diphenhydramine and clemastine

diphenhydramine has been researched along with clemastine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199010 (55.56)18.7374
1990's1 (5.56)18.2507
2000's3 (16.67)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Shvarts, GIa1
Anisimov, VN1
Jankowska, R; Małolepszy, J; Szalaty, H1
Betti, R; Casanueva, FF; Cella, SG; Müller, EE1
Jankowska, R; Kraus-Filarska, M; Małolepszy, J; Szalaty, H1
Jacoby, BG; Wesley, RE1
Alonso, A; Colombi, PA1
Igarashi, T; Murakami, M; Shoji, T; Yamanaka, T1
Kurnatowski, P1
Betti, R; Casanueva, F; Chieli, T; Cocchi, D; Mantegazza, P; Müller, EE1
O'Hanlon, JF; Ramaekers, JG1
Ihrke, PJ; Kass, PH; White, SD; Zur, G1
El-Henawee, MM; Gouda, AA; Hassan, WS1

Reviews

1 review(s) available for diphenhydramine and clemastine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for diphenhydramine and clemastine

ArticleYear
Antihistamine effects on actual driving performance in a standard test: a summary of Dutch experience, 1989-94.
    Allergy, 1995, Volume: 50, Issue:3

    Topics: Automobile Driving; Benzimidazoles; Butyrophenones; Cetirizine; Clemastine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Loratadine; Netherlands; Piperidines; Psychomotor Performance; Terfenadine; Triprolidine

1995

Other Studies

16 other study(ies) available for diphenhydramine and clemastine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Effect of antihistaminics on bradykinin action].
    Biulleten' eksperimental'noi biologii i meditsiny, 1979, Volume: 88, Issue:10

    Topics: Aminopyridines; Animals; Benzhydryl Compounds; Bradykinin; Capillary Permeability; Clemastine; Diphenhydramine; Ethylenediamines; Guinea Pigs; Histamine H1 Antagonists; Ileum; Muscle, Smooth, Vascular; Phenothiazines; Promethazine; Pyridines; Pyridinolcarbamate; Pyrrolidines

1979
Influence of histamine on estrogen-induced inhibition of compensatory ovarian hypertrophy in hemiovariectomized rats.
    Endokrinologie, 1979, Volume: 73, Issue:1

    Topics: Amitrole; Animals; Brain; Castration; Clemastine; Diphenhydramine; Female; Histamine; Hypertrophy; Ovary; Rats

1979
Effect of antihistamines on interferon production by leukocytes from sensitized and non-sensitized mice.
    Archivum immunologiae et therapiae experimentalis, 1988, Volume: 36, Issue:3

    Topics: Animals; Clemastine; Diphenhydramine; Female; Histamine H1 Antagonists; Immunization; In Vitro Techniques; Interferons; Leukocytes; Male; Mice; Mice, Inbred BALB C; Pyrrolidines

1988
Activation of the cholinergic system and growth hormone release in the dog: functional interactions with other neurotransmitters.
    Acta endocrinologica, 1985, Volume: 108, Issue:1

    Topics: Animals; Behavior, Animal; Cimetidine; Clemastine; Diphenhydramine; Dogs; Domperidone; Female; Fenfluramine; Growth Hormone; Male; Metergoline; Naloxone; Phentolamine; Physostigmine; Pimozide; Pizotyline; Propranolol; Radioimmunoassay; Receptors, Cholinergic; Synaptic Transmission

1985
[Inhibition of the production of induced interferon in mice using Tavegyl and Benhydramin].
    Pneumonologia polska, 1988, Volume: 56, Issue:11

    Topics: Animals; Clemastine; Culture Media; Diphenhydramine; Female; In Vitro Techniques; Injections, Intraperitoneal; Interferon Type I; Male; Mice; Newcastle disease virus; Peritoneal Cavity; Pyrrolidines

1988
Painful orbital inflammatory lesions and mastocytosis.
    Annals of ophthalmology, 1987, Volume: 19, Issue:4

    Topics: Adolescent; Biopsy; Cimetidine; Clemastine; Combined Modality Therapy; Diphenhydramine; Drug Therapy, Combination; Female; Humans; Mastocytosis; Orbital Diseases; Skin; Ultraviolet Therapy

1987
[Action of diphenhydramine, chlorpheniramine, HS 592 and PB 400 on histamine and SRS-A induced wheals in skin of rats].
    Alergia, 1972, Volume: 20, Issue:2

    Topics: Anaphylaxis; Animals; Chlorpheniramine; Clemastine; Diphenhydramine; Histamine; Histamine H1 Antagonists; Maleates; Piperidines; Promethazine; Pyrrolidines; Rats; Serotonin Antagonists; SRS-A

1972
Effects of azelastine hydrochloride, a new antiallergic drug, on the gastrointestinal tract.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:8

    Topics: Animals; Bile; Clemastine; Digestive System; Diphenhydramine; Gastrointestinal Motility; Histamine H1 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Pancreatic Juice; Phthalazines; Pyridazines; Rats

1981
[In vitro antibacterial activity of drugs from the group of ethanolamine, phenothiazine and aminoalkyl derivatives with antihistaminic action].
    Acta poloniae pharmaceutica, 1984, Volume: 41, Issue:4

    Topics: Bacteria; Chlorpromazine; Clemastine; Dimenhydrinate; Diphenhydramine; Drug Resistance, Microbial; Ethanolamines; Histamine H1 Antagonists; In Vitro Techniques; Microbial Sensitivity Tests; Phenothiazines; Piperidines; Promethazine

1984
Proof for histaminergic but not for adrenergic involvement in the growth hormone-releasing effect of an enkephalin analog in the dog.
    Endocrinology, 1981, Volume: 108, Issue:1

    Topics: Animals; Cimetidine; Clemastine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Diphenhydramine; Dogs; Endorphins; Enkephalins; Female; Glucose; Growth Hormone; Histamine; Male; Phentolamine; Propranolol; Sympathetic Nervous System

1981
Antihistamines in the management of canine atopic dermatitis: a retrospective study of 171 dogs (1992-1998).
    Veterinary therapeutics : research in applied veterinary medicine, 2002,Spring, Volume: 3, Issue:1

    Topics: Allergens; Animals; Chlorpheniramine; Clemastine; Dermatitis, Atopic; Diphenhydramine; Dog Diseases; Dogs; Female; Histamine H1 Antagonists; Hydroxyzine; Male; Records; Retrospective Studies; Treatment Outcome

2002
Spectrophotometric determination of some histamine H1-antagonists drugs in their pharmaceutical preparations.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2008, Volume: 69, Issue:1

    Topics: Anthraquinones; Clemastine; Diphenhydramine; Dosage Forms; Ethylamines; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Kinetics; Pharmaceutical Preparations; Reproducibility of Results; Solvents; Spectrophotometry; Temperature; Time Factors

2008