diphenhydramine and ketotifen

diphenhydramine has been researched along with ketotifen in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (27.78)	18.7374
1990's	4 (22.22)	18.2507
2000's	5 (27.78)	29.6817
2010's	3 (16.67)	24.3611
2020's	1 (5.56)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
DeLeo, JJ; Handley, DA; Havill, AM	1
Arimura, A; Inagaki, N; Koda, A; Miura, T; Mori, H; Nagai, H; Sakamoto, O	1
Chand, N; Diamantis, W; Pillar, J; Sofia, RD	2
Goto, S; Inagaki, N; Koda, A; Nagai, H	1
Awouters, F; Janssen, PA; Van den Broeck, WA; Wauquier, A	1
Chand, N; Diamantis, W; Perhach, JL; Pillar, J; Sofia, RD	1
Naclerio, RM	1
Hanai, N; Kusano, A; Masaki, S; Miki, I; Ohmori, K; Ohta, S; Otoshi, M; Sato, S	1
Fujii, Y; Harada, C; Hirai, T; Kamei, C; Tanaka, T	1
Hung, CR; Wang, PS	1
Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Rahman, A; Takechi, K	1
Honda, K; Ikeda, M; Ikeda-Sagara, M; Mohammad, S; Ozaki, T; Tsuno, S; Unno, K	1
Aritake, S; Enomoto, M; Hida, A; Katayose, Y; Kitamura, S; Mishima, K; Takahashi, K	1
Kanamitsu, K; Kusuhara, H; Nagaya, Y; Nozaki, Y; Sugiyama, Y	1
Bielory, L; Janeczko, P; Norris, MR	1

Reviews

2 review(s) available for diphenhydramine and ketotifen

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Assessment of receptor affinities of ophthalmic and systemic agents in dry eye disease. Current opinion in allergy and clinical immunology, 2021, 10-01, Volume: 21, Issue:5 Topics: Diphenhydramine; Dry Eye Syndromes; Histamine Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Ketotifen; Ophthalmic Solutions; Receptors, Histamine H3; Receptors, Muscarinic	2021

Trials

2 trial(s) available for diphenhydramine and ketotifen

Article	Year
The effect of antihistamines on the immediate allergic response: a comparative review. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1993, Volume: 108, Issue:6 Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Ketotifen; Mast Cells; Peptide Hydrolases; Phthalazines; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine	1993
Carryover effect on next-day sleepiness and psychomotor performance of nighttime administered antihistaminic drugs: a randomized controlled trial. Human psychopharmacology, 2012, Volume: 27, Issue:4 Topics: Blood-Brain Barrier; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Ketotifen; Male; Polysomnography; Psychomotor Performance; Pyridines; Sleep; Sleep Stages; Time Factors; Tissue Distribution; Young Adult; Zolpidem	2012

Article

Year

The effect of antihistamines on the immediate allergic response: a comparative review.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1993, Volume: 108, Issue:6

Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Ketotifen; Mast Cells; Peptide Hydrolases; Phthalazines; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine

1993

Carryover effect on next-day sleepiness and psychomotor performance of nighttime administered antihistaminic drugs: a randomized controlled trial.

Human psychopharmacology, 2012, Volume: 27, Issue:4

Topics: Blood-Brain Barrier; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Ketotifen; Male; Polysomnography; Psychomotor Performance; Pyridines; Sleep; Sleep Stages; Time Factors; Tissue Distribution; Young Adult; Zolpidem

