diphenhydramine and chloroquine

diphenhydramine has been researched along with chloroquine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19908 (33.33)18.7374
1990's1 (4.17)18.2507
2000's7 (29.17)29.6817
2010's8 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Dietrich, FM; Komarek, A; Pericin, C1
Poste, G1
Greenham, LW; Poste, G1
Fujimura, H; Ito, M; Suzuki, Y; Yamagami, I2
Fukao, T; Takagi, K1
Hopkins, E; Hruban, Z; Slesers, A1
Lamela, M1
Jancinová, V; Májeková, M; Nosál, R; Petríková, M1
Jancinova, V; Nosal, R2
Huang, P; Mac, EA; Malkmus, S; Marino, M; Robertshaw, E; Shatterman, Y; Yaksh, TL1

Reviews

1 review(s) available for diphenhydramine and chloroquine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

23 other study(ies) available for diphenhydramine and chloroquine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Hypersensitivity in mice. II. The effect of chemical compounds on systemic active anaphylaxis and on anaphylaxis-like reactions in normal and B. pertussis-pretreated mice.
    International archives of allergy and applied immunology, 1971, Volume: 40, Issue:4-5

    Topics: Anaphylaxis; Animals; Antigens; Aspirin; Bordetella pertussis; Chloroquine; Corticosterone; Cortisone; Dexamethasone; Diphenhydramine; Flumethasone; gamma-Globulins; Histamine; Hydrocortisone; Hypersensitivity; Immunization, Secondary; Immunosuppressive Agents; Male; Methysergide; Mice; Muramidase; Ouabain; Paramethasone; Pertussis Vaccine; Prednisolone; Prednisone; Serotonin; Serum Albumin, Bovine; Tranquilizing Agents; Tripelennamine

1971
The role of lysosomes in virus-induced cell fusion. 2. Modification of the cell surface.
    Microbios, 1971, Volume: 3, Issue:10

    Topics: Aminocaproates; Animals; Cattle; Cell Fusion; Cell Line; Cell Wall; Cells, Cultured; Chloroquine; Diphenhydramine; Distemper Virus, Canine; Dogs; Enzyme Activation; Herpesviridae; Humans; Hydrocortisone; Lysosomes; Mastitis, Bovine; Respiratory Syncytial Viruses; Respirovirus; Simplexvirus

1971
The role of lysosomes in virus-induced cell fusion. 1. Cytochemical studies.
    Microbios, 1971, Volume: 3, Issue:10

    Topics: Aminocaproates; Animals; Cattle; Cell Fusion; Cell Line; Cells, Cultured; Chloroquine; Diphenhydramine; Distemper Virus, Canine; Dogs; Enzyme Activation; Herpesviridae; Histological Techniques; Humans; Hydrocortisone; Lysosomes; Mastitis, Bovine; Peptide Hydrolases; Respiratory Syncytial Viruses; Respirovirus; Simplexvirus

1971
[Influence of various drugs on the tissue permeability. 2].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1969, May-20, Volume: 65, Issue:3

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Barbiturates; Camphor; Cell Membrane Permeability; Chloroquine; Cyproheptadine; Dinitrophenols; Diphenhydramine; Drug Synergism; Imidazoles; Indomethacin; Injections, Subcutaneous; ortho-Aminobenzoates; Peptide Hydrolases; Piperazines; Rats; Rutin; Salicylates; Steroids; Sympatholytics

1969
[Influence of various drugs on tissue permeability. (4)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1970, Volume: 66, Issue:1

    Topics: Aminocaproates; Aminopyrine; Animals; Anti-Inflammatory Agents; Barbiturates; Chloroquine; Chymotrypsin; Coloring Agents; Connective Tissue; Cyclizine; Cyclohexanecarboxylic Acids; Cyproheptadine; Dexamethasone; Diphenhydramine; Flufenamic Acid; Glucocorticoids; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hyaluronoglucosaminidase; Indomethacin; Male; Peptide Hydrolases; Permeability; Phenylbutazone; Piperazines; Prednisolone; Protease Inhibitors; Rats; Salicylates

