diphenhydramine and ibuprofen

diphenhydramine has been researched along with ibuprofen in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19908 (19.05)18.7374
1990's7 (16.67)18.2507
2000's8 (19.05)29.6817
2010's17 (40.48)24.3611
2020's2 (4.76)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Caron, G; Ermondi, G1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Allen, JW; Black, PN; DiRusso, CC; Tu, B; Wase, N1
Blocher, CR; Byrne, K; Carey, PD; Michna, B; Sielaff, TD; Sugerman, HJ; Vasquez, A1
Blocher, CR; Byrne, K; Carey, PD; Hirsh, JI; Sielaff, TD; Sugerman, HJ; Tatum, JL; Vasquez, A1
Blocher, CR; Sielaff, TD; Sugerman, HJ; Tatum, JL1
Korthuis, RJ; Parker, JC; Taylor, AE; Townsley, MI1
Blocher, CR; Kellum, JM; Sielaff, TD; Sugerman, HJ; Tatum, JL1
Giri, SN; Scheinholtz, RM; Schwartz, LW; Siegel, DM1
Adams, T; Henriksen, N; Traber, DL; Traber, LD1
Carey, PD; Fowler, AA; Sugerman, HJ; Walsh, CJ; Windsor, AC1
Buttar, HS; Guest, I; Smith, S; Varma, DR1
Fisher, BJ; Fowler, AA; Leeper-Woodford, SK; Sugerman, HJ1
Hoffman, LM1
Byrne, K; Carey, D; Fisher, B; Fowler, AA; Leeper-Woodford, SK; Sugerman, HJ; Walsh, C1
SHUGAR, D; SZER, W1
BLAUG, SM; RICH, AG1
BANKER, GS; WOLFSON, BB1
Hu, C; Hu, X; Qu, J; Yang, M; Yuan, F1
Keating, N1
Mukkanti, K; Rao, DD; Sait, SS1
Gardinali, PR; Wang, J1
Burks, AW; Land, MH; Piehl, MD1
Douroumis, D; Scoutaris, N; Snowden, M1
Diaz, JH1
Chopade, SA; Early, JT; Guo, Y; Hillmyer, MA; Lodge, TP; Sun, CC; Tang, B; Wang, C; Wang, E1
Burnham, RI; Delva-Clark, H; Green, JL; Paul, IM; Reynolds, KM1
Azad, MA; Brancazio, D; Eccles, ME; Grela, E; Hammersmith, G; Klee, DM; Myerson, AS; Osorio, JG; Rapp, K; Sloan, R; Wang, A1
Hammad, SF; Saad Radwan, A; Salim, MM1
Atabaki, AH; Burgner, C; Herrington, WF; Jayaraman, V; Ram, RJ1

Reviews

2 review(s) available for diphenhydramine and ibuprofen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

40 other study(ies) available for diphenhydramine and ibuprofen

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae.
    Plant physiology, 2017, Volume: 174, Issue:4

    Topics: Biosynthetic Pathways; Chlamydomonas reinhardtii; Chlorophyta; Gas Chromatography-Mass Spectrometry; High-Throughput Screening Assays; Lipid Metabolism; Lipids; Metabolome; Metabolomics; Multivariate Analysis; Photosynthesis; Pigments, Biological; Plant Proteins; Starch

2017
Increased survival time after delayed histamine and prostaglandin blockade in a porcine model of severe sepsis-induced lung injury.
    Critical care medicine, 1990, Volume: 18, Issue:3

    Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Extravascular Lung Water; Hemodynamics; Histamine Antagonists; Ibuprofen; Prostaglandin Antagonists; Pseudomonas Infections; Respiratory Distress Syndrome; Shock, Septic; Swine

1990
Ranitidine compared to cimetidine in multiagent pharmacological treatment of porcine Pseudomonas ARDS.
    Circulatory shock, 1990, Volume: 30, Issue:2

    Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Pseudomonas Infections; Ranitidine; Respiratory Distress Syndrome; Respiratory Function Tests; Shock, Septic; Swine

1990
Successful treatment of adult respiratory distress syndrome by histamine and prostaglandin blockade in a porcine Pseudomonas model.
    Surgery, 1987, Volume: 102, Issue:2

    Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Ketanserin; Methylprednisolone; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Distress Syndrome; Swine

1987
Alterations in hemodynamics and Kf,c during lung mass resection.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:6

    Topics: Animals; Blood Pressure; Capillaries; Compliance; Diphenhydramine; Dogs; Filtration; Hemodynamics; Ibuprofen; In Vitro Techniques; Lung; Models, Biological; Perfusion; Pressure; Pulmonary Circulation; Vascular Resistance

1987
Treatment of porcine Pseudomonas ARDS with combination drug therapy.
    The Journal of trauma, 1987, Volume: 27, Issue:12