2012

Other Studies

14 other study(ies) available for diphenhydramine and ketotifen

Article	Year
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Induction by aerosol allergen of sustained and nonspecific IgE-mediated airway hyperreactivity in the guinea pig. Agents and actions, 1992, Volume: 37, Issue:3-4 Topics: Acetylcholine; Aerosols; Allergens; Animals; Asthma; Bronchial Hyperreactivity; Diphenhydramine; Guinea Pigs; Histamine; Hormone Antagonists; Immunoglobulin E; Ketotifen; Organic Chemicals; Ovalbumin; Platelet Membrane Glycoproteins; Prednisolone; Pulmonary Eosinophilia; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Theophylline	1992
A method for evaluating anti-allergic drugs by simultaneously induced passive cutaneous anaphylaxis and mediator cutaneous reactions. International archives of allergy and applied immunology, 1990, Volume: 92, Issue:3 Topics: Albuterol; Animals; Diphenhydramine; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Isoproterenol; Ketotifen; Male; ortho-Aminobenzoates; Passive Cutaneous Anaphylaxis; Phenothiazines; Phthalazines; Rats; Rats, Inbred Strains; Skin Tests; Theophylline	1990
Inhibition of allergic histamine release by azelastine and selected antiallergic drugs from rabbit leukocytes. International archives of allergy and applied immunology, 1985, Volume: 77, Issue:4 Topics: Animals; Cromolyn Sodium; Diphenhydramine; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Ketotifen; Leukocytes; Male; Phthalazines; Pyridazines; Rabbits; Theophylline; Time Factors	1985
Inhibition of IgE-mediated allergic histamine release from rat peritoneal mast cells by azelastine and selected antiallergic drugs. Agents and actions, 1985, Volume: 16, Issue:5 Topics: Animals; Astemizole; Benzimidazoles; Diphenhydramine; Histamine Release; Hypersensitivity; Immunoglobulin E; Ketotifen; Male; Mast Cells; Ovalbumin; Phosphatidylserines; Phthalazines; Pyridazines; Rats; Rats, Inbred Strains; Theophylline	1985
Pharmacological characterization of mouse ear PCA. International archives of allergy and applied immunology, 1985, Volume: 78, Issue:2 Topics: Albuterol; Animals; Ascaris; Chlorpheniramine; Chromones; Cyproheptadine; Diphenhydramine; Dose-Response Relationship, Drug; Ear; Female; Histamine H1 Antagonists; Isoproterenol; Ketotifen; Male; Methysergide; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Passive Cutaneous Anaphylaxis; Serotonin Antagonists; Serum Albumin, Bovine; SRS-A; Theophylline; Tissue Extracts	1985
A comparison between astemizole and other antihistamines on sleep-wakefulness cycles in dogs. Neuropharmacology, 1981, Volume: 20, Issue:9 Topics: Animals; Astemizole; Benzimidazoles; Chlorpheniramine; Diphenhydramine; Dogs; Histamine H1 Antagonists; Ketotifen; Male; Periodicity; Pyrilamine; Sleep; Sleep Stages; Sleep, REM; Wakefulness	1981
Inhibition of calcium ionophore (A23187)-stimulated histamine release from rat peritoneal mast cells by azelastine: implications for its mode of action. European journal of pharmacology, 1983, Dec-23, Volume: 96, Issue:3-4 Topics: Animals; Ascitic Fluid; Calcimycin; Calcium; Diphenhydramine; Histamine H1 Antagonists; Histamine Release; Ketotifen; Male; Mast Cells; Phthalazines; Pyridazines; Rats; Rats, Inbred Strains	1983
Histamine enhanced the TNF-alpha-induced expression of E-selectin and ICAM-1 on vascular endothelial cells. Cellular immunology, 1996, Aug-01, Volume: 171, Issue:2 Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Dibenzoxepins; Diphenhydramine; Drug Interactions; E-Selectin; Endothelium, Vascular; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Intercellular Adhesion Molecule-1; Ketotifen; Olopatadine Hydrochloride; Pyrilamine; Ranitidine; Tumor Necrosis Factor-alpha; Umbilical Veins	1996
Epileptogenic activity induced by histamine H(1) antagonists in amygdala-kindled rats. Brain research, 2003, Nov-21, Volume: 991, Issue:1-2 Topics: Amygdala; Animals; Cetirizine; Diphenhydramine; Electroencephalography; Epilepsy; Histamine H1 Antagonists; Injections, Intraperitoneal; Ketotifen; Kindling, Neurologic; Loratadine; Male; Pyrilamine; Rats; Rats, Wistar	2003
Role of histamine and acid back-diffusion in modulation of gastric microvascular permeability and hemorrhagic ulcers in Salmonella typhimurium-infected rats. Life sciences, 2004, Mar-05, Volume: 74, Issue:16 Topics: Amine Oxidase (Copper-Containing); Animals; Capillary Permeability; Diphenhydramine; Disease Models, Animal; Gastric Acid; Gastric Mucosa; Histamine; Ketotifen; Peptic Ulcer Hemorrhage; Ranitidine; Rats; Rats, Wistar; Salmonella Infections, Animal; Salmonella typhimurium; Stomach Ulcer	2004
Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3 Topics: Administration, Oral; Animals; Animals, Suckling; Chlorpheniramine; Cyproheptadine; Dibenzazepines; Diphenhydramine; Dose-Response Relationship, Drug; Electroencephalography; Electroshock; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Rats; Rats, Wistar; Seizures; Terfenadine; Time Factors	2007
First and second generation H₁ histamine receptor antagonists produce different sleep-inducing profiles in rats. European journal of pharmacology, 2012, May-15, Volume: 683, Issue:1-3 Topics: Animals; Central Nervous System Stimulants; Circadian Rhythm; Diphenhydramine; Dose-Response Relationship, Drug; Drug Tolerance; Electroencephalography; Histamine H1 Antagonists; Hypnotics and Sedatives; Injections, Intraperitoneal; Ketotifen; Male; Nonprescription Drugs; Rats; Rats, Sprague-Dawley; Sleep; Sleep Stages; Sleep, REM; Wakefulness	2012
Quantitative prediction of histamine H1 receptor occupancy by the sedative and non-sedative antagonists in the human central nervous system based on systemic exposure and preclinical data. Drug metabolism and pharmacokinetics, 2017, Volume: 32, Issue:2 Topics: Animals; Brain; Central Nervous System; Diphenhydramine; Histamine H1 Antagonists; Humans; Ketotifen; Macaca fascicularis; Male; Mice; Mice, Inbred Strains; Olopatadine Hydrochloride; Piperidines; Positron-Emission Tomography; Pyridines; Receptors, Histamine H1; Time Factors	2017