1970
Effects of some drugs on capillary permeability in the anaphylaxis of the mouse.
    Japanese journal of pharmacology, 1971, Volume: 21, Issue:4

    Topics: Aminopyrine; Anaphylaxis; Animals; Anti-Inflammatory Agents; Antilymphocyte Serum; Aprotinin; Aspirin; Body Temperature; Capillary Permeability; Chloroquine; Chlorpromazine; Cortisone; Cyclizine; Depression, Chemical; Desensitization, Immunologic; Diphenhydramine; Epinephrine; Female; Glycyrrhiza; Histamine H1 Antagonists; Indomethacin; Mice; Oxyphenbutazone; Phenylbutazone; Plants, Medicinal; Promethazine; Rectum; Reserpine; Splenectomy; Triprolidine

1971
Drug-induced and naturally occurring myeloid bodies.
    Laboratory investigation; a journal of technical methods and pathology, 1972, Volume: 27, Issue:1

    Topics: Amino Alcohols; Aminoglutethimide; Animals; Anticholesteremic Agents; Benzyl Compounds; Biphenyl Compounds; Chloroquine; Clofibrate; Cyclizine; Diphenhydramine; Endoplasmic Reticulum; Ethers; Haloperidol; Histamine H1 Antagonists; Hydroxyzine; Imidazoles; Inclusion Bodies; Kidney; Liver; Lysosomes; Male; Meclizine; Mice; Microscopy, Electron; Piperazines; Pyrrolidines; Rats; Triparanol; Trophoblasts

1972
Combined effects of antiarrhythmic drugs on the experimentally induced fibrillation of isolated rat's atria.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 157, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atropine; Chloroquine; Diphenhydramine; Heart Atria; Heart Rate; In Vitro Techniques; Phenformin; Quinidine; Rats; Sparteine

1965
Inhibition of blood platelet functions by cationic amphiphilic drugs in relation to their physico-chemical properties.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1996, Volume: 7, Issue:2

    Topics: Animals; Benzothiepins; Blood Platelets; Chemical Phenomena; Chemistry, Physical; Chloroquine; Diphenhydramine; Dose-Response Relationship, Drug; Platelet Aggregation Inhibitors; Platelet Function Tests; Propranolol; Radioimmunoassay; Rats; Software; Structure-Activity Relationship; Thrombin; Thromboxane B2

1996
Pharmacological intervention with platelet phospholipase A2.
    Bratislavske lekarske listy, 2001, Volume: 102, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Animals; Arachidonic Acid; Blood Platelets; Chloroquine; Dicarbethoxydihydrocollidine; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Activation; Histamine H1 Antagonists; Humans; Male; Membrane Lipids; Middle Aged; Phospholipases A; Phospholipases A2; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Surface-Active Agents

2001
Cationic amphiphilic drugs and platelet phospholipase A(2) (cPLA(2)).
    Thrombosis research, 2002, Feb-15, Volume: 105, Issue:4

    Topics: Alprenolol; Animals; Arachidonic Acid; Benzothiepins; Blood Platelets; Chloroquine; Diphenhydramine; Enzyme Activation; In Vitro Techniques; Male; Metipranolol; Phospholipases A; Phospholipases A2; Platelet Aggregation; Platelet Aggregation Inhibitors; Propranolol; Rats; Rats, Wistar; Surface-Active Agents

2002
Development and validation of an automated system for detection and assessment of scratching in the rodent.
    Journal of neuroscience methods, 2012, Oct-15, Volume: 211, Issue:1

    Topics: Algorithms; Analog-Digital Conversion; Animals; Anti-Allergic Agents; Automation; Behavior, Animal; Chloroquine; Data Interpretation, Statistical; Diphenhydramine; Electromagnetic Fields; Foot; Histamine; Male; Mice; Mice, Inbred C57BL; Motion; p-Methoxy-N-methylphenethylamine; Pruritus; Psychology, Experimental; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Signal Processing, Computer-Assisted

2012