diphenhydramine and dimenhydrinate

diphenhydramine has been researched along with dimenhydrinate in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199017 (53.13)18.7374
1990's3 (9.38)18.2507
2000's6 (18.75)29.6817
2010's6 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gralla, EJ; Hayden, DW; Mattsson, JL; Sabo, JP; Yochmowitz, MG1
Mason, WD; Walters-Thompson, KM1
Greenblatt, DJ; Harmatz, JS; Luna, BG; Scavone, JM; von Moltke, L1
Gong, HL; Wang, GF; Wu, YT1
Jaju, BP; Wang, SC1
Gault, FP; Yules, RB1
Aschan, G1
Andriano, JP; Giannini, AJ; Gregg, LO1
Kurnatowski, P1
Cantwell, FF; Fossey, L1
Aderjan, R; Bösche, J; Schmidt, G1
McDonnell, KP; Winn, RE1
Midroni, G; Moulton, R1
Jackman, SL; Olmstead, MC; Paine, TA1
Beninger, RJ; Halpert, AG; Olmstead, MC1
Dragoni, S; Frosini, M; Fusi, F; Sgaragli, G; Valoti, M1
BORISON, HL; BRIZZEE, KR; SATA, E; SCHMIDT, CD1
CONWAY, H; JEROME, AP; STARK, RB1
BRUCKNER, G1
PEARSON, RG1
CRISWICK, VG; DOBKIN, AB1
KARAS, JS; STANBURY, JB1
FOLLIS, G; LING, JT; MARSHALL, TR; RUSSELL, M1
WRIGHT, WL1
Booze, LL; Caravati, EM; Christianson, G; Chyka, PA; Erdman, AR; Keyes, DC; Manoguerra, AS; Nelson, LS; Olson, KR; Scharman, EJ; Troutman, WG; Wax, PM; Woolf, AD1
Carius, R; Kiess, W; Kostev, K; Pfeil, N; Schröder, H; Uhlig, HH; Uhlig, U1
Jang, CG; Lee, SY; Nguyen, TL; Oh, S; Yang, CH; You, IJ1
Alfaya Arias, T; Iglesias Aranzazu, M; Lombardero Vega, M; Mur Gimeno, P; Sastre, B1
Goez, H; Huntsman, RJ; Sawicka, KM1
Bäumer, W; Ehling, S; Papich, MG1

Reviews

1 review(s) available for diphenhydramine and dimenhydrinate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for diphenhydramine and dimenhydrinate

ArticleYear
Diphenhydramine kinetics following intravenous, oral, and sublingual dimenhydrinate administration.
    Biopharmaceutics & drug disposition, 1990, Volume: 11, Issue:3

    Topics: Administration, Oral; Administration, Sublingual; Adolescent; Adult; Biological Availability; Chromatography, Gas; Dimenhydrinate; Diphenhydramine; Female; Half-Life; Humans; Injections, Intravenous; Male; Middle Aged; Random Allocation

1990
Habituation to repeated rotatory stimuli (cupulometry) and the effect of antinausea drugs and alcohol on the results.
    Acta oto-laryngologica, 1967, Volume: 64, Issue:2

    Topics: Aerospace Medicine; Alcoholic Intoxication; Chlorpheniramine; Clinical Trials as Topic; Dimenhydrinate; Diphenhydramine; Humans; Nausea; Placebos; Rotation; Scopolamine; Vestibular Function Tests

1967
Pharmacokinetics of diphenhydramine in healthy volunteers with a dimenhydrinate 25 mg chewing gum formulation.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:5

    Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Chewing Gum; Chromatography, Gas; Dimenhydrinate; Diphenhydramine; Dose-Response Relationship, Drug; Female; Half-Life; Histamine H1 Antagonists; Humans; Male; Metabolic Clearance Rate

2003

Other Studies

28 other study(ies) available for diphenhydramine and dimenhydrinate

ArticleYear
The effect of selected drugs on first-stage radioemesis in beagle dogs.
    Radiation research, 1979, Volume: 78, Issue:2

    Topics: Amifostine; Amphetamine; Animals; Antiemetics; Body Weight; Chlorpromazine; Dimenhydrinate; Diphenhydramine; Dogs; Drug Combinations; Perphenazine; Phenytoin; Radiation Injuries, Experimental; Scopolamine; Vomiting; X-Rays

1979
Method for the determination of diphenhydramine in rabbit whole blood by high-performance liquid chromatography (HPLC) with ultraviolet (UV) detection in conjunction with gas chromatography (GC) with mass selective detection (MSD).
    Pharmaceutical research, 1992, Volume: 9, Issue:7

    Topics: Animals; Chromatography, High Pressure Liquid; Dimenhydrinate; Diphenhydramine; Gas Chromatography-Mass Spectrometry; Rabbits; Spectrophotometry, Ultraviolet

1992
[Determination of dimenhydrinate by computer-aided convolution curve method].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:10

    Topics: Dimenhydrinate; Diphenhydramine; Drug Combinations; Electronic Data Processing; Tablets; Theophylline

