diphenhydramine and methadone

diphenhydramine has been researched along with methadone in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199018 (52.94)18.7374
1990's0 (0.00)18.2507
2000's8 (23.53)29.6817
2010's7 (20.59)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Nagashima, R; Nishikawa, T; Tobita, M1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Haller, R; Weder, HG; Wiegand, UW2
Moffat, AC1
Ajel, LA1
Wilson, D1
Caddy, B; Fish, F; Mullen, PW; Tranter, J1
Carlsson, A; Lindqvist, M1
Hartvig, P; Vessman, J1
Higgins, TN; Taylor, JD1
Burnett, D; Goudie, JH; Sherriff, JM1
Lorenzetti, OJ; Sancilio, LF1
Kelner, MJ1
Pragst, F; Sporkert, F1
COLLINS, RJ; MACGREGOR, DW; WEEKS, JR1
Gallagher, R1
Corey, TS; Hunsaker Iii, JC; Shields, LB; Stewart, D; Ward, MK1
ISBELL, H; WILKER, A1
HOUGS-OLSEN, W1
DENTON, JE; STRAUS, OH1
FINNEGAN, JK; HAAG, HB; LARSON, PS1
CLOUSE, P; KOHLSTAEDT, KG1
Caravati, EM; Crouch, DJ; Pruitt, CW; Rogers, SC1
Flø, L; Hansen, SH; Janfelt, C; Pedersen-Bjergaard, S; Thunig, J1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1
Kintz, P1
Azbel, L; Lancaster, K; Meyer, J; Rhodes, T1
Benz, P; Farkas, A; Ryan, K; Theobald, J; Zosel, A1

Reviews

1 review(s) available for diphenhydramine and methadone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

33 other study(ies) available for diphenhydramine and methadone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Interactions of some parasympatholytics and structurally similar drugs with bovine serum albumin].
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:6

    Topics: Binding Sites; Dextropropoxyphene; Dialysis; Diphenhydramine; Diphenylacetic Acids; Kinetics; Methadone; Parasympatholytics; Propantheline; Protein Binding; Receptors, Drug; Serum Albumin, Bovine; Ultracentrifugation

1975
[Studies on the binding of some parasympatholytics to bovine serum albumin/measurement of relaxation times (author's transl)].
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:7

    Topics: Dextropropoxyphene; Diphenhydramine; Diphenylacetic Acids; Magnetic Resonance Spectroscopy; Methadone; Parasympatholytics; Propantheline; Protein Binding; Serum Albumin, Bovine

1975
Use of SE-30 as a stationary phase for the gas-liquid chromatography of drugs.
    Journal of chromatography, 1975, Mar-12, Volume: 113, Issue:1

    Topics: Absorption; Amphetamine; Chromatography, Gas; Diphenhydramine; Methadone; Methods; Pharmaceutical Preparations; Piperidines; Silicone Elastomers

1975
Positive diphenhydramine interference in the EMIT-d.a.u. assay.
    Clinical chemistry, 1985, Volume: 31, Issue:2

    Topics: Diphenhydramine; Humans; Immunoenzyme Techniques; Methadone

1985
Experience with drugs and driving in Queensland, Australia.
    Medicine, science, and the law, 1985, Volume: 25, Issue:1

    Topics: Australia; Automobile Driving; Diazepam; Diphenhydramine; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Ethanol; Humans; Legislation, Drug; Methadone; Methaqualone

1985
An oxidative analytical procedure for some compounds containing the diphenylmethylidene group.
    Journal - Forensic Science Society, 1973, Volume: 13, Issue:2

    Topics: Benzene Derivatives; Chromatography; Cyclizine; Diphenhydramine; Methadone; Methods; Orphenadrine; Oxidation-Reduction; Piperazines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1973
Central and peripheral monoaminergic membrane-pump blockade by some addictive analgesics and antihistamines.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:7

