diphenhydramine and benztropine

diphenhydramine has been researched along with benztropine in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (58.06)	18.7374
1990's	7 (22.58)	18.2507
2000's	3 (9.68)	29.6817
2010's	3 (9.68)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Feldman, S; Putcha, L	1
Lee, AS	1
Butzer, JF; Sahs, AL; Silver, DE	1
Brady, W; Hall, K	1
Francom, M	1
Knight, ME; Roberts, RJ	1
Bailie, GR; Krenzelok, EP; Lesar, T; Nelson, MV	1
Civil, RH; Foley, JM; Leigh, RJ; Remler, BF	1
Brower, KJ	1
Nose, T; Segawa, T	1
Sheehan, DV	1
Heikkila, RE; Orlansky, H	1
Nymark, M	1
Ray, I	1
McKearney, JW	2
Dahiya, U; Noronha, P	1
Carey, RJ	2
Bessen, HA; Corre, KA; Niemann, JT	1
Joseph, MM; King, WD	1
Lang, AE	1
Kuo, CC	1
Hasan, MY; Holmes, CH; Schauben, JL	1
Burda, A; Chan, SB; Leikin, JB; Stokes, KA; Webster, K	1
Jackson, CW; Markowitz, JS; McLeod-Bryant, S	1
Aravagiri, M; Arroyo, LG; Baird, JD; Kenney, DG; Maylin, GA; McGurrin, MK; Rodriguez-Palacios, A; Vengust, M	1

Reviews

2 review(s) available for diphenhydramine and benztropine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Phenothiazine and butyrophenone intoxication in children. Pediatric clinics of North America, 1986, Volume: 33, Issue:2 Topics: Absorption; Adolescent; Basal Ganglia Diseases; Benztropine; Butyrophenones; Cardiovascular System; Central Nervous System; Charcoal; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Coma; Dantrolene; Diagnosis, Differential; Diphenhydramine; Female; Gastric Lavage; Humans; Ipecac; Kinetics; Liver; Neuroleptic Malignant Syndrome; Phenothiazines; Photosensitivity Disorders	1986

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Phenothiazine and butyrophenone intoxication in children.

Pediatric clinics of North America, 1986, Volume: 33, Issue:2

Topics: Absorption; Adolescent; Basal Ganglia Diseases; Benztropine; Butyrophenones; Cardiovascular System; Central Nervous System; Charcoal; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Coma; Dantrolene; Diagnosis, Differential; Diphenhydramine; Female; Gastric Lavage; Humans; Ipecac; Kinetics; Liver; Neuroleptic Malignant Syndrome; Phenothiazines; Photosensitivity Disorders

1986

Trials

2 trial(s) available for diphenhydramine and benztropine

Article	Year
Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up. Neurology, 1975, Volume: 25, Issue:7 Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine; Drug Evaluation; Female; Follow-Up Studies; Humans; Locomotion; Long-Term Care; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Procyclidine; Time Factors; Tremor; Trihexyphenidyl	1975
Antihistaminics in idiopathic dystonia. Archives of neurology, 1996, Volume: 53, Issue:5 Topics: Adult; Atropine; Benztropine; Chlorpheniramine; Cholinergic Antagonists; Diphenhydramine; Double-Blind Method; Dystonia; Histamine H1 Antagonists; Humans	1996

Article

Year

Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up.

Neurology, 1975, Volume: 25, Issue:7

Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine; Drug Evaluation; Female; Follow-Up Studies; Humans; Locomotion; Long-Term Care; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Procyclidine; Time Factors; Tremor; Trihexyphenidyl

1975

Antihistaminics in idiopathic dystonia.

Archives of neurology, 1996, Volume: 53, Issue:5

Topics: Adult; Atropine; Benztropine; Chlorpheniramine; Cholinergic Antagonists; Diphenhydramine; Double-Blind Method; Dystonia; Histamine H1 Antagonists; Humans