1988
Effects of diphenhydramine and dimenhydrinate on vestibular neuronal activity of cat: a search for the locus of their antimotion sickness action.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:3

    Topics: Animals; Cats; Dimenhydrinate; Diphenhydramine; Electric Stimulation; Evoked Potentials; Motion Sickness; Synaptic Transmission; Time Factors; Vestibular Nerve; Vestibular Nuclei

1971
Effect of drugs on after-nystagmus induced by lateral vestibular nucleus stimulation.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1967, Volume: 85, Issue:3

    Topics: Animals; Cats; Chlorpromazine; Cyclizine; Dimenhydrinate; Diphenhydramine; Electric Stimulation; Hydroxyzine; Lidocaine; Meclizine; Nystagmus, Pathologic; Pentobarbital; Phenothiazines; Piperazines; Prochlorperazine; Promethazine; Tripelennamine; Vestibular Nuclei

1967
P's and blues: potentiation of propoxyphene withdrawal by a variety of antihistamines.
    Journal of toxicology. Clinical toxicology, 1984, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Dextropropoxyphene; Dimenhydrinate; Diphenhydramine; Drug Synergism; Female; Histamine H1 Antagonists; Humans; Male; Substance Withdrawal Syndrome

1984
[In vitro antibacterial activity of drugs from the group of ethanolamine, phenothiazine and aminoalkyl derivatives with antihistaminic action].
    Acta poloniae pharmaceutica, 1984, Volume: 41, Issue:4

    Topics: Bacteria; Chlorpromazine; Clemastine; Dimenhydrinate; Diphenhydramine; Drug Resistance, Microbial; Ethanolamines; Histamine H1 Antagonists; In Vitro Techniques; Microbial Sensitivity Tests; Phenothiazines; Piperidines; Promethazine

1984
Simultaneous monitoring of both phases in the solvent extraction/flow injection analysis of Dramamine tablets.
    Analytical chemistry, 1983, Volume: 55, Issue:12

    Topics: Chemical Phenomena; Chemistry; Dimenhydrinate; Diphenhydramine; Solvents; Tablets; Theophylline

1983
[Poisoning by diphenhydramine--forensic-toxicologic interpretation of analytic results ].
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1982, Volume: 88, Issue:4

    Topics: Accidents, Traffic; Biotransformation; Dimenhydrinate; Diphenhydramine; Drug Combinations; Forensic Medicine; Half-Life; Humans; Metabolic Clearance Rate; Suicide, Attempted

1982
Fatality secondary to massive overdose of dimenhydrinate.
    Annals of emergency medicine, 1993, Volume: 22, Issue:9

    Topics: Adult; Arrhythmias, Cardiac; Cardiopulmonary Resuscitation; Charcoal; Colon; Dimenhydrinate; Diphenhydramine; Dopamine; Drug Overdose; Female; Humans; Infarction; Lidocaine; Lorazepam; Nonprescription Drugs; Phenytoin; Status Epilepticus; Suicide

1993
Radial entrapment neuropathy due to chronic injection-induced triceps fibrosis.
    Muscle & nerve, 2001, Volume: 24, Issue:1

    Topics: Adult; Chronic Disease; Diazepam; Dimenhydrinate; Diphenhydramine; Drug Therapy, Combination; Electrodiagnosis; Female; Fibrosis; Humans; Hydromorphone; Injections, Intramuscular; Male; Meperidine; Middle Aged; Muscle, Skeletal; Nerve Compression Syndromes; Neural Conduction; Radial Neuropathy; Reaction Time; Somatoform Disorders

2001
Cocaine-induced anxiety: alleviation by diazepam, but not buspirone, dimenhydrinate or diphenhydramine.
    Behavioural pharmacology, 2002, Volume: 13, Issue:7

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Buspirone; Cocaine; Conflict, Psychological; Diazepam; Dimenhydrinate; Diphenhydramine; Dose-Response Relationship, Drug; Exploratory Behavior; Injections, Intraperitoneal; Male; Maze Learning; Rats; Rats, Long-Evans; Substance Withdrawal Syndrome

2002
Dimenhydrinate produces a conditioned place preference in rats.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:1

    Topics: Animals; Conditioning, Operant; Dimenhydrinate; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Male; Motor Activity; Rats; Rats, Wistar; Theophylline

2003
Effect of dimenhydrinate and diphenhydramine on apomorphine-induced emesis in dogs and cats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1953, Volume: 82, Issue:3

    Topics: Animals; Apomorphine; Cats; Dimenhydrinate; Diphenhydramine; Dogs; Vomiting

1953
Observations on the development of circulation in skin grafts. VII. Effect of antihistaminic (Benadryl) on homologous skin grafts.
    Plastic and reconstructive surgery (1946), 1953, Volume: 12, Issue:2

    Topics: Biological Phenomena; Dimenhydrinate; Diphenhydramine; Humans; Physiological Phenomena; Skin; Skin Transplantation

1953
[Treatment of toxic vomiting with the antiemetic rodovan].
    Die Medizinische, 1957, Jul-13, Issue:27-28

    Topics: Antiemetics; Dimenhydrinate; Diphenhydramine; Humans; Vomiting; Xanthines

