diphenhydramine and midazolam

diphenhydramine has been researched along with midazolam in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.33)18.7374
1990's1 (3.33)18.2507
2000's12 (40.00)29.6817
2010's15 (50.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Spealman, RD1
Gottlieb, A; Scheman, JD; Sprung, J1
Ludomirsky, A; Malviya, S; Marshall, J; Tait, AR; Voepel-Lewis, T1
Doan, C; Garcia, JC; Grewall, P; Leung, JW; Mann, S; Prindiville, T; Sheykhzadeh, PI; Suryaprasad, AG; Trudeau, W; Tu, RH; Zhang, N1
Baysal, Z; Cengiz, M; Ganidagli, S1
Ayrik, C; Erdur, B; Ergin, A; Ergin, N; Parlak, I; Parlak, M; Tomruk, O; Turkcuer, I1
Gardner, JC; Ririe, DG; Turner, CS1
Leung, FW; Leung, JW; Mann, S; Salera, R; Toomsen, L1
Garg, R; Husain, N; Roach, CL; Welch, E; Zabinsky, J1
Hendrickson, RG; Horowitz, BZ; McKeown, NJ; West, PL1
Aydin, B; Erdur, B; Ergin, A; Kabay, B; Ozen, M; Parlak, I; Tura, P1
Lim, BL; Qiu, LM1
Rodgers, MS; Rodgers, SF1
Cole, JB; Gross, EA; Smith, SW; Stellpflug, SJ1
Childers, RE; Sonnenberg, A; Williams, JL1
Laine, L; Nandigam, K; Pichetshote, N; Sachar, H; Vaidya, K1
Bashir, M; Bitar, H; Hanafi, M; Madhoun, M; Parava, P; Tierney, W; Zia, H1
Madhoun, MF; Nusrat, S; Tierney, WM1
El Shahawy, MS; El-Fayoumy, M1
Edmundowicz, SA; Faruki, AA; Hardesty, TD; Lemley, MG; Mariotti, AL; Pattee, J; Rist, SD; Sharma, SM; Weitzel, N1

Reviews

1 review(s) available for diphenhydramine and midazolam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

7 trial(s) available for diphenhydramine and midazolam

ArticleYear
Diphenhydramine as an adjunct to sedation for colonoscopy: a double-blind randomized, placebo-controlled study.
    Gastrointestinal endoscopy, 2006, Volume: 63, Issue:1

    Topics: Colonoscopy; Conscious Sedation; Diphenhydramine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Meperidine; Midazolam; Middle Aged; Patient Satisfaction; Prospective Studies; Treatment Outcome

2006
Oral sedation with midazolam and diphenhydramine compared with midazolam alone in children undergoing magnetic resonance imaging.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:6

    Topics: Administration, Oral; Anesthetics, Combined; Child; Child, Preschool; Conscious Sedation; Diphenhydramine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infant; Magnetic Resonance Imaging; Male; Midazolam; Prospective Studies

2006
Midazolam vs. diphenhydramine for the treatment of metoclopramide-induced akathisia: a randomized controlled trial.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2007, Volume: 14, Issue:8

    Topics: Adult; Akathisia, Drug-Induced; Analysis of Variance; Diphenhydramine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Metoclopramide; Midazolam; Middle Aged; Probability; Reference Values; Risk Assessment; Severity of Illness Index; Treatment Outcome

2007
A trial of midazolam vs diphenhydramine in prophylaxis of metoclopramide-induced akathisia.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:1

    Topics: Adult; Akathisia, Drug-Induced; Antiemetics; Diphenhydramine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Metoclopramide; Midazolam; Nausea; Severity of Illness Index; Treatment Outcome

2012
Continued midazolam versus diphenhydramine in difficult-to-sedate patients: a randomized double-blind trial.
    Gastrointestinal endoscopy, 2018, Volume: 87, Issue:5

    Topics: Anesthetics, Intravenous; Colonoscopy; Conscious Sedation; Diphenhydramine; Double-Blind Method; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intention to Treat Analysis; Male; Midazolam; Middle Aged

2018
Use of diphenhydramine as an adjunctive sedative for colonoscopy in patients on chronic opioid therapy: a randomized controlled trial.
    Gastrointestinal endoscopy, 2018, Volume: 88, Issue:4

    Topics: Aged; Analgesics, Opioid; Anesthetics, Intravenous; Colonoscopy; Deep Sedation; Diphenhydramine; Female; Fentanyl; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Pain, Procedural; Time Factors

2018
The Influence of Adding Diphenhydramine Before Initiation of Moderate Sedation with Midazolam and Pethidine for Improving Quality of Colonoscopy.
    Journal of the National Medical Association, 2019, Volume: 111, Issue:6

    Topics: Analgesics, Opioid; Attitude of Health Personnel; Colonoscopy; Conscious Sedation; Diphenhydramine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Male; Meperidine; Midazolam; Middle Aged; Operative Time; Patient Satisfaction; Prospective Studies; Visual Analog Scale

2019

Other Studies

22 other study(ies) available for diphenhydramine and midazolam

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Animals; Azabicyclo Compounds; Barbital; Benzodiazepines; Benzodiazepinones; Buspirone; Caffeine; Chlordiazepoxide; Cinanserin; Clozapine; Conditioning, Operant; Cyproheptadine; Diazepam; Diphenhydramine; Discrimination Learning; Electroshock; Flumazenil; Male; Midazolam; Muscimol; Nordazepam; Pentobarbital; Piperazines; Pyridazines; Pyrimidines; Saimiri; Tripelennamine

1985
Flashback and nightmares after surgery under neuraxial anesthesia: a report of two cases.
    Archives of physical medicine and rehabilitation, 1998, Volume: 79, Issue:5