1996

Other Studies

27 other study(ies) available for diphenhydramine and benztropine

Article	Year
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Effect of anti-parkinsonism drugs on gastric emptying and intestinal transit in the rat. Pharmacology, 1977, Volume: 15, Issue:6 Topics: Administration, Oral; Animals; Antiparkinson Agents; Atropine; Benztropine; Diphenhydramine; Gastric Emptying; Gastrointestinal Motility; Injections, Intraperitoneal; Male; Parasympatholytics; Phenolsulfonphthalein; Phenothiazines; Rats; Trihexyphenidyl	1977
Treatment of drug-induced dystonic reactions. JACEP, 1979, Volume: 8, Issue:11 Topics: Adolescent; Adult; Benztropine; Diphenhydramine; Dystonia; Female; Haloperidol; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Prospective Studies; Substance-Related Disorders	1979
Erythromycin-related dystonic reaction. The American journal of emergency medicine, 1992, Volume: 10, Issue:6 Topics: Adult; Benztropine; Diphenhydramine; Dystonia; Erythromycin Ethylsuccinate; Humans; Male	1992
Compounding nausea aid. American pharmacy, 1991, Volume: NS31, Issue:7 Topics: Benztropine; Chemistry, Pharmaceutical; Dexamethasone; Diphenhydramine; Drug Combinations; Drug Compounding; Haloperidol; Humans; Lorazepam; Metoclopramide; Nausea; Suppositories; Vomiting	1991
Unusual treatment response of a severe dystonia to diphenhydramine. Annals of emergency medicine, 1987, Volume: 16, Issue:6 Topics: Adult; Benztropine; Delayed-Action Preparations; Diphenhydramine; Dystonia; Fluphenazine; Humans; Male; Mental Disorders	1987
Oculogyric crisis: a syndrome of thought disorder and ocular deviation. Annals of neurology, 1987, Volume: 22, Issue:1 Topics: Adult; Benztropine; Cognition Disorders; Diphenhydramine; Eye Movements; Female; Humans; Male; Middle Aged; Parasympatholytics; Syndrome	1987
Smoking of prescription anticholinergic drugs. The American journal of psychiatry, 1987, Volume: 144, Issue:3 Topics: Adult; Benztropine; Diphenhydramine; Humans; Male; Schizophrenic Psychology; Smoking; Substance-Related Disorders; Tropanes	1987
A comparison of the inhibitory effects of certain antiparkinsonian agents on dopamine accumulation into the rat striatum. Japanese journal of pharmacology, 1974, Volume: 24, Issue:2 Topics: Animals; Antidepressive Agents; Antiparkinson Agents; Atropine; Benztropine; Chlorpromazine; Corpus Striatum; Diphenhydramine; Dopamine; Glycolates; Male; Mitochondria; Ouabain; Phenothiazines; Rats; Trihexyphenidyl	1974
The use of antihistamines for the alleviation of urinary retention caused by psychotropic drugs. Canadian Psychiatric Association journal, 1972, Volume: 17, Issue:5 Topics: Adolescent; Antiparkinson Agents; Benztropine; Diphenhydramine; Haloperidol; Histamine H1 Antagonists; Humans; Male; Middle Aged; Urination Disorders	1972
An evaluation of various antiparkinsonian agents as releasing agents and uptake inhibitors for 3H-dopamine in slices of rat neostriatum. European journal of pharmacology, 1974, Volume: 29, Issue:2 Topics: Animals; Antiparkinson Agents; Benztropine; Catecholamines; Caudate Nucleus; Cerebral Cortex; Corpus Striatum; Diphenhydramine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Orphenadrine; Putamen; Rats; Serotonin; Trihexyphenidyl; Tritium	1974
Apomorphine provoked stereotype in the dog. Psychopharmacologia, 1972, Volume: 26, Issue:4 Topics: Amitriptyline; Animals; Anisoles; Apomorphine; Atropine; Behavior, Animal; Benzamides; Benztropine; Diazepam; Diphenhydramine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Ethylamines; Female; Fluphenazine; Haloperidol; Humans; Male; Methyltyrosines; Motor Activity; Phenoxybenzamine; Piperazines; Receptors, Drug; Scopolamine; Stereotyped Behavior; Xanthenes	1972
Combinations of antidepressant drugs in the treatment of depressive illness. Canadian Psychiatric Association journal, 1973, Volume: 18, Issue:5 Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents; Benztropine; Canada; Chlorpromazine; Depression; Dibenzazepines; Diphenhydramine; Drug Synergism; Drug Therapy, Combination; Electroconvulsive Therapy; Evaluation Studies as Topic; Female; Humans; Male; Methaqualone; Middle Aged; Phenelzine; Retrospective Studies; Sleep; Tranylcypromine	1973