1957
A note on the psychomotor effects of diphenhydramine hydrochloride and dimenhydrinate.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1957, Volume: 46, Issue:11

    Topics: Dimenhydrinate; Diphenhydramine; Humans

1957
The antisialogogue effect of trimethobenzamide HC1 (Tigan), trimeprazine tartrate (Panectyl), diphenhydramine HC1 (Benadryl), dimenhydrinate (Gravol, Dramamine), and cyclizine lactate (Marzine, Marazine).
    Canadian Anaesthetists' Society journal, 1961, Volume: 8

    Topics: Anti-Allergic Agents; Antiemetics; Benzamides; Cyclizine; Dimenhydrinate; Diphenhydramine; Histamine H1 Antagonists; Humans; Lactates; Salivary Glands; Trimeprazine

1961
FATAL RADIATION SYNDROME FROM AN ACCIDENTAL NUCLEAR EXCURSION.
    The New England journal of medicine, 1965, Apr-15, Volume: 272

    Topics: Accidents; Accidents, Occupational; Angiotensins; Blood Cell Count; Blood Chemical Analysis; Bone Marrow Cells; Chloramphenicol; Dimenhydrinate; Diphenhydramine; Drug Therapy; Electrocardiography; Emergency Service, Hospital; Hemoglobinometry; Humans; Mannitol; Metaraminol; Methylprednisolone; Morphine; Neomycin; Norepinephrine; Radiation Injuries; Radiation Protection; Uranium

1965
PHARMACOLOGICAL INCOMPATIBILITY OF CONTRAST MEDIA WITH VARIOUS DRUGS AND AGENTS.
    Radiology, 1965, Volume: 84

    Topics: Chlorpheniramine; Contrast Media; Diatrizoate; Dimenhydrinate; Diphenhydramine; Drug Incompatibility; Histamine H1 Antagonists; Iodipamide; Iodopyracet; Iothalamic Acid; Pharmacology; Polystyrenes; Syringes

1965
Effectiveness of newer drugs in seasickness.
    United States Armed Forces medical journal, 1950, Volume: 1, Issue:5

    Topics: Dimenhydrinate; Diphenhydramine; Humans; Motion Sickness

1950
Diphenhydramine and dimenhydrinate poisoning: an evidence-based consensus guideline for out-of-hospital management.
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:3

    Topics: Age Factors; Ambulatory Care; Dimenhydrinate; Diphenhydramine; Dose-Response Relationship, Drug; Emergency Medical Services; Evidence-Based Medicine; Humans; Poisoning

2006
Antiemetic medications in children with presumed infectious gastroenteritis--pharmacoepidemiology in Europe and Northern America.
    The Journal of pediatrics, 2008, Volume: 153, Issue:5

    Topics: Antiemetics; Child; Child, Preschool; Dimenhydrinate; Diphenhydramine; Domperidone; Europe; Female; Gastroenteritis; Humans; Infant; Infant, Newborn; Male; North America; Ondansetron; Pharmacoepidemiology; Promethazine; Retrospective Studies

2008
Assessment of the rewarding effects of dimenhydrinate using the conditioned place preference paradigm in mice.
    Neuroscience letters, 2010, Feb-26, Volume: 471, Issue:1

    Topics: Animals; Choice Behavior; Cocaine; Conditioning, Psychological; Dimenhydrinate; Diphenhydramine; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Mice, Inbred ICR; Reward; Theophylline

2010
Anaphylactic shock caused by antihistamines.
    Journal of investigational allergology & clinical immunology, 2011, Volume: 21, Issue:4

    Topics: Administration, Oral; Allergens; Anaphylaxis; Antiemetics; Caffeine; Dimenhydrinate; Diphenhydramine; Drug Combinations; Female; Hand Dermatoses; Histamine Antagonists; Humans; Immunoglobulin E; Middle Aged; Nasal Polyps; Respiratory Hypersensitivity; Single-Blind Method; Skin Tests

2011
Diphenhydramine, dimenhydrinate: misuse.
    Prescrire international, 2015, Volume: 24, Issue:165

    Topics: Dimenhydrinate; Diphenhydramine; France; Histamine H1 Antagonists; Humans; Substance-Related Disorders

2015
Successful Treatment of Paroxysmal Movement Disorders of Infancy With Dimenhydrinate and Diphenhydramine.
    Pediatric neurology, 2016, Volume: 56

    Topics: Dimenhydrinate; Diphenhydramine; Electroencephalography; Histamine H1 Antagonists; Humans; Infant; Male; Movement Disorders

2016
Diphenhydramine pharmacokinetics after oral and intravenous administration of diphenhydramine and oral administration of dimenhydrinate to healthy dogs, and pharmacodynamic effect on histamine-induced wheal formation: a pilot study.
    Veterinary dermatology, 2019, Volume: 30, Issue:2

    Topics: Administration, Intravenous; Administration, Oral; Animals; Cross-Over Studies; Dimenhydrinate; Diphenhydramine; Dogs; Female; Half-Life; Histamine; Histamine Antagonists; Male; Pilot Projects; Theophylline; Urticaria

2019