    Topics: Animals; Blood Pressure; Capillary Permeability; Cardiac Output; Cimetidine; Diphenhydramine; Drug Combinations; Drug Therapy, Combination; Extracellular Space; Ibuprofen; Ketanserin; Lung; Methylprednisolone; Pseudomonas Infections; Respiratory Distress Syndrome; Serotonin; Swine

1987
Characteristics and effect of antiinflammatory drugs on adriamycin-induced inflammation in the mouse paw.
    Inflammation, 1980, Volume: 4, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Capillary Permeability; Diphenhydramine; Doxorubicin; Fenclonine; Hydrocortisone; Ibuprofen; Indomethacin; Inflammation; Male; Metiamide; Mice; Time Factors

1980
Ibuprofen and diphenhydramine reduce the lung lesion of endotoxemia in sheep.
    The Journal of trauma, 1984, Volume: 24, Issue:9

    Topics: Animals; Blood Pressure; Blood Proteins; Cardiac Output; Diphenhydramine; Endotoxins; Female; Hematocrit; Ibuprofen; Leukocyte Count; Lung; Lymph; Proteins; Pulmonary Circulation; Sheep

1984
Multi-agent therapy in the treatment of sepsis-induced microvascular injury.
    The British journal of surgery, 1994, Volume: 81, Issue:12

    Topics: Animals; Cell Membrane Permeability; Cimetidine; Diphenhydramine; Hemodynamics; Hypochlorous Acid; Ibuprofen; Microcirculation; Neutrophils; Pulmonary Alveoli; Sepsis; Superoxides; Swine; Vascular Diseases

1994
Evaluation of the rat embryo culture system as a predictive test for human teratogens.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Captopril; Diphenhydramine; DNA; Embryo, Mammalian; False Negative Reactions; False Positive Reactions; Female; Humans; Ibuprofen; Neural Tube Defects; Organ Culture Techniques; Pregnancy; Rats; Teratogens; Valproic Acid

1994
Pharmacologic reduction in tumor necrosis factor activity of pulmonary alveolar macrophages.
    American journal of respiratory cell and molecular biology, 1993, Volume: 8, Issue:2

    Topics: Animals; Cells, Cultured; Cimetidine; Cyclooxygenase Inhibitors; Diphenhydramine; Histamine; Histamine H2 Antagonists; Ibuprofen; Lipopolysaccharides; Macrophages, Alveolar; Mice; Swine; Tumor Necrosis Factor-alpha

1993
Migraine.
    The Journal of family practice, 1993, Volume: 37, Issue:3

    Topics: Acetaminophen; Adult; Aspirin; Child; Diphenhydramine; Histamine H1 Antagonists; Humans; Ibuprofen; Migraine Disorders

1993
Histamine receptor antagonists, cyclooxygenase blockade, and tumor necrosis factor during acute septic insult.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:2

    Topics: Animals; Bacteremia; Blood Pressure; Cardiac Output; Cimetidine; Cyclooxygenase Inhibitors; Diphenhydramine; Disease Models, Animal; Drug Therapy, Combination; Histamine Antagonists; Hypertension, Pulmonary; Ibuprofen; Pseudomonas Infections; Swine; Tumor Necrosis Factor-alpha

1998
Preparation of poly-5-fluorouridylic acid and the properties of halogenated poly-uridylic acids and their complexes with poly-adenylic acid.
    Acta biochimica Polonica, 1963, Volume: 10

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Ketanserin; Methylprednisolone; Uracil Nucleotides; Uridine Monophosphate

1963
INTERACTION BETWEEN POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE AND CERTAIN PHARMACEUTICALS IN AQUEOUS SOLUTION.
    Journal of pharmaceutical sciences, 1965, Volume: 54

    Topics: Aspirin; Barbiturates; Benzoates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Indoles; Ketanserin; Macromolecular Substances; Methylprednisolone; Oxazoles; Oxazolidinones; Polymers; Research; Salicylic Acid; Sulfonamides; Xanthines

1965
SOLUBILIZATION AND EVALUATION OF POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE BARBITURATE SYSTEMS.
    Journal of pharmaceutical sciences, 1965, Volume: 54

    Topics: Barbiturates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Ketanserin; Methylprednisolone; Oxazoles; Oxazolidinones; Phenobarbital; Povidone; Research; Solubility

1965
Degradation of selected pharmaceuticals in aqueous solution with UV and UV/H(2)O(2).
    Water research, 2009, Volume: 43, Issue:6

    Topics: Antipyrine; Biodegradation, Environmental; Diphenhydramine; Hydrogen Peroxide; Ibuprofen; Kinetics; Oxidation-Reduction; Pesticide Residues; Phenytoin; Photochemistry; Photolysis; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical

