Compounds > diphenhydramine

diphenhydramine and methyldopa

diphenhydramine has been researched along with methyldopa in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Claman, HN; Karr, RM; Kohler, PF; Mass, MF; McIntosh, RM; Sams, WM; Small, P; Stanford, RE; Thorne, EG1
HUDOCK, JJ; KHENTIGAN, A; LAWRENCE, W; VANAMEE, P1

Reviews

1 review(s) available for diphenhydramine and methyldopa

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for diphenhydramine and methyldopa

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Systemic (allergic?) vasculitis.
    The Journal of allergy and clinical immunology, 1974, Volume: 54, Issue:1

    Topics: Antigen-Antibody Complex; Azathioprine; Complement System Proteins; Creatinine; Diphenhydramine; Erythrocytes; Female; Fluorescent Antibody Technique; Humans; Hypertension; Immune Complex Diseases; Inflammation; Kidney Diseases; Kidney Glomerulus; Methyldopa; Microscopy, Electron; Middle Aged; Necrosis; Prednisone; Proteinuria; Skin; Skin Manifestations; Urine; Vascular Diseases

1974
THE EFFECT OF SEROTONIN AND SEROTONIN ANTAGONISTS ON EXTERNAL PANCREATIC SECRETION IN DOGS.
    The Journal of surgical research, 1963, Volume: 3

    Topics: Antihypertensive Agents; Cyproheptadine; Diphenhydramine; Dogs; Ergot Alkaloids; Ergotamine; Indoles; Methyldopa; Methylergonovine; Oxytocics; Pancreatic Juice; Prochlorperazine; Pyrimidines; Research; Reserpine; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Yohimbine

1963