diphenhydramine has been researched along with dextromethorphan in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (18.18) | 18.7374 |
| 1990's | 3 (6.82) | 18.2507 |
| 2000's | 16 (36.36) | 29.6817 |
| 2010's | 14 (31.82) | 24.3611 |
| 2020's | 3 (6.82) | 2.80 |
| Authors | Studies |
|---|---|
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Burgi, H; Cosnier, D; Duchêne-Marullaz, P; Rispat, G; Streichenberger, G | 1 |
| Matts, SG | 1 |
| Fabregas, JL; Margalet, A | 1 |
| Karttunen, P; Nuutinen, J; Saano, V; Silvasti, M; Virta, P | 1 |
| Bambagiotti-Alberti, M; Pinzauti, S; Vincieri, FF | 1 |
| Doyle, TD; Proctor, JB | 1 |
| Doyle, TD | 1 |
| Weippl, G | 1 |
| Diekema, DS; Robertson, WO; Warden, CR | 1 |
| Baird, TJ; Briscoe, RJ; Carl, KL; Gauvin, DV; Holloway, FA; Sannerud, CA; Vallett, M; Vanecek, SA | 1 |
| Gomez, MR; Martínez, LD; Olsina, RA; Silva, MF | 1 |
| Jun, JH; Schindler, CW; Thorndike, EB | 1 |
| Berlin, CM; Carlson, LC; Crowell, KR; Dilworth, DA; McMillan, HS; Paul, IM; Shaffer, ML; Yoder, KE | 1 |
| Bhatt-Mehta, V | 1 |
| Walburn, J | 1 |
| Skoner, DP | 1 |
| Chen, X; Chen, Y; Dong, Y; Hu, Z | 1 |
| Akkaramongkolporn, P; Kulvanich, P; Pathipvanich, M | 1 |
| Ali, MS; Ghori, M; Khatri, AR; Rafiuddin, S | 1 |
| La Tournous, SJ; Paul, IM; Shaffer, ML; Yoder, KE | 1 |
| Mozaffari-Khosravi, H; Mozayan, MR; Shadkam, MN | 1 |
| Carter, D; Gabardi, S; Martin, S; Roberts, K | 1 |
| Akkaramongkolporn, P; Ngawhirunpat, T; Nitanan, T; Opanasopit, P; Panomsuk, S; Rojanarata, T | 1 |
| Mullins, ME; Rengarajan, A | 1 |
| Beuhler, MC; Doyon, S; Klein-Schwartz, W; Lee, S | 1 |
| Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M | 1 |
| Meremikwu, MM; Oduwole, O; Oyo-Ita, A; Udoh, EE | 2 |
| Brew, J; Caparros-Wanderley, W; Dhar, S; Dicpinigaitis, PV; Gayle, Y; Johnson, A | 1 |
| Goyal, RN; Karpoormath, R; Patel, H; Patel, R; Thapliyal, N | 1 |
| Adhikari, S; Alexander, K; Boddu, SHS; Daftardar, S; Fratev, F; Rivera, M; Sirimulla, S | 1 |
| Banner, W; Bond, GR; Dart, RC; Green, JL; Kauffman, RE; Palmer, RB; Paul, IM; Rapp-Olsson, M; Reynolds, KM; Wang, GS | 2 |
| Banner, W; Bond, GR; Dart, RC; Delva-Clark, H; Green, JL; Halmo, LS; Kauffman, RE; Palmer, RB; Paul, IM; Rapp-Olsson, M; Reynolds, KM; Wang, GS | 1 |
5 review(s) available for diphenhydramine and dextromethorphan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Recommendations for the proper use of nonprescription cough suppressants and expectorants in solid-organ transplant recipients.
Topics: Antitussive Agents; Codeine; Contraindications; Dextromethorphan; Diphenhydramine; Drug Interactions; Drug Monitoring; Drug Utilization; Expectorants; Guaifenesin; Humans; Immunosuppressive Agents; Nonprescription Drugs; Organ Transplantation; Safety | 2011 |
Honey for acute cough in children.
