproterenol; Morphine; p-Methoxy-N-methylphenethylamine; Pharmacology; Phenothiazines; Phenoxybenzamine; Piperidines; Research; Reserpine; Shigella; Shock, Septic; Splenic Artery; Sympatholytics; Vasodilator Agents	1964
FATAL RADIATION SYNDROME FROM AN ACCIDENTAL NUCLEAR EXCURSION. The New England journal of medicine, 1965, Apr-15, Volume: 272 Topics: Accidents; Accidents, Occupational; Angiotensins; Blood Cell Count; Blood Chemical Analysis; Bone Marrow Cells; Chloramphenicol; Dimenhydrinate; Diphenhydramine; Drug Therapy; Electrocardiography; Emergency Service, Hospital; Hemoglobinometry; Humans; Mannitol; Metaraminol; Methylprednisolone; Morphine; Neomycin; Norepinephrine; Radiation Injuries; Radiation Protection; Uranium	1965
EFFECT OF SOME DRUGS UPON RAT BRAIN HISTAMINE CONTENT. International journal of neuropharmacology, 1964, Volume: 3 Topics: Antidepressive Agents; Aspirin; Benactyzine; Brain; Brain Chemistry; Chemistry Techniques, Analytical; Chlorpheniramine; Dextroamphetamine; Diphenhydramine; Fluorescence; Fluorometry; Histamine; Morphine; Pharmacology; Rats; Research; Tranquilizing Agents; Tranylcypromine; Tripelennamine	1964
THE IMPORTANCE OF LIPID-SOLUBILITY FOR THE CENTRAL ACTION OF CHOLINOLYTIC DRUGS. International journal of neuropharmacology, 1965, Volume: 4 Topics: Atropine; Benactyzine; Blood-Brain Barrier; Brain; Cholinergic Antagonists; Diphenhydramine; Electroencephalography; Lipids; Mice; Morphine; Orphenadrine; Parasympatholytics; Parasympathomimetics; Pharmacology; Pupil; Rabbits; Rats; Research; Scopolamine; Solubility	1965
The effect of morphine in rat small mesenteric arteries. Vascular pharmacology, 2005, Volume: 43, Issue:1 Topics: Animals; Calcium; Diphenhydramine; Endothelium, Vascular; Enzyme Inhibitors; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Morphine; Muscle, Smooth, Vascular; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Vascular Resistance; Vasoconstrictor Agents	2005
[Effects of Caulis Sinomenii and sinomenine on morphine-induced place preference and brain histamine level in mice]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2006, Volume: 26, Issue:12 Topics: Animals; Arginine; Brain; Conditioning, Operant; Diphenhydramine; Histamine; Male; Mice; Morphinans; Morphine; Morphine Dependence; Motor Activity; Random Allocation; Sinomenium	2006
Comparative investigations in to the analgesic effects of morphine and d, 1-6-dimethylamino-4,4-diphenyl-3-heptanone hydrochloride. Acta pharmacologica et toxicologica, 1949, Volume: 5, Issue:1 Topics: Analgesics; Biphenyl Compounds; Diphenhydramine; Humans; Ketones; Methadone; Morphine	1949
Morphine, opioids, and the feline pulmonary vascular bed. Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:7 Topics: Analgesics, Opioid; Animals; Blood Pressure; Cats; Diphenhydramine; Dose-Response Relationship, Drug; Drug Interactions; Female; Fentanyl; Glyburide; Lung; Male; Meperidine; Morphine; Naloxone; Ornithine; Piperidines; Prospective Studies; Pulmonary Artery; Pulmonary Circulation; Remifentanil; Sufentanil; Sulfonamides; Vasodilation; Vasodilator Agents	2008
A comparison of side actions and analgesic effects of morphine, amidone, (4-4-diphenyl-6-dimethylamino-heptanone-3) and its isomers in man. Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1 Topics: Analgesics; Biphenyl Compounds; Diphenhydramine; Isomerism; Ketones; Methadone; Morphine; Morphine Derivatives	1948
Scopolamine-induced convulsions in fasted mice after food intake: evaluation of the sedative effect in the suppression of convulsions. Epilepsy research, 2010, Volume: 89, Issue:1 Topics: Amitriptyline; Animals; Body Weight; Chlorpromazine; Diphenhydramine; Eating; Food Deprivation; Hypnotics and Sedatives; Mice; Morphine; Scopolamine; Seizures	2010
Treatment of the morphine abstinence syndrome with 10820 (4-4-diphenyl-6-dimethylamino-heptanone-3). Federation proceedings, 1947, Volume: 6, Issue:1 Topics: Biphenyl Compounds; Diphenhydramine; Humans; Ketones; Morphine; Morphine Dependence	1947
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology. Journal of analytical toxicology, 2014, Volume: 38, Issue:8 Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry	2014