diphenhydramine and fexofenadine

diphenhydramine has been researched along with fexofenadine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.55)18.2507
2000's11 (50.00)29.6817
2010's9 (40.91)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S1
Sen, S; Sinha, N1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Rankovic, Z1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baker, TW; Bloomfield, JR; Brown, TL; Grant, AR; Layton, TA; McKenzie, DR; Watson, GS; Weiler, JM; Woodworth, GG1
Hennessy, S; Strom, BL1
Brookhuis, KA; de Waard, D1
Demonaco, HJ; Dudley, J; Lee, TH1
Angello, JT; Druce, HM1
Gu, X; Silver, NA; Simons, FE; Simons, KJ1
Austin, M; Bower, EA; Meeves, S; Moore, JL; Moss, M; Selby, KA1
Flores, J; Mansfield, L; Meeves, SG; Mendoza, C1
Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Rahman, A; Takechi, K1
Casale, TB; Jones, DH; Romero, FA1
Codreanu, I; Dasanu, CA; Divgi, C; Weinstein, GS1
Hayashi, M; Hirohata, A; Katayama, I; Murota, H; Tani, M; Yamaoka, T1
Grobosch, T; Hiraoka, K; Inami, A; Komamura, H; Matsuda, R; Maurer, M; Miyake, M; Takeda, K; Tashiro, M; Yamada, Y; Yanai, K1
Bosma, R; Labeaga, L; Leurs, R; van den Bor, J; Vischer, HF1
Guidon, AC; Long, AA; Slawski, BR; Suh, J1
Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H1

Reviews

2 review(s) available for diphenhydramine and fexofenadine

ArticleYear
CNS drug design: balancing physicochemical properties for optimal brain exposure.
    Journal of medicinal chemistry, 2015, Mar-26, Volume: 58, Issue:6

    Topics: Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Central Nervous System Agents; Drug Design; Humans; Models, Molecular; Permeability

2015
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

6 trial(s) available for diphenhydramine and fexofenadine

ArticleYear
Effects of fexofenadine, diphenhydramine, and alcohol on driving performance. A randomized, placebo-controlled trial in the Iowa driving simulator.
    Annals of internal medicine, 2000, Mar-07, Volume: 132, Issue:5

    Topics: Adult; Automobile Driving; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Ethanol; Female; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Iowa; Male; Markov Chains; Middle Aged; Monte Carlo Method; Placebos; Rhinitis, Allergic, Seasonal; Sleep Stages; Terfenadine

2000
Skin concentrations of H1-receptor antagonists.
    The Journal of allergy and clinical immunology, 2001, Volume: 107, Issue:3

    Topics: Adult; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hypersensitivity, Delayed; Male; Prospective Studies; Skin; Terfenadine

2001
The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel.
    Aviation, space, and environmental medicine, 2003, Volume: 74, Issue:2

    Topics: Administration, Oral; Adult; Aerospace Medicine; Attention; Cognition; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Placebos; Reaction Time; Sleep Stages; Terfenadine

2003
Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA).
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:5

    Topics: Adolescent; Adult; Attention; Cognition; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Reaction Time; Sleep Stages; Terfenadine

2003
Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2008, Volume: 100, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Child; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity, Immediate; Injections, Intramuscular; Male; Middle Aged; Skin Tests; Terfenadine; Time Factors; Treatment Outcome

2008
A simulated car-driving study on the effects of acute administration of levocetirizine, fexofenadine, and diphenhydramine in healthy Japanese volunteers.
    Human psychopharmacology, 2016, Volume: 31, Issue:3

    Topics: Adult; Asian People; Automobile Driving; Cetirizine; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Psychomotor Performance; Reaction Time; Terfenadine; Young Adult

2016

Other Studies

14 other study(ies) available for diphenhydramine and fexofenadine

ArticleYear
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water

1998
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Nonsedating antihistamines should be preferred over sedating antihistamines in patients who drive.
    Annals of internal medicine, 2000, Mar-07, Volume: 132, Issue:5

    Topics: Automobile Driving; Diphenhydramine; Ethanol; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Terfenadine

2000
Drug effects on driving performance.
    Annals of internal medicine, 2000, Oct-17, Volume: 133, Issue:8

    Topics: Automobile Driving; Diphenhydramine; Ethanol; Histamine H1 Antagonists; Humans; Research Design; Terfenadine

2000
Drug effects on driving performance.
    Annals of internal medicine, 2000, Oct-17, Volume: 133, Issue:8

    Topics: Automobile Driving; Diphenhydramine; Ethanol; Histamine H1 Antagonists; Humans; Research Design; Terfenadine

2000
Drug effects on driving performance.
    Annals of internal medicine, 2000, Oct-17, Volume: 133, Issue:8

    Topics: Automobile Driving; Diphenhydramine; Ethanol; Histamine H1 Antagonists; Humans; Research Design; Terfenadine

2000
Newer antihistamines.
    The Medical letter on drugs and therapeutics, 2001, Apr-30, Volume: 43, Issue:1103

    Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Somnambulism; Terfenadine

2001
Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3

    Topics: Administration, Oral; Animals; Animals, Suckling; Chlorpheniramine; Cyproheptadine; Dibenzazepines; Diphenhydramine; Dose-Response Relationship, Drug; Electroencephalography; Electroshock; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Rats; Rats, Wistar; Seizures; Terfenadine; Time Factors

2007
Fluorodeoxyglucose-induced allergic reaction: a case report.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:1

    Topics: Anti-Allergic Agents; Anti-Inflammatory Agents; Carcinoma, Squamous Cell; Diphenhydramine; Drug Hypersensitivity; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Male; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Prednisone; Pyriform Sinus; Radiopharmaceuticals; Secondary Prevention; Squamous Cell Carcinoma of Head and Neck; Terfenadine; Tomography, X-Ray Computed; Treatment Outcome

2013
Unique case of postural cholinergic urticaria induced by a standing position.
    Clinical and experimental dermatology, 2016, Volume: 41, Issue:4

    Topics: Acetylcholine; Adolescent; Diphenhydramine; Humans; Male; Posture; Terfenadine; Urticaria

2016
The long duration of action of the second generation antihistamine bilastine coincides with its long residence time at the histamine H
    European journal of pharmacology, 2018, Nov-05, Volume: 838

    Topics: Benzimidazoles; Diphenhydramine; HeLa Cells; Histamine H1 Antagonists, Non-Sedating; Humans; Piperidines; Receptors, Histamine H1; Terfenadine; Time Factors

2018
Rituximab desensitization in two patients with muscle-specific kinase myasthenia gravis.
    Muscle & nerve, 2019, Volume: 60, Issue:5

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Autoantibodies; Desensitization, Immunologic; Diphenhydramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists; Humans; Hydrocortisone; Immunologic Factors; Infusions, Intravenous; Myasthenia Gravis; Premedication; Receptor Protein-Tyrosine Kinases; Receptors, Cholinergic; Rituximab; Terfenadine

2019
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:5

    Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine

2021