diphenhydramine and gabapentin

diphenhydramine has been researched along with gabapentin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (46.15)29.6817
2010's6 (46.15)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Choi, Y; Raymer, BK1
Courtade, D; Fiess, RN; Holmes, SA; Loubser, PG; Rintala, DH; Tastard, LV1
Backonja, M; Froman, S; Ho, TW; Leibensperger, H; Ma, J; Polydefkis, M1
Duntley, SP; Lucey, BP; Noetzel, MJ1
Jayawardena, S; Kay, GG; Rosenberg, RP; Schwartz, HI; Wingertzahn, MA1
Burton, S; Colwell, E; Conboy, G; Hagen, C; Jang, HY; Murphy, N; Parent, JM; Rist, PM1
Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H1

Reviews

2 review(s) available for diphenhydramine and gabapentin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Sleep modulating agents.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Animals; Humans; Sleep; Sleep Aids, Pharmaceutical; Sleep Wake Disorders; Wakefulness-Promoting Agents

2019

Trials

3 trial(s) available for diphenhydramine and gabapentin

ArticleYear
Comparison of the effectiveness of amitriptyline and gabapentin on chronic neuropathic pain in persons with spinal cord injury.
    Archives of physical medicine and rehabilitation, 2007, Volume: 88, Issue:12

    Topics: Adult; Aged; Amines; Amitriptyline; Analgesics; Analysis of Variance; Antidepressive Agents, Tricyclic; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diphenhydramine; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Histamine H1 Antagonists; Humans; Male; Middle Aged; Mononeuropathies; Pain; Pain Measurement; Spinal Cord Injuries

2007
Efficient assessment of neuropathic pain drugs in patients with small fiber sensory neuropathies.
    Pain, 2009, Volume: 141, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diphenhydramine; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neuralgia; Pain Measurement; Pain Threshold; Peripheral Nervous System Diseases; Single-Blind Method; Sleep Wake Disorders; Tramadol; Young Adult

2009
Next-day residual effects of gabapentin, diphenhydramine, and triazolam on simulated driving performance in healthy volunteers: a phase 3, randomized, double-blind, placebo-controlled, crossover trial.
    Human psychopharmacology, 2016, Volume: 31, Issue:3

    Topics: Adult; Amines; Analgesics; Anti-Anxiety Agents; Automobile Driving; Cognition; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diphenhydramine; Double-Blind Method; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Middle Aged; Sleep Stages; Time Factors; Triazolam

2016

Other Studies

8 other study(ies) available for diphenhydramine and gabapentin

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Paroxysmal arousals and myoclonic movements associated with interictal epileptiform discharges in NREM and REM sleep.
    Clinical neurology and neurosurgery, 2011, Volume: 113, Issue:5

    Topics: Adolescent; Amines; Antiparkinson Agents; Arousal; Chromosome Disorders; Chromosome Inversion; Chromosomes, Human, Pair 9; Chromosomes, Human, X; Cyclohexanecarboxylic Acids; Diphenhydramine; Electroencephalography; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Intellectual Disability; Myoclonus; Polysomnography; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Sleep, REM

2011
Paradoxical vestibular syndrome in a dog from western Newfoundland infected with French heartworm
    The Canadian veterinary journal = La revue veterinaire canadienne, 2016, Volume: 57, Issue:12

    Topics: Amines; Analgesics; Angiostrongylus; Animals; Anthelmintics; Cyclohexanecarboxylic Acids; Dexamethasone; Diphenhydramine; Dog Diseases; Dogs; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Immunosuppressive Agents; Macrolides; Male; Newfoundland and Labrador; Strongylida Infections; Vestibular Diseases

2016
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:5

    Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine

2021