Stimulant actions of histamine H1 antagonists on operant behavior in the squirrel monkey. Psychopharmacology, 1982, Volume: 77, Issue:2 Topics: Animals; Benztropine; Conditioning, Operant; Diphenhydramine; Histamine H1 Antagonists; Male; Promethazine; Reinforcement Schedule; Saimiri; Stimulation, Chemical	1982
Drug-induced acute dystonic reactions in children. Alternatives to diphenhydramine therapy. Postgraduate medicine, 1984, Volume: 75, Issue:5 Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Child; Child, Preschool; Creatine Kinase; Diazepam; Diphenhydramine; Dystonia; Humans; Phenothiazines; Tropanes	1984
Reversal of haloperidol induced deficits in self-stimulation by anti-Parkinsonian drugs. Behavioural brain research, 1983, Volume: 10, Issue:2-3 Topics: Animals; Benztropine; Diphenhydramine; Electric Stimulation; Extinction, Psychological; Haloperidol; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Self Stimulation; Synaptic Transmission; Tropanes	1983
Extended therapy for acute dystonic reactions. Annals of emergency medicine, 1984, Volume: 13, Issue:3 Topics: Acute Disease; Adult; Benztropine; Biperiden; Diphenhydramine; Dystonia; Female; Humans; Jaw; Male; Recurrence; Trihexyphenidyl; Trismus	1984
A comparison of atropine, benztropine and diphenhydramine on the reversal of haloperidol induced suppression of self-stimulation. Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:4 Topics: Animals; Atropine; Benztropine; Diphenhydramine; Haloperidol; Kinetics; Male; Rats; Rats, Inbred Strains; Reinforcement, Psychology; Self Stimulation; Tropanes	1982
Individual differences in effects of tricyclic antidepressants and anticholinergic drugs on operant behavior in the squirrel monkey. Life sciences, 1981, May-04, Volume: 28, Issue:18 Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Atropine; Behavior, Animal; Benztropine; Brain; Cebidae; Diphenhydramine; Male; Parasympatholytics; Saimiri	1981
Dystonic reaction following recommended use of a cold syrup. Annals of emergency medicine, 1995, Volume: 26, Issue:6 Topics: Benztropine; Child, Preschool; Diphenhydramine; Drug Combinations; Dystonia; Histamine H1 Antagonists; Humans; Male; Nasal Decongestants; Phenylpropanolamine	1995
Imipramine inhibition of transient K+ current: an external open channel blocker preventing fast inactivation. Biophysical journal, 1998, Volume: 75, Issue:6 Topics: Animals; Antidepressive Agents, Tricyclic; Benztropine; Binding Sites; Biophysical Phenomena; Biophysics; Diphenhydramine; Hippocampus; Hydrogen-Ion Concentration; Imipramine; In Vitro Techniques; Ion Channel Gating; Kinetics; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Protein Conformation; Rats	1998
Management of neuroleptic malignant syndrome with anticholinergic medication. Veterinary and human toxicology, 1999, Volume: 41, Issue:2 Topics: Adolescent; Benztropine; Cholinergic Antagonists; Diphenhydramine; Female; Fever; Fluphenazine; Humans; Lithium Chloride; Neuroleptic Malignant Syndrome	1999
Nefazadone-induced acute dystonic reaction. Veterinary and human toxicology, 1999, Volume: 41, Issue:5 Topics: Antidepressive Agents, Second-Generation; Antiemetics; Benztropine; Diphenhydramine; Drug Interactions; Dystonia; Female; Humans; Meclizine; Middle Aged; Parasympatholytics; Piperazines; Time Factors; Triazoles	1999
Cost savings with intramuscular anticholinergics. The Journal of clinical psychiatry, 2001, Volume: 62, Issue:4 Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Cholinergic Antagonists; Cost Savings; Diphenhydramine; Drug Costs; Drugs, Generic; Hospital Costs; Humans; Injections, Intramuscular; Mental Disorders; Pharmacy Service, Hospital	2001
Adverse extrapyramidal effects in four horse given fluphenazine decanoate. Journal of the American Veterinary Medical Association, 2006, Jul-01, Volume: 229, Issue:1 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benztropine; Diphenhydramine; Extrapyramidal Tracts; Fatal Outcome; Female; Fluphenazine; Horse Diseases; Horses; Male; Nervous System Diseases; Treatment Outcome	2006