    Topics: 5-Hydroxytryptophan; Amines; Analgesics; Animals; Biological Transport, Active; Chlorpheniramine; Diphenhydramine; Histamine H1 Antagonists; Meperidine; Methadone; Mice; Neurons; Nialamide; Norepinephrine; Serotonin; Tripelennamine

1969
Electron capture gas chromatography of tertiary amines after a demethylation reaction to secondary amines. II. Studies of different chloroformates and alternative hydrolysis procedures.
    Acta pharmaceutica Suecica, 1974, Volume: 11, Issue:2

    Topics: Acylation; Amitriptyline; Chromatography, Gas; Diphenhydramine; Formates; Hydrocarbons, Brominated; Hydrocarbons, Chlorinated; Hydrolysis; Imipramine; Mass Spectrometry; Methadone; Methods; Methylamines; Propylamines; Time Factors

1974
Optimization of extraction and separation of narcotics from urine.
    Clinical biochemistry, 1974, Volume: 7, Issue:3

    Topics: Chromatography, Gas; Chromatography, Thin Layer; Cocaine; Codeine; Diphenhydramine; Evaluation Studies as Topic; Glucosidases; Humans; Indicators and Reagents; Meperidine; Methadone; Methaqualone; Methods; Morphine; Nalorphine; Narcotics; Nicotine; Pentazocine; Phenmetrazine; Time Factors

1974
Detection of methaqualone and its metabolites in urine.
    Journal of clinical pathology, 1969, Volume: 22, Issue:5

    Topics: Chlorpromazine; Chromatography, Thin Layer; Diphenhydramine; Humans; Methadone; Methaqualone; Methods

1969
Morphine dependent rats as a model for evaluating potential addiction liability of analgesic compounds.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 183, Issue:2

    Topics: Analgesics; Animals; Apomorphine; Azepines; Behavior, Animal; Codeine; Dextropropoxyphene; Diphenhydramine; Histamine; Humans; Meperidine; Meprobamate; Methadone; Methods; Morphine Dependence; Pentazocine; Pyrrolidines; Rats; Salicylates; Serotonin; Substance Withdrawal Syndrome

1970
Positive diphenhydramine interference in the EMIT-d.a.u. assay.
    Clinical chemistry, 1984, Volume: 30, Issue:8

    Topics: Diphenhydramine; False Positive Reactions; Humans; Immunoenzyme Techniques; Methadone; Substance-Related Disorders

1984
Use of headspace solid-phase microextraction (HS-SPME) in hair analysis for organic compounds.
    Forensic science international, 2000, Jan-10, Volume: 107, Issue:1-3

    Topics: Antidepressive Agents, Tricyclic; Cannabinoids; Chlormethiazole; Diphenhydramine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Lidocaine; Methadone; Nicotine; Poisoning; Sensitivity and Specificity; Solvents; Substance Abuse Detection; Tramadol

2000
AN ATTEMPT TO DEMONSTRATE CEILING EFFICACY OF ANALGESICS IN RATS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jan-01, Volume: 147

    Topics: Aminopyrine; Amphetamine; Amphetamines; Analgesics; Aspirin; Barbiturates; Chlordiazepoxide; Chlorpromazine; Codeine; Dextropropoxyphene; Diphenhydramine; Meperidine; Meprobamate; Methadone; Morphine; Pharmacology; Phenobarbital; Rats; Rectum; Research; Toxicology

1964
Methadone mouthwash for the management of oral ulcer pain.
    Journal of pain and symptom management, 2004, Volume: 27, Issue:5

    Topics: Administration, Oral; Aged; Analgesics, Opioid; Dexamethasone; Diphenhydramine; Drug Combinations; Facial Pain; Humans; Male; Methadone; Mouthwashes; Nystatin; Oral Ulcer; Tetracycline; Treatment Outcome

2004
Methadone toxicity fatalities: a review of medical examiner cases in a large metropolitan area.
    Journal of forensic sciences, 2007, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Antidepressive Agents; Benzodiazepines; Cannabinoids; Coroners and Medical Examiners; Diphenhydramine; Drug Prescriptions; Drug Tolerance; Female; Forensic Toxicology; Histamine H1 Antagonists; Humans; Kentucky; Male; Methadone; Middle Aged; Narcotics; Poisoning; Promethazine; Retrospective Studies; Substance-Related Disorders; Suicide