    Topics: Adjuvants, Anesthesia; Aged; Amputation, Surgical; Anesthesia, Spinal; Anesthetics, Local; Arthroplasty, Replacement, Hip; Bupivacaine; Diphenhydramine; Dreams; Epinephrine; Female; Fentanyl; Humans; Midazolam; Middle Aged

1998
Can we improve the assessment of discharge readiness?: A comparative study of observational and objective measures of depth of sedation in children.
    Anesthesiology, 2004, Volume: 100, Issue:2

    Topics: Anesthesia Recovery Period; Child; Chloral Hydrate; Conscious Sedation; Diphenhydramine; Echocardiography; Humans; Midazolam; Patient Discharge; Predictive Value of Tests

2004
Vagal hypertonia and anesthesia in Angelman syndrome.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:4

    Topics: Adrenergic Agonists; Anaphylaxis; Androstanols; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Angelman Syndrome; Anti-Allergic Agents; Anti-Inflammatory Agents; Blood Pressure; Cardiopulmonary Resuscitation; Child; Diphenhydramine; Epinephrine; Female; Heart Arrest; Humans; Male; Methyl Ethers; Methylprednisolone; Midazolam; Monitoring, Physiologic; Neuromuscular Nondepolarizing Agents; Nitrous Oxide; Rocuronium; Sevoflurane; Tachycardia, Sinus; Vagus Nerve

2008
Pilot feasibility study of the method of water infusion without air insufflation in sedated colonoscopy.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:9

    Topics: Aged; Analgesics, Opioid; Colonoscopy; Diphenhydramine; Feasibility Studies; Fentanyl; Humans; Hypnotics and Sedatives; Midazolam; Middle Aged; Pilot Projects; Water

2009
Moderate sedation for echocardiography of preschoolers.
    Pediatric cardiology, 2010, Volume: 31, Issue:4

    Topics: Anesthesia, General; Child, Preschool; Chloral Hydrate; Conscious Sedation; Cost-Benefit Analysis; Diphenhydramine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Female; Humans; Hydroxyzine; Hypnotics and Sedatives; Male; Midazolam; Retrospective Studies

2010
Survival after diphenhydramine ingestion with hemodialysis in a toddler.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2011, Volume: 7, Issue:2

    Topics: Diphenhydramine; Humans; Hypnotics and Sedatives; Infant; Injections, Intramuscular; Male; Midazolam; Poisoning; Renal Dialysis; Seizures; Status Epilepticus; Tachycardia; Treatment Outcome

2011
Case of acute akathisia from intravenous metoclopramide.
    Singapore medical journal, 2011, Volume: 52, Issue:1

    Topics: Abdominal Pain; Adult; Akathisia, Drug-Induced; Diphenhydramine; Emergency Service, Hospital; Female; Gastroenteritis; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Metoclopramide; Midazolam; Psychomotor Agitation; Treatment Outcome

2011
Safety of intravenous sedation administered by the operating oral surgeon: the second 7 years of office practice.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:10

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Intravenous; Conscious Sedation; Deep Sedation; Diphenhydramine; Drug-Related Side Effects and Adverse Reactions; Female; Fentanyl; Follow-Up Studies; Humans; Male; Meperidine; Midazolam; Middle Aged; Postoperative Nausea and Vomiting; Propofol; Psychomotor Agitation; Retrospective Studies; Surgery, Oral; Syncope; Young Adult

2011
Wide complex tachycardia in a pediatric diphenhydramine overdose treated with sodium bicarbonate.
    Pediatric emergency care, 2011, Volume: 27, Issue:12

    Topics: Anticonvulsants; Cholinergic Antagonists; Diphenhydramine; Drug Overdose; Electrocardiography; Emergencies; Female; Heart Conduction System; Humans; Hypertonic Solutions; Infant; Midazolam; Seizures; Sodium Bicarbonate; Sodium Channel Blockers; Sodium Channels; Tachycardia, Sinus

2011
Practice patterns of sedation for colonoscopy.
    Gastrointestinal endoscopy, 2015, Volume: 82, Issue:3

    Topics: Adenoma; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Biopsy; Black or African American; Catheter Ablation; Cohort Studies; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; Conscious Sedation; Databases, Factual; Diazepam; Dilatation; Diphenhydramine; Early Detection of Cancer; Female; Fentanyl; Hispanic or Latino; Humans; Hypnotics and Sedatives; Linear Models; Male; Meperidine; Midazolam; Middle Aged; Multivariate Analysis; Pain Management; Practice Patterns, Physicians'; Promethazine; Propofol; Retrospective Studies; Stents; White People; Young Adult

2015
Impact of fellowship training level on colonoscopy quality and efficiency metrics.
    Gastrointestinal endoscopy, 2018, Volume: 88, Issue:2

    Topics: Adenoma; Adjuvants, Anesthesia; Aged; Clinical Competence; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; Diphenhydramine; Fellowships and Scholarships; Female; Fentanyl; Gastroenterology; Gastrointestinal Agents; Glucagon; Humans; Hypnotics and Sedatives; Male; Medical Staff, Hospital; Midazolam; Middle Aged; Operative Time; Retrospective Studies

2018
Operational outcomes of propofol sedation versus fentanyl, midazolam and diphenhydramine sedation for endoscopies and colonoscopies at an academic medical center.
    PloS one, 2023, Volume: 18, Issue:11

    Topics: Academic Medical Centers; Anesthesia; Colonoscopy; Conscious Sedation; Diphenhydramine; Fentanyl; Humans; Hypnotics and Sedatives; Midazolam; Propofol; Retrospective Studies

2023