2009
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Costs; Drug Therapy; Emergencies; Expectorants; First Aid; Glycerol; Guaifenesin; Histamine Antagonists; Honey; Humans; Hypersensitivity; Ibuprofen; Influenza Vaccines; Influenza, Human; Loratadine; Nonprescription Drugs; Oxymetazoline; Pharyngitis; Propiophenones; Pseudoephedrine; Rhinitis; Sodium Chloride

2009
By the way, doctor. I take ibuprofen p.m. on occasion--maybe once a month or so--to help me get to sleep. It seems to work. Is that okay?
    Harvard health letter, 2010, Volume: 35, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Drug Combinations; Humans; Hypnotics and Sedatives; Ibuprofen; Sleep

2010
Development and validation of an UPLC method for rapid determination of ibuprofen and diphenhydramine citrate in the presence of impurities in combined dosage form.
    Journal of chromatographic science, 2011, Volume: 49, Issue:4

    Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Diphenhydramine; Drug Combinations; Drug Contamination; Drug Stability; Ibuprofen; Least-Squares Analysis; Reproducibility of Results; Sensitivity and Specificity

2011
Uptake and depuration of pharmaceuticals in reclaimed water by mosquito fish (Gambusia holbrooki): a worst-case, multiple-exposure scenario.
    Environmental toxicology and chemistry, 2013, Volume: 32, Issue:8

    Topics: Animals; Caffeine; Carbamazepine; Cyprinodontiformes; Diphenhydramine; Fresh Water; Ibuprofen; Pharmaceutical Preparations; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical

2013
Near fatal anaphylaxis from orally administered gelatin capsule.
    The journal of allergy and clinical immunology. In practice, 2013, Volume: 1, Issue:1

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Anaphylaxis; Anti-Allergic Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Child; Diphenhydramine; Epinephrine; Famotidine; Female; Follow-Up Studies; Gelatin; Histamine H2 Antagonists; Humans; Ibuprofen; Prednisone; Treatment Outcome

2013
Taste masked thin films printed by jet dispensing.
    International journal of pharmaceutics, 2015, Oct-30, Volume: 494, Issue:2

    Topics: Administration, Oral; Cetirizine; Computer Systems; Diphenhydramine; Drug Delivery Systems; Humans; Ibuprofen; Taste; Technology, Pharmaceutical

2015
Hypersensitivity Reaction to Yellow Jacket Sting in a Previously Nonallergic Patient Taking an Angiotensin Receptor Blocker.
    Wilderness & environmental medicine, 2017, Volume: 28, Issue:2

    Topics: Aged; Angiotensin Receptor Antagonists; Animals; Anti-Allergic Agents; Diphenhydramine; Edema; Humans; Hypersensitivity; Ibuprofen; Insect Bites and Stings; Losartan; Male; Wasps

2017
Preparation, Characterization, and Formulation Development of Drug-Drug Protic Ionic Liquids of Diphenhydramine with Ibuprofen and Naproxen.
    Molecular pharmaceutics, 2018, 09-04, Volume: 15, Issue:9

    Topics: Diphenhydramine; Drug Carriers; Ibuprofen; Ionic Liquids; Magnetic Resonance Spectroscopy; Naproxen

2018
Flow Restrictors and Reduction of Accidental Ingestions of Over-the-Counter Medications.
    American journal of preventive medicine, 2019, Volume: 56, Issue:6

    Topics: Accidents; Acetaminophen; Age Factors; Antitussive Agents; Child, Preschool; Diphenhydramine; Drug Overdose; Drug Packaging; Female; Humans; Ibuprofen; Infant; Male; Nonprescription Drugs; Poison Control Centers; Seasons; United States

2019
On-Demand Manufacturing of Direct Compressible Tablets: Can Formulation Be Simplified?
    Pharmaceutical research, 2019, Oct-24, Volume: 36, Issue:12

    Topics: Ciprofloxacin; Diazepam; Diphenhydramine; Doxycycline; Drug Compounding; Drug Liberation; Excipients; Ibuprofen; Particle Size; Powders; Solubility; Solvents; Tablets

2019
Synchronous spectrofluorometric methods for simultaneous determination of diphenhydramine and ibuprofen or phenylephrine in combined pharmaceutical preparations.
    Luminescence : the journal of biological and chemical luminescence, 2020, Volume: 35, Issue:4

    Topics: Calibration; Diphenhydramine; Ibuprofen; Molecular Structure; Phenylephrine; Spectrometry, Fluorescence

2020
Low-power swept-source Raman spectroscopy.
    Optics express, 2021, Aug-02, Volume: 29, Issue:16

    Topics: Acetaminophen; Alcoholic Beverages; Diphenhydramine; Equipment Design; Humans; Ibuprofen; Lasers; Lenses; Methanol; Nutrients; Optical Devices; Spectrum Analysis, Raman; Toluene; Vegetables

2021