2007
Liability of addiction to 6-dimethylamino-4-4-diphenyl-3-heptanone (methadon, amidone or 10820) in man; experimental addiction to methadon.
    Archives of internal medicine (Chicago, Ill. : 1908), 1948, Volume: 82, Issue:4

    Topics: Behavior, Addictive; Biphenyl Compounds; Diphenhydramine; Ketones; Methadone

1948
Comparative investigations in to the analgesic effects of morphine and d, 1-6-dimethylamino-4,4-diphenyl-3-heptanone hydrochloride.
    Acta pharmacologica et toxicologica, 1949, Volume: 5, Issue:1

    Topics: Analgesics; Biphenyl Compounds; Diphenhydramine; Humans; Ketones; Methadone; Morphine

1949
A comparison of side actions and analgesic effects of morphine, amidone, (4-4-diphenyl-6-dimethylamino-heptanone-3) and its isomers in man.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Analgesics; Biphenyl Compounds; Diphenhydramine; Isomerism; Ketones; Methadone; Morphine; Morphine Derivatives

1948
Pharmacologic observations on 1,1-diphenyl-1 (dimethyl-aminoisopropyl)-butanone-2.
    Federation proceedings, 1947, Volume: 6, Issue:1

    Topics: Biphenyl Compounds; Butanones; Diphenhydramine; Humans; Methadone

1947
Pharmacology and the clinical use of dolophine (6-dimethyl-amino-4,4-diphenyl 3-heptanone hydrochloride).
    The American journal of medicine, 1947, Volume: 3, Issue:1

    Topics: Biphenyl Compounds; Diphenhydramine; Ketones; Methadone

1947
Rapid urine drug screens: diphenhydramine and methadone cross-reactivity.
    Pediatric emergency care, 2010, Volume: 26, Issue:9

    Topics: Analgesics, Opioid; Child; Diphenhydramine; Humans; Hypnotics and Sedatives; Immunoassay; Male; Methadone; Reproducibility of Results; Substance Abuse Detection; Substance-Related Disorders; Urinalysis

2010
Liquid-phase microextraction and desorption electrospray ionization mass spectrometry for identification and quantification of basic drugs in human urine.
    Rapid communications in mass spectrometry : RCM, 2012, Jan-30, Volume: 26, Issue:2

    Topics: Diphenhydramine; Humans; Limit of Detection; Linear Models; Liquid Phase Microextraction; Meperidine; Methadone; Nortriptyline; Pharmaceutical Preparations; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2012
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014
Contribution of in utero drug exposure when interpreting hair results in young children.
    Forensic science international, 2015, Volume: 249

    Topics: Amitriptyline; Bromazepam; Cannabinoids; Diazepam; Diphenhydramine; Female; Forensic Toxicology; Hair; Heroin; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Male; Maternal-Fetal Exchange; Methadone; Narcotics; Pregnancy; Substance-Related Disorders; Tramadol

2015
The becoming-methadone-body: on the onto-politics of health intervention translations.
    Sociology of health & illness, 2019, Volume: 41, Issue:8

    Topics: Analgesics, Opioid; Diphenhydramine; Humans; Hypnotics and Sedatives; Implementation Science; Interviews as Topic; Kyrgyzstan; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Politics; Prisoners; Substance Abuse, Intravenous

2019
QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with "Known Risk of Torsades de Pointes".
    Cardiovascular toxicology, 2022, Volume: 22, Issue:9

    Topics: Amitriptyline; Arrhythmias, Cardiac; Diphenhydramine; Electrocardiography; Flecainide; Humans; Long QT Syndrome; Methadone; Mirtazapine; Poison Control Centers; Retrospective Studies; Risk Factors; Tachycardia, Ventricular; Torsades de Pointes; Trazodone; Ventricular Fibrillation

2022