Topics: Adolescent; Antitussive Agents; Apitherapy; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; Honey; Humans; Infant; Randomized Controlled Trials as Topic | 2014 |
A categorical review on electroanalytical determination of non-narcotic over-the-counter abused antitussive drugs.
Topics: Antitussive Agents; Dextromethorphan; Diphenhydramine; Electrochemical Techniques; Illicit Drugs; Nonprescription Drugs | 2015 |
Honey for acute cough in children.
Topics: Adolescent; Albuterol; Antitussive Agents; Apitherapy; Bromelains; Bronchodilator Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; Honey; Humans; Infant; Placebos; Randomized Controlled Trials as Topic | 2018 |
6 trial(s) available for diphenhydramine and dextromethorphan
| Article | Year |
|---|---|
A trial of Lotussin and linctus diphenhydramine in patients wth an irritant cough.
Topics: Ammonium Chloride; Antitussive Agents; Chloroform; Citrates; Clinical Trials as Topic; Cough; Dextromethorphan; Diphenhydramine; Drug Combinations; Drug Evaluation; Ephedrine; Guaifenesin; Humans; Menthol | 1977 |
Therapeutic approaches to the common cold in children.
Topics: Antitussive Agents; Child; Child, Preschool; Clinical Trials as Topic; Common Cold; Cyproheptadine; Dextromethorphan; Diphenhydramine; Double-Blind Method; Drug Combinations; Ephedrine; Expectorants; Histamine H1 Antagonists; Humans; Levorphanol; Pseudoephedrine | 1984 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; Double-Blind Method; Female; Humans; Male; Respiratory Tract Infections; Sleep Initiation and Maintenance Disorders; Sleep Stages | 2004 |
Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection.
Topics: Adolescent; Antitussive Agents; Child; Cough; Dextromethorphan; Diphenhydramine; Female; Humans; Male; Placebos; Respiratory Tract Infections; Treatment Outcome | 2006 |
A comparison of the effect of honey, dextromethorphan, and diphenhydramine on nightly cough and sleep quality in children and their parents.
Topics: Antitussive Agents; Apitherapy; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; Female; Honey; Humans; Male; Parents; Respiratory Tract Infections; Sleep; Time Factors | 2010 |
Inhibition of cough reflex sensitivity by diphenhydramine during acute viral respiratory tract infection.
Topics: Adult; Antitussive Agents; Capsaicin; Cough; Dextromethorphan; Diphenhydramine; Double-Blind Method; Female; Humans; Male; Reflex; Respiratory Tract Infections; Young Adult | 2015 |
33 other study(ies) available for diphenhydramine and dextromethorphan
| Article | Year |
|---|---|
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
General pharmacological properties of a new non-opiate antitussive: zipeprol (3024 CERM). I. Action on respiratory function and acute toxicity.
Topics: Administration, Oral; Anesthetics, Local; Animals; Antitussive Agents; Bronchi; Cats; Codeine; Cough; Dextromethorphan; Diphenhydramine; Dogs; Expectorants; Female; Guinea Pigs; Histamine H1 Antagonists; Humans; In Vitro Techniques; Injections, Intravenous; Lethal Dose 50; Male; Mice; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperazines; Rats; Respiration | 1976 |
American Academy of Pediatrics. Committee on Drugs. Use of codeine- and dextromethorphan-containing cough syrups in pediatrics.
Topics: Adolescent; Animals; Antitussive Agents; Child; Child, Preschool; Codeine; Cough; Dextromethorphan; Diphenhydramine; Drug Combinations; Drug Packaging; Humans; Infant; Levorphanol; Male; Narcotics; Pediatrics; Societies, Medical; United States | 1978 |
GLC trace analysis of dextromethorphan and bromhexine salts in pharmaceutical preparations.
Topics: Bromhexine; Chromatography, Gas; Dextromethorphan; Diphenhydramine; Levorphanol; Technology, Pharmaceutical | 1975 |
The effects of vadocaine, dextromethorphan, diphenhydramine and hydroxyzine on the ciliary beat frequency in rats in vitro.
Topics: Animals; Cilia; Dextromethorphan; Diphenhydramine; Hydroxyzine; Male; Mucociliary Clearance; Piperidines; Rats; Rats, Inbred Strains; Time Factors; Trachea | 1990 |
Simultaneous capillary gas chromatographic determination of guaifenesin, dextromethorphan and diphenhydramine in cough-cold syrup.
Topics: Chromatography, Gas; Dextromethorphan; Diphenhydramine; Drug Combinations; Expectorants; Guaifenesin; Levorphanol | 1987 |
Effects of solvent composition on the partition of amines: extraction of the free base.
Topics: Alkanes; Amines; Amphetamine; Brompheniramine; Chloroform; Chlorpheniramine; Codeine; Dextromethorphan; Diphenhydramine; Ions; Mathematics; Mescaline; Methamphetamine; Methylamines; Phenethylamines; Pheniramine; Quinine; Solubility; Water | 1972 |
Effects of solvent composition on the column partition chromatography of amines: computer-generated distribution maps.
Topics: Amines; Chlorides; Chloroform; Chlorpheniramine; Chromatography; Computers; Cyclizine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Hydrogen-Ion Concentration; Methods; Methylamines; Promethazine | 1971 |
Dystonic reaction associated with dextromethorphan ingestion in a toddler.
Topics: Antidotes; Antitussive Agents; Ataxia; Child, Preschool; Dextromethorphan; Diphenhydramine; Dystonia; Female; Humans; Nystagmus, Pathologic; Poisoning | 1997 |
The stimulus properties of two common over-the-counter drug mixtures: dextromethorphan + ephedrine and dextromethorphan + diphenhydramine.
Topics: Adrenergic Agents; Animals; Antitussive Agents; Dextromethorphan; Diphenhydramine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Combinations; Ephedrine; Hypnotics and Sedatives; Male; Nonprescription Drugs; Psychomotor Performance; Rats; Rats, Sprague-Dawley | 1998 |
Simultaneous determination of dextromethorphan, diphenhydramine and phenylephrine in expectorant and decongestant syrups by capillary electrophoresis.
Topics: Chemistry, Pharmaceutical; Dextromethorphan; Diphenhydramine; Electrophoresis, Capillary; Expectorants; Nasal Decongestants; Phenylephrine | 2002 |
Abuse liability and stimulant properties of dextromethorphan and diphenhydramine combinations in rats.
Topics: Animals; Anti-Allergic Agents; Antitussive Agents; Dextromethorphan; Diphenhydramine; Dose-Response Relationship, Drug; Drug Interactions; Locomotion; Male; Rats; Rats, Sprague-Dawley; Self Administration | 2004 |
Over-the-counter cough and cold medicines: should parents be using them for their children?
Topics: Antitussive Agents; Child; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Humans; Nonprescription Drugs; Parents; Randomized Controlled Trials as Topic; Sleep | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Antitussive Agents; Cough; Dextromethorphan; Diphenhydramine; Humans; Placebo Effect; Placebos; Sucrose | 2004 |
Kids' cough drugs may not work.
Topics: Adult; Antitussive Agents; Child; Cost-Benefit Analysis; Cough; Dextromethorphan; Diphenhydramine; Humans | 2004 |
Do over-the-counter cough remedies work?
Topics: Antitussive Agents; Child; Dextromethorphan; Diphenhydramine; Humans; Nonprescription Drugs; Sleep Wake Disorders | 2004 |
Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.
Topics: Adolescent; Antitussive Agents; Child; Child, Preschool; Confounding Factors, Epidemiologic; Cough; Dextromethorphan; Diphenhydramine; Humans; Respiratory Tract Infections; Surveys and Questionnaires; Treatment Failure | 2005 |
Separation and determination of pseudoephedrine, dextromethorphan, diphenhydramine and chlorpheniramine in cold medicines by nonaqueous capillary electrophoresis.
Topics: Chlorpheniramine; Common Cold; Dextromethorphan; Diphenhydramine; Electrophoresis, Capillary; Ephedrine; Reproducibility of Results | 2005 |
Preparation and in vitro release of dual-drug resinates containing equivalent content dextromethorphan and diphenhydramine.
Topics: Anti-Allergic Agents; Antitussive Agents; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Dextromethorphan; Diphenhydramine; Drug Carriers; Drug Combinations; Drug Compounding; Ion Exchange Resins; Molecular Weight; Solubility; Surface Properties | 2006 |
A new hydrophilic interaction liquid chromatographic (HILIC) procedure for the simultaneous determination of pseudoephedrine hydrochloride (PSH), diphenhydramine hydrochloride (DPH) and dextromethorphan hydrobromide (DXH) in cough-cold formulations.
Topics: Acetates; Antitussive Agents; Buffers; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Dextromethorphan; Diphenhydramine; Drug Combinations; Ephedrine; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Indicators and Reagents; Nasal Decongestants; Pharmaceutical Solutions; Reference Standards; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet | 2007 |
FDA halts sales of some anti-vomiting suppositories...and are cough medications effective in children?
Topics: Adolescent; Antiemetics; Antitussive Agents; Benzamides; Child; Child, Preschool; Cough; Dextromethorphan; Diphenhydramine; Drug and Narcotic Control; Humans; Suppositories; Treatment Failure; United States; United States Food and Drug Administration | 2007 |
Best drugs for what ails you: the brands to buy--and those to skip.
Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Costs; Drug Therapy; Emergencies; Expectorants; First Aid; Glycerol; Guaifenesin; Histamine Antagonists; Honey; Humans; Hypersensitivity; Ibuprofen; Influenza Vaccines; Influenza, Human; Loratadine; Nonprescription Drugs; Oxymetazoline; Pharyngitis; Propiophenones; Pseudoephedrine; Rhinitis; Sodium Chloride | 2009 |
Fabrication and evaluation of cationic exchange nanofibers for controlled drug delivery systems.
Topics: Albuterol; Chlorpheniramine; Delayed-Action Preparations; Dextromethorphan; Diphenhydramine; Drug Delivery Systems; Gastric Juice; Hydrogen-Ion Concentration; Intestinal Secretions; Ion Exchange; Nanofibers; Polystyrenes; Propranolol | 2013 |
How often do false-positive phencyclidine urine screens occur with use of common medications?
Topics: Alprazolam; Carbazoles; Carvedilol; Clonazepam; Dextromethorphan; Diphenhydramine; Drug Interactions; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Humans; Phencyclidine; Propanolamines; Retrospective Studies; Substance-Related Disorders; Tramadol | 2013 |
Fatalities involving acetaminophen combination products reported to United States poison centers.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Databases, Factual; Dextromethorphan; Diphenhydramine; Dose-Response Relationship, Drug; Drug Combinations; Drug Overdose; Female; Humans; Male; Middle Aged; Poison Control Centers; Retrospective Studies; United States; Young Adult | 2013 |
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry | 2014 |
Elucidation of the orientation of selected drugs with 2-hydroxylpropyl-β-cyclodextrin using 2D-NMR spectroscopy and molecular modeling.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Calorimetry, Differential Scanning; Crystallography, X-Ray; Dextromethorphan; Diphenhydramine; Drug Compounding; Excipients; Freeze Drying; Lidocaine; Microscopy, Electron, Scanning; Molecular Docking Simulation; Molecular Dynamics Simulation; Pharmaceutical Preparations; Proton Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical | 2018 |
Medication Errors From Over-the-Counter Cough and Cold Medications in Children.
Topics: Child; Child, Preschool; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Utilization; Female; Humans; Infant; Male; Medication Errors; Nonprescription Drugs; Parents; Public Health Surveillance; United States | 2020 |
Trends in adverse events and related health-care facility utilization from cough and cold medication exposures in children.
Topics: Antitussive Agents; Child; Child, Preschool; Dextromethorphan; Diphenhydramine; Humans; Multi-Ingredient Cold, Flu, and Allergy Medications; Nonprescription Drugs; Patient Acceptance of Health Care; Poison Control Centers; United States | 2021 |
Pediatric Fatalities Associated With Over-the-Counter Cough and Cold Medications.
Topics: Antitussive Agents; Brompheniramine; Child; Child, Preschool; Chlorpheniramine; Dextromethorphan; Diphenhydramine; Doxylamine; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Female; Guaifenesin; Homicide; Humans; Infant; Male; Nonprescription Drugs; Phenylephrine; Pseudoephedrine | 2021 |